Proteintech

ATPB Polyclonal Antibody

ATPB Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

ATPB Antibody (17247-1-AP) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HeLa cells using ATPB antibody (Product # 17247-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

ATPB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

ATPB Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

17247-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 42 publications 42 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

Immunocytochemistry (ICC/IF)

1:20-1:200

View 4 publications 4 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ATPB Fusion Protein Ag11177 (181-529 aa encoded by BC016512)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: EILVTGIKV VDLLAPYAKG GKIGLFGGAG VGKTVLIMEL INNVAKAHGG YSVFAGVGER TREGNDLYHE MIESGVINLK DATSKVALVY GQMNEPPGAR ARVALTGLTV AEYFRDQEGQ DVLLFIDNIF RFTQAGSEVS ALLGRIPSAV GYQPTLATDM GTMQERITTT KKGSITSVQA IYVPADDLTD PAPATTFAHL DATTVLSRAI AELGIYPAVD PLDSTSRIMD PNIVGSEHYD VARGVQKILQ DYKSLQDIIA ILGMDELSEE DKLTVSRARK IQRFLSQPFQ VAEVFTGHMG KLVPLKETIK GFQQILAGEY DHLPEQAFYM VGPIEEAVAK ADKLAEEHSS (181-529 aa encoded by BC016512)

Target Information

ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness.

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Richter U,Lahtinen T,Marttinen P,Suomi F,Battersby BJ

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Quantitative changes in Gimap3 and Gimap5 expression modify mitochondrial DNA segregation in mice.

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Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.

ACS chemical biology

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Fri Apr 18 00:00:00 EDT 2014

Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.

ACS chemical biology

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Fri Apr 18 00:00:00 EDT 2014

Cruentaren A binds F1F0 ATP synthase to modulate the Hsp90 protein folding machinery.

ACS chemical biology

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Liver international : official journal of the International Association for the Study of the Liver

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Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders.

Liver international : official journal of the International Association for the Study of the Liver

Preuss B,Berg C,Dengjel J,Stevanovic S,Klein R

Wed Feb 01 00:00:00 EST 2012

Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders.

Liver international : official journal of the International Association for the Study of the Liver

Preuss B,Berg C,Dengjel J,Stevanovic S,Klein R

Wed Feb 01 00:00:00 EST 2012

Relevance of the inner mitochondrial membrane enzyme F1F0-ATPase as an autoantigen in autoimmune liver disorders.

Liver international : official journal of the International Association for the Study of the Liver

Preuss B,Berg C,Dengjel J,Stevanovic S,Klein R

Wed Feb 01 00:00:00 EST 2012

Bioinformatics

Protein Aliases: ATP synthase F1 subunit beta; ATP synthase subunit beta, mitochondrial; ATP synthase, H+ transporting mitochondrial F1 complex, alpha subunit; ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit; epididymis secretory protein Li 271; MGC5231; mitochondrial ATP synthase beta subunit; mitochondrial ATP synthase, H+ transporting F1 complex beta subunit; mitochondrial ATP synthetase, beta subunit

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Gene Aliases: ATP5B; ATP5F1B; ATPMB; ATPSB; HEL-S-271

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UniProt ID: (Human) P06576, (Rat) P10719, (Mouse) P56480

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Entrez Gene ID: (Human) 506, (Rat) 171374, (Mouse) 11947

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Function(s)

transporter activity protein binding ATP binding ATPase activity transmembrane transporter activity MHC class I protein binding proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism calcium ion binding lipoprotein particle receptor activity nucleotide binding hydrolase activity hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances ATP synthase

Process(es)

angiogenesis osteoblast differentiation generation of precursor metabolites and energy lipid metabolic process ATP biosynthetic process negative regulation of cell adhesion involved in substrate-bound cell migration mitochondrion organization ATP hydrolysis coupled proton transport proton transport mitochondrial ATP synthesis coupled proton transport regulation of intracellular pH receptor-mediated endocytosis ATP synthesis coupled proton transport ATP metabolic process transport ion transport hydrogen ion transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ATPB Polyclonal Antibody

ATPB Antibody (17247-1-AP) in ICC/IF

Product Details

17247-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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