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ABS 037-18-02 detects aprotinin in bovine samples.
ABS 037-18-02 has been successfully used in ELISA procedures. PBS buffers are unsuitable for these assays and 0.2M glycine sodium buffer, pH 8.8, is recommended.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Aprotinin, also called bovine pancreatic trypsin inhibitor, is a single chain globular Kunitz-type serine proteinase inhibitor found in bovine pancreas, parotid gland and lung. It forms stable, enzymatically inactive complexes with trypsin, chymotrypsin, plasmin and kallikrein. Aprotinin has been used therapeutically as an antifibrinolytic agent under the name Trasylol (Bayer) to reduce blood loss during cardiopulmonary bypass surgery but this use has been associated with an increased frequency of acute renal injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aprotinin; basic protease inhibitor; trypsin ihibitor
Gene Aliases: BPI; BPTI
Entrez Gene ID: (Bovine) 404172
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