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Angiopoietin 1 Polyclonal Antibody

Angiopoietin 1 Antibody in Immunocytochemistry (ICC/IF)

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Angiopoietin 1 Antibody (23302-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 23302-1-AP (Angiopoietin 1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Angiopoietin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Angiopoietin 1 Antibody in Western Blot (WB)

Product Image Gallery

Product Details

23302-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 19 publications 19 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Angiopoietin 1 Fusion Protein Ag18829 (161-293 aa encoded by BC152411)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.31 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: IQLLENSLS TYKLEKQLLQ QTNEILKIHE KNSLLEHKIL EMEGKHKEEL DTLKEEKENL QGLVTRQTYI IQELEKQLNR ATTNNSVLQK QQLELMDTVH NLVNLCTKEG VLLKGGKREE EKPFRDCADV YQAG (161-293 aa encoded by B C152411)

Target Information

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Transplantation of Human Amniotic Mesenchymal Stem Cells Up-Regulates Angiogenic Factor Expression to Attenuate Diabetic Kidney Disease in Rats.

Diabetes, metabolic syndrome and obesity : targets and therapy

Ni Y,Chen Y,Jiang X,Pu T,Zhang L,Li S,Hu L,Bai B,Hu T,Yu L,Yang Y

Wed Feb 15 00:00:00 EST 2023

Transplantation of Human Amniotic Mesenchymal Stem Cells Up-Regulates Angiogenic Factor Expression to Attenuate Diabetic Kidney Disease in Rats.

Diabetes, metabolic syndrome and obesity : targets and therapy

Ni Y,Chen Y,Jiang X,Pu T,Zhang L,Li S,Hu L,Bai B,Hu T,Yu L,Yang Y

Wed Feb 15 00:00:00 EST 2023

Transplantation of Human Amniotic Mesenchymal Stem Cells Up-Regulates Angiogenic Factor Expression to Attenuate Diabetic Kidney Disease in Rats.

Diabetes, metabolic syndrome and obesity : targets and therapy

Ni Y,Chen Y,Jiang X,Pu T,Zhang L,Li S,Hu L,Bai B,Hu T,Yu L,Yang Y

Wed Feb 15 00:00:00 EST 2023

The Key Role of Initiation Timing on Stroke Rehabilitation by Remote Ischemic Conditioning with Exercise (RICE).

Neurological research

Wang Q,Wehbe A,Wills M,Li F,Geng X,Ding Y

Sat Apr 01 00:00:00 EDT 2023

Engineered nanovesicles from stromal vascular fraction promote angiogenesis and adipogenesis inside decellularized adipose tissue through encapsulating growth factors.

Scientific reports

Tu J,Zeng Y,An R,Sun J,Wen H

Fri Jan 13 00:00:00 EST 2023

Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

Simats A,Ramiro L,Valls R,de Ramón H,García-Rodríguez P,Orset C,Artigas L,Sardon T,Rosell A,Montaner J

Tue Mar 01 00:00:00 EST 2022

The PDE5 inhibitor, vardenafil, ameliorates progressive pathological changes in a focal segmental glomerulosclerosis mouse model.

Life sciences

Hu SW,Wang YH,Huang JS,Yang YM,Wu CC,Cheng CW

Tue Nov 15 00:00:00 EST 2022

High yield engineered nanovesicles from ADSC with enriched miR-21-5p promote angiogenesis in adipose tissue regeneration.

Biomaterials research

Sun D,Mou S,Chen L,Yang J,Wang R,Zhong A,Wang W,Tong J,Wang Z,Sun J

Sat Dec 17 00:00:00 EST 2022

Hyperoxia-induced S1P₁ signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.

Cell biochemistry and biophysics

Sudhadevi T,Jafri A,Ha AW,Basa P,Thomas JM,Fu P,Wary K,Mehta D,Natarajan V,Harijith A

Wed Sep 01 00:00:00 EDT 2021

Hyperoxia-induced S1P₁ signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.

Cell biochemistry and biophysics

Sudhadevi T,Jafri A,Ha AW,Basa P,Thomas JM,Fu P,Wary K,Mehta D,Natarajan V,Harijith A

Wed Sep 01 00:00:00 EDT 2021

Si-Wu-Tang facilitates ovarian function through improving ovarian microenvironment and angiogenesis in a mouse model of premature ovarian failure.

Journal of ethnopharmacology

Zhou F,Song Y,Liu X,Zhang C,Li F,Hu R,Huang Y,Ma W,Song K,Zhang M

Mon Nov 15 00:00:00 EST 2021

Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing.

JBMR plus

do Monte FA,Ahuja N,Awad KR,Pan Z,Young S,Kim HK,Aswath P,Brotto M,Varanasi VG

Thu Apr 01 00:00:00 EDT 2021

Macrophages enhance lipopolysaccharide induced apoptosis via Ang1 and NF-κB pathways in human umbilical vein endothelial cells.

Scientific reports

Cai GL,Yang ZX,Guo DY,Hu CB,Yan ML,Yan J

Wed Feb 03 00:00:00 EST 2021

IGFBP-4 enhances VEGF-induced angiogenesis in a mouse model of myocardial infarction.

Journal of cellular and molecular medicine

Wo D,Chen J,Li Q,Ma E,Yan H,Peng J,Zhu W,Fang Y,Ren DN

Sat Aug 01 00:00:00 EDT 2020

MicroRNA‑21 contributes to renal cell carcinoma cell invasiveness and angiogenesis via the PDCD4/c‑Jun (AP‑1) signalling pathway.

International journal of oncology

Fan B,Jin Y,Zhang H,Zhao R,Sun M,Sun M,Yuan X,Wang W,Wang X,Chen Z,Liu W,Yu N,Wang Q,Liu T,Li X

Wed Jan 01 00:00:00 EST 2020

Forkhead Box Q1 Is Critical to Angiogenesis and Macrophage Recruitment of Colorectal Cancer.

Frontiers in oncology

Tang H,Zheng J,Bai X,Yue KL,Liang JH,Li DY,Wang LP,Wang JL,Guo Q

Fri Dec 18 00:00:00 EST 2020

Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.

Molecular therapy. Nucleic acids

Wang Y,Lu J,Chen L,Bian H,Hu J,Li D,Xia C,Xu H

Fri Jun 05 00:00:00 EDT 2020

Tumor-Derived EV-Encapsulated miR-181b-5p Induces Angiogenesis to Foster Tumorigenesis and Metastasis of ESCC.

Molecular therapy. Nucleic acids

Wang Y,Lu J,Chen L,Bian H,Hu J,Li D,Xia C,Xu H

Fri Jun 05 00:00:00 EDT 2020

Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.

CNS neuroscience & therapeutics

Zhou PT,Wang LP,Qu MJ,Shen H,Zheng HR,Deng LD,Ma YY,Wang YY,Wang YT,Tang YH,Tian HL,Zhang ZJ,Yang GY

Sat Jun 01 00:00:00 EDT 2019

Sinomenine mitigates collagen-induced arthritis mice by inhibiting angiogenesis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Feng ZT,Yang T,Hou XQ,Wu HY,Feng JT,Ou BJ,Cai SJ,Li J,Mei ZG

Wed May 01 00:00:00 EDT 2019

miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.

Angiogenesis

Liang H,Ge F,Xu Y,Xiao J,Zhou Z,Liu R,Chen C

Thu Nov 01 00:00:00 EDT 2018

miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.

Angiogenesis

Liang H,Ge F,Xu Y,Xiao J,Zhou Z,Liu R,Chen C

Thu Nov 01 00:00:00 EDT 2018

miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.

Angiogenesis

Liang H,Ge F,Xu Y,Xiao J,Zhou Z,Liu R,Chen C

Thu Nov 01 00:00:00 EDT 2018

miR-153 inhibits the migration and the tube formation of endothelial cells by blocking the paracrine of angiopoietin 1 in breast cancer cells.

Angiogenesis

Liang H,Ge F,Xu Y,Xiao J,Zhou Z,Liu R,Chen C

Thu Nov 01 00:00:00 EDT 2018

Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.

Neuroscience letters

Wang Y,Zhang R,Xing X,Guo J,Xie F,Zhang G,Qin X

Mon Jan 01 00:00:00 EST 2018

Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.

Neuroscience letters

Wang Y,Zhang R,Xing X,Guo J,Xie F,Zhang G,Qin X

Mon Jan 01 00:00:00 EST 2018

MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.

Stem cell research & therapy

Qian D,Song G,Ma Z,Wang G,Jin L,Hu M,Song Z,Wang X

Thu Oct 25 00:00:00 EDT 2018

MicroRNA-9 modified bone marrow-derived mesenchymal stem cells (BMSCs) repair severe acute pancreatitis (SAP) via inducing angiogenesis in rats.

Stem cell research & therapy

Qian D,Song G,Ma Z,Wang G,Jin L,Hu M,Song Z,Wang X

Thu Oct 25 00:00:00 EDT 2018

Neuregulin-1 Promotes Myocardial Angiogenesis in the Rat Model of Diabetic Cardiomyopathy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Gui C,Zeng ZY,Chen Q,Luo YW,Li L,Chen LL

Fri Aug 17 00:00:00 EDT 2018

Neuregulin-1 Promotes Myocardial Angiogenesis in the Rat Model of Diabetic Cardiomyopathy.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Gui C,Zeng ZY,Chen Q,Luo YW,Li L,Chen LL

Fri Aug 17 00:00:00 EDT 2018

Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.

British journal of pharmacology

Zhang F,Hao M,Jin H,Yao Z,Lian N,Wu L,Shao J,Chen A,Zheng S

Wed Mar 01 00:00:00 EST 2017

Canonical hedgehog signalling regulates hepatic stellate cell-mediated angiogenesis in liver fibrosis.

British journal of pharmacology

Zhang F,Hao M,Jin H,Yao Z,Lian N,Wu L,Shao J,Chen A,Zheng S

Wed Mar 01 00:00:00 EST 2017

Bioinformatics

Protein Aliases: ANG-1; Angiopoietin-1

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Gene Aliases: 1110046O21Rik; AGP1; AGPT; Agpt1; Ang-1; ANG1; ANGPT1; KIAA0003

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UniProt ID: (Human) Q15389, (Mouse) O08538, (Rat) O35460

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Entrez Gene ID: (Human) 284, (Mouse) 11600, (Rat) 89807

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Function(s)

Ras guanyl-nucleotide exchange factor activity receptor tyrosine kinase binding receptor binding vascular endothelial growth factor receptor binding molecular_function intercellular signal molecule

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Angiopoietin 1 Polyclonal Antibody

Angiopoietin 1 Antibody (23302-1-AP) in ICC/IF

Product Details

23302-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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