Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Recommended positive controls: HeLaS3, mouse liver.
Predicted reactivity: Mouse (93%), Rat (94%), Xenopus laevis (84%), Chicken (83%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; Bisphosphate 3'-nucleotidase 1; BPntase; BPntase 1; epididymis luminal protein 20; HsPIP; Inositol-polyphosphate 1-phosphatase; PAP phosphatase; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; testicular tissue protein Li 29
Gene Aliases: BPNT1; BPntase; HEL20; PIP
UniProt ID: (Human) O95861, (Mouse) Q9Z0S1
Entrez Gene ID: (Human) 10380, (Mouse) 23827
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