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Product Details
16274-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ATP6V1C2 Fusion Protein Ag9349 (1-381 aa encoded by BC012142)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSEFWLISA PGDKENLQAL ERMNTVTSKS NLSYNTKFAI PDFKVGTLDS LVGLSDELGK LDTFAESLIR RMAQSVVEVM EDSKGKVQEH LLANGVDLTS FVTHFEWDMA KYPVKQPLVS VVDTIAKQLA QIEMDLKSRT AAYDTLKTNL ENLEKKSMGN LFTRTLSDIV SKEDFVLDSE YLVTLLVIVP KPNYSQWQKT YESLSDMVVP RSTKLITEDK EGGLFTVTLF RKVIEDFKTK AKENKFTVRE FYYDEKEIER EREEMARLLS DKKQQYGPLL RWLKVNFSEA FIAWIHIKAL RVFVESVLRY GLPVNFQAVL LQPHKKSSTK RLREVLNSVF RHLDEVAATS ILDASVEIPG LQLNNQDYFP YVYFHIDLSL LD (1-381 aa encoded by BC012142)
Target Information
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, V1 subunit C, isoform 2; V-ATPase C2 subunit; V-ATPase subunit C 2; V-type proton ATPase subunit C 2; Vacuolar proton pump subunit C 2
Gene Aliases: 1110038G14Rik; ATP6C2; ATP6V1C2; VMA5
UniProt ID: (Human) Q8NEY4, (Mouse) Q99L60
Entrez Gene ID: (Human) 245973, (Mouse) 68775
insulin receptor signaling pathway
ATP hydrolysis coupled proton transport
regulation of macroautophagy
positive regulation of Wnt signaling pathway
transferrin transport
ion transmembrane transport
phagosome acidification
transport
ion transport
proton transport
hydrogen ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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