Product References
Downregulation of extramitochondrial BCKDH and its uncoupling from AMP deaminase in type 2 diabetic OLETF rat hearts.
Physiological reports
Ogawa T,Kouzu H,Osanami A,Tatekoshi Y,Sato T,Kuno A,Fujita Y,Ino S,Shimizu M,Toda Y,Ohwada W,Yano T,Tanno M,Miki T,Miura T
Wed Feb 01 00:00:00 EST 2023
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism.
Cell stem cell
Han L,Dong L,Leung K,Zhao Z,Li Y,Gao L,Chen Z,Xue J,Qing Y,Li W,Pokharel SP,Gao M,Chen M,Shen C,Tan B,Small A,Wang K,Zhang Z,Qin X,Yang L,Wunderlich M,Zhang B,Mulloy JC,Marcucci G,Chen CW,Wei M,Su R,Chen J,Deng X
Thu Jan 05 00:00:00 EST 2023
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16.
Nature metabolism
Ma QX,Zhu WY,Lu XC,Jiang D,Xu F,Li JT,Zhang L,Wu YL,Chen ZJ,Yin M,Huang HY,Lei QY
Sat Jan 01 00:00:00 EST 2022
3,6-dichlorobenzo[b]thiophene-2-carboxylic acid alleviates ulcerative colitis by suppressing mammalian target of rapamycin complex 1 activation and regulating intestinal microbiota.
World journal of gastroenterology
He QZ,Wei P,Zhang JZ,Liu TT,Shi KQ,Liu HH,Zhang JW,Liu SJ
Wed Dec 14 00:00:00 EST 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Ruscogenin Alleviates Myocardial Ischemia-Induced Ferroptosis through the Activation of BCAT1/BCAT2.
Antioxidants (Basel, Switzerland)
Fu F,Lai Q,Hu J,Zhang L,Zhu X,Kou J,Yu B,Li F
Fri Mar 18 00:00:00 EDT 2022
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.
Cell reports
Yang D,Liu H,Cai Y,Lu K,Zhong X,Xing S,Song W,Zhang Y,Ye L,Zhu X,Wang T,Zhang P,Li ST,Feng J,Jia W,Zhang H,Gao P
Tue Nov 22 00:00:00 EST 2022
Targeting BCAT1 Combined with α-Ketoglutarate Triggers Metabolic Synthetic Lethality in Glioblastoma.
Cancer research
Zhang B,Peng H,Zhou M,Bao L,Wang C,Cai F,Zhang H,Wang JE,Niu Y,Chen Y,Wang Y,Hatanpaa KJ,Copland JA,DeBerardinis RJ,Wang Y,Luo W
Tue Jul 05 00:00:00 EDT 2022
Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice.
Frontiers in pharmacology
Yang Y,Zhao M,He X,Wu Q,Li DL,Zang WJ
Sat Jun 05 00:00:00 EDT 2021
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.
Cellular and molecular life sciences : CMLS
Zhang B,Chen Y,Shi X,Zhou M,Bao L,Hatanpaa KJ,Patel T,DeBerardinis RJ,Wang Y,Luo W
Fri Jan 01 00:00:00 EST 2021
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1.
Basic research in cardiology
Lai Q,Yuan G,Shen L,Zhang L,Fu F,Liu Z,Zhang Y,Kou J,Liu S,Yu B,Li F
Sat Jan 23 00:00:00 EST 2021
Oxoeicosanoid receptor inhibition alleviates acute myocardial infarction through activation of BCAT1.
Basic research in cardiology
Lai Q,Yuan G,Shen L,Zhang L,Fu F,Liu Z,Zhang Y,Kou J,Liu S,Yu B,Li F
Sat Jan 23 00:00:00 EST 2021
Branched-chain amino acids govern the high learning ability phenotype in Tokai high avoider (THA) rats.
Scientific reports
Shida Y,Endo H,Owada S,Inagaki Y,Sumiyoshi H,Kamiya A,Eto T,Tatemichi M
Mon Nov 29 00:00:00 EST 2021
Transketolase Deficiency in Adipose Tissues Protects Mice From Diet-Induced Obesity by Promoting Lipolysis.
Diabetes
Tian N,Liu Q,Li Y,Tong L,Lu Y,Zhu Y,Zhang P,Chen H,Hu L,Meng J,Feng M,Li M,Zheng L,Li B,Xu T,Wu L,Tong X
Wed Jul 01 00:00:00 EDT 2020
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.
Nature cell biology
Li JT,Yin M,Wang D,Wang J,Lei MZ,Zhang Y,Liu Y,Zhang L,Zou SW,Hu LP,Zhang ZG,Wang YP,Wen WY,Lu HJ,Chen ZJ,Su D,Lei QY
Sat Feb 01 00:00:00 EST 2020
Glucose promotes cell growth by suppressing branched-chain amino acid degradation.
Nature communications
Shao D,Villet O,Zhang Z,Choi SW,Yan J,Ritterhoff J,Gu H,Djukovic D,Christodoulou D,Kolwicz SC,Raftery D,Tian R
Thu Jul 26 00:00:00 EDT 2018
Glucose promotes cell growth by suppressing branched-chain amino acid degradation.
Nature communications
Shao D,Villet O,Zhang Z,Choi SW,Yan J,Ritterhoff J,Gu H,Djukovic D,Christodoulou D,Kolwicz SC,Raftery D,Tian R
Thu Jul 26 00:00:00 EDT 2018
Glucose promotes cell growth by suppressing branched-chain amino acid degradation.
Nature communications
Shao D,Villet O,Zhang Z,Choi SW,Yan J,Ritterhoff J,Gu H,Djukovic D,Christodoulou D,Kolwicz SC,Raftery D,Tian R
Thu Jul 26 00:00:00 EDT 2018
Metabolic effects of acute thiamine depletion are reversed by rapamycin in breast and leukemia cells.
PloS one
Liu S,Miriyala S,Keaton MA,Jordan CT,Wiedl C,Clair DK,Moscow JA
Sun Sep 21 00:00:00 EDT 2014
Metabolic effects of acute thiamine depletion are reversed by rapamycin in breast and leukemia cells.
PloS one
Liu S,Miriyala S,Keaton MA,Jordan CT,Wiedl C,Clair DK,Moscow JA
Sun Sep 21 00:00:00 EDT 2014