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Annexin A2 Polyclonal Antibody

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Antibody Testing Data (15)

Annexin A2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 15

Annexin A2 Antibody (11256-1-AP) in ICC/IF

Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using 11256-1-AP (Annexin A2 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

Annexin A2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Annexin A2 Antibody in Western Blot (WB)

Annexin A2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11256-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 41 publications 41 publications

Immunohistochemistry (IHC)

View 14 publications 14 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 11 publications 11 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 6 publications 6 publications

RNA Immunoprecipitation (RIP)

View 2 publications 2 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Not applicable (N/A)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Chicken, Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Annexin A2 Fusion Protein Ag1777 (1-339 aa encoded by BC016774)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSTVHEILC KLSLEGDHST PPSAYGSVKA YTNFDAERDA LNIETAIKTK GVDEVTIVNI LTNRSNAQRQ DIAFAYQRRT KKELASALKS ALSGHLETVI LGLLKTPAQY DASELKASMK GLGTDEDSLI EIICSRTNQE LQEINRVYKE MYKTDLEKDI ISDTSGDFRK LMVALAKGRR AEDGSVIDYE LIDQDARDLY DAGVKRKGTD VPKWISIMTE RSVPHLQKVF DRYKSYSPYD MLESIRKEVK GDLENAFLNL VQCIQNKPLY FADRLYDSMK GKGTRDKVLI RIMVSRSEVD MLKIRSEFKR KYGKSLYYYI QQDTKGDYQK ALLYLCGGDD (1-339 aa encoded by BC016774)

Target Information

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Wed Apr 12 00:00:00 EDT 2023

Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A2.

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Komalasari NLGY,Tomonobu N,Kinoshita R,Chen Y,Sakaguchi Y,Gohara Y,Jiang F,Yamamoto KI,Murata H,Ruma IMW,Sumardika IW,Zhou J,Yamauchi A,Kuribayashi F,Inoue Y,Toyooka S,Sakaguchi M

Tue Apr 25 00:00:00 EDT 2023

Downregulation of Calreticulin and Annexin A2 Expression in Acquired Middle Ear Cholesteatoma by 2-DE Analysis.

The Annals of otology, rhinology, and laryngology

Chang NC,Wu YJ,Wang LF,Chan LP,Chai CY,Chen Ms WT,Tsai SM,Chien CY,Ho KY

Thu Jun 01 00:00:00 EDT 2023

Downregulation of Calreticulin and Annexin A2 Expression in Acquired Middle Ear Cholesteatoma by 2-DE Analysis.

The Annals of otology, rhinology, and laryngology

Chang NC,Wu YJ,Wang LF,Chan LP,Chai CY,Chen Ms WT,Tsai SM,Chien CY,Ho KY

Thu Jun 01 00:00:00 EDT 2023

Baicalin Attenuates Continuous Activation of β-Catenin Induced by Lipopolysaccharide (LPS) and Depression Complicated by Infertility in Male Rats.

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AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.

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Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity.

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Wed Sep 14 00:00:00 EDT 2022

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

Journal of cellular and molecular medicine

Xu Y,Bao X,Chen X,Wu P,Chen S,Zhang B,Ma J,Xu G,Ma D

Tue Mar 01 00:00:00 EST 2022

HK1 from hepatic stellate cell-derived extracellular vesicles promotes progression of hepatocellular carcinoma.

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LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 EDT 2022

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 EDT 2022

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 EDT 2022

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 EDT 2022

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

Cell death & disease

Wang J,He Z,Liu X,Xu J,Jiang X,Quan G,Jiang J

Thu Aug 18 00:00:00 EDT 2022

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Cellular & molecular immunology

Chen R,Wang K,Feng Z,Zhang MY,Wu J,Geng JJ,Chen ZN

Fri Jan 01 00:00:00 EST 2021

YAP-dependent proliferation by a small molecule targeting annexin A2.

Nature chemical biology

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Thu Jul 01 00:00:00 EDT 2021

TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.

Cell death & disease

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Wed Jan 06 00:00:00 EST 2021

TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.

Cell death & disease

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Wed Jan 06 00:00:00 EST 2021

TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy.

Cell death & disease

Zhang HT,Zeng Q,Wu B,Lu J,Tong KL,Lin J,Liu QY,Xu L,Yang J,Liu X,Liu W,Zhang YF,Lian Q,Liu L,Gao X

Wed Jan 06 00:00:00 EST 2021

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Journal of cellular and molecular medicine

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Wed Dec 01 00:00:00 EST 2021

5α-Epoxyalantolactone Inhibits Metastasis of Triple-Negative Breast Cancer Cells by Covalently Binding a Conserved Cysteine of Annexin A2.

Journal of medicinal chemistry

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Thu Sep 09 00:00:00 EDT 2021

LINC01133 promotes hepatocellular carcinoma progression by sponging miR-199a-5p and activating annexin A2.

Clinical and translational medicine

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Molecular and cellular biochemistry

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Fri Oct 01 00:00:00 EDT 2021

Interaction of FLNA and ANXA2 promotes gefitinib resistance by activating the Wnt pathway in non-small-cell lung cancer.

Molecular and cellular biochemistry

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Fri Oct 01 00:00:00 EDT 2021

Interaction of FLNA and ANXA2 promotes gefitinib resistance by activating the Wnt pathway in non-small-cell lung cancer.

Molecular and cellular biochemistry

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Biochemical and biophysical research communications

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Thu Mar 12 00:00:00 EDT 2020

Transgelin-2 contributes to proliferation and progression of hepatocellular carcinoma via regulating Annexin A2.

Biochemical and biophysical research communications

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Thu Mar 12 00:00:00 EDT 2020

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Tue Feb 16 00:00:00 EST 2021

(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.

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Tue Mar 31 00:00:00 EDT 2020

(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.

Biomolecules

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Tue Mar 31 00:00:00 EDT 2020

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Annexin A2 is involved in activation of extracellular signal-regulated kinase upon endothelin-1 stimulation.

Biochemical and biophysical research communications

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Tue Mar 26 00:00:00 EDT 2019

Annexin A2 is involved in activation of extracellular signal-regulated kinase upon endothelin-1 stimulation.

Biochemical and biophysical research communications

Mazaki Y,Higashi T,Horinouchi T,Miwa S

Tue Mar 26 00:00:00 EDT 2019

Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder.

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Li X,Pei G,Zhang L,Cao Y,Wang J,Yu L,Dianjun W,Gao S,Zhang ZS,Yao Z,Wang Q

Sun Dec 01 00:00:00 EST 2019

Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder.

EBioMedicine

Li X,Pei G,Zhang L,Cao Y,Wang J,Yu L,Dianjun W,Gao S,Zhang ZS,Yao Z,Wang Q

Sun Dec 01 00:00:00 EST 2019

NUDT21 inhibits bladder cancer progression through ANXA2 and LIMK2 by alternative polyadenylation.

Theranostics

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Wed Sep 16 00:00:00 EDT 2020

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Nature immunology

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Mon Oct 01 00:00:00 EDT 2018

Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway.

Journal of cellular physiology

Zhang M,Chen D,Zhen Z,Ao J,Yuan X,Gao X

Thu Mar 01 00:00:00 EST 2018

Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway.

Journal of cellular physiology

Zhang M,Chen D,Zhen Z,Ao J,Yuan X,Gao X

Thu Mar 01 00:00:00 EST 2018

Mechanism of endogenous digitalis-like factor‑induced vascular endothelial cell damage in patients with severe preeclampsia.