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Product Details
A16707
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
D24A9
Immunogen
synthetic peptide corresponding to residues surrounding Pro102 of human Bad.
Conjugate
Form
Liquid
Storage conditions
-20°C
Shipping conditions
Ambient
Target Information
The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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