Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 4
BST-1 Antibody (PA5-106595) in ICC/IF
Immunocytochemistry analysis of BST-1 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with BST-1 polyclonal antibody (Product # PA5-106595) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-106595
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BST1(Accession Q10588), corresponding to amino acid residues L78-P128.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854263
Product Specific Information
Antibody detects endogenous levels of total BST1.
Target Information
Bone marrow stromal cell antigen 1 (BST1) is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B cell growth. BST1, which is also known as ADP-rybosyl cyclase 2 and DAMP-1, is an enzyme which is expressed by BST1 gene in human. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ADP-ribosyl cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Antigen BP3; Bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BP-3 alloantigen; BST-1; cADPR hydrolase 2; CD157; CD157 antigen; Cyclic ADP-ribose hydrolase 2; Leukocyte antigen 65; Ly-65; NAD(+) nucleosidase; NAD+ nucleosidase
Gene Aliases: 114/A10; A530073F09; BP-3; Bp3; BST1; Bsta1; CD157; Ly65
UniProt ID: (Human) Q10588, (Rat) Q63072, (Mouse) Q64277
Entrez Gene ID: (Human) 683, (Rat) 81506, (Mouse) 12182
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support