Proteintech

Alpha SMA Polyclonal Antibody

Alpha SMA Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Alpha SMA Antibody (55135-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue slide using (Product # 55135-1-AP) smooth muscle actin specific antibody at dilution of 1:1,000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Alpha SMA Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))

Product Image Gallery

Product Details

55135-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 143 publications 143 publications

Immunohistochemistry (IHC)

View 52 publications 52 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 91 publications 91 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rabbit, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody stains the aorta only.

Target Information

Smooth Muscle Actin belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. In particular, smooth muscle actin is an alpha actin that is found in skeletal muscle. Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. Smooth muscle actin is found on smooth muscle vessel walls, gut wall, myometrium, myoepithelial cells in breast and salivary glands. Defects in the smooth muscle actin gene cause aortic aneurysm familial thoracic type 6. Actin isoforms differ slightly in their N-terminus and the sequences of each are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown that smooth muscle actin appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases. Multiple alternatively spliced variants of smooth muscle actin have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Wang P,Hao P,Chen X,Li L,Zhou Y,Zhang X,Zhu L,Ying M,Han R,Wang L,Li X

Sat Jul 16 00:00:00 EDT 2022

The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice.

Toxicology letters

Guan S,Liu H,Zhou J,Zhang Q,Bi H

Wed Jun 15 00:00:00 EDT 2022

The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice.

Toxicology letters

Guan S,Liu H,Zhou J,Zhang Q,Bi H

Wed Jun 15 00:00:00 EDT 2022

Effective delivery of osteopontin small interference RNA using exosomes suppresses liver fibrosis via TGF-β1 signaling.

Frontiers in pharmacology

Tang M,Guo C,Sun M,Zhou H,Peng X,Dai J,Ding Q,Wang Y,Yang C

Tue Sep 20 00:00:00 EDT 2022

Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice.

Frontiers in pharmacology

Gu YH,Ren KW,Wang Y,Wang SH,Yu XH,Xu LW,Li HH,Bi HL

Fri Nov 18 00:00:00 EST 2022

Disulfiram attenuates hypoxia-induced pulmonary hypertension by inhibiting GSDMD cleavage and pyroptosis in HPASMCs.

Respiratory research

Hu S,Wang L,Xu Y,Li F,Wang T

Fri Dec 16 00:00:00 EST 2022

Sterol-resistant SCAP Overexpression in Vascular Smooth Muscle Cells Accelerates Atherosclerosis by Increasing Local Vascular Inflammation through Activation of the NLRP3 Inflammasome in Mice.

Aging and disease

Li D,Liu M,Li Z,Zheng G,Chen A,Zhao L,Yang P,Wei L,Chen Y,Ruan XZ

Tue Jun 01 00:00:00 EDT 2021

miR-506-3p regulates TGF- 1 and affects dermal fibroblast proliferation, migration and collagen formation after thermal injury.

Tissue & cell

Yang M,Yang Z,Pan X,Huang X,Yang L,Xue Y

Fri Oct 01 00:00:00 EDT 2021

MiR-32-5p knockdown inhibits epithelial to mesenchymal transition and renal fibrosis by targeting SMAD7 in diabetic nephropathy.

Human & experimental toxicology

Wang HJ,Liu H,Lin YH,Zhang SJ

Thu Apr 01 00:00:00 EDT 2021

Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.

Ecotoxicology and environmental safety

Zhou X,Zhang T,Song L,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhang W,Song N,Wang S

Sun Aug 01 00:00:00 EDT 2021

Prenatal exposure to di-n-butyl phthalate induces erectile dysfunction in male adult rats.

Ecotoxicology and environmental safety

Zhou X,Zhang T,Song L,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhang W,Song N,Wang S

Sun Aug 01 00:00:00 EDT 2021

Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF^V600E Mutant Melanoma Lung Metastasis in Mice.

International journal of molecular sciences

Cvetanova B,Li MY,Yang CC,Hsiao PW,Yang YC,Feng JH,Shen YC,Nakagawa-Goto K,Lee KH,Shyur LF

Mon Mar 22 00:00:00 EDT 2021

USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.

Frontiers in cell and developmental biology

Zhu S,Hou S,Lu Y,Sheng W,Cui Z,Dong T,Feng H,Wan Q

Thu May 13 00:00:00 EDT 2021

Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.

Journal of cardiovascular pharmacology

Shi X,Zhang Y,Han J,Peng W,Fang Z,Qin Y,Xu X,Lin J,Xiao F,Zhao L,Lin Y

Sat May 01 00:00:00 EDT 2021

Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.

Journal of cardiovascular pharmacology

Shi X,Zhang Y,Han J,Peng W,Fang Z,Qin Y,Xu X,Lin J,Xiao F,Zhao L,Lin Y

Sat May 01 00:00:00 EDT 2021

Tryptanthrin Regulates Vascular Smooth Muscle Cell Phenotypic Switching in Atherosclerosis by AMP-Activated Protein Kinase/Acetyl-CoA Carboxylase Signaling Pathway.

Journal of cardiovascular pharmacology

Shi X,Zhang Y,Han J,Peng W,Fang Z,Qin Y,Xu X,Lin J,Xiao F,Zhao L,Lin Y

Sat May 01 00:00:00 EDT 2021

Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.

International immunopharmacology

Shao S,Qu Z,Liang Y,Xu Y,Zhou D,Li D,Zhang Y,Yin S

Fri Oct 01 00:00:00 EDT 2021

Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.

International immunopharmacology

Shao S,Qu Z,Liang Y,Xu Y,Zhou D,Li D,Zhang Y,Yin S

Fri Oct 01 00:00:00 EDT 2021

Ketogenic diet induces autophagy to alleviate bleomycin-induced pulmonary fibrosis in murine models.

Experimental lung research

Mu E,Wang J,Chen L,Lin S,Chen J,Huang X

Mon Feb 01 00:00:00 EST 2021

General Control of Amino Acid Synthesis 5-Like 1-Mediated Acetylation of Manganese Superoxide Dismutase Regulates Oxidative Stress in Diabetic Kidney Disease.

Oxidative medicine and cellular longevity

Lv T,Lu Y,Liu Y,Feng H,Li C,Sheng W,Cui Z,Zhu S,Gu X,Yang Z,Wan Q

Thu May 20 00:00:00 EDT 2021

General Control of Amino Acid Synthesis 5-Like 1-Mediated Acetylation of Manganese Superoxide Dismutase Regulates Oxidative Stress in Diabetic Kidney Disease.

Oxidative medicine and cellular longevity

Lv T,Lu Y,Liu Y,Feng H,Li C,Sheng W,Cui Z,Zhu S,Gu X,Yang Z,Wan Q

Thu May 20 00:00:00 EDT 2021

Zi Qi Decoction Alleviates Liver Fibrosis by Inhibiting the Toll-Like Receptor 4 (TLR4)-Related Nuclear Factor kappa b (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways.

Medical science monitor : international medical journal of experimental and clinical research

Zhou J,Zhang X,Wan L,Yu J,Li T,Lu Z,Fang N,Sun L,Ye F

Wed Apr 14 00:00:00 EDT 2021

Treatment of keloids through Runx2 siRNA‑induced inhibition of the PI3K/AKT signaling pathway.

Molecular medicine reports

Lv W,Wu M,Ren Y,Luo X,Hu W,Zhang Q,Wu Y

Fri Jan 01 00:00:00 EST 2021

MicroRNA-489-3p Represses Hepatic Stellate Cells Activation by Negatively Regulating the JAG1/Notch3 Signaling Pathway.

Digestive diseases and sciences

Li J,Dong S,Ye M,Peng G,Luo J,Wang C,Wang J,Zhao Q,Chang Y,Wang H

Fri Jan 01 00:00:00 EST 2021

Anti-fibrotic properties of an adiponectin paralog protein, C1q/TNF-related protein 6 (CTRP6), in diffuse gastric adenocarcinoma.

Journal of Cancer

Iwata Y,Yasufuku I,Saigo C,Kito Y,Takeuchi T,Yoshida K

Fri Jan 15 00:00:00 EST 2021

Anti-fibrotic properties of an adiponectin paralog protein, C1q/TNF-related protein 6 (CTRP6), in diffuse gastric adenocarcinoma.

Journal of Cancer

Iwata Y,Yasufuku I,Saigo C,Kito Y,Takeuchi T,Yoshida K

Fri Jan 15 00:00:00 EST 2021

Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis.

Cell death & disease

Liu G,Sun J,Yang ZF,Zhou C,Zhou PY,Guan RY,Sun BY,Wang ZT,Zhou J,Fan J,Qiu SJ,Yi Y

Thu Mar 11 00:00:00 EST 2021

Cancer-associated fibroblast-derived CXCL11 modulates hepatocellular carcinoma cell migration and tumor metastasis through the circUBAP2/miR-4756/IFIT1/3 axis.

Cell death & disease

Liu G,Sun J,Yang ZF,Zhou C,Zhou PY,Guan RY,Sun BY,Wang ZT,Zhou J,Fan J,Qiu SJ,Yi Y

Thu Mar 11 00:00:00 EST 2021

The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.

Life sciences

Li J,Zhang X,Wang T,Li J,Su Q,Zhong C,Chen Z,Liang Y

Mon Mar 15 00:00:00 EDT 2021

The antioxidant N-acetylcysteine promotes immune response and inhibits epithelial-mesenchymal transition to alleviate pulmonary fibrosis in chronic obstructive pulmonary disease by suppressing the VWF/p38 MAPK axis.

Molecular medicine (Cambridge, Mass.)

Zhu L,Xu F,Kang X,Zhou J,Yao Q,Lin Y,Zhang W

Fri Sep 03 00:00:00 EDT 2021

S-Nitroso-L-Cysteine Ameliorated Pulmonary Hypertension in the MCT-Induced Rats through Anti-ROS and Anti-Inflammatory Pathways.

Oxidative medicine and cellular longevity

Wang M,Luo P,Shi W,Guo J,Huo S,Yan D,Peng L,Zhang C,Lv J,Lin L,Li S

Tue May 18 00:00:00 EDT 2021

WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.

Experimental & molecular medicine

Sun C,Ma Q,Yin J,Zhang H,Liu X

Tue Jun 01 00:00:00 EDT 2021

WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.

Experimental & molecular medicine

Sun C,Ma Q,Yin J,Zhang H,Liu X

Tue Jun 01 00:00:00 EDT 2021

WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling.

Experimental & molecular medicine

Sun C,Ma Q,Yin J,Zhang H,Liu X

Tue Jun 01 00:00:00 EDT 2021

LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis.

ACS biomaterials science & engineering

Zhou M,Wang S,Liu D,Zhou J

Mon Nov 08 00:00:00 EST 2021

LINC01915 Facilitates the Conversion of Normal Fibroblasts into Cancer-Associated Fibroblasts Induced by Colorectal Cancer-Derived Extracellular Vesicles through the miR-92a-3p/KLF4/CH25H Axis.

ACS biomaterials science & engineering

Zhou M,Wang S,Liu D,Zhou J

Mon Nov 08 00:00:00 EST 2021

Increased nuclear translation of YAP might act as a potential therapeutic target for NF1-related plexiform neurofibroma.

International journal of medical sciences

Liu JL,You YH,Tian ZW,Xiao M,Zheng JW,Wang YA,Du Z

Thu Nov 04 00:00:00 EDT 2021

Transient Receptor Potential Melastatin 7 Promotes Vascular Adventitial Fibroblasts Phenotypic Transformation and Inflammatory Reaction Induced by Mechanical Stretching Stress via p38 MAPK/JNK Pathway.

Journal of vascular research

Liu J,Chen L,Huang J,Guo S,Zhu D,Gao P

Mon Dec 20 00:00:00 EST 2021

Journal of vascular research

Liu J,Chen L,Huang J,Guo S,Zhu D,Gao P

Mon Dec 20 00:00:00 EST 2021

A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment.

Cancer cell international

Chen J,Han S,Chen J,Hu P,Zeng Z,Hu Y,Xiong H,Ke Z,Zhang Y,Xu F,Zhao G

Mon Dec 20 00:00:00 EST 2021

COL5A1 Variants Cause Aortic Dissection by Activating TGF-β-Signaling Pathway.

Journal of the American Heart Association

Chen P,Yu B,Li Z,Chen Y,Sun Y,Wang DW

Tue Jun 01 00:00:00 EDT 2021

MicroRNA-503 Targets Mothers Against Decapentaplegic Homolog 7 Enhancing Hepatic Stellate Cell Activation and Hepatic Fibrosis.

Digestive diseases and sciences

Xie X,Dou CY,Zhou Y,Zhou Q,Tang HB

Tue Jun 01 00:00:00 EDT 2021

MicroRNA-503 Targets Mothers Against Decapentaplegic Homolog 7 Enhancing Hepatic Stellate Cell Activation and Hepatic Fibrosis.

Digestive diseases and sciences

Xie X,Dou CY,Zhou Y,Zhou Q,Tang HB

Tue Jun 01 00:00:00 EDT 2021

MicroRNA-503 Targets Mothers Against Decapentaplegic Homolog 7 Enhancing Hepatic Stellate Cell Activation and Hepatic Fibrosis.

Digestive diseases and sciences

Xie X,Dou CY,Zhou Y,Zhou Q,Tang HB

Tue Jun 01 00:00:00 EDT 2021

MicroRNA-503 Targets Mothers Against Decapentaplegic Homolog 7 Enhancing Hepatic Stellate Cell Activation and Hepatic Fibrosis.

Digestive diseases and sciences

Xie X,Dou CY,Zhou Y,Zhou Q,Tang HB

Tue Jun 01 00:00:00 EDT 2021

Citrus Alkaline Extracts Inhibit Senescence of A549 Cells to Alleviate Pulmonary Fibrosis via the β-Catenin/P53 Pathway.

Medical science monitor : international medical journal of experimental and clinical research

Han D,Xu Y,Peng WP,Feng F,Wang Z,Gu C,Zhou X

Fri Mar 12 00:00:00 EST 2021

SOD3 deficiency induces liver fibrosis by promoting hepatic stellate cell activation and epithelial-mesenchymal transition.

Journal of cellular physiology

Sun YL,Bai T,Zhou L,Zhu RT,Wang WJ,Liang RP,Li J,Zhang CX,Gou JJ

Tue Jun 01 00:00:00 EDT 2021

Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.

Pediatric pulmonology

Mou Q,Ji B,Zhao G,Liu Y,Sakurai R,Xie Y,Zhang Q,Dai J,Lu Y,Ge Y,Shi T,Xu S,Rehan VK

Sun Aug 01 00:00:00 EDT 2021

Effect of Shenkang on renal fibrosis and activation of renal interstitial fibroblasts through the JAK2/STAT3 pathway.

BMC complementary medicine and therapies

Qin T,Wu Y,Liu T,Wu L

Wed Jan 06 00:00:00 EST 2021

HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210.

Aging and disease

Yang Y,Gu J,Li X,Xue C,Ba L,Gao Y,Zhou J,Bai C,Sun Z,Zhao RC

Fri Oct 01 00:00:00 EDT 2021

HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210.

Aging and disease

Yang Y,Gu J,Li X,Xue C,Ba L,Gao Y,Zhou J,Bai C,Sun Z,Zhao RC

Fri Oct 01 00:00:00 EDT 2021

HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210.

Aging and disease

Yang Y,Gu J,Li X,Xue C,Ba L,Gao Y,Zhou J,Bai C,Sun Z,Zhao RC

Fri Oct 01 00:00:00 EDT 2021

HIF-1α promotes the migration and invasion of cancer-associated fibroblasts by miR-210.

Aging and disease

Yang Y,Gu J,Li X,Xue C,Ba L,Gao Y,Zhou J,Bai C,Sun Z,Zhao RC

Fri Oct 01 00:00:00 EDT 2021

MicroRNA‑199a‑5p regulates FOXC2 to control human vascular smooth muscle cell phenotypic switch.

Molecular medicine reports

Cao Y,Cao Z,Wang W,Jie X,Li L

Wed Sep 01 00:00:00 EDT 2021

A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.

Toxicology letters

Liao J,Zhang Z,Yuan Q,Liu Q,Kuang J,Fang Y,Hu X

Fri Jan 01 00:00:00 EST 2021

A lncRNA Gpr137b-ps/miR-200a-3p/CXCL14 axis modulates hepatic stellate cell (HSC) activation.

Toxicology letters

Liao J,Zhang Z,Yuan Q,Liu Q,Kuang J,Fang Y,Hu X

Fri Jan 01 00:00:00 EST 2021

Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.

Clinical and translational medicine

Liu AD,Zhou J,Bi XY,Hou GQ,Li SS,Chen Q,Xu H,Cao X

Mon Mar 01 00:00:00 EST 2021

Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.

Cellular signalling

Peng YF,Lin H,Liu DC,Zhu XY,Huang N,Wei YX,Li L

Sun Aug 01 00:00:00 EDT 2021

Heat shock protein 90 inhibitor ameliorates pancreatic fibrosis by degradation of transforming growth factor-β receptor.

Cellular signalling

Peng YF,Lin H,Liu DC,Zhu XY,Huang N,Wei YX,Li L

Sun Aug 01 00:00:00 EDT 2021

Ppic modulates CCl₄-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p.

Toxicology letters

Yang X,Shu B,Zhou Y,Li Z,He C

Sun Oct 10 00:00:00 EDT 2021

Ppic modulates CCl₄-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p.

Toxicology letters

Yang X,Shu B,Zhou Y,Li Z,He C

Sun Oct 10 00:00:00 EDT 2021

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Aging

Liu H,Yan R,Liang L,Zhang H,Xiang J,Liu L,Zhang X,Mao Y,Peng W,Xiao Y,Zhang F,Zhou Y,Shi M,Wang Y,Guo B

Wed Feb 17 00:00:00 EST 2021

Mesenchymal stem/stromal cells-derived IL-6 promotes nasopharyngeal carcinoma growth and resistance to cisplatin via upregulating CD73 expression.

Journal of Cancer

Zeng J,Chen S,Li C,Ye Z,Lin B,Liang Y,Wang B,Ma Y,Chai X,Zhang X,Zhou K,Zhang Q,Zhang H

Mon Sep 28 00:00:00 EDT 2020

Mesenchymal stem/stromal cells-derived IL-6 promotes nasopharyngeal carcinoma growth and resistance to cisplatin via upregulating CD73 expression.

Journal of Cancer

Zeng J,Chen S,Li C,Ye Z,Lin B,Liang Y,Wang B,Ma Y,Chai X,Zhang X,Zhou K,Zhang Q,Zhang H

Mon Sep 28 00:00:00 EDT 2020

Mesenchymal stem/stromal cells-derived IL-6 promotes nasopharyngeal carcinoma growth and resistance to cisplatin via upregulating CD73 expression.

Journal of Cancer

Zeng J,Chen S,Li C,Ye Z,Lin B,Liang Y,Wang B,Ma Y,Chai X,Zhang X,Zhou K,Zhang Q,Zhang H

Mon Sep 28 00:00:00 EDT 2020

Mesenchymal stem/stromal cells-derived IL-6 promotes nasopharyngeal carcinoma growth and resistance to cisplatin via upregulating CD73 expression.

Journal of Cancer

Zeng J,Chen S,Li C,Ye Z,Lin B,Liang Y,Wang B,Ma Y,Chai X,Zhang X,Zhou K,Zhang Q,Zhang H

Mon Sep 28 00:00:00 EDT 2020

Plasma proteomic analysis of autoimmune hepatitis in an improved AIH mouse model.

Journal of translational medicine

Wang H,Yan W,Feng Z,Gao Y,Zhang L,Feng X,Tian D

Mon Jan 06 00:00:00 EST 2020

Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.

Cell biology international

Sun D,Yang L,Cao H,Shen ZY,Song HL

Sat Feb 01 00:00:00 EST 2020

Study of the protective effect on damaged intestinal epithelial cells of rat multilineage-differentiating stress-enduring (Muse) cells.

Cell biology international

Sun D,Yang L,Cao H,Shen ZY,Song HL

Sat Feb 01 00:00:00 EST 2020

Blockade of extracellular high-mobility group box 1 attenuates inflammation-mediated damage and haze grade in mice with corneal wounds.

International immunopharmacology

Zhou Y,Wang T,Wang Y,Meng F,Ying M,Han R,Hao P,Wang L,Li X

Mon Jun 01 00:00:00 EDT 2020

Circular RNA expression profiling identifies novel biomarkers in uterine leiomyoma.

Cellular signalling

Wang W,Zhou L,Wang J,Zhang X,Liu G

Tue Dec 01 00:00:00 EST 2020

Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure.

Aging

He F,Li L,Li PP,Deng Y,Yang YY,Deng YX,Luo HH,Yao XT,Su YX,Gan H,He BC

Fri Nov 06 00:00:00 EST 2020

Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS.

Clinical science (London, England : 1979)

Huang Y,Li Y,Lou A,Wang GZ,Hu Y,Zhang Y,Huang W,Wang J,Li Y,Zhu X,Chen T,Lin J,Meng Y,Li X

Fri Apr 17 00:00:00 EDT 2020

Alamandine attenuates hepatic fibrosis by regulating autophagy induced by NOX4-dependent ROS.

Clinical science (London, England : 1979)

Huang Y,Li Y,Lou A,Wang GZ,Hu Y,Zhang Y,Huang W,Wang J,Li Y,Zhu X,Chen T,Lin J,Meng Y,Li X

Fri Apr 17 00:00:00 EDT 2020

The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.

Oncology research

Wei W,Ma XD,Jiang GM,Shi B,Zhong W,Sun CL,Zhao L,Hou YJ,Wang H

Tue Sep 01 00:00:00 EDT 2020

MiRNA-451a inhibits airway remodeling by targeting Cadherin 11 in an allergic asthma model of neonatal mice.

International immunopharmacology

Wang T,Zhou Q,Shang Y

Mon Jun 01 00:00:00 EDT 2020

MiRNA-451a inhibits airway remodeling by targeting Cadherin 11 in an allergic asthma model of neonatal mice.

International immunopharmacology

Wang T,Zhou Q,Shang Y

Mon Jun 01 00:00:00 EDT 2020

KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.

BMJ open diabetes research & care

Yang X,Yang R,Chen M,Zhou Q,Zheng Y,Lu C,Bi J,Sun W,Huang T,Li L,Gong J,Li X,Hui Q,Wang X

Fri May 01 00:00:00 EDT 2020

KGF-2 and FGF-21 poloxamer 407 hydrogel coordinates inflammation and proliferation homeostasis to enhance wound repair of scalded skin in diabetic rats.

BMJ open diabetes research & care

Yang X,Yang R,Chen M,Zhou Q,Zheng Y,Lu C,Bi J,Sun W,Huang T,Li L,Gong J,Li X,Hui Q,Wang X

Fri May 01 00:00:00 EDT 2020

RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.

Cell stress & chaperones

Shi L,Liu BY,Wang X,Zhu MJ,Chen L,Zhou MY,Gu YJ,Cheng L,Wang Y

Tue Sep 01 00:00:00 EDT 2020

RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.

Cell stress & chaperones

Shi L,Liu BY,Wang X,Zhu MJ,Chen L,Zhou MY,Gu YJ,Cheng L,Wang Y

Tue Sep 01 00:00:00 EDT 2020

RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.

Cell stress & chaperones

Shi L,Liu BY,Wang X,Zhu MJ,Chen L,Zhou MY,Gu YJ,Cheng L,Wang Y

Tue Sep 01 00:00:00 EDT 2020

MicroRNA-27a targets Sfrp1 to induce renal fibrosis in diabetic nephropathy by activating Wnt/β-Catenin signalling.

Bioscience reports

Shi M,Tian P,Liu Z,Zhang F,Zhang Y,Qu L,Liu X,Wang Y,Zhou X,Xiao Y,Guo B

Fri Jun 26 00:00:00 EDT 2020

MicroRNA-27a targets Sfrp1 to induce renal fibrosis in diabetic nephropathy by activating Wnt/β-Catenin signalling.

Bioscience reports

Shi M,Tian P,Liu Z,Zhang F,Zhang Y,Qu L,Liu X,Wang Y,Zhou X,Xiao Y,Guo B

Fri Jun 26 00:00:00 EDT 2020

Alteration of N⁶-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy.

Epigenomics

Li X,Fan X,Yin X,Liu H,Yang Y

Wed Jul 01 00:00:00 EDT 2020

Detrimental Effect of Sitagliptin Induced Autophagy on Multiterritory Perforator Flap Survival.

Frontiers in pharmacology

Chen Z,Zhang C,Ma H,Huang Z,Li J,Lou J,Li B,Tu Q,Gao W

Mon Sep 28 00:00:00 EDT 2020

Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin.

Biochemical pharmacology

Zeng Y,Hua YQ,Wang W,Zhang H,Xu XL

Fri May 01 00:00:00 EDT 2020

Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1.

Frontiers in pharmacology

Yang Y,Wang Y,He Z,Liu Y,Chen C,Wang Y,Wang DW,Wang H

Mon Sep 28 00:00:00 EDT 2020

Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1.

Frontiers in pharmacology

Yang Y,Wang Y,He Z,Liu Y,Chen C,Wang Y,Wang DW,Wang H

Mon Sep 28 00:00:00 EDT 2020

Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling.

Cell death and differentiation

Zhang N,Zhang Y,Qian H,Wu S,Cao L,Sun Y

Tue Sep 01 00:00:00 EDT 2020

Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene.

Stem cell research

Wang X,Xie S,Li Z,Ye Z,Gu X,Zhou L,Li H

Wed Jan 01 00:00:00 EST 2020

CD63⁺ Cancer-Associated Fibroblasts Confer Tamoxifen Resistance to Breast Cancer Cells through Exosomal miR-22.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Gao Y,Li X,Zeng C,Liu C,Hao Q,Li W,Zhang K,Zhang W,Wang S,Zhao H,Fan D,Li M,Zhang Y,Zhang W,Zhang C

Sun Nov 01 00:00:00 EDT 2020

Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.

International journal of molecular medicine

Wang X,Lin L,Chai X,Wu Y,Li Y,Liu X

Wed Jan 01 00:00:00 EST 2020

Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.

International journal of molecular medicine

Wang X,Lin L,Chai X,Wu Y,Li Y,Liu X

Wed Jan 01 00:00:00 EST 2020

Citri Reticulatae Pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ.

Annals of translational medicine

Cheng H,Wu X,Ni G,Wang S,Peng W,Zhang H,Gao J,Li X

Sun Nov 01 00:00:00 EDT 2020

Psoralen attenuates bleomycin-induced pulmonary fibrosis in mice through inhibiting myofibroblast activation and collagen deposition.

Cell biology international

Du MY,Duan JX,Zhang CY,Yang HH,Guan XX,Zhong WJ,Liu YZ,Li ZM,Cheng YR,Zhou Y,Guan CX

Wed Jan 01 00:00:00 EST 2020

Upregulated miR-101 inhibits acute kidney injury-chronic kidney disease transition by regulating epithelial-mesenchymal transition.

Human & experimental toxicology

Zhao JY,Wang XL,Yang YC,Zhang B,Wu YB

Tue Dec 01 00:00:00 EST 2020

CD66b⁺ neutrophils and α-SMA⁺ fibroblasts predict clinical outcomes and benefits from postoperative chemotherapy in gastric adenocarcinoma.

Cancer medicine

Cong X,Zhang Y,Zhu Z,Li S,Yin X,Zhai Z,Zhang Y,Xue Y

Wed Apr 01 00:00:00 EDT 2020

Exosomes derived from TSG-6 modified mesenchymal stromal cells attenuate scar formation during wound healing.

Biochimie

Jiang L,Zhang Y,Liu T,Wang X,Wang H,Song H,Wang W

Thu Oct 01 00:00:00 EDT 2020

Inhibition of vascular calcification by microRNA-155-5p is accompanied by the inactivation of TGF-β1/Smad2/3 signaling pathway.

Acta histochemica

Zhao F,Wu Y,Yang W,Wu D,Wang C,Zhang F

Fri May 01 00:00:00 EDT 2020

miR-181a/b-5p ameliorates inflammatory response in monocrotaline-induced pulmonary arterial hypertension by targeting endocan.

Journal of cellular physiology

Zhao H,Guo Y,Sun Y,Zhang N,Wang X

Fri May 01 00:00:00 EDT 2020

miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1.

Toxicology and applied pharmacology

Zhao H,Wang Y,Zhang X,Guo Y,Wang X

Wed Jan 01 00:00:00 EST 2020

Lipopolysaccharide induces epithelial-mesenchymal transition of alveolar epithelial cells cocultured with macrophages possibly via the JAK2/STAT3 signaling pathway.

Human & experimental toxicology

Qin Y,Zhao P,Chen Y,Liu X,Dong H,Zheng W,Li C,Mao X,Li J

Sat Feb 01 00:00:00 EST 2020

Grape Seed Proanthocyanidin Extract Ameliorates Cardiac Remodelling After Myocardial Infarction Through PI3K/AKT Pathway in Mice.

Frontiers in pharmacology

Ruan Y,Jin Q,Zeng J,Ren F,Xie Z,Ji K,Wu L,Wu J,Li L

Tue Dec 22 00:00:00 EST 2020

Grape Seed Proanthocyanidin Extract Ameliorates Cardiac Remodelling After Myocardial Infarction Through PI3K/AKT Pathway in Mice.

Frontiers in pharmacology

Ruan Y,Jin Q,Zeng J,Ren F,Xie Z,Ji K,Wu L,Wu J,Li L

Tue Dec 22 00:00:00 EST 2020

Mitochondrial ATP synthase regulates corpus cavernosum smooth muscle cell function in vivo and in vitro.

Experimental and therapeutic medicine

Xu Z,Chen J,Cai J,Xiao Y,Wang Q,Chen S,Zhang L,Wu Z

Mon Jun 01 00:00:00 EDT 2020

Bioactive multi-engineered hydrogel offers simultaneous promise against antibiotic resistance and wound damage.

International journal of biological macromolecules

Zhang J,Ge J,Xu Y,Chen J,Zhou A,Sun L,Gao Y,Zhang Y,Gu T,Ning X

Tue Dec 01 00:00:00 EST 2020

TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.

Journal of cellular and molecular medicine

Xu S,Mao Y,Wu J,Feng J,Li J,Wu L,Yu Q,Zhou Y,Zhang J,Chen J,Ji J,Chen K,Wang F,Dai W,Fan X,Guo C

Fri May 01 00:00:00 EDT 2020

TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis.

Journal of cellular and molecular medicine

Xu S,Mao Y,Wu J,Feng J,Li J,Wu L,Yu Q,Zhou Y,Zhang J,Chen J,Ji J,Chen K,Wang F,Dai W,Fan X,Guo C

Fri May 01 00:00:00 EDT 2020

Estrogen facilitates gastric cancer cell proliferation and invasion through promoting the secretion of interleukin-6 by cancer-associated fibroblasts.

International immunopharmacology

Zhang Y,Cong X,Li Z,Xue Y

Wed Jan 01 00:00:00 EST 2020

Effect of levocetirizine hydrochloride on the growth of human dermal papilla cells: a preliminary study.

Annals of palliative medicine

Wen S,Wei J,Bao J,Guo T,Zheng W,Zhuang X,Lin Y

Sun Mar 01 00:00:00 EST 2020

Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhao Y,Sun D,Chen Y,Zhan K,Meng Q,Zhang X,Zhu L,Yao X

Thu Oct 01 00:00:00 EDT 2020

Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhao Y,Sun D,Chen Y,Zhan K,Meng Q,Zhang X,Zhu L,Yao X

Thu Oct 01 00:00:00 EDT 2020

miR-15a-5p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting VEGF in rats.

Renal failure

He Q,Wen L,Wang L,Zhang Y,Yu W,Zhang F,Zhang W,Xiao J,Wen X,Zhao Z

Sun Nov 01 00:00:00 EDT 2020

miR-15a-5p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting VEGF in rats.

Renal failure

He Q,Wen L,Wang L,Zhang Y,Yu W,Zhang F,Zhang W,Xiao J,Wen X,Zhao Z

Sun Nov 01 00:00:00 EDT 2020

Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis.

Journal of the American Heart Association

Saku K,Tahara N,Takaseya T,Otsuka H,Takagi K,Shojima T,Shintani Y,Zaima Y,Kikusaki S,Fukuda T,Oryoji A,Nishino Y,Matsui T,Kakuma T,Akiba J,Fukumoto Y,Yamagishi SI,Tanaka H

Tue Jul 07 00:00:00 EDT 2020

MiR-185-5p Protects Against Angiogenesis in Polycystic Ovary Syndrome by Targeting VEGFA.

Frontiers in pharmacology

Wei J,Zhao Y

Mon Sep 28 00:00:00 EDT 2020

MicroRNA-150 relieves vascular remodeling and fibrosis in hypoxia-induced pulmonary hypertension.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Li Y,Ren W,Wang X,Yu X,Cui L,Li X,Zhang X,Shi B

Tue Jan 01 00:00:00 EST 2019

MicroRNA-150 relieves vascular remodeling and fibrosis in hypoxia-induced pulmonary hypertension.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Li Y,Ren W,Wang X,Yu X,Cui L,Li X,Zhang X,Shi B

Tue Jan 01 00:00:00 EST 2019

Integrative proteomics and immunochemistry analysis of the factors in the necrosis and repair in acetaminophen-induced acute liver injury in mice.

Journal of cellular physiology

Feng Q,Zhao N,Xia W,Liang C,Dai G,Yang J,Sun J,Liu L,Luo L,Yang J

Wed May 01 00:00:00 EDT 2019

Integrative proteomics and immunochemistry analysis of the factors in the necrosis and repair in acetaminophen-induced acute liver injury in mice.

Journal of cellular physiology

Feng Q,Zhao N,Xia W,Liang C,Dai G,Yang J,Sun J,Liu L,Luo L,Yang J

Wed May 01 00:00:00 EDT 2019

Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.

Journal of gastroenterology and hepatology

Liu T,Xu L,Wang C,Chen K,Xia Y,Li J,Li S,Wu L,Feng J,Xu S,Wang W,Lu X,Fan X,Mo W,Zhou Y,Zhao Y,Guo C

Tue Jan 01 00:00:00 EST 2019

Alleviation of hepatic fibrosis and autophagy via inhibition of transforming growth factor-β1/Smads pathway through shikonin.

Journal of gastroenterology and hepatology

Liu T,Xu L,Wang C,Chen K,Xia Y,Li J,Li S,Wu L,Feng J,Xu S,Wang W,Lu X,Fan X,Mo W,Zhou Y,Zhao Y,Guo C

Tue Jan 01 00:00:00 EST 2019

Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression.

Cytotechnology

Fan H,Huang L,Zhuang X,Ai F,Sun W

Fri Feb 01 00:00:00 EST 2019

Angiopoietin-like protein 1 inhibits epithelial to mesenchymal transition in colorectal cancer cells via suppress Slug expression.

Cytotechnology

Fan H,Huang L,Zhuang X,Ai F,Sun W

Fri Feb 01 00:00:00 EST 2019

Adeno-associated virus 9-mediated RNA interference targeting SOCS3 alleviates diastolic heart failure in rats.

Gene

Gao J,Guo Y,Chen Y,Zhou J,Liu Y,Su P

Mon May 20 00:00:00 EDT 2019

TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.

International archives of allergy and immunology

Li X,Li C,Zhu G,Yuan W,Xiao ZA

Thu Sep 12 00:00:00 EDT 2019

TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.

International archives of allergy and immunology

Li X,Li C,Zhu G,Yuan W,Xiao ZA

Thu Sep 12 00:00:00 EDT 2019

Costunolide reduces glycolysis-associated activation of hepatic stellate cells via inhibition of hexokinase-2.

Cellular & molecular biology letters

Ban D,Hua S,Zhang W,Shen C,Miao X,Liu W

Mon Apr 06 00:00:00 EDT 2020

Schisandrin B attenuates renal fibrosis via miR-30e-mediated inhibition of EMT.

Toxicology and applied pharmacology

Cao G,Li S,Shi H,Yin P,Chen J,Li H,Zhong Y,Diao LT,Du B

Sun Dec 15 00:00:00 EST 2019

Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction.

Molecular medicine reports

Zhao J,Meng M,Zhang J,Li L,Zhu X,Zhang L,Wang C,Gao M

Mon Apr 01 00:00:00 EDT 2019

Extracellular vesicles of carcinoma-associated fibroblasts creates a pre-metastatic niche in the lung through activating fibroblasts.

Molecular cancer

Kong J,Tian H,Zhang F,Zhang Z,Li J,Liu X,Li X,Liu J,Li X,Jin D,Yang X,Sun B,Guo T,Luo Y,Lu Y,Lin B,Liu T

Tue Dec 03 00:00:00 EST 2019

Protective effects of 18β-glycyrrhetinic acid on pulmonary arterial hypertension via regulation of Rho A/Rho kinsase pathway.

Chemico-biological interactions

Zhang M,Chang Z,Zhang P,Jing Z,Yan L,Feng J,Hu Z,Xu Q,Zhou W,Ma P,Hao Y,Zhou R

Wed Sep 25 00:00:00 EDT 2019

Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.

Molecular and cellular biochemistry

Zhu D,Zhao J,Lou A,Huang Q,OuYang Q,Zhu J,Fan M,He Y,Ren H,Yang M

Sun Sep 01 00:00:00 EDT 2019

Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.

Molecular and cellular biochemistry

Zhu D,Zhao J,Lou A,Huang Q,OuYang Q,Zhu J,Fan M,He Y,Ren H,Yang M

Sun Sep 01 00:00:00 EDT 2019

α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy.

Molecular medicine reports

Liu G,Liu J,Pian L,Gui S,Lu B

Fri Feb 01 00:00:00 EST 2019

α‑lipoic acid protects against carbon tetrachloride‑induced liver cirrhosis through the suppression of the TGF‑β/Smad3 pathway and autophagy.

Molecular medicine reports

Liu G,Liu J,Pian L,Gui S,Lu B

Fri Feb 01 00:00:00 EST 2019

Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90.

Toxicology and applied pharmacology

Yu Z,Jv Y,Cai L,Tian X,Huo X,Wang C,Zhang B,Sun C,Ning J,Feng L,Zhang H,Ma X

Wed May 15 00:00:00 EDT 2019

Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.

Experimental eye research

Hu L,Pu Q,Zhang Y,Ma Q,Li G,Li X

Wed May 01 00:00:00 EDT 2019

Role of CCR2 in the Development of Streptozotocin-Treated Diabetic Cardiomyopathy.

Diabetes

Tan X,Hu L,Shu Z,Chen L,Li X,Du M,Sun D,Mao X,Deng S,Huang K,Zhang F

Fri Nov 01 00:00:00 EDT 2019

Cigarette smoke exposure combined with lipopolysaccharides induced pulmonary fibrosis in mice.

Respiratory physiology & neurobiology

Fang L,Cheng Q,Zhao F,Cheng H,Luo Y,Bao X,Li Y,Liang X,Huang Y,Xu J,Han J,Tang Y,Tang S,Liu W,Luo Z,Feng D

Thu Aug 01 00:00:00 EDT 2019

Rosiglitazone attenuates paraquat-induced lung fibrosis in rats in a PPAR gamma-dependent manner.

European journal of pharmacology

Zhang H,You L,Zhao M

Wed May 15 00:00:00 EDT 2019

New FH peptide-modified ultrasonic nanobubbles for delivery of doxorubicin to cancer-associated fibroblasts.

Nanomedicine (London, England)

Guo L,Shi D,Meng D,Shang M,Sun X,Zhou X,Liu X,Zhao Y,Li J

Fri Nov 01 00:00:00 EDT 2019

Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.

Theranostics

Zhu Y,Yu F,Tan Y,Hong Y,Meng T,Liu Y,Dai S,Qiu G,Yuan H,Hu F

Fri Jul 24 00:00:00 EDT 2020

Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.

Theranostics

Zhu Y,Yu F,Tan Y,Hong Y,Meng T,Liu Y,Dai S,Qiu G,Yuan H,Hu F

Fri Jul 24 00:00:00 EDT 2020

Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.

Theranostics

Zhu Y,Yu F,Tan Y,Hong Y,Meng T,Liu Y,Dai S,Qiu G,Yuan H,Hu F

Fri Jul 24 00:00:00 EDT 2020

Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.

Theranostics

Zhu Y,Yu F,Tan Y,Hong Y,Meng T,Liu Y,Dai S,Qiu G,Yuan H,Hu F

Fri Jul 24 00:00:00 EDT 2020

Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.

Evidence-based complementary and alternative medicine : eCAM

Xia CH,Han XT,Zhang X,Zhu ZB,Guo J,Cui HL,Jiang HX,Huang WJ,Chen GZ,Liu YN,Liu WJ

Wed Sep 30 00:00:00 EDT 2020

Yiqihuoxue Formula Activates Autophagy and Offers Renoprotection in a Rat Model of Adenine-Induced Kidney Disease.

Evidence-based complementary and alternative medicine : eCAM

Xia CH,Han XT,Zhang X,Zhu ZB,Guo J,Cui HL,Jiang HX,Huang WJ,Chen GZ,Liu YN,Liu WJ

Wed Sep 30 00:00:00 EDT 2020

Inhibitory effects of octreotide on the progression of hepatic fibrosis via the regulation of Bcl-2/Bax and PI3K/AKT signaling pathways.

International immunopharmacology

Zhang C,An R,Bao YW,Meng XM,Wang TQ,Sun HN,Pan FM,Zhang C

Thu Aug 01 00:00:00 EDT 2019

Inhibitory effects of octreotide on the progression of hepatic fibrosis via the regulation of Bcl-2/Bax and PI3K/AKT signaling pathways.

International immunopharmacology

Zhang C,An R,Bao YW,Meng XM,Wang TQ,Sun HN,Pan FM,Zhang C

Thu Aug 01 00:00:00 EDT 2019

Rutaecarpine prevented ox-LDL-induced VSMCs dysfunction through inhibiting overexpression of connexin 43.

European journal of pharmacology

Wang M,Wu Y,Yu Y,Fu Y,Yan H,Wang X,Li T,Peng W,Luo D

Sat Jun 15 00:00:00 EDT 2019

Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway.

The American journal of Chinese medicine

Zhou X,Xiong J,Lu S,Luo L,Chen ZL,Yang F,Jin F,Wang Y,Ma Q,Luo YY,Wang YJ,Zhou JB,Liu P,Zhao L

Fri Apr 03 00:00:00 EDT 2020

A Novel Liposomal S-Propargyl-Cysteine: A Sustained Release of Hydrogen Sulfide Reducing Myocardial Fibrosis via TGF-β1/Smad Pathway.

International journal of nanomedicine

Tran BH,Yu Y,Chang L,Tan B,Jia W,Xiong Y,Dai T,Zhong R,Zhang W,Le VM,Rose P,Wang Z,Mao Y,Zhu YZ

Fri Mar 13 00:00:00 EDT 2020

Scoparone alleviates inflammation, apoptosis and fibrosis of non-alcoholic steatohepatitis by suppressing the TLR4/NF-κB signaling pathway in mice.

International immunopharmacology

Liu B,Deng X,Jiang Q,Li G,Zhang J,Zhang N,Xin S,Xu K

Tue Oct 01 00:00:00 EDT 2019

miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.

EBioMedicine

Wang M,Xiong L,Jiang LJ,Lu YZ,Liu F,Song LJ,Xiang F,He XL,Yu F,Shuai SY,Ma WL,Ye H

Fri Mar 01 00:00:00 EST 2019

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Theranostics

Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J

Fri Jan 31 00:00:00 EST 2020

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Theranostics

Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J

Fri Jan 31 00:00:00 EST 2020

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Theranostics

Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J

Fri Jan 31 00:00:00 EST 2020

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Theranostics

Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J

Fri Jan 31 00:00:00 EST 2020

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Theranostics

Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J

Fri Jan 31 00:00:00 EST 2020

p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species.

Theranostics

Zhao Y,Wang Z,Feng D,Zhao H,Lin M,Hu Y,Zhang N,Lv L,Gao Z,Zhai X,Tian X,Yao J

Fri Jan 31 00:00:00 EST 2020

The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.

Journal of cellular and molecular medicine

Xue K,Zhang J,Li C,Li J,Wang C,Zhang Q,Chen X,Yu X,Sun L,Yu X

Sat Jun 01 00:00:00 EDT 2019

The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis.

Journal of cellular and molecular medicine

Xue K,Zhang J,Li C,Li J,Wang C,Zhang Q,Chen X,Yu X,Sun L,Yu X

Sat Jun 01 00:00:00 EDT 2019

Ex vivo detection of cadmium-induced renal damage by using confocal Raman spectroscopy.

Journal of biophotonics

Shen R,Li Y,Yu L,Wu H,Cui R,Liu S,Song Y,Wang D

Sun Dec 01 00:00:00 EST 2019

Inhibitory effects of total ginsenoside on bleomycin-induced pulmonary fibrosis in mice.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yang L,Chen PP,Luo M,Shi WL,Hou DS,Gao Y,Xu SF,Deng J

Sat Jun 01 00:00:00 EDT 2019

Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection.

Biomolecules

Chen TT,Peng S,Wang Y,Hu Y,Shen Y,Xu Y,Yin J,Liu C,Cao J

Fri Oct 25 00:00:00 EDT 2019

Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer.

Cell death & disease

Zhang R,Qi F,Zhao F,Li G,Shao S,Zhang X,Yuan L,Feng Y

Wed Mar 20 00:00:00 EDT 2019

Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer.

Cell death & disease

Zhang R,Qi F,Zhao F,Li G,Shao S,Zhang X,Yuan L,Feng Y

Wed Mar 20 00:00:00 EDT 2019

Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.

Journal of cellular physiology

Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H

Sun Sep 01 00:00:00 EDT 2019

Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.

Journal of cellular physiology

Song S,Qiu D,Shi Y,Wang S,Zhou X,Chen N,Wei J,Wu M,Wu H,Duan H

Sun Sep 01 00:00:00 EDT 2019

Role of mTOR signaling in the regulation of high glucose-induced podocyte injury.

Experimental and therapeutic medicine

Li Q,Zeng Y,Jiang Q,Wu C,Zhou J

Mon Apr 01 00:00:00 EDT 2019

Nicotinamide inhibits corneal endothelial mesenchymal transition and accelerates wound healing.

Experimental eye research

Li Z,Duan H,Li W,Jia Y,Zhang S,Zhao C,Zhou Q,Shi W

Mon Jul 01 00:00:00 EDT 2019

Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.

Cancer biology & therapy

Zhu HF,Zhang XH,Gu CS,Zhong Y,Long T,Ma YD,Hu ZY,Li ZG,Wang XY

Wed Jul 29 00:00:00 EDT 2020

Cancer-associated fibroblasts promote colorectal cancer progression by secreting CLEC3B.

Cancer biology & therapy

Zhu HF,Zhang XH,Gu CS,Zhong Y,Long T,Ma YD,Hu ZY,Li ZG,Wang XY

Wed Jul 29 00:00:00 EDT 2020

Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Kong D,Zhang D,Cui Q,Wang K,Tang J,Liu Z,Wu G

Wed May 01 00:00:00 EDT 2019

Quantitative reduction in short-chain fatty acids, especially butyrate, contributes to the progression of chronic kidney disease.

Clinical science (London, England : 1979)

Wang S,Lv D,Jiang S,Jiang J,Liang M,Hou F,Chen Y

Fri Sep 13 00:00:00 EDT 2019

Huangqi-Fangfeng protects against allergic airway remodeling through inhibiting epithelial-mesenchymal transition process in mice via regulating epithelial derived TGF-β1.

Phytomedicine : international journal of phytotherapy and phytopharmacology

Yao L,Wang S,Wei P,Bao K,Yuan W,Wang X,Zheng J,Hong M

Fri Nov 01 00:00:00 EDT 2019

Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.

Medical science monitor : international medical journal of experimental and clinical research

Chen H,Liu Y,Jiang CJ,Chen YM,Li H,Liu QA

Wed Jun 05 00:00:00 EDT 2019

Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: Reduction of PPARα.

Biochimie

Bian X,Su X,Wang Y,Zhao G,Zhang B,Li D

Wed May 01 00:00:00 EDT 2019

Electrospinning of in situ crosslinked recombinant human collagen peptide/chitosan nanofibers for wound healing.

Biomaterials science

Deng A,Yang Y,Du S,Yang S

Tue Jul 24 00:00:00 EDT 2018

Electrospinning of in situ crosslinked recombinant human collagen peptide/chitosan nanofibers for wound healing.

Biomaterials science

Deng A,Yang Y,Du S,Yang S

Tue Jul 24 00:00:00 EDT 2018

Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang JR,Lu QB,Feng WB,Wang HP,Tang ZH,Cheng H,Du Q,Wang YB,Li KX,Sun HJ

Fri Jun 01 00:00:00 EDT 2018

Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang JR,Lu QB,Feng WB,Wang HP,Tang ZH,Cheng H,Du Q,Wang YB,Li KX,Sun HJ

Fri Jun 01 00:00:00 EDT 2018

Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang J,Yang A,Wu Y,Guan W,Xiong B,Peng X,Wei X,Chen C,Liu Z

Mon Jan 01 00:00:00 EST 2018

Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Zhang J,Yang A,Wu Y,Guan W,Xiong B,Peng X,Wei X,Chen C,Liu Z

Mon Jan 01 00:00:00 EST 2018

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.

European journal of medicinal chemistry

Li X,Lu C,Liu S,Su C,Xiao T,Bi Z,Sheng P,Huang M,Liu X,Wei Y,Zhao L,Miao S,Mao J,Huang K,Gao S,Liu N,Qi M,Liu T,Qin S,Wei L,Sun T,Ning W,Yang G,Zhou H,Yang C

Wed Sep 05 00:00:00 EDT 2018

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.

European journal of medicinal chemistry

Li X,Lu C,Liu S,Su C,Xiao T,Bi Z,Sheng P,Huang M,Liu X,Wei Y,Zhao L,Miao S,Mao J,Huang K,Gao S,Liu N,Qi M,Liu T,Qin S,Wei L,Sun T,Ning W,Yang G,Zhou H,Yang C

Wed Sep 05 00:00:00 EDT 2018

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.

European journal of medicinal chemistry

Li X,Lu C,Liu S,Su C,Xiao T,Bi Z,Sheng P,Huang M,Liu X,Wei Y,Zhao L,Miao S,Mao J,Huang K,Gao S,Liu N,Qi M,Liu T,Qin S,Wei L,Sun T,Ning W,Yang G,Zhou H,Yang C

Wed Sep 05 00:00:00 EDT 2018

Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway.

European journal of medicinal chemistry

Li X,Lu C,Liu S,Su C,Xiao T,Bi Z,Sheng P,Huang M,Liu X,Wei Y,Zhao L,Miao S,Mao J,Huang K,Gao S,Liu N,Qi M,Liu T,Qin S,Wei L,Sun T,Ning W,Yang G,Zhou H,Yang C

Wed Sep 05 00:00:00 EDT 2018

MKP2 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells through a JNK-dependent pathway.

Clinical science (London, England : 1979)

Li Z,Liu X,Tian F,Li J,Wang Q,Gu C

Thu Nov 15 00:00:00 EST 2018

MKP2 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in renal tubular epithelial cells through a JNK-dependent pathway.

Clinical science (London, England : 1979)

Li Z,Liu X,Tian F,Li J,Wang Q,Gu C

Thu Nov 15 00:00:00 EST 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 EST 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 EST 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 EST 2018

Ginsenoside Rg5 induces apoptosis and autophagy via the inhibition of the PI3K/Akt pathway against breast cancer in a mouse model.

Food & function

Liu Y,Fan D

Wed Nov 14 00:00:00 EST 2018

Azithromycin ameliorates OVA-induced airway remodeling in Balb/c mice via suppression of epithelial-to-mesenchymal transition.

International immunopharmacology

Pu Y,Liu Y,Liao S,Miao S,Zhou L,Wan L

Tue May 01 00:00:00 EDT 2018

Azithromycin ameliorates OVA-induced airway remodeling in Balb/c mice via suppression of epithelial-to-mesenchymal transition.

International immunopharmacology

Pu Y,Liu Y,Liao S,Miao S,Zhou L,Wan L

Tue May 01 00:00:00 EDT 2018

β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.

Journal of molecular medicine (Berlin, Germany)

Xu H,Li Q,Liu J,Zhu J,Li L,Wang Z,Zhang Y,Sun Y,Sun J,Wang R,Yi F

Mon Jan 01 00:00:00 EST 2018

β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.

Journal of molecular medicine (Berlin, Germany)

Xu H,Li Q,Liu J,Zhu J,Li L,Wang Z,Zhang Y,Sun Y,Sun J,Wang R,Yi F

Mon Jan 01 00:00:00 EST 2018

β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.

Journal of molecular medicine (Berlin, Germany)

Xu H,Li Q,Liu J,Zhu J,Li L,Wang Z,Zhang Y,Sun Y,Sun J,Wang R,Yi F

Mon Jan 01 00:00:00 EST 2018

β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.

Journal of molecular medicine (Berlin, Germany)

Xu H,Li Q,Liu J,Zhu J,Li L,Wang Z,Zhang Y,Sun Y,Sun J,Wang R,Yi F

Mon Jan 01 00:00:00 EST 2018

CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway.

Oncology reports

Wang L,Zhang F,Cui JY,Chen L,Chen YT,Liu BW

Tue May 01 00:00:00 EDT 2018

CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway.

Oncology reports

Wang L,Zhang F,Cui JY,Chen L,Chen YT,Liu BW

Tue May 01 00:00:00 EDT 2018

CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway.

Oncology reports

Wang L,Zhang F,Cui JY,Chen L,Chen YT,Liu BW

Tue May 01 00:00:00 EDT 2018

CAFs enhance paclitaxel resistance by inducing EMT through the IL‑6/JAK2/STAT3 pathway.

Oncology reports

Wang L,Zhang F,Cui JY,Chen L,Chen YT,Liu BW

Tue May 01 00:00:00 EDT 2018

S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.

Biochemical and biophysical research communications

Du Y,Zhang W,Liu S,Feng X,Gao F,Liu Q

Mon Sep 03 00:00:00 EDT 2018

S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.

Biochemical and biophysical research communications

Du Y,Zhang W,Liu S,Feng X,Gao F,Liu Q

Mon Sep 03 00:00:00 EDT 2018

Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.

Biochemical and biophysical research communications

Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y

Mon Jan 01 00:00:00 EST 2018

Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.

Biochemical and biophysical research communications

Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y

Mon Jan 01 00:00:00 EST 2018

Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.

Biochemical and biophysical research communications

Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y

Mon Jan 01 00:00:00 EST 2018

Salvianolic acid B inhibits myofibroblast transdifferentiation in experimental pulmonary fibrosis via the up-regulation of Nrf2.

Biochemical and biophysical research communications

Liu M,Xu H,Zhang L,Zhang C,Yang L,Ma E,Liu L,Li Y

Mon Jan 01 00:00:00 EST 2018

MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling.

Oncology letters

You Q,Li H,Liu Y,Xu Y,Miao S,Yao G,Xue Y,Geng J,Jin X,Meng H

Wed Aug 01 00:00:00 EDT 2018

MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling.

Oncology letters

You Q,Li H,Liu Y,Xu Y,Miao S,Yao G,Xue Y,Geng J,Jin X,Meng H

Wed Aug 01 00:00:00 EDT 2018

MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling.

Oncology letters

You Q,Li H,Liu Y,Xu Y,Miao S,Yao G,Xue Y,Geng J,Jin X,Meng H

Wed Aug 01 00:00:00 EDT 2018

MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling.

Oncology letters

You Q,Li H,Liu Y,Xu Y,Miao S,Yao G,Xue Y,Geng J,Jin X,Meng H

Wed Aug 01 00:00:00 EDT 2018

LY2109761 reduces TGF-β1-induced collagen production and contraction in hypertrophic scar fibroblasts.

Archives of dermatological research

Wei G,Xu Q,Liu L,Zhang H,Tan X,Zhang C,Han C,Guo Y,Han G,Zhang C

Mon Oct 01 00:00:00 EDT 2018

LY2109761 reduces TGF-β1-induced collagen production and contraction in hypertrophic scar fibroblasts.

Archives of dermatological research

Wei G,Xu Q,Liu L,Zhang H,Tan X,Zhang C,Han C,Guo Y,Han G,Zhang C

Mon Oct 01 00:00:00 EDT 2018

AMPK/TSC2/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells.

Experimental and therapeutic medicine

Zhan JK,Wang YJ,Li S,Wang Y,Tan P,He JY,Chen YY,Deng HQ,Huang W,Lin X,Liu YS

Sat Dec 01 00:00:00 EST 2018

AMPK/TSC2/mTOR pathway regulates replicative senescence of human vascular smooth muscle cells.

Experimental and therapeutic medicine

Zhan JK,Wang YJ,Li S,Wang Y,Tan P,He JY,Chen YY,Deng HQ,Huang W,Lin X,Liu YS

Sat Dec 01 00:00:00 EST 2018

Expression of Connexin43 in Cerebral Arteries of Patients with Moyamoya Disease.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Liao J,Hong T,Xu J,Zeng E,Tang B,Lai W

Sun Apr 01 00:00:00 EDT 2018

Expression of Connexin43 in Cerebral Arteries of Patients with Moyamoya Disease.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Liao J,Hong T,Xu J,Zeng E,Tang B,Lai W

Sun Apr 01 00:00:00 EDT 2018

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis.

Nature communications

Zeng Z,Li Y,Pan Y,Lan X,Song F,Sun J,Zhou K,Liu X,Ren X,Wang F,Hu J,Zhu X,Yang W,Liao W,Li G,Ding Y,Liang L

Wed Dec 19 00:00:00 EST 2018

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis.

Nature communications

Zeng Z,Li Y,Pan Y,Lan X,Song F,Sun J,Zhou K,Liu X,Ren X,Wang F,Hu J,Zhu X,Yang W,Liao W,Li G,Ding Y,Liang L

Wed Dec 19 00:00:00 EST 2018

Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.

Medical science monitor : international medical journal of experimental and clinical research

Zhao L,Xu Y,Tao L,Yang Y,Shen X,Li L,Luo P

Sun Sep 09 00:00:00 EDT 2018

Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro.

Medical science monitor : international medical journal of experimental and clinical research

Zhao L,Xu Y,Tao L,Yang Y,Shen X,Li L,Luo P

Sun Sep 09 00:00:00 EDT 2018

Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis.

Nature communications

Gao W,Sun Y,Cai M,Zhao Y,Cao W,Liu Z,Cui G,Tang B

Mon Jan 15 00:00:00 EST 2018

Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels.

International journal of nanomedicine

Zhao X,Pan J,Li W,Yang W,Qin L,Pan Y

Tue Dec 11 00:00:00 EST 2018

Gold nanoparticles enhance cisplatin delivery and potentiate chemotherapy by decompressing colorectal cancer vessels.

International journal of nanomedicine

Zhao X,Pan J,Li W,Yang W,Qin L,Pan Y

Tue Dec 11 00:00:00 EST 2018

Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice.

Frontiers in pharmacology

Liu J,Li W,Limbu MH,Li Y,Wang Z,Cheng Z,Zhang X,Chen P

Wed Sep 30 00:00:00 EDT 2020

Effects of Simultaneous Downregulation of PHD1 and Keap1 on Prevention and Reversal of Liver Fibrosis in Mice.

Frontiers in pharmacology

Liu J,Li W,Limbu MH,Li Y,Wang Z,Cheng Z,Zhang X,Chen P

Wed Sep 30 00:00:00 EDT 2020

Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Ren K,Jiang T,Zhou HF,Liang Y,Zhao GJ

Fri Aug 17 00:00:00 EDT 2018

Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Ren K,Jiang T,Zhou HF,Liang Y,Zhao GJ

Fri Aug 17 00:00:00 EDT 2018

Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.

Redox biology

Lu QB,Wan MY,Wang PY,Zhang CX,Xu DY,Liao X,Sun HJ

Sun Apr 01 00:00:00 EDT 2018

Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.

Redox biology

Lu QB,Wan MY,Wang PY,Zhang CX,Xu DY,Liao X,Sun HJ

Sun Apr 01 00:00:00 EDT 2018

Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade.

Redox biology

Lu QB,Wan MY,Wang PY,Zhang CX,Xu DY,Liao X,Sun HJ

Sun Apr 01 00:00:00 EDT 2018

LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.

Oncogene

Zeng K,Chen X,Hu X,Liu X,Xu T,Sun H,Pan Y,He B,Wang S

Mon Oct 01 00:00:00 EDT 2018

LACTB, a novel epigenetic silenced tumor suppressor, inhibits colorectal cancer progression by attenuating MDM2-mediated p53 ubiquitination and degradation.

Oncogene

Zeng K,Chen X,Hu X,Liu X,Xu T,Sun H,Pan Y,He B,Wang S

Mon Oct 01 00:00:00 EDT 2018

Renal Denervation Effects on Myocardial Fibrosis and Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zhang B,Li X,Chen C,Jiang W,Lu D,Liu Q,Wang K,Yan Y,Jiang Z,Geng J,Xu H,Shan Q

Fri Aug 17 00:00:00 EDT 2018

Renal Denervation Effects on Myocardial Fibrosis and Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Zhang B,Li X,Chen C,Jiang W,Lu D,Liu Q,Wang K,Yan Y,Jiang Z,Geng J,Xu H,Shan Q

Fri Aug 17 00:00:00 EDT 2018

Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Wu F,Hao Y,Yang J,Yao W,Xu Y,Yan L,Niu Y,Sun T,Yu J,Zhou R

Mon May 01 00:00:00 EDT 2017

Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Wu F,Hao Y,Yang J,Yao W,Xu Y,Yan L,Niu Y,Sun T,Yu J,Zhou R

Mon May 01 00:00:00 EDT 2017

Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver.

Biochimica et biophysica acta. Molecular basis of disease

Bian EB,Wang YY,Yang Y,Wu BM,Xu T,Meng XM,Huang C,Zhang L,Lv XW,Xiong ZG,Li J

Wed Mar 01 00:00:00 EST 2017

Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver.

Biochimica et biophysica acta. Molecular basis of disease

Bian EB,Wang YY,Yang Y,Wu BM,Xu T,Meng XM,Huang C,Zhang L,Lv XW,Xiong ZG,Li J

Wed Mar 01 00:00:00 EST 2017

Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells.

International journal of molecular medicine

Zhu YC,Wang YK,Bai SJ,Zha FF,Feng G,Gao CP,Liu J

Sun Oct 01 00:00:00 EDT 2017

Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells.

International journal of molecular medicine

Zhu YC,Wang YK,Bai SJ,Zha FF,Feng G,Gao CP,Liu J

Sun Oct 01 00:00:00 EDT 2017

Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.

The journal of sexual medicine

Chen F,Zhang H,Wang Z,Ding W,Zeng Q,Liu W,Huang C,He S,Wei A

Fri Sep 01 00:00:00 EDT 2017

Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.

The journal of sexual medicine

Chen F,Zhang H,Wang Z,Ding W,Zeng Q,Liu W,Huang C,He S,Wei A

Fri Sep 01 00:00:00 EDT 2017

Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.

The journal of sexual medicine

Chen F,Zhang H,Wang Z,Ding W,Zeng Q,Liu W,Huang C,He S,Wei A

Fri Sep 01 00:00:00 EDT 2017

Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.

The journal of sexual medicine

Chen F,Zhang H,Wang Z,Ding W,Zeng Q,Liu W,Huang C,He S,Wei A

Fri Sep 01 00:00:00 EDT 2017

Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes.

The journal of sexual medicine

Chen F,Zhang H,Wang Z,Ding W,Zeng Q,Liu W,Huang C,He S,Wei A

Fri Sep 01 00:00:00 EDT 2017

Exenatide Inhibits the K_Ca3.1 Channels of Aortic Vascular Smooth Muscle in Diabetic Rats.

Acta Cardiologica Sinica

Dong P,Liu M,Liu C

Wed Nov 01 00:00:00 EDT 2017

Exenatide Inhibits the K_Ca3.1 Channels of Aortic Vascular Smooth Muscle in Diabetic Rats.

Acta Cardiologica Sinica

Dong P,Liu M,Liu C

Wed Nov 01 00:00:00 EDT 2017

Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.

Journal of the American Society of Hypertension : JASH

Luo H,Liu B,Zhao L,He J,Li T,Zha L,Li X,Qi Q,Liu Y,Yu Z

Sun Oct 01 00:00:00 EDT 2017

Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.

Journal of the American Society of Hypertension : JASH

Luo H,Liu B,Zhao L,He J,Li T,Zha L,Li X,Qi Q,Liu Y,Yu Z

Sun Oct 01 00:00:00 EDT 2017

Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.

Journal of the American Society of Hypertension : JASH

Luo H,Liu B,Zhao L,He J,Li T,Zha L,Li X,Qi Q,Liu Y,Yu Z

Sun Oct 01 00:00:00 EDT 2017

Galectin-3 mediates pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension.

Journal of the American Society of Hypertension : JASH

Luo H,Liu B,Zhao L,He J,Li T,Zha L,Li X,Qi Q,Liu Y,Yu Z

Sun Oct 01 00:00:00 EDT 2017

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.

Journal of the American Heart Association

Yao Y,Hu Z,Ye J,Hu C,Song Q,Da X,Yu Y,Li H,Xu C,Chen Q,Wang QK

Sun Jun 25 00:00:00 EDT 2017

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.

Journal of the American Heart Association

Yao Y,Hu Z,Ye J,Hu C,Song Q,Da X,Yu Y,Li H,Xu C,Chen Q,Wang QK

Sun Jun 25 00:00:00 EDT 2017

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.

Journal of the American Heart Association

Yao Y,Hu Z,Ye J,Hu C,Song Q,Da X,Yu Y,Li H,Xu C,Chen Q,Wang QK

Sun Jun 25 00:00:00 EDT 2017

Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury.

Journal of the American Heart Association

Yao Y,Hu Z,Ye J,Hu C,Song Q,Da X,Yu Y,Li H,Xu C,Chen Q,Wang QK

Sun Jun 25 00:00:00 EDT 2017

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling.

Scientific reports

Wang L,Hu L,Zhou X,Xiong Z,Zhang C,Shehada HMA,Hu B,Song J,Chen L

Tue Oct 17 00:00:00 EDT 2017

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling.

Scientific reports

Wang L,Hu L,Zhou X,Xiong Z,Zhang C,Shehada HMA,Hu B,Song J,Chen L

Tue Oct 17 00:00:00 EDT 2017

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling.

Scientific reports

Wang L,Hu L,Zhou X,Xiong Z,Zhang C,Shehada HMA,Hu B,Song J,Chen L

Tue Oct 17 00:00:00 EDT 2017

Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling.

Scientific reports

Wang L,Hu L,Zhou X,Xiong Z,Zhang C,Shehada HMA,Hu B,Song J,Chen L

Tue Oct 17 00:00:00 EDT 2017

CAPE-pNO₂ ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.

Oncotarget

Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z

Fri Dec 29 00:00:00 EST 2017

CAPE-pNO₂ ameliorated diabetic nephropathy through regulating the Akt/NF-κB/ iNOS pathway in STZ-induced diabetic mice.

Oncotarget

Wang X,Li D,Fan L,Xiao Q,Zuo H,Li Z

Fri Dec 29 00:00:00 EST 2017

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.

Scientific reports

Wu L,Zhang Q,Mo W,Feng J,Li S,Li J,Liu T,Xu S,Wang W,Lu X,Yu Q,Chen K,Xia Y,Lu J,Xu L,Zhou Y,Fan X,Guo C

Thu Aug 24 00:00:00 EDT 2017

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.

Scientific reports

Wu L,Zhang Q,Mo W,Feng J,Li S,Li J,Liu T,Xu S,Wang W,Lu X,Yu Q,Chen K,Xia Y,Lu J,Xu L,Zhou Y,Fan X,Guo C

Thu Aug 24 00:00:00 EDT 2017

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.

Scientific reports

Wu L,Zhang Q,Mo W,Feng J,Li S,Li J,Liu T,Xu S,Wang W,Lu X,Yu Q,Chen K,Xia Y,Lu J,Xu L,Zhou Y,Fan X,Guo C

Thu Aug 24 00:00:00 EDT 2017

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways.

Scientific reports

Wu L,Zhang Q,Mo W,Feng J,Li S,Li J,Liu T,Xu S,Wang W,Lu X,Yu Q,Chen K,Xia Y,Lu J,Xu L,Zhou Y,Fan X,Guo C

Thu Aug 24 00:00:00 EDT 2017

Synergistic cardioprotective effects of rAAV9-CyclinA2 combined with fibrin glue in rats after myocardial infarction.

Journal of molecular histology

Cao W,Chang YF,Zhao AC,Chen BD,Liu F,Ma YT,Ma X

Tue Aug 01 00:00:00 EDT 2017

Pulmonary inflammatory myofibroblastic tumor versus IgG4-related inflammatory pseudotumor: differential diagnosis based on a case series.

Journal of thoracic disease

Zhu L,Li J,Liu C,Ding W,Lin F,Guo C,Liu L

Wed Mar 01 00:00:00 EST 2017

Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression.

Biomaterials

Zhao X,Jiang S,Liu S,Chen S,Lin ZY,Pan G,He F,Li F,Fan C,Cui W

Sat Aug 01 00:00:00 EDT 2015

Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression.

Biomaterials

Zhao X,Jiang S,Liu S,Chen S,Lin ZY,Pan G,He F,Li F,Fan C,Cui W

Sat Aug 01 00:00:00 EDT 2015

Angiotensin II as a morphogenic cytokine stimulating fibrogenesis of human tenon's capsule fibroblasts.

Investigative ophthalmology & visual science

Shi H,Zhang Y,Fu S,Lu Z,Ye W,Xiao Y

Tue Jan 06 00:00:00 EST 2015

Angiotensin II as a morphogenic cytokine stimulating fibrogenesis of human tenon's capsule fibroblasts.

Investigative ophthalmology & visual science

Shi H,Zhang Y,Fu S,Lu Z,Ye W,Xiao Y

Tue Jan 06 00:00:00 EST 2015

5-Aminolevulinic Acid-Mediated Sonodynamic Therapy Promotes Phenotypic Switching from Dedifferentiated to Differentiated Phenotype via Reactive Oxygen Species and p38 Mitogen-Activated Protein Kinase in Vascular Smooth Muscle Cells.

Ultrasound in medicine & biology

Dan J,Sun X,Li W,Zhang Y,Li X,Xu H,Li Z,Tian Z,Guo S,Yao J,Gao W,Tian Y

Mon Jun 01 00:00:00 EDT 2015

Ultrasound in medicine & biology

Dan J,Sun X,Li W,Zhang Y,Li X,Xu H,Li Z,Tian Z,Guo S,Yao J,Gao W,Tian Y

Mon Jun 01 00:00:00 EDT 2015

MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study.

Biochemical and biophysical research communications

Lu L,Wang J,Lu H,Zhang G,Liu Y,Wang J,Zhang Y,Shang H,Ji H,Chen X,Duan Y,Li Y

Fri Sep 25 00:00:00 EDT 2015

MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study.

Biochemical and biophysical research communications

Lu L,Wang J,Lu H,Zhang G,Liu Y,Wang J,Zhang Y,Shang H,Ji H,Chen X,Duan Y,Li Y

Fri Sep 25 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: Actin Alpha 2 Smooth Muscle Aorta; Actin Vascular Smooth Muscle; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; Alpha Cardiac Actin; Alpha-actin-2; alpha-cardiac actin; Aortic Smooth Muscle; asma; Cell growth-inhibiting gene 46 protein; Growth Inhibiting Gene 46; smooth muscle; smooth muscle alpha-actin

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Gene Aliases: 0610041G09Rik; a-SMA; AAT6; ACTA2; ACTSA; ACTVS; alphaSMA; GIG46; MYMY5; SMalphaA

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UniProt ID: (Human) P62736, (Rat) P62738, (Mouse) P62737

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Entrez Gene ID: (Human) 59, (Rat) 81633, (Mouse) 11475

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Function(s)

ATP binding protein kinase binding nucleotide binding protein binding actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein

Process(es)

muscle contraction regulation of blood pressure response to virus positive regulation of gene expression vascular smooth muscle contraction glomerular mesangial cell development mesenchyme migration

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Alpha SMA Polyclonal Antibody

Alpha SMA Antibody (55135-1-AP) in IHC (P)

Product Details

55135-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

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Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

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Product Specific Information

Target Information

Bioinformatics

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