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Product Details
CF812199
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI5G4
Immunogen
Human recombinant protein fragment corresponding to amino acids 2-418 of human ACTR3 (NP_005712) produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
See Label
Purification
Protein A/G
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Target Information
The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-like protein 3; Actin-related protein 3; actin-related protein 3 homolog (yest); ARP3 actin-related protein 3 homolog
Gene Aliases: 1200003A09Rik; ACTR3; ARP3
UniProt ID: (Human) P61158, (Rat) Q4V7C7, (Mouse) Q99JY9
Entrez Gene ID: (Human) 10096, (Rat) 81732, (Mouse) 74117
movement of cell or subcellular component
establishment or maintenance of cell polarity
asymmetric cell division
meiotic chromosome movement towards spindle pole
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
Fc-gamma receptor signaling pathway involved in phagocytosis
ephrin receptor signaling pathway
spindle localization
cilium morphogenesis
response to carbohydrate
positive regulation of lamellipodium assembly
positive regulation of actin filament polymerization
regulation of myosin II filament organization
positive regulation of neuron differentiation
response to antibiotic
positive regulation of dendrite morphogenesis
meiotic cell cycle
positive regulation of filopodium assembly
actin filament organization
cell projection organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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