Product References
Derrone Targeting the TGF Type 1 Receptor Kinase Improves Bleomycin-Mediated Pulmonary Fibrosis through Inhibition of Smad Signaling Pathway.
International journal of molecular sciences
Molagoda IMN,Sanjaya SS,Lee KT,Choi YH,Lee JH,Lee MH,Kang CH,Lee CM,Kim GY
14-9760-82 was used in Immunocytochemistry to investigate whether derrone promotes anti-fibrotic effects on TGF-β1-stimulated MRC-5 lung fibroblast cells and bleomycin-induced lung fibrosis.
Fri Apr 14 00:00:00 EDT 2023
Sialin mediates submandibular gland regeneration ability by affecting polysialic acid synthesis.
Oral diseases
Wang B,Li Z,Li J,Shao Q,Qin L
14-9760-82 was used in Immunohistochemistry to indicate that sialin was vital for submandibular gland regeneration which mediated the process of gland regeneration by affecting the polysialic acid synthesis.
Sat Jul 01 00:00:00 EDT 2023
Development of Neovasculature in Axially Vascularized Calcium Phosphate Cement Scaffolds.
Journal of functional biomaterials
Ouhaddi Y,Charbonnier B,Porge J,Zhang YL,Garcia I,Gbureck U,Grover L,Gilardino M,Harvey E,Makhoul N,Barralet J
14-9760-82 was used in Immunohistochemistry to investigate if sprouting was a general response to surgical injury or placement of an inorganic construct around the vessel.
Tue Feb 14 00:00:00 EST 2023
JAK-STAT Signaling in Inflammatory Breast Cancer Enables Chemotherapy-Resistant Cell States.
Cancer research
Stevens LE,Peluffo G,Qiu X,Temko D,Fassl A,Li Z,Trinh A,Seehawer M,Jovanović B,Alečković M,Wilde CM,Geck RC,Shu S,Kingston NL,Harper NW,Almendro V,Pyke AL,Egri SB,Papanastasiou M,Clement K,Zhou N,Walker S,Salas J,Park SY,Frank DA,Meissner A,Jaffe JD,Sicinski P,Toker A,Michor F,Long HW,Overmoyer BA,Polyak K
14-9760-82 was used in Immunohistochemistry-immunofluorescence to report that CD44+CD24- cells are the most frequent cell type in inflammatory breast cancer (IBC) and are commonly pSTAT3+.
Wed Jan 18 00:00:00 EST 2023
4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration.
Biomedicines
Jagadeeshaprasad MG,Govindappa PK,Nelson AM,Noble MD,Elfar JC
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to discover that 4-aminopyridine causes faster wound closure, restoration of normal-appearing skin architecture, and reinnervation.
Fri Jul 08 00:00:00 EDT 2022
4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration.
Biomedicines
Jagadeeshaprasad MG,Govindappa PK,Nelson AM,Noble MD,Elfar JC
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to discover that 4-aminopyridine causes faster wound closure, restoration of normal-appearing skin architecture, and reinnervation.
Fri Jul 08 00:00:00 EDT 2022
Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma.
Nature communications
Rebbeck CA,Xian J,Bornelöv S,Geradts J,Hobeika A,Geiger H,Alvarez JF,Rozhkova E,Nicholls A,Robine N,Lyerly HK,Hannon GJ
14-9760-82 was used in Mass Cytometry to identify early processes and potential biomarkers, including CAMK2N1, MNX1, ADCY5, HOXC11 and ANKRD22, whose reduced expression is associated with the progression of DCIS to invasive breast cancer.
Mon Jun 13 00:00:00 EDT 2022
Modeling long QT syndrome type 2 on-a-chip via in-depth assessment of isogenic gene-edited 3D cardiac tissues.
Science advances
Veldhuizen J,Mann HF,Karamanova N,Van Horn WD,Migrino RQ,Brafman D,Nikkhah M
14-9760-82 was used in Immunohistochemistry-immunofluorescence to develop a LQTS2-diseased tissue-on-a-chip model, using 3D coculture of isogenic stem cell-derived cardiomyocytes (CMs) and cardiac fibroblasts (CFs) within an organotypic microfluidic chip technology.
Fri Dec 16 00:00:00 EST 2022
Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis.
Autophagy
Liu J,Li S,Fei X,Nan X,Shen Y,Xiu H,Cormier SA,Lu C,Guo C,Wang S,Cai Z,Wang P
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to demonstrate the central role of PM-induced neutrophil recruitment in promoting lung cancer metastasis.
Sun May 01 00:00:00 EDT 2022
The p-STAT3/ANXA2 axis promotes caspase-1-mediated hepatocyte pyroptosis in non-alcoholic steatohepatitis.
Journal of translational medicine
Feng Y,Li W,Wang Z,Zhang R,Li Y,Zang L,Wang P,Li Z,Dong Y
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to explore the roles of Annexin A2 (ANXA2) on hepatocyte pyroptosis and hepatic fibrosis in nonalcoholic steatohepatitis (NASH) and underlying molecular mechanism.
Wed Nov 02 00:00:00 EDT 2022
Modeling ascending Ureaplasma parvum infection through the female reproductive tract using vagina-cervix-decidua-organ-on-a-chip and feto-maternal interface-organ-on-a-chip.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Tantengco OAG,Richardson LS,Radnaa E,Kammala AK,Kim S,Medina PMB,Han A,Menon R
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to report the colonization of U. parvum in various cell types; however, inconsistent, and low-grade inflammation across multiple cell types suggests poor immunogenicity induced by U. parvum.
Sat Oct 01 00:00:00 EDT 2022
Fully Reduced HMGB1-Containing Peptide-Based Polyurethane Scaffold with Minimal Functional Unit of Skin (MFUS) Enhances Large and Deep Wounded Skin Healing.
Macromolecular bioscience
Chang P,Li S,Sun Q,Guo K,Wang H,Li S,Zhang L,Xie Y,Zheng X,Liu Y
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to demonstrate that the combination of fully reduced HMGB1-LDI-Gly polymer with MFUS provides a new tissue engineering approach for large full-thickness skin wound healing.
Tue Feb 01 00:00:00 EST 2022
Integrated Analytical System for Clinical Single-Cell Analysis.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Peterson HM,Chin LK,Iwamoto Y,Oh J,Carlson JCT,Lee H,Im H,Weissleder R
14-9760-82 was used in Immunohistochemistry-immunofluorescence to report an inexpensive, robust, multichannel singlecell imaging system (i2SCAN) which can expand profiling capabilities in the clinic.
Fri Jul 01 00:00:00 EDT 2022
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity.
Nature immunology
Prados A,Onder L,Cheng HW,Mörbe U,Lütge M,Gil-Cruz C,Perez-Shibayama C,Koliaraki V,Ludewig B,Kollias G
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2021
Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease.
Hepatology international
Xu Y,Wang N,Tan HY,Li S,Zhang C,Feng Y
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Thu Apr 01 00:00:00 EDT 2021
A multilayered scaffold for regeneration of smooth muscle and connective tissue layers.
Journal of biomedical materials research. Part A
Garrison CM,Singh-Varma A,Pastino AK,Steele JAM,Kohn J,Murthy NS,Schwarzbauer JE
14-9760-82 was used in Immunocytochemistry to demonstrate if differently-oriented scaffold fibers direct cell and extracellular matrix (ECM) organisation, and if scaffold fibers and extracellular matrix protein networks are maintained after decellularization.
Sat May 01 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Tue May 18 00:00:00 EDT 2021
Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production.
Frontiers in pharmacology
El-Sherbiny M,Atef H,Eladl MA,Mohamed AS,El-Shafey M,Ali HS,Zaitone SA,Alomar SY,Alqahtani SAM,Aloyouni SY,Attia MA
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Tue May 18 00:00:00 EDT 2021
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Cell death & disease
Zhang L,He J,Wang J,Liu J,Chen Z,Deng B,Wei L,Wu H,Liang B,Li H,Huang Y,Lu L,Yang Z,Xian S,Wang L
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy.
Cell death & disease
Zhang L,He J,Wang J,Liu J,Chen Z,Deng B,Wei L,Wu H,Liang B,Li H,Huang Y,Lu L,Yang Z,Xian S,Wang L
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Tue May 11 00:00:00 EDT 2021
Chrysin Ameliorates Cyclosporine-A-Induced Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial-Mesenchymal Transition.
International journal of molecular sciences
Nagavally RR,Sunilkumar S,Akhtar M,Trombetta LD,Ford SM
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Western Blot
Thu Sep 23 00:00:00 EDT 2021
The KLB rs17618244 gene variant is associated with fibrosing MAFLD by promoting hepatic stellate cell activation.
EBioMedicine
Panera N,Meroni M,Longo M,Crudele A,Valenti L,Bellacchio E,Miele L,D'Oria V,Paolini E,Maggioni M,Fracanzani AL,Alisi A,Dongiovanni P
14-9760-82 was used in Immunocytochemistry to reveal a signaling pathway wherein leptin modulates NMDARs via Src to regulate β-cell excitability and suggests NMDARs as a potential target to overcome leptin resistance.
Mon Mar 01 00:00:00 EST 2021
The KLB rs17618244 gene variant is associated with fibrosing MAFLD by promoting hepatic stellate cell activation.
EBioMedicine
Panera N,Meroni M,Longo M,Crudele A,Valenti L,Bellacchio E,Miele L,D'Oria V,Paolini E,Maggioni M,Fracanzani AL,Alisi A,Dongiovanni P
14-9760-82 was used in Immunocytochemistry to reveal a signaling pathway wherein leptin modulates NMDARs via Src to regulate β-cell excitability and suggests NMDARs as a potential target to overcome leptin resistance.
Mon Mar 01 00:00:00 EST 2021
Macrophages Modulate the Function of MSC- and iPSC-Derived Fibroblasts in the Presence of Polyethylene Particles.
International journal of molecular sciences
Gao Q,Li Z,Rhee C,Xiang S,Maruyama M,Huang EE,Yao Z,Bunnell BA,Tuan RS,Lin H,Gold MS,Goodman SB
14-9760-82 was used in Immunohistochemistry to examine immune cell interactions in a 3D model simulating pathophysiological disease-specific microenvironment.
Sat Nov 27 00:00:00 EST 2021
Human Mesenchymal Stromal Cell-Derived Exosomes Promote In Vitro Wound Healing by Modulating the Biological Properties of Skin Keratinocytes and Fibroblasts and Stimulating Angiogenesis.
International journal of molecular sciences
Tutuianu R,Rosca AM,Iacomi DM,Simionescu M,Titorencu I
14-9760-82 was used in Western Blotting and Immunocytochemsitry to test if MSC-derived exosomes could accelerate wound healing by enhancing the biological properties of the main cell types involved in the key phases of this process.
Wed Jun 09 00:00:00 EDT 2021
Human Mesenchymal Stromal Cell-Derived Exosomes Promote In Vitro Wound Healing by Modulating the Biological Properties of Skin Keratinocytes and Fibroblasts and Stimulating Angiogenesis.
International journal of molecular sciences
Tutuianu R,Rosca AM,Iacomi DM,Simionescu M,Titorencu I
14-9760-82 was used in Western Blotting and Immunocytochemsitry to test if MSC-derived exosomes could accelerate wound healing by enhancing the biological properties of the main cell types involved in the key phases of this process.
Wed Jun 09 00:00:00 EDT 2021
Dephosphorylation of Caveolin-1 Controls C-X-C Motif Chemokine Ligand 10 Secretion in Mesenchymal Stem Cells to Regulate the Process of Wound Healing.
Frontiers in cell and developmental biology
Wang P,Zhao Y,Wang J,Wu Z,Sui B,Mao X,Shi S,Kou X
14-9760-82 was used in Immunohistochemistr and Western Blotting to establish a role of p-Cav-1 in controlling cytokine release of MSC and may present a potential therapeutic approach for promoting scarless wound healing.
Fri Nov 19 00:00:00 EST 2021
Dephosphorylation of Caveolin-1 Controls C-X-C Motif Chemokine Ligand 10 Secretion in Mesenchymal Stem Cells to Regulate the Process of Wound Healing.
Frontiers in cell and developmental biology
Wang P,Zhao Y,Wang J,Wu Z,Sui B,Mao X,Shi S,Kou X
14-9760-82 was used in Immunohistochemistr and Western Blotting to establish a role of p-Cav-1 in controlling cytokine release of MSC and may present a potential therapeutic approach for promoting scarless wound healing.
Fri Nov 19 00:00:00 EST 2021
Dephosphorylation of Caveolin-1 Controls C-X-C Motif Chemokine Ligand 10 Secretion in Mesenchymal Stem Cells to Regulate the Process of Wound Healing.
Frontiers in cell and developmental biology
Wang P,Zhao Y,Wang J,Wu Z,Sui B,Mao X,Shi S,Kou X
14-9760-82 was used in Immunohistochemistr and Western Blotting to establish a role of p-Cav-1 in controlling cytokine release of MSC and may present a potential therapeutic approach for promoting scarless wound healing.
Fri Nov 19 00:00:00 EST 2021
Dephosphorylation of Caveolin-1 Controls C-X-C Motif Chemokine Ligand 10 Secretion in Mesenchymal Stem Cells to Regulate the Process of Wound Healing.
Frontiers in cell and developmental biology
Wang P,Zhao Y,Wang J,Wu Z,Sui B,Mao X,Shi S,Kou X
14-9760-82 was used in Immunohistochemistr and Western Blotting to establish a role of p-Cav-1 in controlling cytokine release of MSC and may present a potential therapeutic approach for promoting scarless wound healing.
Fri Nov 19 00:00:00 EST 2021
Microvesicles and exosomes released by amnion epithelial cells under oxidative stress cause inflammatory changes in uterine cells†.
Biology of reproduction
Shahin HI,Radnaa E,Tantengco OAG,Kechichian T,Kammala AK,Sheller-Miller S,Taylor BD,Menon R
14-9760-82 was used in Immunocytochemistry-immunofluorescence to suggest that fetal-derived exosomes and microvesicles under oxidative stress exhibited distinct characteristics and a synergistic inflammatory role in uterine cells associated with the initiation of parturition.
Tue Aug 03 00:00:00 EDT 2021
An in vitro tumorigenesis model based on live-cell-generated oxygen and nutrient gradients.
Communications biology
Gilmore AC,Flaherty SJ,Somasundaram V,Scheiblin DA,Lockett SJ,Wink DA,Heinz WF
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Thu Apr 15 00:00:00 EDT 2021
Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation.
Journal of thrombosis and haemostasis : JTH
Suess PM,Smith SA,Morrissey JH
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to indicate that platelet-derived polyphosphate acts as a cell signaling molecule by inducing murine and human fibroblasts to differentiate into myofibroblasts, a cell type known to drive both wound healing and fibrosing diseases.
Sun Nov 01 00:00:00 EDT 2020
Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation.
Journal of thrombosis and haemostasis : JTH
Suess PM,Smith SA,Morrissey JH
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to indicate that platelet-derived polyphosphate acts as a cell signaling molecule by inducing murine and human fibroblasts to differentiate into myofibroblasts, a cell type known to drive both wound healing and fibrosing diseases.
Sun Nov 01 00:00:00 EDT 2020
Platelet polyphosphate induces fibroblast chemotaxis and myofibroblast differentiation.
Journal of thrombosis and haemostasis : JTH
Suess PM,Smith SA,Morrissey JH
14-9760-82 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to indicate that platelet-derived polyphosphate acts as a cell signaling molecule by inducing murine and human fibroblasts to differentiate into myofibroblasts, a cell type known to drive both wound healing and fibrosing diseases.
Sun Nov 01 00:00:00 EDT 2020
Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype.
Frontiers in cardiovascular medicine
Gonzalez BA,Perez-Nevarez M,Mirza A,Perez MG,Lin YM,Hsu CD,Caobi A,Raymond A,Gomez Hernandez ME,Fernandez-Lima F,George F,Ramaswamy S
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Mon Sep 28 00:00:00 EDT 2020
Physiologically Relevant Fluid-Induced Oscillatory Shear Stress Stimulation of Mesenchymal Stem Cells Enhances the Engineered Valve Matrix Phenotype.
Frontiers in cardiovascular medicine
Gonzalez BA,Perez-Nevarez M,Mirza A,Perez MG,Lin YM,Hsu CD,Caobi A,Raymond A,Gomez Hernandez ME,Fernandez-Lima F,George F,Ramaswamy S
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Mon Sep 28 00:00:00 EDT 2020
Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus.
Cancer biology & therapy
Wang T,Xie S,Luo R,Shi L,Bai P,Wang X,Wan R,Deng J,Wu Z,Li W,Xiao W,Wang Y,Chen B,Zhang K,Xing J
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Mon Mar 29 00:00:00 EDT 2021
Two novel TSC2 mutations in renal epithelioid angiomyolipoma sensitive to everolimus.
Cancer biology & therapy
Wang T,Xie S,Luo R,Shi L,Bai P,Wang X,Wan R,Deng J,Wu Z,Li W,Xiao W,Wang Y,Chen B,Zhang K,Xing J
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Mon Mar 29 00:00:00 EDT 2021
Low Incidence of High-Grade Pancreatic Intraepithelial Neoplasia Lesions in a Crmp4 Gene-Deficient Mouse Model of Pancreatic Cancer.
Translational oncology
Yazawa K,Nakamura F,Masukawa D,Sato S,Hiroshima Y,Yabushita Y,Mori R,Matsuyama R,Kato I,Taniguchi H,Goshima Y,Endo I
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Sun Mar 01 00:00:00 EST 2020
miR-135a Alleviates Silica-Induced Pulmonary Fibrosis by Targeting NF-κB/Inflammatory Signaling Pathway.
Mediators of inflammation
Xie B,Lu C,Chen C,Zhou J,Deng Z
14-9760 was used in Immunohistochemistry-immunofluorescence to investigate the roles and mechanisms of miR-135a underlying silica-induced pulmonary fibrosis.
Mon Jun 07 00:00:00 EDT 2021
miR-135a Alleviates Silica-Induced Pulmonary Fibrosis by Targeting NF-κB/Inflammatory Signaling Pathway.
Mediators of inflammation
Xie B,Lu C,Chen C,Zhou J,Deng Z
14-9760 was used in Immunohistochemistry-immunofluorescence to investigate the roles and mechanisms of miR-135a underlying silica-induced pulmonary fibrosis.
Mon Jun 07 00:00:00 EDT 2021
Differential effects of low-dose sacubitril and/or valsartan on renal disease in salt-sensitive hypertension.
American journal of physiology. Renal physiology
Polina I,Domondon M,Fox R,Sudarikova AV,Troncoso M,Vasileva VY,Kashyrina Y,Gooz MB,Schibalski RS,DeLeon-Pennell KY,Fitzgibbon WR,Ilatovskaya DV
14-9760-82 was used in Western Blot to investigate if increasing atrial natriuretic peptide levels with sacubitril, combined with renin-angiotensin system blockage by valsartan, can be beneficial for alleviation of renal damage in a model of salt-sensitive hypertension.
Wed Jul 01 00:00:00 EDT 2020
Hyperion imaging system reveals heterogeneous tumor microenvironment of oral squamous cell carcinoma patients at T1N0M0 stage.
Annals of translational medicine
Xie S,Shan XF,Yau V,Zhang JY,Zhang XY,Yan YP,Cai ZG
14-9760 was used in Immunocytochemistry-immunoflourescence to identify heterogeneity in the tumour microenvironment of oral squamous cell carcinoma T1N0M0 samples which may contribute to poor early prognosis.
Sun Nov 01 00:00:00 EDT 2020
A new intrasurgical technique to safely and reproducibly induce partial unilateral urinary obstruction and renal scarring in a Rat Model.
International urology and nephrology
Vroomen LGPH,John NT,Fuijmori M,Sivaraman A,Felsen D,Srimathveeravalli G
14-9760-82 was used in Immunohistochemistry to evaluate whether irreversible electroporation can be used to induce urinary obstruction for a rat model of renal scarring.
Wed Jul 01 00:00:00 EDT 2020
A Novel Model of Balloon Angioplasty Injury in Rat Arteriovenous Fistula.
Journal of vascular research
Somarathna M,Isayeva-Waldrop T,Al-Balas A,Guo L,Lee T
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Mon Sep 14 00:00:00 EDT 2020
A Novel Model of Balloon Angioplasty Injury in Rat Arteriovenous Fistula.
Journal of vascular research
Somarathna M,Isayeva-Waldrop T,Al-Balas A,Guo L,Lee T
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Mon Sep 14 00:00:00 EDT 2020
Derivation of induced pluripotent stem cells (SDUKIi003-A) from a 20-year-old male patient diagnosed with Asperger syndrome.
Stem cell research
Kamand M,Ilieva M,Louise Forsberg S,Thomassen M,Meyer M,Fex Svenningsen Å,Maria Michel T
14-9760-82 was used in In vitro Assay to validate the expression of pluripotency markers, differentiation into the three germ layers, and absence of chromosomal abnormalities.
Thu Oct 01 00:00:00 EDT 2020
Generation of human induced pluripotent stem cells (SDUKIi002-A) from a 22-year-old male diagnosed with autism spectrum disorder.
Stem cell research
Kamand M,Ilieva M,Forsberg SL,Thomassen M,Fex Svenningsen Å,Holst B,Meyer M,Michel TM
14-9760-82 was used in Immunocytochemistry to create and characterise a human-induced pluripotent stem cell line (SDUKIi002-A) from a 22-year old autistic male identified in the "FYNEN-cohort" of Southern Denmark.
Wed Jul 01 00:00:00 EDT 2020
Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro.
International journal of cell biology
Polley A,Khanam R,Sengupta A,Chakraborty S
14-9760 was used in Immunocytochemistry-immunoflourescence to study the Asporin function in aortic cusp mineralization and calcification.
Mon Sep 28 00:00:00 EDT 2020
Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro.
International journal of cell biology
Polley A,Khanam R,Sengupta A,Chakraborty S
14-9760 was used in Immunocytochemistry-immunoflourescence to study the Asporin function in aortic cusp mineralization and calcification.
Mon Sep 28 00:00:00 EDT 2020
Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis.
JCI insight
Lu S,Jolly AJ,Strand KA,Dubner AM,Mutryn MF,Moulton KS,Nemenoff RA,Majesky MW,Weiser-Evans MC
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Thu Dec 03 00:00:00 EST 2020
Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction.
PloS one
Gilles G,McCulloch AD,Brakebusch CH,Herum KM
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Mon Dec 21 00:00:00 EST 2020
Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction.
PloS one
Gilles G,McCulloch AD,Brakebusch CH,Herum KM
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Mon Dec 21 00:00:00 EST 2020
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity.
Scientific reports
Gorchs L,Ahmed S,Mayer C,Knauf A,Fernández Moro C,Svensson M,Heuchel R,Rangelova E,Bergman P,Kaipe H
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Thu Oct 15 00:00:00 EDT 2020
The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity.
Scientific reports
Gorchs L,Ahmed S,Mayer C,Knauf A,Fernández Moro C,Svensson M,Heuchel R,Rangelova E,Bergman P,Kaipe H
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Thu Oct 15 00:00:00 EDT 2020
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome.
eLife
Bersini S,Schulte R,Huang L,Tsai H,Hetzer MW
14-9760 was used in Immunohistochemistry-immunofluorescence to show that iVECs and iSMCs retain disease-related signatures, allowing modeling of vascular aging and HGPS in vitro.
Tue Sep 08 00:00:00 EDT 2020
Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome.
eLife
Bersini S,Schulte R,Huang L,Tsai H,Hetzer MW
14-9760 was used in Immunohistochemistry-immunofluorescence to show that iVECs and iSMCs retain disease-related signatures, allowing modeling of vascular aging and HGPS in vitro.
Tue Sep 08 00:00:00 EDT 2020
Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus.
Scientific reports
Cozart MA,Phelan KD,Wu H,Mu S,Birnbaumer L,Rusch NJ,Zheng F
14-9760 was used in Immunohistochemistry to show ablation of smooth muscle transient receptor potential 3 channels eliminates the secondary phase of intense seizures, consequently reducing the duration of status epilepticus.
Tue Jan 21 00:00:00 EST 2020
Vascular smooth muscle TRPC3 channels facilitate the inverse hemodynamic response during status epilepticus.
Scientific reports
Cozart MA,Phelan KD,Wu H,Mu S,Birnbaumer L,Rusch NJ,Zheng F
14-9760 was used in Immunohistochemistry to show ablation of smooth muscle transient receptor potential 3 channels eliminates the secondary phase of intense seizures, consequently reducing the duration of status epilepticus.
Tue Jan 21 00:00:00 EST 2020
A mouse model of stenosis distal to an arteriovenous fistula recapitulates human central venous stenosis.
JVS-vascular science
Taniguchi R,Ono S,Isaji T,Gorecka J,Lee SR,Matsubara Y,Yatsula B,Koizumi J,Nishibe T,Hoshina K,Dardik A
14-9760-82 was used in Immunohistochemistry to understand mechanisms underlying arteriovenous fistula failure owing to central venous stenosis.
Wed Apr 20 00:00:00 EDT 2022
A mouse model of stenosis distal to an arteriovenous fistula recapitulates human central venous stenosis.
JVS-vascular science
Taniguchi R,Ono S,Isaji T,Gorecka J,Lee SR,Matsubara Y,Yatsula B,Koizumi J,Nishibe T,Hoshina K,Dardik A
14-9760-82 was used in Immunohistochemistry to understand mechanisms underlying arteriovenous fistula failure owing to central venous stenosis.
Wed Apr 20 00:00:00 EDT 2022
Generation of autism spectrum disorder patient-derived iPSC line SDUKIi004-A.
Stem cell research
Kamand M,Ilieva M,Forsberg SL,Thomassen M,Svenningsen ÅF,Meyer M,Michel TM
14-9760-82 was used in Immunocytochemistry-immunofluorescence to try and yield new understanding about underlying neuropathological processes in autism using stem cells which may be essential for drug development.
Tue Dec 01 00:00:00 EST 2020
The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts.
Signal transduction and targeted therapy
Liu T,Zhou L,Yang K,Iwasawa K,Kadekaro AL,Takebe T,Andl T,Zhang Y
14-9760-82 was used in Immunohistochemistry to provide a new paradigm in which the β-catenin-YAP signaling axis regulates the activation and tumor-promoting function of stromal fibroblasts.
Fri Jan 29 00:00:00 EST 2021
The β-catenin/YAP signaling axis is a key regulator of melanoma-associated fibroblasts.
Signal transduction and targeted therapy
Liu T,Zhou L,Yang K,Iwasawa K,Kadekaro AL,Takebe T,Andl T,Zhang Y
14-9760-82 was used in Immunohistochemistry to provide a new paradigm in which the β-catenin-YAP signaling axis regulates the activation and tumor-promoting function of stromal fibroblasts.
Fri Jan 29 00:00:00 EST 2021
Macrophage-secreted TGF-β1 contributes to fibroblast activation and ureteral stricture after ablation injury.
American journal of physiology. Renal physiology
Ueshima E,Fujimori M,Kodama H,Felsen D,Chen J,Durack JC,Solomon SB,Coleman JA,Srimathveeravalli G
14-9760-82 was used in Immunohistochemistry to evaluate the cellular sources of TGF-β1 and scar formation at the site of injury and examine in vitro whether the effects of TGF-β1 could be attenuated by pirfenidone, using a swine model of ureteral injury with irreversible electroporation.
Mon Jul 01 00:00:00 EDT 2019
Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice.
Journal of diabetes research
Okano S,Yasui A,Kanno SI,Satoh K,Igarashi M,Nakajima O
14-9760 was used in Immunohistochemistry to study the expression of karyopherin alpha 2 in pancreatic ductal atypia and in normal pancreatic tissues.
Mon Jan 13 00:00:00 EST 2020
Material-Induced Venosome-Supported Bone Tubes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Charbonnier B,Baradaran A,Sato D,Alghamdi O,Zhang Z,Zhang YL,Gbureck U,Gilardino M,Harvey E,Makhoul N,Barralet J
14-9760 was used in Immunohistochemistry to assess the effect of a central flow-through vein on bone formation from marrow in a subcutaneous site.
Wed Sep 04 00:00:00 EDT 2019
Material-Induced Venosome-Supported Bone Tubes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Charbonnier B,Baradaran A,Sato D,Alghamdi O,Zhang Z,Zhang YL,Gbureck U,Gilardino M,Harvey E,Makhoul N,Barralet J
14-9760 was used in Immunohistochemistry to assess the effect of a central flow-through vein on bone formation from marrow in a subcutaneous site.
Wed Sep 04 00:00:00 EDT 2019
YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT.
Stem cell research & therapy
Lin F,Zeng Z,Song Y,Li L,Wu Z,Zhang X,Li Z,Ke X,Hu X
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Western Blot
Fri Aug 23 00:00:00 EDT 2019
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Tue Sep 29 00:00:00 EDT 2020
Regulatory T Cells Control the Switch From in situ to Invasive Breast Cancer.
Frontiers in immunology
Martinez LM,Robila V,Clark NM,Du W,Idowu MO,Rutkowski MR,Bos PD
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunocytochemistry
Tue Sep 29 00:00:00 EDT 2020
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ.
Nature communications
Ding L,Su Y,Fassl A,Hinohara K,Qiu X,Harper NW,Huh SJ,Bloushtain-Qimron N,Jovanović B,Ekram M,Zi X,Hines WC,Alečković M,Gil Del Alcazar C,Caulfield RJ,Bonal DM,Nguyen QD,Merino VF,Choudhury S,Ethington G,Panos L,Grant M,Herlihy W,Au A,Rosson GD,Argani P,Richardson AL,Dillon D,Allred DC,Babski K,Kim EMH,McDonnell CH,Wagner J,Rowberry R,Bobolis K,Kleer CG,Hwang ES,Blum JL,Cristea S,Sicinski P,Fan R,Long HW,Sukumar S,Park SY,Garber JE,Bissell M,Yao J,Polyak K
14-9760-82 was used in Immunohistochemistry (Paraffin) to investigate myoepithelial cells in normal breast tissues of BRCA1 and BRCA2 germline mutation carriers and in non-carrier controls, and in sporadic DCIS.
Fri Sep 13 00:00:00 EDT 2019
Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice.
PloS one
Johnson BL,d'Alincourt Salazar M,Mackenzie-Dyck S,D'Apuzzo M,Shih HP,Manuel ER,Diamond DJ
14-9760-82 was used in Immunohistochemistry to study acinar cell-derived pancreatic ductal adenocarcinoma (PDAC) initiation by developing a genetically engineered mouse model of PDAC.
Thu Mar 05 00:00:00 EST 2020
Human ISL1+ Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction.
Molecular therapy : the journal of the American Society of Gene Therapy
Foo KS,Lehtinen ML,Leung CY,Lian X,Xu J,Keung W,Geng L,Kolstad TRS,Thams S,Wong AO,Wong N,Bylund K,Zhou C,He X,Jin SB,Clarke J,Lendahl U,Li RA,Louch WE,Chien KR
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunohistochemistry
Thu Jul 05 00:00:00 EDT 2018
Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.
eLife
Lin JR,Izar B,Wang S,Yapp C,Mei S,Shah PM,Santagata S,Sorger PK
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunofluorescence
Wed Jul 11 00:00:00 EDT 2018
Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma.
Inflammation
Chauhan PS,Dash D,Singh R
14976082 was used in western blot to study the effect of intranasal curcumin on airway remodeling and fibrosis in murine model of chronic asthma
Wed Feb 01 00:00:00 EST 2017
Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system.
Nature communications
Kaur H,Carvalho J,Looso M,Singh P,Chennupati R,Preussner J,Günther S,Albarrán-Juárez J,Tischner D,Classen S,Offermanns S,Wettschureck N
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Flow Cytometry
Fri Jun 16 00:00:00 EDT 2017
Acellular Gelatinous Material of Human Umbilical Cord Enhances Wound Healing: A Candidate Remedy for Deficient Wound Healing.
Frontiers in physiology
Bakhtyar N,Jeschke MG,Mainville L,Herer E,Amini-Nik S
14-9760 was used in Immunohistochemistry on paraffin embedded tissues to investigate the effects of treatment with acellular gelatinous Wharton's jelly on wound healing in vitro and in vivo.
Thu Oct 01 00:00:00 EDT 2020
Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.
Nature communications
Chen Q,Zhang H,Liu Y,Adams S,Eilken H,Stehling M,Corada M,Dejana E,Zhou B,Adams RH
Published figure using Alpha-Smooth Muscle Actin monoclonal antibody (Product # 14-9760-82) in Immunofluorescence
Fri Aug 12 00:00:00 EDT 2016
Monoclonal antibodies against muscle actin isoforms: epitope identification and analysis of isoform expression by immunoblot and immunostaining in normal and regenerating skeletal muscle.
F1000Research
Chaponnier C,Gabbiani G
14-9760 was used in Immunofluorescence on frozen tissues to indicate that a restricted myocyte population expresses α-CAA and suggest a high capacity of self-regeneration in muscle cells.
Mon Jun 27 00:00:00 EDT 2016
