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Product Details
10130-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Adaptin Fusion Protein Ag0011
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adapter-related protein complex 1 subunit beta-1; Adaptor protein complex AP-1 subunit beta-1; adaptor-related protein complex 1 beta 1 subunit; Adaptor-related protein complex 1 subunit beta-1; adaptor-related protein complex 1, beta 1 subunit; AP-1 complex subunit beta-1; Beta-1-adaptin; Beta-adaptin 1; beta-prime-adaptin; beta1-adaptin; Clathrin assembly protein complex 1 beta large chain; Golgi adaptor HA1/AP1 adaptin beta subunit; plasma membrane adaptor HA2/AP2 adaptor beta subunit
Gene Aliases: ADTB1; AP105A; AP1B1; BAM22; CLAPB2
UniProt ID: (Human) Q10567
Entrez Gene ID: (Human) 162
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