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Product Details
PA5-96744
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 309-418 of human BAAT (NP_0016921)
Conjugate
Form
Liquid
Concentration
2.36 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808546
Product Specific Information
Immunogen sequence: YLFPIEEAQG QFLFIVGEGD KTINSKAHAE QAIGQLKRHG KNNWTLLSYP GAGHLIEPPY SPLCCASTTH DLRLHWGGEV IPHAAAQEHA WKEIQRFLRK HLIPDVTSQL; Positive Samples: Jurkat, BT-474, A-549, HepG2, Mouse liver, Rat liver; Cellular Location: Cytoplasm
Target Information
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BACAT; BAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid CoA:amino acid N-acyltransferase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA thioesterase; Bile acid-CoA:amino acid N-acyltransferase; bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase; bile acid-Coenzyme A: amino acid N-acyltransferase; Choloyl-CoA hydrolase; Glycine N-choloyltransferase; Kan-1; Long-chain fatty-acyl-CoA hydrolase; taurine N-acyltransferase
Gene Aliases: AI118337; AI158864; BAAT; BACAT; BAT; kan-1
UniProt ID: (Human) Q96L31, (Mouse) Q91X34, (Rat) Q63276
Entrez Gene ID: (Human) 570, (Mouse) 12012, (Rat) 29725
receptor binding
protein binding
palmitoyl-CoA hydrolase activity
N-acyltransferase activity
transferase activity, transferring acyl groups
glycine N-choloyltransferase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
transferase activity
hydrolase activity
thiolester hydrolase activity
molecular_function
esterase
hydrolase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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