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Invitrogen
Aldolase A Recombinant Rabbit Monoclonal Antibody (JM54-19)
Advanced Verification
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 11
Aldolase A Antibody (MA5-41240) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of Aldolase-A in SK-Br-3 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with Aldolase A Recombinant Monoclonal Antibody (Product # MA5-41240) at a dilution of 1:50 for 1 hour at room temperature, washed ... View More
Product Details
MA5-41240
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JM54-19
Immunogen
Synthetic peptide within N-terminal human Aldolase
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2898993
Target Information
Aldolase encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aldolase 1; aldolase 1, A isoform; aldolase A, fructose-bisphosphate; epididymis secretory sperm binding protein Li 87p; fructose-1,6-bisphosphate triosephosphate-lyase; Fructose-bisphosphate aldolase A; Lung cancer antigen NY-LU-1; Muscle-type aldolase
Gene Aliases: ALDA; Aldo-1; Aldo1; ALDOA; GSD12; HEL-S-87p; RNALDOG5
UniProt ID: (Human) P04075, (Mouse) P05064, (Rat) P05065
Entrez Gene ID: (Human) 226, (Mouse) 11674, (Rat) 24189
platelet degranulation
fructose metabolic process
gluconeogenesis
glycolytic process
ATP biosynthetic process
striated muscle contraction
actin filament organization
regulation of cell shape
fructose 1,6-bisphosphate metabolic process
muscle cell cellular homeostasis
protein homotetramerization
canonical glycolysis
cell-cell adhesion
response to hypoxia
response to heat
response to lipopolysaccharide
response to nicotine
response to estrogen
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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