Invitrogen

Aquaporin 5 Polyclonal Antibody

4 Published Figures

9 References

View all (16) Aquaporin 5 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (6)
Published Figures (4)

Aquaporin 5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 10

Aquaporin 5 Antibody (PA5-36529) in IHC (P)

Immunohistochemistry analysis of Aquaporin 5 in paraffin-embedded human lung carcinoma tissue. Samples were incubated with Aquaporin 5 polyclonal antibody (Product # PA5-36529) at a dilution of 1:100.

Aquaporin 5 Antibody in Western Blot (WB)

Aquaporin 5 Antibody in Immunohistochemistry (IHC)

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Product Details

PA5-36529

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 220-265 of Human AQP5.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2553573

Product Specific Information

This antibody detects endogenous protein at a molecular weight of 36 kDa.

Purity is >95% by SDS-PAGE.

Target Information

Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Fusu mixture alleviates inflammatory reactions in lipopolysaccharide-induced acute respiratory distress syndrome mice via regulation of surfactant-associated protein C, aquaporin 5, and Notch1.

Journal of thoracic disease

Zhang S,Yue Y,Liu J,Zhi L,Zhang L,Zhang K,Ding P,Gao P,Long K

Published figure using Aquaporin 5 polyclonal antibody (Product # PA5-36529) in Immunohistochemistry (Paraffin)

Fri Jun 30 00:00:00 EDT 2023

Fusu mixture alleviates inflammatory reactions in lipopolysaccharide-induced acute respiratory distress syndrome mice via regulation of surfactant-associated protein C, aquaporin 5, and Notch1.

Journal of thoracic disease

Zhang S,Yue Y,Liu J,Zhi L,Zhang L,Zhang K,Ding P,Gao P,Long K

Published figure using Aquaporin 5 polyclonal antibody (Product # PA5-36529) in Immunohistochemistry (Paraffin)

Fri Jun 30 00:00:00 EDT 2023

AQP4-independent TRPV4 modulation of plasma membrane water permeability.

Frontiers in cellular neuroscience

Barile B,Mola MG,Formaggio F,Saracino E,Cibelli A,Gargano CD,Mogni G,Frigeri A,Caprini M,Benfenati V,Nicchia GP

PA5-36529 was used in Western Blot to provide evidence that although the Pf measured upon TRPV4 activation is lower than the one obtained in AQP4-overexpressing cells (Pf of AQP4 = 0.01667 0.0007;.

Thu Sep 21 00:00:00 EDT 2023

Thyroid hormone modulates hyperoxic neonatal lung injury and mitochondrial function.

JCI insight

Vamesu BM,Nicola T,Li R,Hazra S,Matalon S,Kaminski N,Ambalavanan N,Kandasamy J

PA5-36529 was used in Immunohistochemistry (Paraffin), Western Blot to show that TH signaling and function may play a critical role in neonatal lung injury and inhaled T3 supplementation may be useful as a therapeutic strategy for BPD.

Mon Apr 24 00:00:00 EDT 2023

dDAVP Downregulates the AQP3-Mediated Glycerol Transport via V1aR in Human Colon HCT8 Cells.

Frontiers in cell and developmental biology

Centrone M,D'Agostino M,Ranieri M,Mola MG,Faviana P,Lippolis PV,Silvestris DA,Venneri M,Di Mise A,Valenti G,Tamma G

PA5-36529 was used in Western Blotting to evaluate the action of dDAVP, a stable vasopressin analog, on the AQP3 expression and function using human colon HCT8 cells as an experimental model.

Tue Jul 26 00:00:00 EDT 2022

Differential activation of Ca²⁺ influx channels modulate stem cell potency, their proliferation/viability and tissue regeneration.

NPJ Regenerative medicine

Ahamad N,Sun Y,Nascimento Da Conceicao V,Xavier Paul Ezhilan CRD,Natarajan M,Singh BB

Published figure using Aquaporin 5 polyclonal antibody (Product # PA5-36529) in Immunohistochemistry

Wed Oct 20 00:00:00 EDT 2021

Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid Development.

International journal of environmental research and public health

Kim JH,Kim J,Kim WJ,Choi YH,Yang SR,Hong SH

PA5-36529 was used in Immunohistochemistry (Paraffin) to suggest that an hPSC-based 2D and 3D alveolar induction system could be a useful in vitro platform for evaluating the adverse effects of environmental toxins and for virus research.

Fri Nov 13 00:00:00 EST 2020

Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid Development.

International journal of environmental research and public health

Kim JH,Kim J,Kim WJ,Choi YH,Yang SR,Hong SH

Fri Nov 13 00:00:00 EST 2020

Significance of transient receptor potential vanilloid 4 and aquaporin 5 co-expression in the rat uterus at term.

Heliyon

Ducza E,Csányi A,Szőke É,Pohóczky K,Hajagos-Tóth J,Kothencz A,Tiszai Z,Gáspár R

PA5-36529 was used in Immunohistochemistry to determine the possible role of AQP5 in the osmotic regulation of TRPV4, thus in pregnant uterine contraction.

Tue Oct 01 00:00:00 EDT 2019

Bioinformatics

Protein Aliases: AQP 5; AQP-5; Aquaporin-5; Aquaporin5

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Gene Aliases: AQP-5; AQP5; PPKB

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UniProt ID: (Human) P55064, (Mouse) Q9WTY4, (Rat) P47864

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Entrez Gene ID: (Human) 362, (Mouse) 11830, (Rat) 25241

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Function(s)

protein binding water channel activity glycerol channel activity transporter activity transporter

Process(es)

water transport excretion cellular water homeostasis carbon dioxide transport glycerol transport pancreatic juice secretion ion transmembrane transport odontogenesis saliva secretion camera-type eye morphogenesis transport carbohydrate transmembrane transport transmembrane transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Aquaporin 5 Polyclonal Antibody

Aquaporin 5 Antibody (PA5-36529) in IHC (P)

Product Details

PA5-36529

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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