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Annexin A1 Antibody (PA5-19084) in IHC (P)
Immunohistochemistry analysis of Annexin A1 in human prostate. Samples were incubated with Annexin A1 polyclonal antibody (Product # PA5-19084) using a dilution of 4 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-19084
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (CQAILDETKGDYEK) corresponding to the C-terminus amino acids of ANXA1
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_10979557
Product Specific Information
This antibody is predicted to react with bovine and canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
Target Information
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANAX1; Annexin 1 (p35) (Lipocortin 1); Annexin A1; Annexin I; annexin I (lipocortin I); Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; lipocortin 1; Lipocortin I; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1
Gene Aliases: Anx-1; Anx-A1; ANX1; ANXA1; C430014K04Rik; Lpc-1; LPC1; p35
UniProt ID: (Human) P04083, (Pig) P19619, (Mouse) P10107, (Rat) P07150
Entrez Gene ID: (Human) 301, (Pig) 396942, (Mouse) 16952, (Rat) 25380
single-stranded DNA binding
single-stranded RNA binding
helicase activity
receptor binding
structural molecule activity
calcium ion binding
protein binding
phospholipid binding
calcium-dependent phospholipid binding
phospholipase A2 inhibitor activity
protein binding, bridging
double-stranded DNA-dependent ATPase activity
annealing helicase activity
protein homodimerization activity
calcium-dependent protein binding
cadherin binding involved in cell-cell adhesion
phospholipase inhibitor activity
calcium-binding protein
DNA strand renaturation
neutrophil homeostasis
adaptive immune response
monocyte chemotaxis
regulation of leukocyte migration
phagocytosis
inflammatory response
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
regulation of cell shape
response to X-ray
myoblast migration involved in skeletal muscle regeneration
peptide cross-linking
insulin secretion
keratinocyte differentiation
prostate gland development
endocrine pancreas development
positive regulation of vesicle fusion
positive regulation of prostaglandin biosynthetic process
actin cytoskeleton reorganization
response to estradiol
DNA duplex unwinding
regulation of interleukin-1 production
positive regulation of interleukin-2 production
positive regulation of neutrophil apoptotic process
DNA rewinding
gliogenesis
positive regulation of T cell proliferation
response to drug
negative regulation of apoptotic process
response to peptide hormone
estrous cycle
innate immune response
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of exocytosis
alpha-beta T cell differentiation
regulation of hormone secretion
arachidonic acid secretion
regulation of inflammatory response
cellular response to hydrogen peroxide
hepatocyte differentiation
prolactin secretion
response to interleukin-1
cellular response to glucocorticoid stimulus
granulocyte chemotaxis
positive regulation of wound healing
neutrophil clearance
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of phospholipase A2 activity
negative regulation of interleukin-8 secretion
negative regulation of catalytic activity
regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of protein secretion
response to hormone
response to organic cyclic compound
response to corticosteroid
response to glucocorticoid
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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