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Product Details
CF504360
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI3F5
Immunogen
Full length human recombinant protein of human BCAT1 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BCAT(c); branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; Protein ECA39
Gene Aliases: BCAT1; BCATC; BCT1; ECA39; MECA39; PNAS121; PP18
UniProt ID: (Human) P54687, (Mouse) P24288
Entrez Gene ID: (Human) 586, (Dog) 486633, (Mouse) 12035
branched-chain-amino-acid transaminase activity
pyridoxal phosphate binding
identical protein binding
L-leucine transaminase activity
L-valine transaminase activity
L-isoleucine transaminase activity
catalytic activity
transaminase activity
transferase activity
transaminase
transferase
metabolite interconversion enzyme
G1/S transition of mitotic cell cycle
aspartate biosynthetic process
cell proliferation
branched-chain amino acid biosynthetic process
branched-chain amino acid catabolic process
leucine biosynthetic process
valine biosynthetic process
metabolic process
cellular amino acid biosynthetic process
branched-chain amino acid metabolic process
mitotic G1 DNA damage checkpoint
cellular response to UV
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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