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Invitrogen
Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106)
FIGURE: 1 / 1
Bacillus anthracis Lethal Factor Antibody (MA1-22669) in ELISA
Calibration curve in ELISA for B. Anthracis Lethal Factor Antigen determination using (Product # MA1-22668) for coating and Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106) (Product # MA1-22669) as a HRP conjugate.
Product Details
MA1-22669
Product Specifications
Species Reactivity
Bacteria
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
BAL0106
Immunogen
Highly purified lethal factor antigen of Bacillus anthracis.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_557702
Product Specific Information
MA1-22669 detects Bacillus anthracis lethal factor in Bacteria samples.
Target Information
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of the bacterium Bacillus anthracis, the causative agent of anthrax. Anthrax toxin is composed of a cell-binding protein, known as protective antigen (PA), and two enzyme components, called edema factor (EF) and lethal factor (LF). These three protein components act together to impart their physiological effects. Assembled complexes containing the toxin components are endocytosed. In the endosome, the enzymatic components of the toxin translocate into the cytoplasm of a target cell. Once in the cytosol, the enzymatic components of the toxin disrupts various immune cell functions, namely cellular signaling and cell migration. The toxin may even induce cell lysis, as is observed for macrophage cells. Anthrax toxin allows the bacteria to evade the immune system, proliferate, and ultimately kill the host animal. Research on anthrax toxin also provides insight into the generation of macromolecular assemblies, and on protein translocation, pore formation, endocytosis, and other biochemical processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anthrax LF; B. anthracis LF
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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