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Product Details
BMP11-FITC
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 60-100 on human BMP11/GDF11 protein.
Conjugate
Excitation/Emission Max
498/517 nm
View spectra
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP-11; Bone morphogenetic protein 11; GDF-11; Growth/differentiation factor 11
Gene Aliases: BMP-11; BMP11; GDF11
UniProt ID: (Human) O95390, (Mouse) Q9Z1W4, (Rat) Q9Z217
Entrez Gene ID: (Human) 10220, (Mouse) 14561, (Rat) 29454
skeletal system development
metanephros development
ureteric bud development
nervous system development
mesoderm development
negative regulation of cell proliferation
positive regulation of pathway-restricted SMAD protein phosphorylation
spinal cord anterior/posterior patterning
pancreas development
growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of neuron differentiation
cell development
cell maturation
camera-type eye morphogenesis
palate development
SMAD protein signal transduction
organ morphogenesis
anterior/posterior pattern specification
negative regulation of cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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