Product References
Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin-expressing interneurons, and inhibitory function in the auditory cortex.
Glia
Borges BC,Meng X,Long P,Kanold PO,Corfas G
A-11094 was used in Immunohistochemistry-immunofluorescence to indicate that mild hypomyelination impacts A1 neuronal networks, reducing inhibitory activity, and shifting networks towards excitation.
Wed Feb 01 00:00:00 EST 2023
Heat denaturation enables multicolor X10-STED microscopy.
Scientific reports
Saal KA,Shaib AH,Mougios N,Crzan D,Opazo F,Rizzoli SO
A-11094 was used in Immunohistochemistry-immunofluorescence to present a expansion microscopy protocol that ensures the expansion of the samples up to 10-fold, in a single expansion step, through high-temperature homogenization (X10ht).
Sat Apr 01 00:00:00 EDT 2023
In vivo biocompatibility analysis of the recellularized canine tracheal scaffolds with canine epithelial and endothelial progenitor cells.
Bioengineered
de Sá Schiavo Matias G,Carreira ACO,Batista VF,de Carvalho HJC,Miglino MA,Fratini P
A-11094 was used in Immunocytochemistry to show the recellularization success due the preserved ECM proteins, and that these may be suitable to future preclinical studies applications for partial trachea replacement in tissue engineering.
Tue Feb 01 00:00:00 EST 2022
Distinct Contribution of Granular and Agranular Subdivisions of the Retrosplenial Cortex to Remote Contextual Fear Memory Retrieval.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tsai TC,Yu TH,Hung YC,Fong LI,Hsu KS
A-11094 was used in Immunohistochemistry to support the hypothesis that the RSC and hippocampus require each other to preserve fear memories and may provide a novel therapeutic avenue to attenuate remote traumatic memories in patients with post-traumatic stress disorder.
Wed Feb 02 00:00:00 EST 2022
A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90.
Disease models & mechanisms
Ngo V,Brickenden A,Liu H,Yeung C,Choy WY,Duennwald ML
A-11094 was used in Immunocytochemistry to study interactions between Nrf2, Keap1, and Hsp90 in yeast.
Fri Apr 01 00:00:00 EDT 2022
Trispecific antibodies produced from mAb2 pairs by controlled Fab-arm exchange.
Biological chemistry
Natale V,Stadlmayr G,Benedetti F,Stadlbauer K,Rüker F,Wozniak-Knopp G
A-11094 was used in Flow Cytometry to employ symmetrical bispecific parental antibodies of mAb2 format, which feature a novel antigen binding site in the CH3 domains, and engineered them with a minimal number of point mutations to guide the formation of a controlled Fab-arm exchanged trispecific antibody at a high yield after reduction and re-oxidation.
Tue Apr 26 00:00:00 EDT 2022
High glutamine suppresses osteogenesis through mTORC1-mediated inhibition of the mTORC2/AKT-473/RUNX2 axis.
Cell death discovery
Gayatri MB,Gajula NN,Chava S,Reddy ABM
A-11094 was used in Western Blotting to indicate the role of glutamine in modulating MSC fate through cross-talk between mTOR complexes by identifying a critical switch in signaling and the importance of glutamine in modulating molecular cues (mTORC1/p-70S6K/mTORC2/RUNX2) that are involved in driving diabetes-induced bone adipogenesis and other secondary complications.
Tue Jun 07 00:00:00 EDT 2022
midline represses Dpp signaling and target gene expression in Drosophila ventral leg development.
Biology open
Phillips LA,Atienza ML,Ryu JR,Svendsen PC,Kelemen LK,Brook WJ
A-11094 was used in Immunohistochemistry to show that midline represses the Dpp-activated gene Daughters against decapentaplegic (Dad) through a consensus T-box binding element (TBE) site in the minimal enhancer, Dad13.
Sun May 15 00:00:00 EDT 2022
Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1.
Antioxidants (Basel, Switzerland)
Ngo V,Karunatilleke NC,Brickenden A,Choy WY,Duennwald ML
A-11094 was used in Immunocytochemistry-immunofluorescence to reveal previously unexplored aspects of Nrf2 and Keap1 regulation and/or dysregulation by oxidation-induced protein misfolding.
Thu Jan 27 00:00:00 EST 2022
Sec3 exocyst component knockdown inhibits axonal formation and cortical neuronal migration during brain cortex development.
Journal of neurochemistry
Bustos Plonka F,Sosa LJ,Quiroga S
A-11094 was used in Immunohistochemistry-immunofluorescence to emonstrate that the exocyst complex protein Sec3 plays an important role in axon formation in neuronal differentiation and the migration of neuronal progenitors during cortex development.
Sat Jan 01 00:00:00 EST 2022
CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X.
Cell reports
Hwang JY,Monday HR,Yan J,Gompers A,Buxbaum AR,Sawicka KJ,Singer RH,Castillo PE,Zukin RS
A-11094 was used in Immunohistochemistry-immunofluorescence to show that mRNA encoding the AMPAR subunit GluA2 (but not GluA1) is elevated in dendrites and at transcription sites of hippocampal neurons of Fmr1 KO mice, indicating elevated GluA2 transcription and identify CPEB3, a protein implicated in memory consolidation, as an upstream effector critical to GluA2 mRNA expression in FXS.
Tue Jun 07 00:00:00 EDT 2022
Mitoribosomal Deregulation Drives Senescence via TPP1-Mediated Telomere Deprotection.
Cells
Min S,Kwon SM,Hong J,Lee YK,Park TJ,Lim SB,Yoon G
A-11094 was used in Western Blotting to indicate that mitoribosomal deregulation could represent an early event initiating mitochondrial dysfunction and serve as a primary driver of cellular senescence and an upstream regulator of shelterin-mediated telomere deprotection.
Thu Jun 30 00:00:00 EDT 2022
In vivo overexpression of frataxin causes toxicity mediated by iron-sulfur cluster deficiency.
Molecular therapy. Methods & clinical development
Huichalaf C,Perfitt TL,Kuperman A,Gooch R,Kovi RC,Brenneman KA,Chen X,Hirenallur-Shanthappa D,Ma T,Assaf BT,Pardo I,Franks T,Monarski L,Cheng TW,Le K,Su C,Somanathan S,Whiteley LO,Bulawa C,Pregel MJ,Martelli A
A-11094 was used in Immunohistochemistry to provide insights into the toxicity of frataxin overexpression that should be considered in the development of a gene therapy approach for Friedreich's ataxia.
Thu Mar 10 00:00:00 EST 2022
Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice.
iScience
Qiao H,Tian Y,Huo Y,Man HY
A-11094 was used in Immunohistochemistry to provide new insights in USP7-related neurobiological functions and its implication in ASD.
Fri Jul 15 00:00:00 EDT 2022
Interactions between Brainstem Neurons That Regulate the Motility to the Stomach.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Bellusci L,Garcia DuBar SN,Kuah M,Castellano D,Muralidaran V,Jones E,Rozeboom AM,Gillis RA,Vicini S,Sahibzada N
A-11094 was used in Immunohistochemistry-immunofluorescence to indicate that interacting NPY and SST neurons are integral to the network that controls vagal transmission to the stomach.
Wed Jun 29 00:00:00 EDT 2022
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.
Autophagy
Peña-Oyarzun D,Rodriguez-Peña M,Burgos-Bravo F,Vergara A,Kretschmar C,Sotomayor-Flores C,Ramirez-Sarmiento CA,De Smedt H,Reyes M,Perez W,Torres VA,Morselli E,Altamirano F,Wilson CAM,Hill JA,Lavandero S,Criollo A
A-11094 was used in Immunocytochemistry to show that the PKD2-BECN1 complex is required for the induction of autophagy, and its formation depends on the presence of the CC1 domain of PKD2 and on intracellular Ca2+ mobilization by PKD2.
Thu Jul 01 00:00:00 EDT 2021
NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase.
PLoS pathogens
Dong L,Dong J,Xiang M,Lei P,Li Z,Zhang F,Sun X,Niu D,Bai L,Lan K
A-11094 was used in Immunocytochemistry to conclude that NDRG1 is a novel binding partner of ORF44 and facilitates viral lytic replication by maintaining the stability of ORF44.
Tue Jun 01 00:00:00 EDT 2021
TRPM8 Channel Promotes the Osteogenic Differentiation in Human Bone Marrow Mesenchymal Stem Cells.
Frontiers in cell and developmental biology
Henao JC,Grismaldo A,Barreto A,Rodríguez-Pardo VM,Mejía-Cruz CC,Leal-Garcia E,Pérez-Núñez R,Rojas P,Latorre R,Carvacho I,Torres YP
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunocytochemistry
Tue Feb 23 00:00:00 EST 2021
Selection of tumor‑resistant variants following sustained natural killer cell‑mediated immune stress.
Oncology reports
Carré T,Thiery J,Janji B,Terry S,Gros G,Meurice G,Kieda C,Olive D,Chouaib S
A-11094 was used in Immunocytochemistry to study the role of NK cells which may span far beyond the mere killing of malignant cells, and NK cells may be important effectors during cancer immunoediting.
Mon Feb 01 00:00:00 EST 2021
Chronic Alcohol Use Induces Molecular Genetic Changes in the Dorsomedial Thalamus of People with Alcohol-Related Disorders.
Brain sciences
Hade AC,Philips MA,Reimann E,Jagomäe T,Eskla KL,Traks T,Prans E,Kõks S,Vasar E,Väli M
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunohistochemistry
Mon Mar 29 00:00:00 EDT 2021
Chronic Alcohol Use Induces Molecular Genetic Changes in the Dorsomedial Thalamus of People with Alcohol-Related Disorders.
Brain sciences
Hade AC,Philips MA,Reimann E,Jagomäe T,Eskla KL,Traks T,Prans E,Kõks S,Vasar E,Väli M
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunohistochemistry
Mon Mar 29 00:00:00 EDT 2021
Fibrillar pharmacology of functionalized nanocellulose.
Scientific reports
Wong S,Alidori S,Mello BP,Almeida BA,Ulmert D,Brendel MB,Scheinberg DA,McDevitt MR
A-11094 was used in Immunohistochemistry (Paraffin) to suggest that functionalized nanocellulose can be used as a potential drug delivery platform for the kidneys.
Fri Jan 08 00:00:00 EST 2021
Fibrillar pharmacology of functionalized nanocellulose.
Scientific reports
Wong S,Alidori S,Mello BP,Almeida BA,Ulmert D,Brendel MB,Scheinberg DA,McDevitt MR
A-11094 was used in Immunohistochemistry (Paraffin) to suggest that functionalized nanocellulose can be used as a potential drug delivery platform for the kidneys.
Fri Jan 08 00:00:00 EST 2021
MRPS31 loss is a key driver of mitochondrial deregulation and hepatocellular carcinoma aggressiveness.
Cell death & disease
Min S,Lee YK,Hong J,Park TJ,Woo HG,Kwon SM,Yoon G
A-11094 was used in Western Blot to provide new mechanistic insight for mitochondrial deregulation in HCC and present MRPS31 as a novel biomarker of HCC malignancy.
Fri Nov 12 00:00:00 EST 2021
MRPS31 loss is a key driver of mitochondrial deregulation and hepatocellular carcinoma aggressiveness.
Cell death & disease
Min S,Lee YK,Hong J,Park TJ,Woo HG,Kwon SM,Yoon G
A-11094 was used in Western Blot to provide new mechanistic insight for mitochondrial deregulation in HCC and present MRPS31 as a novel biomarker of HCC malignancy.
Fri Nov 12 00:00:00 EST 2021
Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons.
eLife
Arttamangkul S,Platt EJ,Carroll J,Farrens D
A-11094 was used in Western Blot to indicate that while MORs and DORs are expressed in single striatal cholinergic interneurons, the two receptors function independently.
Fri Sep 03 00:00:00 EDT 2021
NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cells.
Cell reports. Medicine
Geles KG,Gao Y,Giannakou A,Sridharan L,Yamin TT,Zhang J,Karim R,Bard J,Piche-Nicholas N,Charati M,Maderna A,Lucas J,Golas J,Guffroy M,Pirie-Shepherd S,Roy M,Qian J,Franks T,Zhong W,O'Donnell CJ,Tchistiakova L,Gerber HP,Sapra P
A-11094 was used in Immunohistochemistry to develop NOTCH3 antibody drug conjugates for use in targeting NOTCH3-dependent tumours.
Tue May 18 00:00:00 EDT 2021
Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity.
Nature metabolism
Porniece Kumar M,Cremer AL,Klemm P,Steuernagel L,Sundaram S,Jais A,Hausen AC,Tao J,Secher A,Pedersen TÅ,Schwaninger M,Wunderlich FT,Lowell BB,Backes H,Brüning JC
A-11094 was used in Immunohistochemistry to reveal a critical role of tanycyte insulin receptors in gating feeding-state-dependent regulation of AgRP neurons and systemic insulin sensitivity, and show that insulin resistance in tanycytes contributes to the pleiotropic manifestations of obesity-associated insulin resistance.
Wed Dec 01 00:00:00 EST 2021
Natural podophyllotoxin analog 4DPG attenuates EMT and colorectal cancer progression via activation of checkpoint kinase 2.
Cell death discovery
Katoch A,Nayak D,Faheem MM,Kumar A,Sahu PK,Gupta AP,Kumar LD,Goswami A
A-11094 was used in Immunocytochemistry-immunoflourescence to demonstrate 4DPG as a targeted antitumor/anti-metastatic pharmacological lead compound to circumvent EMT-associated drug resistance and suggest its clinical benefits for the treatment of aggressive cancers.
Tue Jan 26 00:00:00 EST 2021
Local application of Usag-1 siRNA can promote tooth regeneration in Runx2-deficient mice.
Scientific reports
Mishima S,Takahashi K,Kiso H,Murashima-Suginami A,Tokita Y,Jo JI,Uozumi R,Nambu Y,Huang B,Harada H,Komori T,Sugai M,Tabata Y,Bessho K
A-11094 was used in Immunohistochemistry-immunofluorescence to confirm the biological effectiveness of Usag-1 Stealth siRNA at rescuing arrested tooth development in Runx2-/- mice and the effectiveness of cationized gelatin as a DDS for the local administration of Stealth siRNAs to promote tooth regeneration.
Thu Jul 01 00:00:00 EDT 2021
Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids.
Cell death & disease
Lepore Signorile M,Grossi V,Di Franco S,Forte G,Disciglio V,Fasano C,Sanese P,De Marco K,Susca FC,Mangiapane LR,Nicotra A,Di Carlo G,Dituri F,Giannelli G,Ingravallo G,Canettieri G,Stassi G,Simone C
A-11094 was used in Immunocytochemistry to suggest that p38α may be targeted in CSCs to devise new personalized CRC treatment strategies.
Thu Mar 25 00:00:00 EDT 2021
On the role of p53 in the cellular response to aneuploidy.
Cell reports
Narkar A,Johnson BA,Bharne P,Zhu J,Padmanaban V,Biswas D,Fraser A,Iglesias PA,Ewald AJ,Li R
A-11094 was used in Immunocytochemistry to suggest that p53 may not act as a universal surveillance factor restricting the proliferation of aneuploid cells but instead helps directly or indirectly ensure faithful chromosome transmission likely by preventing polyploidization and influencing spindle mechanics.
Tue Mar 23 00:00:00 EDT 2021
DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis.
JCI insight
Deng J,Kang Y,Cheng CC,Li X,Dai B,Katz MH,Men T,Kim MP,Koay EA,Huang H,Brekken RA,Fleming JB
A-11094 was used in Immunocytochemistry to highlight the critical contribution of collagen I-DDR1 interaction in the formation of an immune microenvironment that promotes PDAC metastasis.
Wed Sep 08 00:00:00 EDT 2021
A Highly Selective MNK Inhibitor Rescues Deficits Associated with Fragile X Syndrome in Mice.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Shukla T,de la Peña JB,Perish JM,Ploski JE,Stumpf CR,Webster KR,Thorn CA,Campbell ZT
A-11094 was used in Immunohistochemistry to establish eFT508 as a potential means to reverse deficits associated with FXS.
Fri Jan 01 00:00:00 EST 2021
Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer.
Nature communications
Dang F,Nie L,Zhou J,Shimizu K,Chu C,Wu Z,Fassl A,Ke S,Wang Y,Zhang J,Zhang T,Tu Z,Inuzuka H,Sicinski P,Bass AJ,Wei W
A-11094 was used in Immunocytochemistry to examine the protein levels of key cell cycle related proteins involved in regulating drug sensitivity to better understand the molecular mechanisms underlying the acquisition of drug resistance in breast cancer cells.
Fri Sep 10 00:00:00 EDT 2021
Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.
Cancer cell
Chan JM,Quintanal-Villalonga Á,Gao VR,Xie Y,Allaj V,Chaudhary O,Masilionis I,Egger J,Chow A,Walle T,Mattar M,Yarlagadda DVK,Wang JL,Uddin F,Offin M,Ciampricotti M,Qeriqi B,Bahr A,de Stanchina E,Bhanot UK,Lai WV,Bott MJ,Jones DR,Ruiz A,Baine MK,Li Y,Rekhtman N,Poirier JT,Nawy T,Sen T,Mazutis L,Hollmann TJ,Pe'er D,Rudin CM
A-11094 was used in Immunohistochemistry to identify the heterogeneity of SCLC tumors and their associated microenvironments across subtypes.
Mon Nov 08 00:00:00 EST 2021
Microbiota modulate sympathetic neurons via a gut-brain circuit.
Nature
Muller PA,Schneeberger M,Matheis F,Wang P,Kerner Z,Ilanges A,Pellegrino K,Del Mármol J,Castro TBR,Furuichi M,Perkins M,Han W,Rao A,Pickard AJ,Cross JR,Honda K,de Araujo I,Mucida D
A-11094 was used in Immunohistochemistry-immunofluorescence to find that the gut microbiome modulates gut-extrinsic sympathetic neurons: microbiota depletion leads to increased expression of the neuronal transcription factor cFos, and colonization of germ-free mice with bacteria that produce short-chain fatty acids suppresses cFos expression in the gut sympathetic ganglia.
Wed Jul 01 00:00:00 EDT 2020
Microbiota modulate sympathetic neurons via a gut-brain circuit.
Nature
Muller PA,Schneeberger M,Matheis F,Wang P,Kerner Z,Ilanges A,Pellegrino K,Del Mármol J,Castro TBR,Furuichi M,Perkins M,Han W,Rao A,Pickard AJ,Cross JR,Honda K,de Araujo I,Mucida D
A-11094 was used in Immunohistochemistry-immunofluorescence to find that the gut microbiome modulates gut-extrinsic sympathetic neurons: microbiota depletion leads to increased expression of the neuronal transcription factor cFos, and colonization of germ-free mice with bacteria that produce short-chain fatty acids suppresses cFos expression in the gut sympathetic ganglia.
Wed Jul 01 00:00:00 EDT 2020
Long-Term Value Memory in the Primate Posterior Thalamus for Fast Automatic Action.
Current biology : CB
Kim HF,Griggs WS,Hikosaka O
A-11094 was used in Immunohistochemistry to suggest an SC-posterior thalamus-BG-SC subcortical loop circuit that encodes the historical value, enabling a quick automatic gaze by bypassing the visual cortex.
Mon Aug 03 00:00:00 EDT 2020
Arabidopsis DNA Replication Initiates in Intergenic, AT-Rich Open Chromatin.
Plant physiology
Wheeler E,Brooks AM,Concia L,Vera DL,Wear EE,LeBlanc C,Ramu U,Vaughn MW,Bass HW,Martienssen RA,Thompson WF,Hanley-Bowdoin L
A-11094 was used in Immunoprecipitation to show Arabidopsis DNA replication initiation occurs similarly to well-studied eukaryotic systems.
Fri May 01 00:00:00 EDT 2020
AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design.
mAbs
Sanches M,D'Angelo I,Jaramillo M,Baardsnes J,Zwaagstra J,Schrag J,Schoenhofen I,Acchione M,Lawn S,Wickman G,Weisser N,Poon DKY,Ng G,Dixit S
A-11094 was used in Flow cytometry/Cell sorting to explore the use of a human serum albumin scaffold, AlbuCORE, for the design of multispecific biologics.
Mon Jul 05 00:00:00 EDT 2021
Endophilin-A2-dependent tubular endocytosis promotes plasma membrane repair and parasite invasion.
Journal of cell science
Corrotte M,Cerasoli M,Maeda FY,Andrews NW
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
Endophilin-A2-dependent tubular endocytosis promotes plasma membrane repair and parasite invasion.
Journal of cell science
Corrotte M,Cerasoli M,Maeda FY,Andrews NW
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Tue Dec 01 00:00:00 EST 2020
Concentration of infectious SARS-CoV-2 by polyethylene glycol precipitation.
Journal of virological methods
Alexander MR,Rootes CL,van Vuren PJ,Stewart CR
A-11094 was used in an ELISA assay to underscore the utility of PEG-mediated precipitation for SARS-CoV-2 and provides a resource for a range of coronavirus research areas.
Tue Dec 01 00:00:00 EST 2020
Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway.
Cells
Majera D,Skrott Z,Chroma K,Merchut-Maya JM,Mistrik M,Bartek J
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunocytochemistry
Tue Feb 18 00:00:00 EST 2020
Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.
JCI insight
Dridi H,Liu X,Yuan Q,Reiken S,Yehia M,Sittenfeld L,Apostolou P,Buron J,Sicard P,Matecki S,Thireau J,Menuet C,Lacampagne A,Marks AR
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunohistochemistry (Frozen)
Fri Oct 02 00:00:00 EDT 2020
Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.
JCI insight
Dridi H,Liu X,Yuan Q,Reiken S,Yehia M,Sittenfeld L,Apostolou P,Buron J,Sicard P,Matecki S,Thireau J,Menuet C,Lacampagne A,Marks AR
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunohistochemistry (Frozen)
Fri Oct 02 00:00:00 EDT 2020
Protocol to Generate Senescent Cells from the Mouse Hepatic Cell Line AML12 to Study Hepatic Aging.
STAR protocols
Tripathi M,Yen PM,Singh BK
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunocytochemistry
Fri Sep 18 00:00:00 EDT 2020
Protocol to Generate Senescent Cells from the Mouse Hepatic Cell Line AML12 to Study Hepatic Aging.
STAR protocols
Tripathi M,Yen PM,Singh BK
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunocytochemistry
Fri Sep 18 00:00:00 EDT 2020
Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway.
International journal of molecular sciences
Sung NJ,Kim NH,Surh YJ,Park SA
A-11094 was used in Immunocytochemistry to suggest that GREM1 can promote lung metastasis of breast cancer cells through the STAT3-MMP13 pathway.
Thu Dec 03 00:00:00 EST 2020
Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway.
International journal of molecular sciences
Sung NJ,Kim NH,Surh YJ,Park SA
A-11094 was used in Immunocytochemistry to suggest that GREM1 can promote lung metastasis of breast cancer cells through the STAT3-MMP13 pathway.
Thu Dec 03 00:00:00 EST 2020
Doa10 is a membrane protein retrotranslocase in ER-associated protein degradation.
eLife
Schmidt CC,Vasic V,Stein A
A-11094 was used in Antibody accessibility assay to reveal how a membrane-bound retrotranslocase cooperates with the Cdc48 ATPase in membrane protein extraction.
Fri Jun 26 00:00:00 EDT 2020
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder.
Cell reports
Morishita H,Kanda Y,Kaizuka T,Chino H,Nakao K,Miki Y,Taketomi Y,Guan JL,Murakami M,Aiba A,Mizushima N
A-11094 was used in Immunohistochemistry (Paraffin) to demonstrate an evolutionarily conserved role of autophagy in lamellar body maturation.
Tue Dec 08 00:00:00 EST 2020
Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder.
Cell reports
Morishita H,Kanda Y,Kaizuka T,Chino H,Nakao K,Miki Y,Taketomi Y,Guan JL,Murakami M,Aiba A,Mizushima N
A-11094 was used in Immunohistochemistry (Paraffin) to demonstrate an evolutionarily conserved role of autophagy in lamellar body maturation.
Tue Dec 08 00:00:00 EST 2020
Injectable, photoresponsive hydrogels for delivering neuroprotective proteins enabled by metal-directed protein assembly.
Science advances
Jiang B,Liu X,Yang C,Yang Z,Luo J,Kou S,Liu K,Sun F
A-11094 was used in Immunohistochemistry to present a simple approach for creating injectable, photoresponsive hydrogels via metal-directed assembly of His6-tagged proteins.
Thu Oct 01 00:00:00 EDT 2020
Injectable, photoresponsive hydrogels for delivering neuroprotective proteins enabled by metal-directed protein assembly.
Science advances
Jiang B,Liu X,Yang C,Yang Z,Luo J,Kou S,Liu K,Sun F
A-11094 was used in Immunohistochemistry to present a simple approach for creating injectable, photoresponsive hydrogels via metal-directed assembly of His6-tagged proteins.
Thu Oct 01 00:00:00 EDT 2020
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Nature communications
Horstmann JA,Lunelli M,Cazzola H,Heidemann J,Kühne C,Steffen P,Szefs S,Rossi C,Lokareddy RK,Wang C,Lemaire L,Hughes KT,Uetrecht C,Schlüter H,Grassl GA,Stradal TEB,Rossez Y,Kolbe M,Erhardt M
A-11094 was used in Immunocytochemistry-immunoflourescence to demonstrate that FliB-dependent methylation of flagella might represent a general mechanism facilitating adhesion to hydrophobic host cell surfaces in a broad range of bacterial species.
Fri Apr 24 00:00:00 EDT 2020
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion.
Nature communications
Horstmann JA,Lunelli M,Cazzola H,Heidemann J,Kühne C,Steffen P,Szefs S,Rossi C,Lokareddy RK,Wang C,Lemaire L,Hughes KT,Uetrecht C,Schlüter H,Grassl GA,Stradal TEB,Rossez Y,Kolbe M,Erhardt M
A-11094 was used in Immunocytochemistry-immunoflourescence to demonstrate that FliB-dependent methylation of flagella might represent a general mechanism facilitating adhesion to hydrophobic host cell surfaces in a broad range of bacterial species.
Fri Apr 24 00:00:00 EDT 2020
Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties.
PloS one
Anchoori RK,Tan M,Tseng SH,Peng S,Soong RS,Algethami A,Foran P,Das S,Wang C,Wang TL,Liang H,Hung CF,Roden RBS
A-11094 was used in Immunocytochemistry to analyse the structure and function of anti-tumorigenic inhibitors targeted towards ubiquitin receptor RPN13 within the proteasome's 19S regulatory particle.
Thu Apr 16 00:00:00 EDT 2020
Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots.
PLoS genetics
Wear EE,Song J,Zynda GJ,Mickelson-Young L,LeBlanc C,Lee TJ,Deppong DO,Allen GC,Martienssen RA,Vaughn MW,Hanley-Bowdoin L,Thompson WF
A-11094 was used in Chromatin immunoprecipitation to investigate DNA replication programs in these two types of cell cycles, we pulse labeled intact root tips of maize with 5-ethynyl-2'-deoxyuridine and used flow sorting of nuclei to examine DNA replication timing during the transition from a mitotic cycle to an endocycle.
Thu Oct 01 00:00:00 EDT 2020
Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection.
Science (New York, N.Y.)
Sweere JM,Van Belleghem JD,Ishak H,Bach MS,Popescu M,Sunkari V,Kaber G,Manasherob R,Suh GA,Cao X,de Vries CR,Lam DN,Marshall PL,Birukova M,Katznelson E,Lazzareschi DV,Balaji S,Keswani SG,Hawn TR,Secor PR,Bollyky PL
A-11094 was used in Immunocytochemistry-immunoflourescence to establish pathogenic roles for bacteriophage in bacterial infections: by initiating an antiviral response in the host, bacteriophage are able to suppress bacterial clearance.
Fri Mar 29 00:00:00 EDT 2019
A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly.
Molecular cell
Maori E,Navarro IC,Boncristiani H,Seilly DJ,Rudolph KLM,Sapetschnig A,Lin CC,Ladbury JE,Evans JD,Heeney JL,Miska EA
A-11094 was used in Immunohistochemistry to determine the mechanism by which royal honeybee jelly facilitates RNA transfer between honeybees.
Thu May 02 00:00:00 EDT 2019
NDRG1 facilitates the replication and persistence of Kaposi's sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA.
PLoS pathogens
Zhang F,Liang D,Lin X,Zou Z,Sun R,Wang X,Liang X,Kaye KM,Lan K
A-11094 was used in Immunohistochemistry-immunofluorescence to elucidate that N-Myc downstream regulated gene 1 was highly upregulated by Kaposi's sarcoma herpesvirus in proliferating cells.
Fri Feb 01 00:00:00 EST 2019
Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation.
mAbs
Hatterer E,Barba L,Noraz N,Daubeuf B,Aubry-Lachainaye JP,von der Weid B,Richard F,Kosco-Vilbois M,Ferlin W,Shang L,Buatois V
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Mon Jul 29 00:00:00 EDT 2019
Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation.
mAbs
Hatterer E,Barba L,Noraz N,Daubeuf B,Aubry-Lachainaye JP,von der Weid B,Richard F,Kosco-Vilbois M,Ferlin W,Shang L,Buatois V
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Mon Jul 29 00:00:00 EDT 2019
Neuronal Membrane Disruption Occurs Late Following Diffuse Brain Trauma in Rats and Involves a Subpopulation of NeuN Negative Cortical Neurons.
Frontiers in neurology
Hernandez ML,Chatlos T,Gorse KM,Lafrenaye AD
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunohistochemistry
Tue Oct 06 00:00:00 EDT 2020
Neuronal connections of direct and indirect pathways for stable value memory in caudal basal ganglia.
The European journal of neuroscience
Amita H,Kim HF,Smith MK,Gopal A,Hikosaka O
A-11094 was used in Immunohistochemistry-immunofluorescence to study the neuronal connections of direct and indirect pathways for stable value memory in caudal basal ganglia.
Fri Mar 01 00:00:00 EST 2019
Long-label-retaining mammary epithelial cells are created early in ductal development and distributed throughout the branching ducts.
Mechanisms of development
Ragle LE,Bruno RD,Boulanger CA,Smith GH
A-11094 was used in Immunocytochemistry-immunoflourescence to show that LREC may represent long-lived progenitor cells that are responsible for mammary gland homeostasis.
Tue Oct 01 00:00:00 EDT 2019
Critical Size Limit of Biodegradable Nanoparticles for Enhanced Lymph Node Trafficking and Paracortex Penetration.
Nano research
Howard GP,Verma G,Ke X,Thayer WM,Hamerly T,Baxter VK,Lee JE,Dinglasan RR,Mao HQ
A-11094 was used in Immunohistochemistry to show that 20-nm NPs drain rapidly across proximal and distal LNs following subcutaneous inoculation in mice and are retained in LNs more effectively than NPs with a number average diameter of 40-nm.
Mon Apr 01 00:00:00 EDT 2019
Visualizing the cellular route of entry of a cystine-knot peptide with Xfect transfection reagent by electron microscopy.
Scientific reports
Gao X,De Mazière A,Iaea DB,Arthur CP,Klumperman J,Ciferri C,Hannoush RN
A-11094 was used in Immuno-electron microscopy to determine the cellular uptake mechanisms of cystine knot peptides.
Mon May 06 00:00:00 EDT 2019
Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation.
Nature communications
Czechowicz A,Palchaudhuri R,Scheck A,Hu Y,Hoggatt J,Saez B,Pang WW,Mansour MK,Tate TA,Chan YY,Walck E,Wernig G,Shizuru JA,Winau F,Scadden DT,Rossi DJ
A-11094 was used in Flow cytometry/Cell sorting to study the use of a CD117-antibody-drug-conjugate to deplete host haematopoietic stem cells prior to haematopoietic stem cell transplantation.
Wed Feb 06 00:00:00 EST 2019
Ouabain Enhances Cell-Cell Adhesion Mediated by β1 Subunits of the Na+,K+-ATPase in CHO Fibroblasts.
International journal of molecular sciences
Vilchis-Nestor CA,Roldán ML,Leonardi A,Navea JG,Padilla-Benavides T,Shoshani L
A-11094 was used in Western Blotting to suggest that the Β1 subunit adhesion is modulated by the expression levels of the Na+,K+-ATPase at the plasma membrane, which is regulated by ouabain.
Mon Apr 29 00:00:00 EDT 2019
Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia.
Cell reports
Bernier LP,Bohlen CJ,York EM,Choi HB,Kamyabi A,Dissing-Olesen L,Hefendehl JK,Collins HY,Stevens B,Barres BA,MacVicar BA
A-11094 was used in Immunohistochemistry-immunofluorescence to study how shifting intracellular cAMP levels controls the polarity of microglial responses to changes in brain homeostasis and alters the scale of immunosurveillance.
Tue Jun 04 00:00:00 EDT 2019
Hypoxia Triggers SENP1 (Sentrin-Specific Protease 1) Modulation of KLF15 (Kruppel-Like Factor 15) and Transcriptional Regulation of Arg2 (Arginase 2) in Pulmonary Endothelium.
Arteriosclerosis, thrombosis, and vascular biology
Pandey D,Nomura Y,Rossberg MC,Hori D,Bhatta A,Keceli G,Leucker T,Santhanam L,Shimoda LA,Berkowitz D,Romer L
A-11094 was used in Immunocytochemistry-immunoflourescence to test the hypothesis that KLF15 is a critical regulator of hypoxia-induced Arg2 (arginase 2) transcription in human pulmonary microvascular endothelial cells (HPMEC).
Sun Apr 01 00:00:00 EDT 2018
Genome-Wide Analysis of the Arabidopsis Replication Timing Program.
Plant physiology
Concia L,Brooks AM,Wheeler E,Zynda GJ,Wear EE,LeBlanc C,Song J,Lee TJ,Pascuzzi PE,Martienssen RA,Vaughn MW,Thompson WF,Hanley-Bowdoin L
A-11094 was used in Immunoprecipitation to show how temporal order of DNA replication within the early/mid compartment may be modulated largely by chromatin accessibility.
Thu Mar 01 00:00:00 EST 2018
Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor.
PLoS pathogens
Stichling N,Suomalainen M,Flatt JW,Schmid M,Pacesa M,Hemmi S,Jungraithmayr W,Maler MD,Freudenberg MA,Plückthun A,May T,Köster M,Fejer G,Greber UF
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Miscellaneous
Thu Mar 01 00:00:00 EST 2018
JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Morel C,Sherrin T,Kennedy NJ,Forest KH,Avcioglu Barutcu S,Robles M,Carpenter-Hyland E,Alfulaij N,Standen CL,Nichols RA,Benveniste M,Davis RJ,Todorovic C
A-11094 was used in Immunocytochemistry-immunoflourescence to identify c-Jun N-terminal kinase (JNK)-interacting protein 1-mediated JNK activation as a novel molecular pathway that negatively regulates NMDAR-dependent synaptic plasticity and memory.
Wed Apr 11 00:00:00 EDT 2018
The Autism Protein Ube3A/E6AP Remodels Neuronal Dendritic Arborization via Caspase-Dependent Microtubule Destabilization.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Khatri N,Gilbert JP,Huo Y,Sharaflari R,Nee M,Qiao H,Man HY
A-11094 was used in Immunocytochemistry-immunoflourescence to study the mechanism by which Ube3A/E6AP remodels neuronal dendritic arborisation.
Wed Jan 10 00:00:00 EST 2018
Coherent Activity between the Prelimbic and Auditory Cortex in the Slow-Gamma Band Underlies Fear Discrimination.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Concina G,Cambiaghi M,Renna A,Sacchetti B
A-11094 was used in Immunohistochemistry-immunofluorescence to show that in male rats that can differentiate between a new tone and a threatening one, the selective optogenetic inhibition of Te1 axon terminals into the prelimbic cortex shifted discrimination to fear generalization.
Wed Sep 26 00:00:00 EDT 2018
TRPV4 heats up ANO1-dependent exocrine gland fluid secretion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Derouiche S,Takayama Y,Murakami M,Tominaga M
A-11094 was used in Immunocytochemistry to suggest that TRPV4 interacts with IP3receptors and ANO1 to regulate the muscarinic pathway that mediates salivation and lacrimation.
Sun Apr 01 00:00:00 EDT 2018
Arcuate nucleus and lateral hypothalamic CART neurons in the mouse brain exert opposing effects on energy expenditure.
eLife
Farzi A,Lau J,Ip CK,Qi Y,Shi YC,Zhang L,Tasan R,Sperk G,Herzog H
A-11094 was used in Immunohistochemistry-immunofluorescence to demonstrate the anorexigenic but anabolic effects of cocaine- and amphetamine-regulated transcript upon Arc neuron activation, and the orexigenic but catabolic effects upon lateral hypothalamus-neuron activation.
Tue Aug 21 00:00:00 EDT 2018
Cell metabolism regulates integrin mechanosensing via an SLC3A2-dependent sphingolipid biosynthesis pathway.
Nature communications
Boulter E,Estrach S,Tissot FS,Hennrich ML,Tosello L,Cailleteau L,de la Ballina LR,Pisano S,Gavin AC,Féral CC
A-11094 was used in Immunohistochemistry-Immunofluorescence to show that cellular metabolism can regulate integrin rigidity-sensing via the sphingolipid metabolic pathway controlled by the amino acid transporter and integrin coreceptor CD98hc.
Mon Nov 19 00:00:00 EST 2018
Inter- and intra-specific differences in muscarinic acetylcholine receptor expression in the neural pathways for vocal learning in songbirds.
The Journal of comparative neurology
Asogwa NC,Mori C,Sánchez-Valpuesta M,Hayase S,Wada K
A-11094 was used in Immunohistochemistry-immunofluorescence to suggest that mAChRs play an underappreciated role in the development of species and individual differences in song patterns by modulating the excitability of HVC neurons, providing a potential insight into the gating of auditory responses in HVC neurons.
Sat Dec 01 00:00:00 EST 2018
Expression patterns of ion channels and structural proteins in a multimodal cell type of the avian optic tectum.
The Journal of comparative neurology
Lischka K,Ladel S,Luksch H,Weigel S
A-11094 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry to present immunohistochemical data of structural proteins (NF200, Ankyrin G, and Myelin) and ion channels (Pan-Nav, Nav 1.6, and Kv 3.1b).
Thu Feb 15 00:00:00 EST 2018
Genomic Analysis of the DNA Replication Timing Program during Mitotic S Phase in Maize (Zea mays) Root Tips.
The Plant cell
Wear EE,Song J,Zynda GJ,LeBlanc C,Lee TJ,Mickelson-Young L,Concia L,Mulvaney P,Szymanski ES,Allen GC,Martienssen RA,Vaughn MW,Hanley-Bowdoin L,Thompson WF
A-11094 was used in Immunoprecipitation to demonstrate that the centromere core replicates in mid S, before heavily compacted classical heterochromatin, including pericentromeres and knobs, which replicate during late S phase.
Fri Sep 01 00:00:00 EDT 2017
New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.
The Journal of cell biology
Wood LA,Larocque G,Clarke NI,Sarkar S,Royle SJ
A-11094 was used in Immunocytochemistry-immunoflourescence to describe a series of genetically encoded reporters that allow the initiation of clathrin-mediated endocytosis on demand.
Mon Dec 04 00:00:00 EST 2017
Male hormones activate EphA2 to facilitate Kaposi's sarcoma-associated herpesvirus infection: Implications for gender disparity in Kaposi's sarcoma.
PLoS pathogens
Wang X,Zou Z,Deng Z,Liang D,Zhou X,Sun R,Lan K
A-11094 was used in Immunocytochemistry to show that knockdown of androgen receptor expression or pre-treatment with 5α-dihydrotestosterone, causes considerable Kaposi's sarcoma-associated herpesvirus infection dysregulation.
Fri Sep 01 00:00:00 EDT 2017
Differential phosphorylation signals control endocytosis of GPR15.
Molecular biology of the cell
Okamoto Y,Shikano S
A-11094 was used in Flow Cytometry to demonstrate that phosphorylation signals may differentially control cell surface density of GPR15 through endocytosis.
Tue Aug 15 00:00:00 EDT 2017
Novel ecto-tagged integrins reveal their trafficking in live cells.
Nature communications
Huet-Calderwood C,Rivera-Molina F,Iwamoto DV,Kromann EB,Toomre D,Calderwood DA
A-11094 was used in Immunocytochemistry-immunoflourescence to develop Β1 integrins carrying traceable tags in the extracellular domain; a pH-sensitive pHlourin tag or a HaloTag to facilitate dye attachment.
Mon Sep 18 00:00:00 EDT 2017
Correlative light and electron microscopy reveals discrepancy between gold and fluorescence labelling.
Journal of microscopy
VAN Elsland DM,Bos E,Pawlak JB,Overkleeft HS,Koster AJ,VAN Kasteren SI
A-11094 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry to reveal and characterize the existence of inherent discrepancies between the fluorescence signal and the distribution of gold particles in particular in the case of membrane-associated antigens.
Fri Sep 01 00:00:00 EDT 2017
Chemical labelling for visualizing native AMPA receptors in live neurons.
Nature communications
Wakayama S,Kiyonaka S,Arai I,Kakegawa W,Matsuda S,Ibata K,Nemoto YL,Kusumi A,Yuzaki M,Hamachi I
A-11094 was used in Immunocytochemistry-immunoflourescence to report a powerful method for visualizing native α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors.
Fri Apr 07 00:00:00 EDT 2017
Carbon nanotubes exhibit fibrillar pharmacology in primates.
PloS one
Alidori S,Thorek DLJ,Beattie BJ,Ulmert D,Almeida BA,Monette S,Scheinberg DA,McDevitt MR
A-11094 was used in Immunohistochemistry on paraffin embedded tissues-immunofluorescence to provide a multi-organ evaluation of the distribution, uptake and processing of ammonium-functionalised carbon nanotubes in nonhuman primates.
Thu Oct 26 00:00:00 EDT 2017
Targeted fibrillar nanocarbon RNAi treatment of acute kidney injury.
Science translational medicine
Alidori S,Akhavein N,Thorek DL,Behling K,Romin Y,Queen D,Beattie BJ,Manova-Todorova K,Bergkvist M,Scheinberg DA,McDevitt MR
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunofluorescence
Wed Mar 23 00:00:00 EDT 2016
ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.
PloS one
Ray A,Blevins C,Wani G,Wani AA
A11094 was used in western blot to examine ultraviolet radiation-induced ATR and ATM recruitment during G1 and S phases
Mon Jul 31 00:00:00 EDT 2017
Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos.
Journal of visualized experiments : JoVE
Lee JH,Cho YI,Choi SS,Kim HW,Min CK,Lee SJ
A-11094 was used in immunohistochemistry to investigate early cell fate determinants in preimplantation mouse embryos using a loss- and gain-of-function approach
Mon Jun 06 00:00:00 EDT 2016
Alp7/TACC-Alp14/TOG generates long-lived, fast-growing MTs by an unconventional mechanism.
Scientific reports
Hussmann F,Drummond DR,Peet DR,Martin DS,Cross RA
A-11094 was used in other to elucidate how Alp14 regulates microtubule growth
Thu Feb 11 00:00:00 EST 2016
The X-Linked Autism Protein KIAA2022/KIDLIA Regulates Neurite Outgrowth via N-Cadherin and δ-Catenin Signaling.
eNeuro
Gilbert J,Man HY
A11094 was used in western blot to propose a role for KIDLIA in neurodevelopment and autism
Tue Oct 31 00:00:00 EDT 2017
The Apical Localization of Na+, K+-ATPase in Cultured Human Retinal Pigment Epithelial Cells Depends on Expression of the β2 Subunit.
Frontiers in physiology
Lobato-Álvarez JA,Roldán ML,López-Murillo TD,González-Ramírez R,Bonilla-Delgado J,Shoshani L
A11094 was used in immunocytochemistry to show that apical polarization of the sodium, potassium-ATPase in retinal pigment epithelium cells depends on the expression of the beta2 subunit
Wed Sep 30 00:00:00 EDT 2020
Chromothripsis-like chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system.
Oncotarget
Morishita M,Muramatsu T,Suto Y,Hirai M,Konishi T,Hayashi S,Shigemizu D,Tsunoda T,Moriyama K,Inazawa J
A-11094 was used in Immunocytochemistry-immunoflourescence to identify the mechanism underlying the generation of chromothripsis.
Tue Mar 01 00:00:00 EST 2016
Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies.
The Journal of biological chemistry
Shcherbatko A,Foletti D,Poulsen K,Strop P,Zhu G,Hasa-Moreno A,Melton Witt J,Loo C,Krimm S,Pios A,Yu J,Brown C,Lee JK,Stroud R,Rajpal A,Shelton D
A-11094 was used in immunocytochemistry to assess modulation of P2X2/3 and P2X3 receptors via monoclonal antibodies
Fri Jun 03 00:00:00 EDT 2016
Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage.
The Journal of clinical investigation
Yougbaré I,Lang S,Yang H,Chen P,Zhao X,Tai WS,Zdravic D,Vadasz B,Li C,Piran S,Marshall A,Zhu G,Tiller H,Killie MK,Boyd S,Leong-Poi H,Wen XY,Skogen B,Adamson SL,Freedman J,Ni H
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunofluorescence
Wed Apr 01 00:00:00 EDT 2015
Proximity-dependent initiation of hybridization chain reaction.
Nature communications
Koos B,Cane G,Grannas K,Löf L,Arngården L,Heldin J,Clausson CM,Klaesson A,Hirvonen MK,de Oliveira FM,Talibov VO,Pham NT,Auer M,Danielson UH,Haybaeck J,Kamali-Moghaddam M,Söderberg O
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2015
Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments.
The Journal of cell biology
Jones SL,Korobova F,Svitkina T
A-11094 was used in immunocytochemistry to assess the axon initial segment cytoskeleton architecture in mature and developing hippocampal neurons
Mon Apr 14 00:00:00 EDT 2014
Specialization of oleosins in oil body dynamics during seed development in Arabidopsis seeds.
Plant physiology
Miquel M,Trigui G,d'Andréa S,Kelemen Z,Baud S,Berger A,Deruyffelaere C,Trubuil A,Lepiniec L,Dubreucq B
A-11094 was used in immunohistochemistry to evaluate the dynamics of oil bodies in living Arabidopsis thaliana embryos at different stages of development
Tue Apr 01 00:00:00 EDT 2014
The level of HER2 expression is a predictor of antibody-HER2 trafficking behavior in cancer cells.
mAbs
Ram S,Kim D,Ober RJ,Ward ES
A-11094 was used in Immunocytochemistry-immunoflourescence to demonstrate that HER2 expression levels, rather than cell origin, is a determinant of subcellular trafficking properties.
Mon Aug 24 00:00:00 EDT 2015
DropArray™, a wall-less 96-well plate for uptake and immunofluorescence microscopy, confirms CD22 recycles.
Traffic (Copenhagen, Denmark)
Ingle GS,Scales SJ
A-11094 was used in Flow cytometry/Cell sorting to examine the time-course of trafficking of five different anti-CD22 antibodies in eight B-cell lines representing four B-cell cancer types.
Sat Mar 01 00:00:00 EST 2014
GABAergic neurons in the ventral tegmental area receive dual GABA/enkephalin-mediated inhibitory inputs from the bed nucleus of the stria terminalis.
The European journal of neuroscience
Kudo T,Konno K,Uchigashima M,Yanagawa Y,Sora I,Minami M,Watanabe M
A-11094 was used in immunohistochemistry to study the neural transmission to GABAergic neurons in the ventral tegmental area from the bed nucleus of the stria terminalis.
Sun Jun 01 00:00:00 EDT 2014
The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density.
Molecular biology of the cell
Termini CM,Cotter ML,Marjon KD,Buranda T,Lidke KA,Gillette JM
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density.
Molecular biology of the cell
Termini CM,Cotter ML,Marjon KD,Buranda T,Lidke KA,Gillette JM
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Flow Cytometry
Thu May 01 00:00:00 EDT 2014
Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.
Virology
Yamasaki T,Baron GS,Suzuki A,Hasebe R,Horiuchi M
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Western Blot
Sat Feb 01 00:00:00 EST 2014
Cortical innervation of the hypoglossal nucleus in the non-human primate (Macaca mulatta).
The Journal of comparative neurology
Morecraft RJ,Stilwell-Morecraft KS,Solon-Cline KM,Ge J,Darling WG
A-11094 was used in immunohistochemistry to study the corticobulbar projection to the hypoglossal nucleus in the non-human primate.
Wed Oct 15 00:00:00 EDT 2014
Most human proteins made in both nucleus and cytoplasm turn over within minutes.
PloS one
Baboo S,Bhushan B,Jiang H,Grovenor CR,Pierre P,Davis BG,Cook PR
A-11094 was used in immunocytochemistry to study the minues of a turn over rate of human proteins in the nucleus and cytoplasm
Wed Oct 07 00:00:00 EDT 2015
A human genome-wide screen for regulators of clathrin-coated vesicle formation reveals an unexpected role for the V-ATPase.
Nature cell biology
Kozik P,Hodson NA,Sahlender DA,Simecek N,Soromani C,Wu J,Collinson LM,Robinson MS
A-11094 was used in blocking or activating experiment to identify factors that regulate clathrin-mediated endocytosis
Tue Jan 01 00:00:00 EST 2013
Nanoparticles that sense thrombin activity as synthetic urinary biomarkers of thrombosis.
ACS nano
Lin KY,Kwong GA,Warren AD,Wood DK,Bhatia SN
A-11094 was used in ELISA to describe a method to detect thrombi in living animals
Tue Oct 22 00:00:00 EDT 2013
Caveolae internalization repairs wounded cells and muscle fibers.
eLife
Corrotte M,Almeida PE,Tam C,Castro-Gomes T,Fernandes MC,Millis BA,Cortez M,Miller H,Song W,Maugel TK,Andrews NW
A-11094 was used in flow cytometry to assess repair of wounded cells and muscle fibers due to caveolae internalization
Tue Sep 17 00:00:00 EDT 2013
The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Aizawa H,Yanagihara S,Kobayashi M,Niisato K,Takekawa T,Harukuni R,McHugh TJ,Fukai T,Isomura Y,Okamoto H
A-11094 was used in Immunohistochemistry-immunofluorescence to examine the effects of rat lateral habenula lesions on the hippocampal oscillatory activity associated with the transition of brain states.
Wed May 15 00:00:00 EDT 2013
Nitric oxide synthesis and cGMP production is important for neurite growth and synapse remodeling after axotomy.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Cooke RM,Mistry R,Challiss RA,Straub VA
A-11094 was used in immunocytochemistry to examine the role of endogenous nitric oxide signaling in neuronal growth and synaptic remodeling after nerve injury
Wed Mar 27 00:00:00 EDT 2013
Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models.
Molecular cancer therapeutics
Herter S,Herting F,Mundigl O,Waldhauer I,Weinzierl T,Fauti T,Muth G,Ziegler-Landesberger D,Van Puijenbroek E,Lang S,Duong MN,Reslan L,Gerdes CA,Friess T,Baer U,Burtscher H,Weidner M,Dumontet C,Umana P,Niederfellner G,Bacac M,Klein C
A-11094 was used in blocking or activating experiment to compare rituximab and ofatumumab in vitro and in xenograft models and preclinical activity of the type II CD20 antibody GA101 (obinutuzumab)
Tue Oct 01 00:00:00 EDT 2013
Inhibitors of PI(4,5)P2 synthesis reveal dynamic regulation of IgE receptor signaling by phosphoinositides in RBL mast cells.
Molecular pharmacology
Santos Mde S,Naal RM,Baird B,Holowka D
A-11094 was used in immunocytochemistry to study how PI4P generated by PI4-kinase IIIalpha regulates IgE receptors
Mon Apr 01 00:00:00 EDT 2013
The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments.
Molecular biology of the cell
Cortese K,Howes MT,Lundmark R,Tagliatti E,Bagnato P,Petrelli A,Bono M,McMahon HT,Parton RG,Tacchetti C
A-11094 was used in Immunocytochemistry to study the entry route and postendocytic sorting of ErbB2 upon geldanamycin stimulation.
Tue Jan 01 00:00:00 EST 2013
The ability of TNPO3-depleted cells to inhibit HIV-1 infection requires CPSF6.
Retrovirology
Fricke T,Valle-Casuso JC,White TE,Brandariz-Nuñez A,Bosche WJ,Reszka N,Gorelick R,Diaz-Griffero F
A-11094 was used in Immunocytochemistry-immunoflourescence to demonstrate that overexpression of a cytosolic full-length CPSF6 blocks HIV-1 infection at the nuclear import step.
Fri Apr 26 00:00:00 EDT 2013
Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage.
PloS one
Smith ER,Hanssen E,McMahon LP,Holt SG
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Miscellaneous
Tue Oct 22 00:00:00 EDT 2013
Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage.
PloS one
Smith ER,Hanssen E,McMahon LP,Holt SG
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Miscellaneous
Tue Oct 22 00:00:00 EDT 2013
A Y-linked anti-Müllerian hormone duplication takes over a critical role in sex determination.
Proceedings of the National Academy of Sciences of the United States of America
Hattori RS,Murai Y,Oura M,Masuda S,Majhi SK,Sakamoto T,Fernandino JI,Somoza GM,Yokota M,Strüssmann CA
A-11094 was used in immunohistochemistry to report the role of a male-specific, duplicated copy of the anti-Mullerian hormone in the testicular development of Patagonian pejerrey
Tue Feb 21 00:00:00 EST 2012
Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Lafrenaye AD,McGinn MJ,Povlishock JT
A-11094 was used in Immunohistochemistry-immunofluorescence to investigate the specific neuronal somatic and axonal damaging consequences of elevated intercranial pressure, independent of its impact on cerebral perfusion pressure.
Mon Oct 01 00:00:00 EDT 2012
Three types of neurochemical projection from the bed nucleus of the stria terminalis to the ventral tegmental area in adult mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kudo T,Uchigashima M,Miyazaki T,Konno K,Yamasaki M,Yanagawa Y,Minami M,Watanabe M
A-11094 was used in immunocytochemistry to investigate the neurochemical composition of ventral tegmental area-projecting bed nucleus of the stria terminalis neurons and their outputs to the ventral tegmental area in adult mouse brains
Wed Dec 12 00:00:00 EST 2012
Hippocampal CA3 and CA2 have distinct bilateral innervation patterns to CA1 in rodents.
The European journal of neuroscience
Shinohara Y,Hosoya A,Yahagi K,Ferecskó AS,Yaguchi K,Sík A,Itakura M,Takahashi M,Hirase H
A-11094 was used in Immunohistochemistry to demonstrate that the primary intrahippocampal target of CA2 pyramidal cells is the ipsilateral CA1 stratum oriens, in contrast to CA3 cells which project more diversely to bilateral CA1 regions.
Thu Mar 01 00:00:00 EST 2012
Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation.
The Journal of biological chemistry
Mao Y,Shang Y,Pham VC,Ernst JA,Lill JR,Scales SJ,Zha J
A-11094 was used in flow cytometry to investigate ubiquitination of insulin-like growth factor I receptor
Fri Dec 02 00:00:00 EST 2011
Preparation of dual-color polarity-marked fluorescent microtubule seeds.
Methods in molecular biology (Clifton, N.J.)
Katsuki M,Muto E,Cross RA
A-11094 was used in In vitro experiments to create functional nucleation centers for the growth of dynamic microtubules.
Mon Nov 28 00:00:00 EST 2011
Convergent potency of internalized gelonin immunotoxins across varied cell lines, antigens, and targeting moieties.
The Journal of biological chemistry
Pirie CM,Hackel BJ,Rosenblum MG,Wittrup KD
A-11094 was used in immunocytochemistry to create and characterize novel gelonin immunotoxins
Fri Feb 11 00:00:00 EST 2011
Systems survey of endocytosis by multiparametric image analysis.
Nature
Collinet C,Stöter M,Bradshaw CR,Samusik N,Rink JC,Kenski D,Habermann B,Buchholz F,Henschel R,Mueller MS,Nagel WE,Fava E,Kalaidzidis Y,Zerial M
A-11094 was used in immunocytochemistry to report a new strategy to phenotypically profile the human genome with respect to transferrin and epidermal growth factor endocytosis
Thu Mar 11 00:00:00 EST 2010
A screen for endocytic motifs.
Traffic (Copenhagen, Denmark)
Kozik P,Francis RW,Seaman MN,Robinson MS
A-11094 was used in flow cytometry to identify endocytic motifs through a new screen
Tue Jun 01 00:00:00 EDT 2010
Isolation of a highly myogenic CD34-negative subset of human skeletal muscle cells free of adipogenic potential.
Stem cells (Dayton, Ohio)
Pisani DF,Dechesne CA,Sacconi S,Delplace S,Belmonte N,Cochet O,Clement N,Wdziekonski B,Villageois AP,Butori C,Bagnis C,Di Santo JP,Kurzenne JY,Desnuelle C,Dani C
A-11094 was used in Immunocytochemistry-immunoflourescence to demonstrate that muscle-derived cells constitute a heterogeneous population of cells with various differentiation potentials.
Thu Apr 01 00:00:00 EDT 2010
Persistent cAMP-signals triggered by internalized G-protein-coupled receptors.
PLoS biology
Calebiro D,Nikolaev VO,Gagliani MC,de Filippis T,Dees C,Tacchetti C,Persani L,Lohse MJ
A-11094 was used to study the trigger by internalized G-protein-coupled receptors due to persistent cAMP-signals
Sat Aug 01 00:00:00 EDT 2009
Following the fate in vivo of COPI vesicles generated in vitro.
Traffic (Copenhagen, Denmark)
Rutz C,Satoh A,Ronchi P,Brügger B,Warren G,Wieland FT
A-11094 was used in Immunohistochemistry-immunofluorescence to describe a method that should address several open questions about the fate and function of COPI vesicles in vivo.
Sat Aug 01 00:00:00 EDT 2009
Mal3 masks catastrophe events in Schizosaccharomyces pombe microtubules by inhibiting shrinkage and promoting rescue.
The Journal of biological chemistry
Katsuki M,Drummond DR,Osei M,Cross RA
A-11094 was used in immunocytochemistry to elucidate how Mal3 influences microtubule dynamics
Fri Oct 23 00:00:00 EDT 2009
DNA cross-linking, double-strand breaks, and apoptosis in corneal endothelial cells after a single exposure to mitomycin C.
Investigative ophthalmology & visual science
Roh DS,Cook AL,Rhee SS,Joshi A,Kowalski R,Dhaliwal DK,Funderburgh JL
A-11094 was used in Immunocytochemistry to investigate the cellular effects of mitomycin C treatment on corneal endothelial cells at clinically relevant applications and dosages.
Sat Nov 01 00:00:00 EDT 2008
Association of brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2) with recycling endosomes during transferrin uptake.
Proceedings of the National Academy of Sciences of the United States of America
Shen X,Xu KF,Fan Q,Pacheco-Rodriguez G,Moss J,Vaughan M
Published figure using Alexa Fluor 488 polyclonal antibody (Product # A-11094) in Immunocytochemistry
Tue Feb 21 00:00:00 EST 2006
WNK1 kinase isoform switch regulates renal potassium excretion.
Proceedings of the National Academy of Sciences of the United States of America
Wade JB,Fang L,Liu J,Li D,Yang CL,Subramanya AR,Maouyo D,Mason A,Ellison DH,Welling PA
A-11094 was used in immunocytochemistry to study regulation of renal potassium excretion by a WNK1 kinase isoform switch
Tue May 30 00:00:00 EDT 2006
Role for centromeric heterochromatin and PML nuclear bodies in the cellular response to foreign DNA.
Molecular and cellular biology
Bishop CL,Ramalho M,Nadkarni N,May Kong W,Higgins CF,Krauzewicz N
A-11094 was used in immunocytochemistry to report a role for nuclear spatial positioning in regulating episomal transgenes that are delivered by virus-like particles
Sat Apr 01 00:00:00 EST 2006
Use of anti-fluorophore antibody to achieve high-sensitivity immunolocalizations of transporters and ion channels.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Coleman RA,Liu J,Wade JB
A-11094 was used in immunohistochemistry to develop methods that allow highly sensitive immunolocalizations in tissue while preserving cell fine structure through traditional fixation and epoxy embedding
Sat Jul 01 00:00:00 EDT 2006
A TAT-streptavidin fusion protein directs uptake of biotinylated cargo into mammalian cells.
Protein engineering, design & selection : PEDS
Albarran B,To R,Stayton PS
A-11094 was used in flow cytometry to assess the direct uptake of biotinylated cargo into mammalian cells by a TAT-streptavidin fusion protein
Tue Mar 01 00:00:00 EST 2005
A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
The Journal of biological chemistry
Raja SM,Metkar SS,Höning S,Wang B,Russin WA,Pipalia NH,Menaa C,Belting M,Cao X,Dressel R,Froelich CJ
A-11094 was used in flow cytometry to analyze electrostatic exchange from serglycin to target by granzyme B as a novel mechanism for protein delivery
Fri May 27 00:00:00 EDT 2005
