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Product Details
PA5-118146
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human ALIX/PDCD6IP fragment
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2902746
Target Information
Apoptotic linked-gene-product 2 (ALG-2) interacting protein X (ALIX) is a conserved adaptor protein which is ubiquitously expressed. Alix was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALG-2 interacting protein 1; ALG-2-interacting protein 1; ALG-2-interacting protein X; apoptosis-linked gene 2-interacting protein X; dopamine receptor interacting protein 4; Hp95; MGC17003; PDCD6-interacting protein; Programmed cell death 6-interacting protein
Gene Aliases: AIP1; ALIX; DRIP4; HP95; KIAA1375; PDCD6IP
UniProt ID: (Human) Q8WUM4
Entrez Gene ID: (Human) 10015
cell separation after cytokinesis
apoptotic process
nucleus organization
mitotic metaphase plate congression
regulation of centrosome duplication
protein transport
viral life cycle
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of exosomal secretion
regulation of extracellular exosome assembly
positive regulation of extracellular exosome assembly
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