Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: MAEPSSARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV TSLLGAGRQS LLRTAKGTLI; Positive Samples: HeLa, Jurkat, SGC-7901, NIH/3T3; Cellular Location: Cytoplasm, Nucleus
WDR9.3 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region 2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends.
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Protein Aliases: Bromodomain and WD repeat-containing protein 1; FLJ43918; transcriptional unit N143; WD repeat domain 9; WD repeat protein WDR9-form2; WD repeat-containing protein 9
Gene Aliases: 5330419I02Rik; BRWD1; C21orf107; D530019K20Rik; DCAF19; G1-403-16; N143; repro5; WDR9
UniProt ID: (Human) Q9NSI6, (Mouse) Q921C3
Entrez Gene ID: (Human) 54014, (Mouse) 93871
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