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The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BH; Bleomycin hydrolase; BLM hydrolase
Gene Aliases: AI035728; Bh; Blmh; Bmh
UniProt ID: (Mouse) Q8R016
Entrez Gene ID: (Mouse) 104184
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