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Product Details
H00000570-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1E4
Immunogen
BAAT (NP_001692, 258 a.a. approximately 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: NGTNFPFGIP QVYHGQIHQP LPHSAQLIST NALGLLELYR TFETTQVGAS QYLFPIEEAQ GQFLFIVGEG DKTINSKAHA EQAIGQLKRH GKNNWTLL
Target Information
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BACAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid CoA:amino acid N-acyltransferase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA thioesterase; Bile acid-CoA:amino acid N-acyltransferase; Choloyl-CoA hydrolase; Glycine N-choloyltransferase; Long-chain fatty-acyl-CoA hydrolase
Gene Aliases: BAAT; BACAT; BAT
UniProt ID: (Human) Q96L31
Entrez Gene ID: (Human) 570
receptor binding
protein binding
palmitoyl-CoA hydrolase activity
N-acyltransferase activity
transferase activity, transferring acyl groups
glycine N-choloyltransferase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
esterase
hydrolase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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