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Product Details
BS-6612R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human BMP15, amino acids 321-392.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP; BMP-15; Bone morphogenetic protein; Bone morphogenetic protein 15; GDF-9B; growth differentiation factor-9B; Growth/differentiation factor 9B
Gene Aliases: AU015375; AU018861; AU021453; Bmp-15; BMP15; C86824; C87336; GDF-9B; GDF9B; ODG2; POF4
UniProt ID: (Human) O95972, (Mouse) Q9Z0L4
Entrez Gene ID: (Human) 9210, (Rat) 59302, (Mouse) 12155
ovarian follicle development
female gamete generation
positive regulation of pathway-restricted SMAD protein phosphorylation
BMP signaling pathway
regulation of apoptotic process
regulation of MAPK cascade
cell development
granulosa cell development
SMAD protein signal transduction
positive regulation of transcription, DNA-templated
Performance Guarantee
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