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Annexin A1 Polyclonal Antibody

Annexin A1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 11

Annexin A1 Antibody (55018-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human oesophagus tissue slide using 55018-1-AP ( Annexin A1 antibody at dilution of 1:50 (under 40x lens).

Annexin A1 Antibody in Western Blot (WB)

Annexin A1 Antibody in Flow Cytometry (Flow)

Product Image Gallery

Product Details

55018-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

ANXA1 is a pleiotrophic protein produced by many cell types including peripheral blood leucocytes. The antibody is specific to ANXA1.

Target Information

Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis.

Nature communications

Fankhaenel M,Hashemi FSG,Mourao L,Lucas E,Hosawi MM,Skipp P,Morin X,Scheele CLGJ,Elias S

Wed Jan 11 00:00:00 EST 2023

YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.

Journal of experimental & clinical cancer research : CR

Li W,Ye K,Li X,Liu X,Peng M,Chen F,Xiong W,Wang Y,Zhu L

Wed Aug 17 00:00:00 EDT 2022

Platelet-derived microvesicles regulate vascular smooth muscle cell energy metabolism via PRKAA after intimal injury.

Journal of cell science

Yan J,Fan YJ,Bao H,Li YG,Zhang SM,Yao QP,Huo YL,Jiang ZL,Qi YX,Han Y

Fri Apr 01 00:00:00 EDT 2022

Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4⁺ T Cells.

Mediators of inflammation

Huang P,Zhou Y,Liu Z,Zhang P

Fri May 19 00:00:00 EDT 2017

Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4⁺ T Cells.

Mediators of inflammation

Huang P,Zhou Y,Liu Z,Zhang P

Fri May 19 00:00:00 EDT 2017

Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4⁺ T Cells.

Mediators of inflammation

Huang P,Zhou Y,Liu Z,Zhang P

Fri May 19 00:00:00 EDT 2017

Interaction between ANXA1 and GATA-3 in Immunosuppression of CD4⁺ T Cells.

Mediators of inflammation

Huang P,Zhou Y,Liu Z,Zhang P

Fri May 19 00:00:00 EDT 2017

iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus.

Journal of proteomics

Guo X,Hu H,Chen F,Li Z,Ye S,Cheng S,Zhang M,He Q

Fri Jan 01 00:00:00 EST 2016

iTRAQ-based comparative proteomic analysis of Vero cells infected with virulent and CV777 vaccine strain-like strains of porcine epidemic diarrhea virus.

Journal of proteomics

Guo X,Hu H,Chen F,Li Z,Ye S,Cheng S,Zhang M,He Q

Fri Jan 01 00:00:00 EST 2016

Co-overexpression of Hsp90-β and annexin A1 with a significantly positive correlation contributes to the diagnosis of lung cancer.

Expert review of molecular diagnostics

Biaoxue R,Shuanying Y,Wei L,Zongjuan M,Xiguang C,Qiuhong Z

Sat Nov 01 00:00:00 EDT 2014

Co-overexpression of Hsp90-β and annexin A1 with a significantly positive correlation contributes to the diagnosis of lung cancer.

Expert review of molecular diagnostics

Biaoxue R,Shuanying Y,Wei L,Zongjuan M,Xiguang C,Qiuhong Z

Sat Nov 01 00:00:00 EDT 2014

Elevated serum annexin A1 as potential diagnostic marker for lung cancer: a retrospective case-control study.

American journal of translational research

Rong B,Zhao C,Liu H,Ming Z,Cai X,Gao W,Yang S

Fri Oct 31 00:00:00 EDT 2014

Elevated serum annexin A1 as potential diagnostic marker for lung cancer: a retrospective case-control study.

American journal of translational research

Rong B,Zhao C,Liu H,Ming Z,Cai X,Gao W,Yang S

Fri Oct 31 00:00:00 EDT 2014

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients.

Journal of experimental & clinical cancer research : CR

Biaoxue R,Xiling J,Shuanying Y,Wei Z,Xiguang C,Jinsui W,Min Z

Tue Aug 28 00:00:00 EDT 2012

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients.

Journal of experimental & clinical cancer research : CR

Biaoxue R,Xiling J,Shuanying Y,Wei Z,Xiguang C,Jinsui W,Min Z

Tue Aug 28 00:00:00 EDT 2012

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients.

Journal of experimental & clinical cancer research : CR

Biaoxue R,Xiling J,Shuanying Y,Wei Z,Xiguang C,Jinsui W,Min Z

Tue Aug 28 00:00:00 EDT 2012

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients.

Journal of experimental & clinical cancer research : CR

Biaoxue R,Xiling J,Shuanying Y,Wei Z,Xiguang C,Jinsui W,Min Z

Tue Aug 28 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: ANAX1; Annexin 1 (p35) (Lipocortin 1); Annexin A1; Annexin I; annexin I (lipocortin I); Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; lipocortin 1; Lipocortin I; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1

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Gene Aliases: Anx-1; Anx-A1; ANX1; ANXA1; C430014K04Rik; Lpc-1; LPC1; p35

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UniProt ID: (Human) P04083, (Mouse) P10107, (Rat) P07150

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Entrez Gene ID: (Human) 301, (Mouse) 16952, (Rat) 25380

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Function(s)

single-stranded DNA binding single-stranded RNA binding helicase activity receptor binding structural molecule activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding phospholipase A2 inhibitor activity protein binding, bridging double-stranded DNA-dependent ATPase activity annealing helicase activity protein homodimerization activity calcium-dependent protein binding cadherin binding involved in cell-cell adhesion phospholipase inhibitor activity calcium-binding protein

Process(es)

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Annexin A1 Polyclonal Antibody

Annexin A1 Antibody (55018-1-AP) in IHC (P)

Product Details

55018-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Miscellaneous PubMed (Misc)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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