Product References
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Biological trace element research
Zhang W,Sun J,Liu F,Li S,Wang X,Su L,Liu G
Thu Feb 01 00:00:00 EST 2024
ASK1 inhibitor NQDI‑1 decreases oxidative stress and neuroapoptosis via the ASK1/p38 and JNK signaling pathway in early brain injury after subarachnoid hemorrhage in rats.
Molecular medicine reports
Duan J,Yuan W,Jiang J,Wang J,Yan X,Liu F,Liu A
Wed Feb 01 00:00:00 EST 2023
YTHDF1 Attenuates TBI-Induced Brain-Gut Axis Dysfunction in Mice.
International journal of molecular sciences
Huang P,Liu M,Zhang J,Zhong X,Zhong C
Mon Feb 20 00:00:00 EST 2023
Toll-like receptors (TLR2 and TLR4) antagonist mitigates the onset of cerebral small vessel disease through PI3K/Akt/GSK3β pathway in stroke-prone renovascular hypertensive rats.
Biotechnology & genetic engineering reviews
Wang N,Guo W,Liu T,Chen X,Lin M
Mon Mar 06 00:00:00 EST 2023
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Bioengineering & translational medicine
Zhu Z,Li X,Wang X,Zuo X,Ma Y,Gao X,Liang Z,Zhang Z,Song Z,Ding T,Ju C,Li P,Li K,Zhang J,Quan H,Wang Z,Hu X
Mon May 01 00:00:00 EDT 2023
N-Acetylserotonin Protects Rat Nucleus Pulposus Cells Against Oxidative Stress Injury by Activating the PI3K/AKT Signaling Pathway.
World neurosurgery
Yidian W,Jihe K,Xudong G,Daxue Z,Mingqiang L,Xuewen K
Tue Aug 01 00:00:00 EDT 2023
Stevioside protects primary articular chondrocytes against IL-1β-induced inflammation and catabolism by targeting integrin.
International immunopharmacology
Wan J,Zhu Z,He Z,Wu H,Chen A,Zhu W,Cheng P
Thu Jun 01 00:00:00 EDT 2023
Effect of doramectin on programmed cell death pathway in glioma cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Du S,Liang H,Zhou L,Chen C,Sun R,Zhang J,Meng X,Gao A
Sun Oct 01 00:00:00 EDT 2023
Oral exposure to polystyrene nanoplastics reduced male fertility and even caused male infertility by inducing testicular and sperm toxicities in mice.
Journal of hazardous materials
Xu W,Yuan Y,Tian Y,Cheng C,Chen Y,Zeng L,Yuan Y,Li D,Zheng L,Luo T
Sat Jul 15 00:00:00 EDT 2023
GDNF-Loaded Polydopamine Nanoparticles-Based Anisotropic Scaffolds Promote Spinal Cord Repair by Modulating Inhibitory Microenvironment.
Advanced healthcare materials
Ma J,Li J,Wang X,Li M,Teng W,Tao Z,Xie J,Ma Y,Shi Q,Li B
Wed Mar 01 00:00:00 EST 2023
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Molecular medicine (Cambridge, Mass.)
Chen Y,Liu X,Li L,He X,Zheng F,Zhang Y,Gao H,Jin Z,Wu D,Wang Q,Tao H,Zhao Y,Liu W,Zou L
Mon Feb 06 00:00:00 EST 2023
Riboflavin protects against heart failure via SCAD-dependent DJ-1-Keap1-Nrf2 signalling pathway.
British journal of pharmacology
Xu Q,Cao Y,Zhong X,Qin X,Feng J,Peng H,Su Y,Ma Z,Zhou S
Fri Dec 01 00:00:00 EST 2023
Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.
Veterinary research
Feng L,Luo G,Li Y,Zhang C,Liu Y,Liu Y,Chen H,He D,Zhu Y,Gan L
Tue Mar 14 00:00:00 EDT 2023
Solanine Represses Gastric Cancer Growth by Mediating Autophagy Through AAMDC/MYC/ATF4/Sesn2 Signaling Pathway.
Drug design, development and therapy
Tang X,Guo Y,Zhang S,Wang X,Teng Y,Jin Q,Jin Q,Shen W,Wang R
Thu Feb 16 00:00:00 EST 2023
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Toxicology and applied pharmacology
Yang J,Li G,Huang Y,Liu Y
Mon May 01 00:00:00 EDT 2023
Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lan XB,Ni YS,Liu N,Wei W,Liu Y,Yang JM,Ma L,Bai R,Zhang J,Yu JQ
Wed Mar 01 00:00:00 EST 2023
Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells.
Tissue engineering and regenerative medicine
Zhang Y,Wang P,Jin MX,Zhou YQ,Ye L,Zhu XJ,Li HF,Zhou M,Li Y,Li S,Liang KY,Wang Y,Gao Y,Pan MX,Zhou SQ,Peng Q
Thu Jun 01 00:00:00 EDT 2023
Gamabufotalin Induces Apoptosis and Cytoprotective Autophagy through the mTOR Signaling Pathway in Hepatocellular Carcinoma.
Journal of natural products
Liu L,Shi D,Xia ZY,Wang BW,Wang XL,Wang XT,Wang GL,Li MJ,Zheng QS,Li D,Li BH
Fri Apr 28 00:00:00 EDT 2023
Benefits of high-intensity interval training compared to continuous training to reduce apoptotic markers in female rats with cisplatin nephrotoxicity - possible modulatory role of IL-11.
Apoptosis : an international journal on programmed cell death
Oliveira CA,Mercês ÉAB,Portela FS,De Benedictis JM,De Benedictis LM,da Silva AVB,Campanati JAG,de Melo FF,Oliveira MV,de Magalhães ACM,Soares TJ,Amaral LSB
Sat Apr 01 00:00:00 EDT 2023
Berberine promotes the viability of random skin flaps via the PI3K/Akt/eNOS signaling pathway.
Phytotherapy research : PTR
Chen J,Jiang Z,Liu X,Wang K,Fan W,Chen T,Li Z,Lin D
Wed Feb 01 00:00:00 EST 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
The alkaloids of Corydalis hendersonii Hemsl. contribute to the cardioprotective effect against ischemic injury in mice by attenuating cardiomyocyte apoptosis via p38 MAPK signaling pathway.
Chinese medicine
Ge F,Gao X,Zhou X,Li J,Ma X,Huang M,Wuken S,Tu P,An C,Chai X
Fri Mar 17 00:00:00 EDT 2023
Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis.
Naunyn-Schmiedeberg's archives of pharmacology
Wei Y,Sun L,Liu C,Li L
Thu Jun 01 00:00:00 EDT 2023
GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway.
Cellular signalling
Chen Z,Song Y,Li P,Gao W
Sat Jul 01 00:00:00 EDT 2023
Pharmacological Activation of Rev-erbα Attenuates Doxorubicin-Induced Cardiotoxicity by PGC-1α Signaling Pathway.
Cardiovascular therapeutics
Zou R,Wang S,Cai H,Wang Y,Wang C
Tue Mar 07 00:00:00 EST 2023
Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration.
International journal of biological sciences
Xu WN,Liu C,Zheng HL,Xu HX,Yang RZ,Jiang SD,Zhu LX
Thu Feb 09 00:00:00 EST 2023
Semaglutide inhibits ischemia/reperfusion-induced cardiomyocyte apoptosis through activating PKG/PKCε/ERK1/2 pathway.
Biochemical and biophysical research communications
Zhu Q,Luo Y,Wen Y,Wang D,Li J,Fan Z
Sun Mar 05 00:00:00 EST 2023
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.
Molecular medicine reports
Luo Y,Chen P,Yang L,Duan X
Sun Jan 01 00:00:00 EST 2023
Combination of pioglitazone, a PPARγ agonist, and synthetic surfactant B-YL prevents hyperoxia-induced lung injury in adult mice lung explants.
Pulmonary pharmacology & therapeutics
Kurihara C,Sakurai R,Chuang TD,Waring AJ,Walther FJ,Rehan VK
Thu Jun 01 00:00:00 EDT 2023
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Nephrology (Carlton, Vic.)
Liu Z,Xiang H,Deng Q,Fu W,Li Y,Yu Z,Qiu Y,Mei Z,Xu L
Thu Jun 01 00:00:00 EDT 2023
O-linked N-acetylglucosamine affects mitochondrial homeostasis by regulating Parkin-dependent mitophagy in hyperoxia-injured alveolar type II cells injury.
Respiratory research
Xuefei Y,Dongyan L,Tianming L,Hejuan Z,Jianhua F
Mon Jan 16 00:00:00 EST 2023
Protective effect of pinocembrin from Penthorum chinense Pursh on hepatic ischemia reperfusion injury via regulating HMGB1/TLR4 signal pathway.
Phytotherapy research : PTR
Ma T,Zhang H,Li T,Bai J,Wu Z,Cai T,Chen Y,Xia X,Du Y,Fu W
Sun Jan 01 00:00:00 EST 2023
TGF-β3 Protects Neurons Against Intermittent Hypoxia-Induced Oxidative Stress and Apoptosis Through Activation of the Nrf-2/KEAP1/HO-1 Pathway via Binding to TGF-βRI.
Neurochemical research
Huang Y,Liu Z,Wang X,Li Y,Liu L,Li B
Fri Sep 01 00:00:00 EDT 2023
Mass spectrometry-based metabolomics reveal Dendrobium huoshanense polysaccharide effects and potential mechanism of N-methyl-N'-nitro-N-nitrosoguanidine -induced damage in GES-1 cells.
Journal of ethnopharmacology
Xie H,Hu M,Yu J,Yang X,Li J,Yu N,Han L,Peng D
Wed Jun 28 00:00:00 EDT 2023
TWIST1 rescue calcium overload and apoptosis induced by inflammatory microenvironment in S. aureus-induced osteomyelitis.
International immunopharmacology
Wang Y,Dai G,Lin Z,Cheng C,Zhou X,Song M,Chen P,Ma S,Hu Y,Liu G,Yu B
Thu Jun 01 00:00:00 EDT 2023
Suppression of the gut microbiota-bile acid-FGF19 axis in patients with atrial fibrillation.
Cell proliferation
Zuo K,Fang C,Gao Y,Fu Y,Wang H,Li J,Zhong J,Yang X,Xu L
Wed Nov 01 00:00:00 EDT 2023
Screening and identification of miR-181a-5p in oral squamous cell carcinoma and functional verification in vivo and in vitro.
BMC cancer
Xu G,Yang Y,Yang J,Xiao L,Wang X,Qin L,Gao J,Xuan R,Wu X,Chen Z,Sun R,Song G
Fri Feb 17 00:00:00 EST 2023
Ginsenoside Rk1 attenuates radiation-induced intestinal injury through the PI3K/AKT/mTOR pathway.
Biochemical and biophysical research communications
Wang Y,Su P,Zhuo Z,Jin Y,Zeng R,Wu H,Huang H,Chen H,Li Z,Sha W
Sun Feb 05 00:00:00 EST 2023
Antitumor mechanism of kangliu pill on gliomas in mice through PI3K-Akt signaling pathway.
Journal of ethnopharmacology
Chen F,Cui JJ,Jiang DC,Wang HZ,Zhuang W,Feng YN,Lin XL,Xi SY
Wed May 10 00:00:00 EDT 2023
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Transplantation and cellular therapy
Wang X,Zhou Y,Sun Q,Zhang Q,Zhou H,Zhang J,Du Y,Wang Y,Yuan K,Xu L,Zhang M,Yan D,Zeng L,Xu K,Sang W
Tue Aug 01 00:00:00 EDT 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 EDT 2023
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Environmental toxicology
Wang Y,Guo Y,Liu H,Du X,Shi L,Wang W,Zhang S
Thu Jun 01 00:00:00 EDT 2023
Exploring novel biomarkers in dilated cardiomyopathy‑induced heart failure by integrated analysis and in vitro experiments.
Experimental and therapeutic medicine
Zhou L,Peng F,Li J,Gong H
Sat Jul 01 00:00:00 EDT 2023
Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway.
Autoimmunity
Yang J,Kou X
Fri Dec 01 00:00:00 EST 2023
Polysaccharide from Flammulina velutipes residues protects mice from Pb poisoning by activating Akt/GSK3β/Nrf-2/HO-1 signaling pathway and modulating gut microbiota.
International journal of biological macromolecules
Liu Y,Li H,Ren P,Che Y,Zhou J,Wang W,Yang Y,Guan L
Wed Mar 01 00:00:00 EST 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 EDT 2023
Gastroprotective effects of ginsenoside Rh4 against ethanol-induced gastric mucosal injury by inhibiting the MAPK/NF-κB signaling pathway.
Food & function
Wu Y,Duan Z,Qu L,Zhang Y,Zhu C,Fan D
Tue Jun 06 00:00:00 EDT 2023
m6A contributes to a pro-survival state in GC-2 cells by facilitating DNA damage repair: Novel perspectives on the mechanism underlying DEHP genotoxicity in male germ cells.
The Science of the total environment
Fu H,Zhu X,Di Q,Sun J,Jiang Q,Xu Q
Fri Feb 10 00:00:00 EST 2023
Piceatannol and 3'-Hydroxypterostilbene Alleviate Inflammatory Bowel Disease by Maintaining Intestinal Epithelial Integrity and Regulating Gut Microbiota in Mice.
Journal of agricultural and food chemistry
Lin WS,Chueh TL,Nagabhushanam K,Ho CT,Pan MH
Wed Feb 01 00:00:00 EST 2023
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Redox biology
Wang Z,Tan C,Duan C,Wu J,Zhou D,Hou L,Qian W,Han C,Hou X
Sat Apr 01 00:00:00 EDT 2023
Kaempferol attenuates doxorubicin-induced renal tubular injury by inhibiting ROS/ASK1-mediated activation of the MAPK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu Q,Chen J,Zheng X,Song J,Yin L,Guo H,Chen Q,Liu Y,Ma Q,Zhang H,Yang Q
Sun Jan 01 00:00:00 EST 2023
Employing single valency polyphenol to prepare metal-phenolic network antitumor reagents through FeOOH assistance.
Journal of controlled release : official journal of the Controlled Release Society
Zhang M,Wang L,Jin H,Zhao N,Liu Y,Lan S,Liu S,Zhang H
Thu Jun 01 00:00:00 EDT 2023
Glutathione Might Attenuate Arsenic-Induced Liver Injury by Modulating the Foxa2-XIAP Axis to Reduce Oxidative Stress and Mitochondrial Apoptosis.
Biological trace element research
Zhang H,Jin B,Liu L,Li H,Zheng X,Li M,He R,Wang K
Wed Nov 01 00:00:00 EDT 2023
Ganoderma lucidum polysaccharide inhibits HSC activation and liver fibrosis via targeting inflammation, apoptosis, cell cycle, and ECM-receptor interaction mediated by TGF-β/Smad signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen C,Chen J,Wang Y,Fang L,Guo C,Sang T,Peng H,Zhao Q,Chen S,Lin X,Wang X
Wed Feb 01 00:00:00 EST 2023
SIRT6 attenuates LPS-induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling.
Immunity, inflammation and disease
Yang J,Chen X
Wed Mar 01 00:00:00 EST 2023
Ginsenoside Rg1 promotes astrocyte-to-neuron transdifferentiation in rat and its possible mechanism.
CNS neuroscience & therapeutics
Shen K,Wu D,Sun B,Zhu Y,Wang H,Zou W,Ma Y,Lu Z
Sun Jan 01 00:00:00 EST 2023
Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.
Journal of ethnopharmacology
Liu J,Yang Y,He Y,Feng C,Ou H,Yang J,Chen Y,You F,Shao B,Bao J,Guan X,Chen F,Zhao P
Sat Mar 25 00:00:00 EDT 2023
The therapeutic mechanism of Yuye decoction on type 2 diabetes mellitus based on network pharmacology and experimental verification.
Journal of ethnopharmacology
Guo F,Yao L,Zhang W,Chen P,Hao R,Huang X,Jiang J,Wu S
Tue May 23 00:00:00 EDT 2023
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Translational oncology
Ye Z,Xia Y,Li L,Li B,Chen W,Han S,Zhou X,Chen L,Yu W,Ruan Y,Cheng F
Sun Jan 01 00:00:00 EST 2023
Genetic modification of miR-34a enhances efficacy of transplanted human dental pulp stem cells after ischemic stroke.
Neural regeneration research
Wang J,He P,Tian Q,Luo Y,He Y,Liu C,Gong P,Guo Y,Ye Q,Li M
Fri Sep 01 00:00:00 EDT 2023
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
International immunopharmacology
Wang J,Ren B,Yang Y,Li Y
Mon May 01 00:00:00 EDT 2023
Spermatogenesis associated serine rich 2 like plays a prognostic factor and therapeutic target in acute myeloid leukemia by regulating the JAK2/STAT3/STAT5 axis.
Journal of translational medicine
Li F,Ye W,Yao Y,Wei W,Lin X,Zhuang H,Li C,Li X,Ling Q,Hu C,Huang X,Qian Y,Mao S,Huang J,Lu Y,Jin J
Sat Feb 11 00:00:00 EST 2023
Sarsasapogenin, a principal active component absorbed into blood of total saponins of Anemarrhena, attenuates proliferation and invasion in rheumatoid arthritis fibroblast-like synoviocytes through downregulating PKM2 inhibited pathological glycolysis.
Phytotherapy research : PTR
Dai Y,Liu P,Wen W,Li P,Yang C,Wang P,Xu S
Mon May 01 00:00:00 EDT 2023
DHCR24 reverses Alzheimer's disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xFAD mice.
Acta neuropathologica communications
Zhang WB,Huang Y,Guo XR,Zhang MQ,Yuan XS,Zu HB
Wed Jun 21 00:00:00 EDT 2023
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
iScience
Li J,Hui Y,Xu Z,Tan J,Yin K,Kuang L,Tang Y,Wei J,Zhong Q,Zheng T
Fri Mar 17 00:00:00 EDT 2023
HSPA1A ameliorated spinal cord injury in rats by inhibiting apoptosis to exert neuroprotective effects.
Experimental neurology
He X,Guo X,Deng B,Kang J,Liu W,Zhang G,Wang Y,Yang Y,Kang X
Wed Mar 01 00:00:00 EST 2023
MiR-155 promotes inflammation and apoptosis via targeting SIRT1 in hypoxic-ischemic brain damage.
Experimental neurology
Ke F,Wang H,Geng J,Jing X,Fang F,Fang C,Zhang BH
Sat Apr 01 00:00:00 EDT 2023
Nobiletin inhibits de novo FA synthesis to alleviate gastric cancer progression by regulating endoplasmic reticulum stress.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Chen M,Zhang R,Chen Y,Chen X,Li Y,Shen J,Yuan M,Chen Y,Wu J,Sun Q
Tue Jul 25 00:00:00 EDT 2023
Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling.
Frontiers in pharmacology
Wu L,Lin Y,Gao S,Wang Y,Pan H,Wang Z,Pozzolini M,Yang F,Zhang H,Yang Y,Xiao L,Xu Y
Sat Jul 01 00:00:00 EDT 2023
Probiotic powder ameliorates colorectal cancer by regulating Bifidobacterium animalis, Clostridium cocleatum, and immune cell composition.
PloS one
Yang X,Cao Q,Ma B,Xia Y,Liu M,Tian J,Chen J,Su C,Duan X
Wed Mar 15 00:00:00 EDT 2023
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota.
European journal of pharmacology
Wei Y,Qi M,Liu C,Li L
Wed Apr 05 00:00:00 EDT 2023
Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds.
Scientific reports
Sun R,Liu C,Liu J,Yin S,Song R,Ma J,Cao G,Lu Y,Zhang G,Wu Z,Chen A,Wang Y
Wed Jan 04 00:00:00 EST 2023
The protective mechanism of a novel polysaccharide from Lactobacillus-fermented Nostoc commune Vauch. on attenuating cadmium-induced kidney injury in mice.
International journal of biological macromolecules
Li H,Liu Y,Zhou J,Liu S,Liu Y,Yang Y,Wang W,Che Y,Inam M,Guan L
Tue Jan 31 00:00:00 EST 2023
Wei-Tong-Xin ameliorated cisplatin-induced mitophagy and apoptosis in gastric antral mucosa by activating the Nrf2/HO-1 pathway.
Journal of ethnopharmacology
Zhang X,Wang S,Jin Y,Wang J,Wang R,Yang X,Zhang S,Yan T,Jia Y
Tue May 23 00:00:00 EDT 2023
Jiawei Yanghe Decoction suppresses breast cancer by regulating immune responses via JAK2/STAT3 signaling pathway.
Journal of ethnopharmacology
You Y,Chen X,Chen X,Li H,Zhou R,Zhou J,Chen M,Peng B,Ji S,Kwan HY,Zou L,Yu J,Liu Y,Wu Y,Zhao X
Wed Nov 15 00:00:00 EST 2023
Stomatin-like protein 2 deficiency exacerbates adverse cardiac remodeling.
Cell death discovery
Hu Y,Jiang H,Xu Y,Chen G,Fan R,Zhou Y,Liu Y,Yao Y,Liu R,Chen W,Zhang K,Chen X,Wang R,Qiu Z
Tue Feb 14 00:00:00 EST 2023
Naringin against doxorubicin-induced hepatotoxicity in mice through reducing oxidative stress, inflammation, and apoptosis via the up-regulation of SIRT1.
Environmental toxicology
Xi Y,Chi Z,Tao X,Zhai X,Zhao Z,Ren J,Yang S,Dong D
Mon May 01 00:00:00 EDT 2023
SIRT3/GLUT4 signaling activation by metformin protect against cisplatin-induced ototoxicity in vitro.
Archives of toxicology
Du P,Liu T,Luo P,Li H,Tang W,Zong S,Xiao H
Sat Apr 01 00:00:00 EDT 2023
High expression of centromere protein N as novel biomarkers for gastric adenocarcinoma.
Cancer reports (Hoboken, N.J.)
Wang X,Zhang K,Fu C,Wu F,Zhang J,Han B,Pan H,Luan L
Sat Apr 01 00:00:00 EDT 2023
Nuciferine improves random skin flap survival via TFEB-mediated activation of autophagy-lysosomal pathway.
International immunopharmacology
Xue K,Zhang G,Zhou Y,Wang K,Yao Z,Chen J,Zhang Y,Li Z,Li Z,Zheng Z,Feng Y,Mao C,Lin C,Xia W
Thu Jun 01 00:00:00 EDT 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Empagliflozin-Pretreated Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Attenuated Heart Injury.
Oxidative medicine and cellular longevity
Chi B,Zou A,Mao L,Cai D,Xiao T,Wang Y,Wang Q,Ji Y,Sun L
Wed Mar 01 00:00:00 EST 2023
Agrimoniin is a dual inhibitor of AKT and ERK pathways that inhibit pancreatic cancer cell proliferation.
Phytotherapy research : PTR
Zhang X,Chen J,Xi B,Liu Y,Wang S,Gu L,Zhao H,Tao L,Hua Y,Wang Y,Chen M
Fri Sep 01 00:00:00 EDT 2023
Vitamin D-VDR (vitamin D receptor) alleviates glucose metabolism reprogramming in lipopolysaccharide-induced acute kidney injury.
Frontiers in physiology
Dai Q,Zhang H,Tang S,Wu X,Wang J,Yi B,Liu J,Li Z,Liao Q,Li A,Liu Y,Zhang W
Tue Mar 14 00:00:00 EDT 2023
4-vinylcyclohexene diepoxide induces apoptosis by excessive reactive oxygen species and DNA damage in human ovarian granulosa cells.
Toxicology in vitro : an international journal published in association with BIBRA
Song W,Qiu YT,Li XZ,Sun QY,Chen LN
Fri Sep 01 00:00:00 EDT 2023
Particle Debris Generated from Passenger Tires Induces Morphological and Gene Expression Alterations in the Macrophages Cell Line RAW 264.7.
Nanomaterials (Basel, Switzerland)
Poma A,Aloisi M,Bonfigli A,Colafarina S,Zarivi O,Aimola P,Vecchiotti G,Arrizza L,Di Cola A,Cesare P
Fri Feb 17 00:00:00 EST 2023
Inhibition of STAT3 signaling as critical molecular event in HUC-MSCs suppressed Glioblastoma Cells.
Journal of Cancer
Wang M,Zhang Y,Liu M,Jia Y,He J,Xu X,Shi H,Zhang Y,Zhang J,Liu Y
Sat Apr 15 00:00:00 EDT 2023
Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma.
Phytotherapy research : PTR
Zhu XF,Sun ZL,Ma J,Hu B,Yu MC,Liu XJ,Yang P,Xu Y,Ju D,Mu Q
Wed Feb 01 00:00:00 EST 2023
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
International journal of impotence research
Yao L,Cong R,Zhou X,Zhou X,Ji C,Wei X,Meng X,Song N
Wed Mar 15 00:00:00 EDT 2023
The mechanism of rh-endostatin-induced cardiotoxicity and its protection by dihydromyricetin[in vivo/in vitro, C57BL/6 mice, AC16 and hiPSC-CMs].
Toxicology letters
Guan X,Li W,Wang Y,Zhao Q,Yu X,Jiang J,Bian W,Xu C,Sun Y,Zhang C
Wed Mar 15 00:00:00 EDT 2023
A Novel Myricetin Derivative with Anti-cancer Properties Induces Cell Cycle Arrest and Apoptosis in A549 Cells.
Biological & pharmaceutical bulletin
Zhou H,Xu L,Shi Y,Gu S,Wu N,Liu F,Huang Y,Qian Z,Xue W,Wang X,Chen F
Thu Jan 05 00:00:00 EST 2023
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Neurochemical research
Chen B,Wu J,Hu S,Liu Q,Yang H,You Y
Mon May 01 00:00:00 EDT 2023
Cytotoxic Steroidal Saponins Containing a Rare Fructosyl from the Rhizomes of Paris polyphylla var. latifolia.
International journal of molecular sciences
Li TY,Du Y,Wang MC,Liu K,Liu Y,Cao Y,Wang YY,Chen WW,Qian XY,Qiu PC,Tang HF,Lu YY
Wed Apr 12 00:00:00 EDT 2023
MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro.
International journal of molecular sciences
Wang J,Du H,Ma L,Feng M,Li L,Zhao X,Dai Y
Wed Jan 04 00:00:00 EST 2023
AKR1B1 Represses Glioma Cell Proliferation through p38 MAPK-Mediated Bcl-2/BAX/Caspase-3 Apoptotic Signaling Pathways.
Current issues in molecular biology
Huang YK,Chang KC,Li CY,Lieu AS,Lin CL
Thu Apr 13 00:00:00 EDT 2023
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Frontiers in pharmacology
Ma P,Huang N,Tang J,Zhou Z,Xu J,Chen Y,Zhang M,Huang Q,Cheng Y
Sat Mar 04 00:00:00 EST 2023
Shenlian extract decreases mitochondrial autophagy to regulate mitochondrial function in microvascular to alleviate coronary artery no-reflow.
Phytotherapy research : PTR
Li JJ,Wang YJ,Wang CM,Li YJ,Yang Q,Cai WY,Chen Y,Zhu XX
Mon May 01 00:00:00 EDT 2023
Network pharmacology, molecular docking, and experimental verification reveal the mechanism of San-Huang decoction in treating acute kidney injury.
Frontiers in pharmacology
Liu J,Li Z,Lao Y,Jin X,Wang Y,Jiang B,He R,Yang S
Fri Feb 24 00:00:00 EST 2023
Corilagin alleviates intestinal ischemia/reperfusion injury by relieving oxidative stress and apoptosis via AMPK/Sirt1-autophagy pathway.
Experimental biology and medicine (Maywood, N.J.)
Li B,Li W,Zheng M,Wang Y,Diao Y,Mou X,Liu J
Wed Feb 01 00:00:00 EST 2023
Resveratrol alleviates high glucose-induced oxidative stress and apoptosis in rat cardiac microvascular endothelial cell through AMPK/Sirt1 activation.
Biochemistry and biophysics reports
Li J,Feng Z,Lu B,Fang X,Huang D,Wang B
Sat Jul 01 00:00:00 EDT 2023
Effects of heat shock protein 90 on complement activation in myocardial ischemia/reperfusion injury after pioglitazone preconditioning.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Wang D,He S,Zhong G,Meng J,Bi Q,Tu R
Fri Dec 01 00:00:00 EST 2023
Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
Journal of medicinal chemistry
Zhang M,Li L,Li S,Liu Z,Zhang N,Sun B,Wang Z,Jia D,Liu M,Wang Q
Thu Mar 09 00:00:00 EST 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
ACS chemical neuroscience
Zhang Z,Guo L,Yang F,Peng S,Wang D,Lai X,Su B,Xie H
Wed May 17 00:00:00 EDT 2023
Guf1 overexpression improves pancreatic β cell functions in type 2 diabetes mellitus rats with Roux-en-Y gastric bypass (RYGB) surgery.
Journal of physiology and biochemistry
Li P,Dai S,Gao X,Li W
Tue Aug 01 00:00:00 EDT 2023
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Inflammation
Li K,Feng Z,Wang L,Ma X,Wang L,Liu K,Geng X,Peng C
Thu Jun 01 00:00:00 EDT 2023
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Tissue & cell
Cui Z,Qin R,Feng J,Liu Y,Zhou X,Qin X,Li Y,Zhang Z,He X
Tue Aug 01 00:00:00 EDT 2023
Role of selenoprotein M knockdown in the melatonin antagonism of nickel-induced apoptosis and endoplasmic reticulum stress in mouse heart.
Journal of Zhejiang University. Science. B
Zhang X,Gai X,Xu L,Ma W,Liu Q,Shi B,Fang C,Cai J,Zhang Z
Mon May 15 00:00:00 EDT 2023
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Journal of ethnopharmacology
Qi J,Luo Q,Zhang Q,Wu M,Zhang L,Qin L,Xue Q,Nie X
Mon Jun 12 00:00:00 EDT 2023
TFP5 attenuates cyclin-dependent kinase 5-mediated islet β-cell damage in diabetes.
Chemical biology & drug design
Liu S,Li B,Ma D,Tao Y,Song J,Bao L,Zhang G,Luo H,Cao S,E J,Zheng Y
Sat Jul 01 00:00:00 EDT 2023
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression.
Translational research : the journal of laboratory and clinical medicine
An X,Wu W,Yang L,Dong J,Liu B,Guo J,Chen J,Guo B,Cao W,Jiang Q
Fri Sep 01 00:00:00 EDT 2023
MiR-125b-5p/STAT3 Axis Regulates Drug Resistance in Osteosarcoma Cells by Acting on ABC Transporters.
Stem cells international
Yang Y,Chen Y,Liu J,Zhang B,Yang L,Xue J,Zhang Z,Qin L,Bian R
Thu May 11 00:00:00 EDT 2023
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
European journal of pharmacology
Yang Y,Jin Y,Yin L,Liu P,Zhu L,Gao H
Sun Mar 05 00:00:00 EST 2023
Hydrogen sulfide regulates SERCA2a SUMOylation by S-Sulfhydration of SENP1 to ameliorate cardiac systole-diastole function in diabetic cardiomyopathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Peng S,Wang M,Zhang S,Liu N,Li Q,Kang J,Chen L,Li M,Pang K,Huang J,Lu F,Zhao D,Zhang W
Sat Apr 01 00:00:00 EDT 2023
The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice.
eLife
Xu K,Su X,Fang K,Lv Y,Huang T,Li M,Wang Z,Yin Y,Muhammad T,Liu S,Chen X,Jiang J,Li J,Chan WY,Ma J,Lu G,Chen ZJ,Liu H
Tue Mar 21 00:00:00 EDT 2023
Integrating metabolomics and network pharmacology to investigate Panax japonicus prevents kidney injury in HFD/STZ-induced diabetic mice.
Journal of ethnopharmacology
Wang T,Huang X,Zhai K,Yu J,Li J,Duan H,Liu J,Lu Z,Guo J,Li F
Wed Mar 01 00:00:00 EST 2023
Allicin ameliorates imiquimod-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A.
British journal of pharmacology
Zhang L,Ma X,Shi R,Zhang L,Zhao R,Duan R,Qin Y,Gao S,Li X,Duan J,Li J
Wed Mar 01 00:00:00 EST 2023
Effects of chronic realgar exposure on liver lipidome in mice and identification sensitive lipid biomarker model for realgar-induced liver damage.
Toxicology letters
Huo T,Zhang W,Yang J,Li J,Zhang Y,Guo H,Wu X,Li A,Feng C,Jiang H
Sun Jan 01 00:00:00 EST 2023
The effect of regulating MCU expression on experimental ischemic brain injury.
Experimental neurology
Qin J,Liu L,Liu L,Zhou Z,Zhou Y,Zhang K,Wang B,Lu H,Ran J,Ma T,Zhang Y,Li Z,Liu X
Sat Apr 01 00:00:00 EDT 2023
The MAD2B-APC/C-MDM2 axis mediates acute kidney injury by modulating p53.
The FEBS journal
Hao Z,Yuan Q,Tang H,Lei C,Chen Y,Su H,Zhang C
Tue Aug 01 00:00:00 EDT 2023
Acrylamide interferes with autophagy and induces apoptosis in Neuro-2a cells by interfering with TFEB-regulated lysosomal function.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Pang P,Zhang X,Yuan J,Yan H,Yan D
Sat Jul 01 00:00:00 EDT 2023
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer.
Acta pharmacologica Sinica
Wang YF,Zhao LN,Geng Y,Yuan HF,Hou CY,Zhang HH,Yang G,Zhang XD
Sun Jan 01 00:00:00 EST 2023
Magnolol improves Alzheimer's disease-like pathologies and cognitive decline by promoting autophagy through activation of the AMPK/mTOR/ULK1 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang X,Jia J
Mon May 01 00:00:00 EDT 2023
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Journal of ethnopharmacology
Wu S,Tian C,Tu Z,Guo J,Xu F,Qin W,Chang H,Wang Z,Hu T,Sun X,Ning H,Li Y,Gou W,Hou W
Sat Jul 15 00:00:00 EDT 2023
Pre-ischaemic Treatment with Enriched Environment Alleviates Acute Neuronal Injury by Inhibiting Endoplasmic Reticulum Stress-dependent Autophagy and Apoptosis.
Neuroscience
Han Y,Shen XY,Gao ZK,Ping Han P,Bi X
Wed Mar 01 00:00:00 EST 2023
Desferoxamine protects against hemophilic arthropathy through the upregulation of HIF-1α-BNIP3 mediated mitophagy.
Life sciences
Lin J,Guo Z,Zheng Z,Hou L,Xu J,Liu Q,Du T,Guo F,Jing X
Sun Jan 01 00:00:00 EST 2023
TRIM38 protects H9c2 cells from hypoxia/reoxygenation injury via the TRAF6/TAK1/NF-κB signalling pathway.
PeerJ
Lu Z,Deng M,Ma G,Chen L
Tue Jan 17 00:00:00 EST 2023
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cui C,Zang N,Song J,Guo X,He Q,Hu H,Yang M,Wang Y,Yang J,Zou Y,Gao J,Wang L,Wang C,Liu F,He F,Hou X,Chen L
Sat Oct 01 00:00:00 EDT 2022
Drp1-Mediated Mitochondrial Metabolic Dysfunction Inhibits the Tumor Growth of Pituitary Adenomas.
Oxidative medicine and cellular longevity
Fan K,Ding X,Zang Z,Zhang Y,Tang X,Pei X,Chen Q,Yin H,Zheng X,Chen Y,Li S,Yang H
Tue Apr 05 00:00:00 EDT 2022
PRUNE2 inhibits progression of colorectal cancer in vitro and in vivo.
Experimental and therapeutic medicine
Li T,Huang S,Yan W,Zhang Y,Guo Q
Tue Feb 01 00:00:00 EST 2022
Exogenous hydrogen sulfide inhibits the senescence of cardiomyocytes through modulating mitophagy in rats.
Cellular signalling
Hao J,Xi Y,Jiao L,Wen X,Wu R,Chang G,Sun F,Wei C,Li H
Thu Dec 01 00:00:00 EST 2022
Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.
Journal of ethnopharmacology
Li JJ,Wang CM,Wang YJ,Yang Q,Cai WY,Li YJ,Song M,Zang YL,Cui XH,Li Q,Chen Y,Weng XG,Zhu XX
Sun Apr 24 00:00:00 EDT 2022
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Inflammation
Chen S,Huang Y,Su H,Zhu W,Wei Y,Long Y,Shi Y,Wei J
Mon Aug 01 00:00:00 EDT 2022
SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis.
International immunopharmacology
Long Q,Li L,Yang H,Lu Y,Yang H,Zhu Y,Tang Y,Liu C,Yuan J
Thu Sep 01 00:00:00 EDT 2022
USF1-CHCHD4 axis promotes lung adenocarcinoma progression partially via activating the MYC pathway.
Discover. Oncology
Zhou Y,Zhao Y,Ma W,Zhang L,Jiang Y,Dong W
Thu Dec 08 00:00:00 EST 2022
Integrated strategy of network pharmacology, molecular docking, HPLC-DAD and mice model for exploring active ingredients and pharmacological mechanisms of Penthorum chinense Pursh against alcoholic liver injury.
Journal of ethnopharmacology
Jiang Y,Zhong M,Zhan H,Tao X,Zhang Y,Mao J,Geng Z,Gao B
Tue Nov 15 00:00:00 EST 2022
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hao M,Ding C,Peng X,Chen H,Dong L,Zhang Y,Chen X,Liu W,Luo Y
Sat Oct 01 00:00:00 EDT 2022
Simvastatin Improves Outcomes of Endotoxin-induced Coagulopathy by Regulating Intestinal Microenvironment.
Current medical science
Xu M,Luo LL,Du MY,Tang L,Zhou J,Hu Y,Mei H
Tue Feb 01 00:00:00 EST 2022
GYY4137 ameliorates sepsis-induced cardiomyopathy via NLRP3 pathway.
Biochimica et biophysica acta. Molecular basis of disease
Zhou T,Qian H,Zheng N,Lu Q,Han Y
Thu Dec 01 00:00:00 EST 2022
Platelet membrane-camouflaged nanoparticles carry microRNA inhibitor against myocardial ischaemia‒reperfusion injury.
Journal of nanobiotechnology
Wang T,Zhou T,Xu M,Wang S,Wu A,Zhang M,Zhou YL,Shi J
Tue Oct 04 00:00:00 EDT 2022
Neuroprotective effects of alisol A 24-acetate on cerebral ischaemia-reperfusion injury are mediated by regulating the PI3K/AKT pathway.
Journal of neuroinflammation
Lu T,Li H,Zhou Y,Wei W,Ding L,Zhan Z,Liu W,Tao J,Xue X
Mon Feb 07 00:00:00 EST 2022
Platelet-rich plasma pretreatment protects anterior cruciate ligament fibroblasts correlated with PI3K-Akt-mTOR pathway under hypoxia condition.
Journal of orthopaedic translation
Cao Y,Li Y,Fu SC,Shen J,Zhang H,Jiang C,Shu-Hang Yung P
Sun May 01 00:00:00 EDT 2022
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
Toxicology
Tang L,Yu J,Zhuge S,Chen H,Zhang L,Jiang G
Mon Aug 01 00:00:00 EDT 2022
Aerobic Exercise Alleviates Abnormal Autophagy in Brain Cells of APP/PS1 Mice by Upregulating AdipoR1 Levels.
International journal of molecular sciences
Jian Y,Yuan S,Yang J,Lei Y,Li X,Liu W
Wed Aug 31 00:00:00 EDT 2022
Lycium barbarum polysaccharide attenuates Pseudomonas-aeruginosa pyocyanin-induced cellular injury in mice airway epithelial cells.
Food & nutrition research
Lin X,Song F,Wu Y,Xue D,Wang Y
Thu Mar 10 00:00:00 EST 2022
Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.
Frontiers in molecular biosciences
Zou P,Zhang X,Zhang R,Chai X,Zhao Y,Li E,Zhang Q,Yan R,Yang J,Liao B
Sat Apr 09 00:00:00 EDT 2022
Focused Ultrasound Promotes the Delivery of Gastrodin and Enhances the Protective Effect on Dopaminergic Neurons in a Mouse Model of Parkinson's Disease.
Frontiers in cellular neuroscience
Wang Y,Luo K,Li J,Liao Y,Liao C,Chen WS,Chen M,Ao L
Sat Jul 16 00:00:00 EDT 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 EDT 2022
Recurrent Hypoglycemia Impaired Vascular Function in Advanced T2DM Rats by Inducing Pyroptosis.
Oxidative medicine and cellular longevity
Luo M,Hu Y,Lv D,Xie L,Yang S,Zuo D,Xue Y,He A
Wed Aug 03 00:00:00 EDT 2022
A pH-Dependent rhodamine fluorophore with antiproliferative activity of bladder cancer in Vitro/Vivo and apoptosis mechanism.
European journal of medicinal chemistry
Lu D,Yang T,Tang N,Li C,Song Y,Wang L,Wong WY,Yin SF,Xing Y,Kambe N,Qiu R
Sun Jun 05 00:00:00 EDT 2022
Gaseous signal molecule SO2 regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhao J,Wu Q,Yang T,Nie L,Liu S,Zhou J,Chen J,Jiang Z,Xiao T,Yang J,Chu C
Tue Nov 01 00:00:00 EDT 2022
Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis.
Mediators of inflammation
Yang W,Wang Y,Zhang P,Wang T,Li C,Tong X,Zeng X,Yin Y,Tao K,Li R
Thu Mar 31 00:00:00 EDT 2022
Identification of potential key circular RNAs related to cognitive impairment after chronic constriction injury of the sciatic nerve.
Frontiers in neuroscience
Liu C,Gao R,Tang Y,Chen H,Zhang X,Sun Y,Zhao Q,Lv P,Wang H,Ye-Lehmann S,Liu J,Chen C
Wed Sep 07 00:00:00 EDT 2022
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
Discover. Oncology
Luan H,Yan L,Zhao Y,Ding X,Cao L
Mon Oct 03 00:00:00 EDT 2022
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent.
European journal of medicinal chemistry
Liang JJ,Yu WL,Yang L,Qin KM,Yin YP,Li D,Ni YH,Yan JJ,Zhong YX,Deng ZX,Hong K
Sun Jun 05 00:00:00 EDT 2022
HRK inhibits colorectal cancer cells proliferation by suppressing the PI3K/AKT/mTOR pathway.
Frontiers in oncology
Wang H,Chen Y,Yuan Q,Chen L,Dai P,Li X
Tue Jan 03 00:00:00 EST 2023
Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival.
Communications biology
Chen Z,Wu H,Yang J,Li B,Ding J,Cheng S,Bsoul N,Zhang C,Li J,Liu H,Lin D,Gao W
Wed Jun 22 00:00:00 EDT 2022
The preventive and therapeutic effect of repetitive transcranial magnetic stimulation on radiation-induced brain injury in mice.
International journal of radiation biology
Liu LY,Qin TZ,Guo L,Rong-Rong H,Jing YT,Lai PP,Xue YZ,Ding GR
Wed Jul 27 00:00:00 EDT 2022
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Aging
Tai H,Cui XZ,He J,Lan ZM,Li SM,Li LB,Yao SC,Jiang XL,Meng XS,Kuang JS
Thu Oct 20 00:00:00 EDT 2022
Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats.
Aging
Tai H,Cui XZ,He J,Lan ZM,Li SM,Li LB,Yao SC,Jiang XL,Meng XS,Kuang JS
Thu Oct 20 00:00:00 EDT 2022
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
Oxidative medicine and cellular longevity
Jia C,Li X,Pan J,Ma H,Wu D,Lu H,Wang W,Zhang X,Yi X
Fri Sep 09 00:00:00 EDT 2022
LncRNA-Airn alleviates acute liver injury by inhibiting hepatocyte apoptosis via the NF-κB signaling pathway.
Acta biochimica et biophysica Sinica
Shao S,Zhang Y,Zhou F,Meng X,Yu Z,Li G,Zheng L,Zhang K,Li Y,Guo B,Liu Q,Zhang M,Du X,Hong W,Han T
Fri Nov 25 00:00:00 EST 2022
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Journal of translational medicine
Zhou GP,Li SP,Jiang YZ,Sun J,Tan YL,Zeng ZG,Wei L,Qu W,Sun LY,Zhu ZJ
Thu Oct 20 00:00:00 EDT 2022
Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion.
Frontiers in endocrinology
Jiang S,Xu CM,Yao S,Zhang R,Li XZ,Zhang RZ,Xie TY,Xing YQ,Zhang Q,Zhou XJ,Liao L,Dong JJ
Tue Aug 30 00:00:00 EDT 2022
DEAD-box helicase 56 functions as an oncogene promote cell proliferation and invasion in gastric cancer via the FOXO1/p21 Cip1/c-Myc signaling pathway.
Bioengineered
Wang J,Wang Y,Wang J,Zhang S,Yu Z,Zheng K,Fu Z,Wang C,Huang W,Chen J
Sun May 01 00:00:00 EDT 2022
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang B,Wan S,Liu H,Qiu Q,Chen H,Chen Z,Wang L,Liu X
Wed Oct 26 00:00:00 EDT 2022
Dexmedetomidine post-conditioning protects blood-brain barrier integrity by modulating microglia/macrophage polarization via inhibiting NF-κB signaling pathway in intracerebral hemorrhage.
Frontiers in molecular neuroscience
Guo H,Zhang W,Wang Z,Li Z,Zhou J,Yang Z
Fri Sep 30 00:00:00 EDT 2022
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Andrologia
Fu W,Chen S,Zhang Z,Chen Y,You X,Li Q
Sat Oct 01 00:00:00 EDT 2022
ASIC1a induces mitochondrial apoptotic responses in acute lung injury.
European journal of pharmacology
Li Y,Zhang A,Li K,Zhao D,Li F,Liao S,Zhang Y,Huang Y
Sat Nov 05 00:00:00 EDT 2022
ASIC1a induces mitochondrial apoptotic responses in acute lung injury.
European journal of pharmacology
Li Y,Zhang A,Li K,Zhao D,Li F,Liao S,Zhang Y,Huang Y
Sat Nov 05 00:00:00 EDT 2022
Targeting NOX4 disrupts the resistance of papillary thyroid carcinoma to chemotherapeutic drugs and lenvatinib.
Cell death discovery
Tang P,Sheng J,Peng X,Zhang R,Xu T,Hu J,Kang Y,Wu B,Dang H
Fri Apr 08 00:00:00 EDT 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Abscopal effects of thoracic X-ray radiation on spermatogenesis in mice.
Frontiers in physiology
Lai PP,Jing YT,Guo L,Qin TZ,Xue YZ,Zhang ZW,Wang X,Miao X,Zhang W,Ding GR
Tue Sep 13 00:00:00 EDT 2022
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.
Physiological research
Liu X,Zhang K,Wang L,Geng B,Liu Z,Yi Q,Xia Y
Fri Dec 16 00:00:00 EST 2022
MiR-383-5p promotes apoptosis of ovarian granulosa cells by targeting CIRP through the PI3K/AKT signaling pathway.
Archives of gynecology and obstetrics
Li Y,Wu X,Miao S,Cao Q
Mon Aug 01 00:00:00 EDT 2022
Venetoclax enhances DNA damage induced by XPO1 inhibitors: A novel mechanism underlying the synergistic antileukaemic effect in acute myeloid leukaemia.
Journal of cellular and molecular medicine
Yu H,Wu S,Liu S,Li X,Gai Y,Lin H,Wang Y,Edwards H,Ge Y,Wang G
Sun May 01 00:00:00 EDT 2022
Downregulation of lncRNA APCDD1L-AS1 due to DNA hypermethylation and loss of VHL protein expression promotes the progression of clear cell renal cell carcinoma.
International journal of biological sciences
Yang W,Zhou J,Zhang Z,Zhang K,Xu Y,Li L,Cai L,Gong Y,Gong K
Thu Apr 14 00:00:00 EDT 2022
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Respiratory research
Dai Z,Liu X,Zeng H,Chen Y
Sat Dec 17 00:00:00 EST 2022
CDGSH iron sulfur domain 2 mitigates apoptosis, oxidative stress and inflammatory response caused by oxygen-glucose deprivation/reoxygenation in HT22 hippocampal neurons by Akt-Nrf2-activated pathway.
Metabolic brain disease
Ren X,Yu J,Guo L,Zhang Z
Sat Oct 01 00:00:00 EDT 2022
Label-free Raman spectroscopy characterizes signatures of inflammation and fibrosis in the silicosis.
Biochemical and biophysical research communications
Wang W,Mu M,Zou Y,Li B,Cao H,Hu D,Tao X
Sat May 28 00:00:00 EDT 2022
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Food & function
Lu H,Yin H,Qu L,Ma X,Fu R,Fan D
Mon Apr 04 00:00:00 EDT 2022
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Frontiers in medicine
Pei Z,Wu M,Yu H,Long G,Gui Z,Li X,Chen H,Jia Z,Xia W
Tue May 03 00:00:00 EDT 2022
L-Theanine-Treated Adipose-Derived Mesenchymal Stem Cells Alleviate the Cytotoxicity Induced by N-Nitrosodiethylamine in Liver.
Tissue engineering and regenerative medicine
Lai YJ,Sung YT,Lai YA,Chen LN,Chen TS,Chien CT
Thu Dec 01 00:00:00 EST 2022
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Journal of clinical laboratory analysis
Yao J,Wu J,Jia S,Shao J,Zhang X,Xu Z,Zhang H,Li H,Yao X
Thu Dec 01 00:00:00 EST 2022
Neddylation Inhibition Causes Impaired Mouse Embryo Quality and Blastocyst Hatching Failure Through Elevated Oxidative Stress and Reduced IL-1β.
Frontiers in immunology
Yang G,Chen J,He Y,Luo H,Yuan H,Chen L,Huang L,Mao F,Hu S,Qian Y,Miao C,Feng R
Fri Jul 22 00:00:00 EDT 2022
Ginsenoside CK induces apoptosis in triple-negative breast cancer cells by targeting glutamine metabolism.
Biochemical pharmacology
Zhang B,Fu R,Duan Z,Shen S,Zhu C,Fan D
Mon Aug 01 00:00:00 EDT 2022
Mitogen-activating protein kinase kinase kinase kinase-3, inhibited by Astragaloside IV through H3 lysine 4 monomethylation, promotes the progression of diabetic nephropathy by inducing apoptosis.
Bioengineered
Fan Y,Fan H,Li P,Liu Q,Huang L,Zhou Y
Sun May 01 00:00:00 EDT 2022
BaZiBuShen alleviates cognitive deficits and regulates Sirt6/NRF2/HO-1 and Sirt6/P53-PGC-1α-TERT signaling pathways in aging mice.
Journal of ethnopharmacology
Li L,Zhang H,Chen B,Xia B,Zhu R,Liu Y,Dai X,Ye Z,Zhao D,Mo F,Gao S,Orekhov AN,Prentki M,Wang L,Guo S,Zhang D
Mon Jan 10 00:00:00 EST 2022
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Molecular neurobiology
Yang X,Wang M,Zhou Q,Bai Y,Liu J,Yang J,Li L,Li G,Luo L
Sun May 01 00:00:00 EDT 2022
Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway.
Molecular neurobiology
Yang X,Wang M,Zhou Q,Bai Y,Liu J,Yang J,Li L,Li G,Luo L
Sun May 01 00:00:00 EDT 2022
DHA-Enriched Phospholipids and EPA-Enriched Phospholipids Alleviate Lipopolysaccharide-Induced Intestinal Barrier Injury in Mice via a Sirtuin 1-Dependent Mechanism.
Journal of agricultural and food chemistry
Du L,Hao YM,Yang YH,Zheng Y,Wu ZJ,Zhou MQ,Wang BZ,Wang YM,Wu H,Su GH
Wed Mar 09 00:00:00 EST 2022
Downregulation of HULC Induces Ferroptosis in Hepatocellular Carcinoma via Targeting of the miR-3200-5p/ATF4 Axis.
Oxidative medicine and cellular longevity
Guan L,Wang F,Wang M,Han S,Cui Z,Xi S,Xu H,Li S
Fri May 27 00:00:00 EDT 2022
Circadian Rhythm Disorders Aggravate Periodontitis by Modulating BMAL1.
International journal of molecular sciences
Liu X,Cao N,Liu X,Deng Y,Xin Y,Fu R,Xin X,Hou Y,Yu W
Mon Dec 26 00:00:00 EST 2022
Morroniside Protects Human Granulosa Cells against H2O2-Induced Oxidative Damage by Regulating the Nrf2 and MAPK Signaling Pathways.
Evidence-based complementary and alternative medicine : eCAM
Ma Y,Hao G,Lin X,Zhao Z,Yang A,Cao Y,Zhang S,Fan L,Geng J,Zhang Y,Chen J,Song C,He M,Du H
Tue Sep 20 00:00:00 EDT 2022
Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis.
PeerJ
Wang H,Jiang C,Yang Y,Li J,Wang Y,Wang C,Gao Y
Mon Jan 16 00:00:00 EST 2023
Quercetin Attenuates Quinocetone-Induced Cell Apoptosis In Vitro by Activating the P38/Nrf2/HO-1 Pathway and Inhibiting the ROS/Mitochondrial Apoptotic Pathway.
Antioxidants (Basel, Switzerland)
Dai C,Zhang Q,Shen L,Sharma G,Jiang H,Wang Z,Shen J
Sat Jul 30 00:00:00 EDT 2022
Induction of Collagen I by CXCL10 in Ovarian Theca-Stroma Cells via the JNK Pathway.
Frontiers in endocrinology
Wang C,Sun Y
Tue Apr 19 00:00:00 EDT 2022
Myocardium-Targeted Micelle Nanomedicine That Salvages the Heart from Ischemia/Reperfusion Injury.
ACS applied materials & interfaces
Yang L,Peng J,Shi A,Wang X,Li J,Su Y,Yin K,Zhao L,Zhao Y
Wed Aug 31 00:00:00 EDT 2022
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Frontiers in pharmacology
Li Y,Deng Y,Zhang X,Fu H,Han X,Guo W,Zhao W,Zhao X,Yu C,Li H,Lei K,Wang T
Sat Jul 16 00:00:00 EDT 2022
Protective effect of nicorandil against myocardial ischemia/reperfusion injury mediated via IL33/ST2 signaling pathway.
Molecular and cellular biochemistry
Zheng Y,Li X,Zhang F,Zhao B,Du W,Sun D,Li G
Fri Jul 01 00:00:00 EDT 2022
CORM-3 Attenuates Oxidative Stress-Induced Bone Loss via the Nrf2/HO-1 Pathway.
Oxidative medicine and cellular longevity
Jin C,Lin BH,Zheng G,Tan K,Liu GY,Yao Z,Xie J,Chen WK,Chen L,Xu TH,Huang CB,Wu ZY,Yang L
Tue Aug 30 00:00:00 EDT 2022
Modified Linggui Zhugan Decoction protects against ventricular remodeling through ameliorating mitochondrial damage in post-myocardial infarction rats.
Frontiers in cardiovascular medicine
Xiang M,Zhao X,Lu Y,Zhang Y,Ding F,Lv L,Wang Y,Shen Z,Li L,Cui X
Thu Feb 02 00:00:00 EST 2023
Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy.
Molecular therapy oncolytics
Tang X,Peng H,Xu P,Zhang L,Fu R,Tu H,Guo X,Huang K,Lu J,Chen H,Dong Z,Dai L,Luo J,Chen Q
Thu Mar 17 00:00:00 EDT 2022
Roles of C/EBP-homologous protein and histone H3 lysine 4 methylation in arsenic-induced mitochondrial apoptosis in hepatocytes.
Toxicology and industrial health
Liang C,Xie RJ,Wang JL,Zhang YW,Zhang JY,Yang Q,Han B
Tue Nov 01 00:00:00 EDT 2022
Knockdown of Annexin A2 Enhances Radiosensitivity by Increasing G2/M-Phase Arrest, Apoptosis and Activating the p38 MAPK-HSP27 Pathway in Nasopharyngeal Carcinoma.
Frontiers in oncology
He H,Lin K,Zou C,Pan J,Fu W,Zhou Y,Lin H,Chen C,Su Y
Tue Apr 05 00:00:00 EDT 2022
Di-2-ethylhexyl phthalate-induced miR-155-5p promoted lipid metabolism via inhibiting cAMP/PKA signaling pathway in human trophoblastic HTR-8/Svneo cells.
Reproductive toxicology (Elmsford, N.Y.)
Gu X,Liu H,Luo W,Wang X,Wang H,Li L
Thu Dec 01 00:00:00 EST 2022
Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in Patients.
Oxidative medicine and cellular longevity
Lu Z,Shen J,Chen X,Ruan Z,Cai W,Cai S,Li M,Yang Y,Mo J,Mo G,Lu Y,Tang J,Zhang L
Tue Apr 12 00:00:00 EDT 2022
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
Reproductive biology and endocrinology : RB&E
Tang X,Dong H,Fang Z,Li J,Yang Q,Yao T,Pan Z
Tue May 24 00:00:00 EDT 2022
β-Hydroxybutyrate against Cisplatin-Induced acute kidney injury via inhibiting NLRP3 inflammasome and oxidative stress.
International immunopharmacology
Luo S,Yang M,Han Y,Zhao H,Jiang N,Li L,Chen W,Li C,Yang J,Liu Y,Liu C,Zhao C,Sun L
Sat Oct 01 00:00:00 EDT 2022
Kaempferol From Penthorum chinense Pursh Attenuates Hepatic Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Inflammation Through Activation of the Nrf2/HO-1 Signaling Pathway.
Frontiers in pharmacology
Chen Y,Li T,Tan P,Shi H,Cheng Y,Cai T,Bai J,Du Y,Fu W
Sat Jul 16 00:00:00 EDT 2022
Dl-3-n-Butylphthalide Improves Neuroinflammation in Mice with Repeated Cerebral Ischemia-Reperfusion Injury through the Nrf2-Mediated Antioxidant Response and TLR4/MyD88/NF-κB Signaling Pathway.
Oxidative medicine and cellular longevity
Gao Y,Hu M,Niu X,Li M,Xu L,Xiao Y,Zhang J,Wang H,Li L,Chu B,Lv P
Tue Dec 13 00:00:00 EST 2022
Ophiopogonin D'-induced mitophagy and mitochondrial damage are associated with dysregulation of the PINK1/Parkin signaling pathway in AC16 cells.
Toxicology
Lei S,Feng Y,Huang P,Chen B,Bao K,Wu Q,Zhang H,Huang X
Fri Jul 01 00:00:00 EDT 2022
A novel synthetic chalcone derivative, 2,4,6-trimethoxy-4'-nitrochalcone (Ch-19), exerted anti-tumor effects through stimulating ROS accumulation and inducing apoptosis in esophageal cancer cells.
Cell stress & chaperones
Yang Y,Wu H,Zou X,Chen Y,He R,Jin Y,Zhou B,Ge C,Yang Y
Tue Nov 01 00:00:00 EDT 2022
Harpagoside Protects Against Doxorubicin-Induced Cardiotoxicity via P53-Parkin-Mediated Mitophagy.
Frontiers in cell and developmental biology
Li W,Wang X,Liu T,Zhang Q,Cao J,Jiang Y,Sun Q,Li C,Wang W,Wang Y
Tue Mar 01 00:00:00 EST 2022
The Photoperiod Regulates Granulosa Cell Apoptosis through the FSH-Nodal/ALK7 Signaling Pathway in Phodopus sungorus.
Animals : an open access journal from MDPI
Qi Y,Xue HL,Zheng YJ,Yin YF,Xu WL,Xu JH,Wu M,Chen L,Xu LX
Fri Dec 16 00:00:00 EST 2022
Proanthocyanidins inhibit the apoptosis and aging of nucleus pulposus cells through the PI3K/Akt pathway delaying intervertebral disc degeneration.
Connective tissue research
Chen HW,Liu MQ,Zhang GZ,Zhang CY,Wang ZH,Lin AX,Kang JH,Liu WZ,Guo XD,Wang YD,Kang XW
Tue Nov 01 00:00:00 EDT 2022
Expression and potential role of FOSB in glioma.
Frontiers in molecular neuroscience
Qi M,Sun LA,Zheng LR,Zhang J,Han YL,Wu F,Zhao J,Niu WH,Fei MX,Jiang XC,Zhou ML
Wed Nov 02 00:00:00 EDT 2022
Overexpression of sFlt-1 represses ox-LDL-induced injury of HUVECs by activating autophagy via PI3K/AKT/mTOR pathway.
Microvascular research
Zhou YH,Tang YZ,Guo LY,Zheng LL,Zhang D,Yang CY,Wang W
Sat Jan 01 00:00:00 EST 2022
A derivant of ginsenoside CK and its inhibitory effect on hepatocellular carcinoma.
Life sciences
Zhang J,Tong Y,Lu X,Dong F,Ma X,Yin S,He Y,Liu Y,Liu Q,Fan D
Thu Sep 01 00:00:00 EDT 2022
NEDD4 attenuates phosgene-induced acute lung injury through the inhibition of Notch1 activation.
Journal of cellular and molecular medicine
Shao Y,Jiang Z,He D,Shen J
Sun May 01 00:00:00 EDT 2022
Yap is essential for uterine decidualization through Rrm2/GSH/ROS pathway in response to Bmp2.
International journal of biological sciences
Yu HF,Yang ZQ,Xu MY,Huang JC,Yue ZP,Guo B
Thu Apr 14 00:00:00 EDT 2022
Investigation of the inhibition effect of 1,2,3,4,6-pentagalloyl-β-D-glucose on gastric cancer cells based on a network pharmacology approach and experimental validation.
Frontiers in oncology
Bi JH,Jiang YH,Ye SJ,Wu MR,Yi Y,Wang HX,Wang LM
Tue Aug 23 00:00:00 EDT 2022
HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.
ACS chemical neuroscience
Sun W,Zhang N,Liu B,Yang J,Loers G,Siebert HC,Wen M,Zheng X,Wang Z,Han J,Zhang R
Wed Sep 07 00:00:00 EDT 2022
Pretreatment of nucleus pulposus mesenchymal stem cells with appropriate concentration of H2O2 enhances their ability to treat intervertebral disc degeneration.
Stem cell research & therapy
Zhang YY,Hu ZL,Qi YH,Li HY,Chang X,Gao XX,Liu CH,Li YY,Lou JH,Zhai Y,Li CQ
Tue Jul 26 00:00:00 EDT 2022
Tanshinone IIA Accomplished Protection against Radiation-Induced Cardiomyocyte Injury by Regulating the p38/p53 Pathway.
Mediators of inflammation
Wang G,Ma L,Wang B,Gao F,Li J,Cai H,Wang J,Zhang T,Guo H,Xie P,Li Y
Wed Sep 07 00:00:00 EDT 2022
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
International journal of biological sciences
Gou W,Luo N,Yu B,Wu H,Wu S,Tian C,Guo J,Ning H,Bi C,Wei H,Hou W,Li Y
Thu Apr 14 00:00:00 EDT 2022
Salidroside inhibited cerebral ischemia/reperfusion-induced oxidative stress and apoptosis via Nrf2/Trx1 signaling pathway.
Metabolic brain disease
Li F,Mao Q,Wang J,Zhang X,Lv X,Wu B,Yan T,Jia Y
Thu Dec 01 00:00:00 EST 2022
Covalent Organic Framework (COF): A Drug and Carrier to Attenuate Retinal Ganglion Cells Death in an Acute Glaucoma Mouse Model.
Polymers
Yao K,Liang X,Zhang G,Rong Y,Zhang Q,Liao Q,Zhang H,Xi K,Wang J
Wed Aug 10 00:00:00 EDT 2022
Protective Effects of Liquiritigenin against Cisplatin-Induced Nephrotoxicity via NRF2/SIRT3-Mediated Improvement of Mitochondrial Function.
Molecules (Basel, Switzerland)
Zhou M,Dai Y,Ma Y,Yan Y,Hua M,Gao Q,Geng X,Zhou Q
Tue Jun 14 00:00:00 EDT 2022
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
International journal of biological sciences
Wu X,Wei S,Chen M,Li J,Wei Y,Zhang J,Dong W
Mon Aug 22 00:00:00 EDT 2022
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
Pharmaceutical biology
He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X
Thu Dec 01 00:00:00 EST 2022
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
Pharmaceutical biology
He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X
Thu Dec 01 00:00:00 EST 2022
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
Pharmaceutical biology
He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X
Thu Dec 01 00:00:00 EST 2022
Yiqi Huoxue Tongluo recipe regulates NR4A1 to improve renal mitochondrial function in unilateral ureteral obstruction (UUO) rats.
Pharmaceutical biology
He Z,Zhang M,Xu H,Zhou W,Xu C,Wang Z,He M,Wang X
Thu Dec 01 00:00:00 EST 2022
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Oxidative medicine and cellular longevity
Chen J,Cui Z,Wang Y,Lyu L,Feng C,Feng D,Cheng Y,Li Z,Sun S
Thu Mar 24 00:00:00 EDT 2022
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Oxidative medicine and cellular longevity
Wang M,Yang X,Zhou Q,Guo Y,Chen Y,Song L,Yang J,Li L,Luo L
Mon Nov 28 00:00:00 EST 2022
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Oxidative medicine and cellular longevity
Wang M,Yang X,Zhou Q,Guo Y,Chen Y,Song L,Yang J,Li L,Luo L
Mon Nov 28 00:00:00 EST 2022
Biotransformation of graphene oxide within lung fluids could intensify its synergistic biotoxicity effect with cadmium by inhibiting cellular efflux of cadmium.
Environmental pollution (Barking, Essex : 1987)
Zhu J,Liu L,Ma J,Fu Q,Zheng Z,Du E,Xu Y,Zhang Z
Mon Aug 01 00:00:00 EDT 2022
Glis2 inhibits the epithelial-mesenchymal transition and apoptosis of renal tubule cells by regulating the β-catenin signalling pathway in diabetic kidney disease.
Biochemical and biophysical research communications
He L,Li Q,Du C,Xue Y,Yu P
Sat Jun 04 00:00:00 EDT 2022
Glis2 inhibits the epithelial-mesenchymal transition and apoptosis of renal tubule cells by regulating the β-catenin signalling pathway in diabetic kidney disease.
Biochemical and biophysical research communications
He L,Li Q,Du C,Xue Y,Yu P
Sat Jun 04 00:00:00 EDT 2022
CSTF2 Acts as a Prognostic Marker Correlated with Immune Infiltration in Hepatocellular Carcinoma.
Cancer management and research
Zhang W,Wan Y,Zhang Y,Liu Q,Zhu X
Tue Sep 20 00:00:00 EDT 2022
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Frontiers in pharmacology
Shi B,Xu FF,Xiang CP,Li CY,Fan P,Wang H
Fri Apr 01 00:00:00 EDT 2022
Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways.
Pharmacological research
Cai J,Liang J,Zhang Y,Shen L,Lin H,Hu T,Zhan S,Xie M,Liang S,Xian M,Wang S
Wed Jun 01 00:00:00 EDT 2022
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injuryanti-inflammatory and anti-apoptosis.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Liping Y,Xinglin YU,Chao Z,Pu C,Xiaohua D
Sat Oct 01 00:00:00 EDT 2022
Grifola frondosa Polysaccharide Ameliorates Early Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway.
Applied biochemistry and biotechnology
Jiang T,Shen S,Wang L,Zhao M,Li Y,Huang S
Thu Sep 01 00:00:00 EDT 2022
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Chemosphere
Zhou X,Song L,Cong R,Luan J,Zhou X,Wang Y,Yao L,Zhang X,Ren X,Zhang T,Yu M,Song N
Thu Dec 01 00:00:00 EST 2022
Toll-like receptor 4 deficiency alleviates lipopolysaccharide-induced intestinal barrier dysfunction.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhan L,Zheng J,Meng J,Fu D,Pang L,Ji C
Tue Nov 01 00:00:00 EDT 2022
Improvement of anticancer effect of berberine by salt formation modifications.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xu F,Liu M,Liao Y,Zhou Y,Zhang P,Zeng Y,Liu Z
Thu Sep 01 00:00:00 EDT 2022
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
BioMed research international
Qiu Y,Li C,Zhang B
Fri Apr 08 00:00:00 EDT 2022
Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dai C,Li M,Sun T,Zhang Y,Wang Y,Shen Z,Velkov T,Tang S,Shen J
Sun May 01 00:00:00 EDT 2022
Colistin-induced pulmonary toxicity involves the activation of NOX4/TGF-β/mtROS pathway and the inhibition of Akt/mTOR pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Dai C,Li M,Sun T,Zhang Y,Wang Y,Shen Z,Velkov T,Tang S,Shen J
Sun May 01 00:00:00 EDT 2022
Role of Mydgf in the regulation of hypoxia/reoxygenation-induced apoptosis in cardiac microvascular endothelial cells.
In vitro cellular & developmental biology. Animal
Wang Y,Zhang Y,Li J,Zhao R,Long X,Li C,Liu W,Chen W,Shi B
Thu Sep 01 00:00:00 EDT 2022
LncRNA SOX2OT facilitates LPS-induced inflammatory injury by regulating intercellular adhesion molecule 1 (ICAM1) via sponging miR-215-5p.
Clinical immunology (Orlando, Fla.)
Zhu W,Peng F,Cui X,Li J,Sun C
Sun May 01 00:00:00 EDT 2022
High-frequency repetitive transcranial magnetic stimulation mitigates depression-like behaviors in CUMS-induced rats via FGF2/FGFR1/p-ERK signaling pathway.
Brain research bulletin
Yan J,Zhang F,Niu L,Wang X,Lu X,Ma C,Zhang C,Song J,Zhang Z
Wed Jun 01 00:00:00 EDT 2022
Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF.
Aging
Jiang XL,Tai H,Kuang JS,Zhang JY,Cui SC,Lu YX,Qi SB,Zhang SY,Li SM,Chen JP,Meng XS
Thu Oct 27 00:00:00 EDT 2022
6-Hydroxydopamine-Induced Neurotoxicity in Rat Model of Parkinson's Disease: Is Reversed via Anti-Oxidative Activities of Curcumin and Aerobic Exercise Therapy.
Physiological research
Sokouti H,Mohajeri D,Nourazar MA
Wed Aug 31 00:00:00 EDT 2022
Sevelamer arsenite nanoparticle as a Pi-responsive drug carrier and embolic agent for chemoembolization.
Drug delivery
Bi QC,Tang JJ,Zhao J,Lv YF,Deng ZQ,Chen H,Xu YH,Xie CS,Liang QR,Luo RG,Tang Q
Thu Dec 01 00:00:00 EST 2022
Molecular Mechanism of Aluminum-Induced Oxidative Damage and Apoptosis in Rat Cardiomyocytes.
Biological trace element research
Zhou L,He M,Li X,Lin E,Wang Y,Wei H,Wei X
Sat Jan 01 00:00:00 EST 2022
Hyperglycemia promotes myocardial dysfunction via the ERS-MAPK10 signaling pathway in db/db mice.
Laboratory investigation; a journal of technical methods and pathology
Deng YW,Liu F,Li ZT,Gao JH,Zhao Y,Yang XL,Xia YL
Tue Nov 01 00:00:00 EDT 2022
Maltol Promotes Mitophagy and Inhibits Oxidative Stress via the Nrf2/PINK1/Parkin Pathway after Spinal Cord Injury.
Oxidative medicine and cellular longevity
Mao Y,Du J,Chen X,Al Mamun A,Cao L,Yang Y,Mubwandarikwa J,Zaeem M,Zhang W,Chen Y,Dai Y,Xiao J,Ye K
Fri Mar 18 00:00:00 EDT 2022
Enhanced autophagy promotes radiosensitivity by mediating Sirt1 downregulation in RM-1 prostate cancer cells.
Biochemical and biophysical research communications
Wang KX,Yan C,Yang X,Zhu PY,Cui WW,Ye C,Hu K,Lan T,Huang LY,Wang W,Ma P,Qi SH,Gu B,Luo L
Sat Jun 18 00:00:00 EDT 2022
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin.
Journal of nanobiotechnology
Yang XX,Xu X,Wang MF,Xu HZ,Peng XC,Han N,Yu TT,Li LG,Li QR,Chen X,Wen Y,Li TF
Sat May 14 00:00:00 EDT 2022
Hesperidin partly ameliorates the decabromodiphenyl ether-induced reproductive toxicity in pubertal mice.
Environmental science and pollution research international
Li S,Che S,Chen S,Ruan Z,Zhang L
Thu Dec 01 00:00:00 EST 2022
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Biological trace element research
Xiong Y,Li J,He S
Tue Feb 01 00:00:00 EST 2022
Cystathionine β-Synthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells.
Oxidative medicine and cellular longevity
Jiang QY,Li JM,Jing MR,Zhang YX,Zhang QQ,Cai CB,Wang D,Qi HW,Li T,Li YZ,Ji XY,Wu DD
Fri Jul 08 00:00:00 EDT 2022
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Cell death & disease
Song S,Shi C,Bian Y,Yang Z,Mu L,Wu H,Duan H,Shi Y
Sat Jul 30 00:00:00 EDT 2022
Interleukin-4 activates the PI3K/AKT signaling to promote apoptosis and inhibit the proliferation of granulosa cells.
Experimental cell research
Han Y,Yao R,Yang Z,Li S,Meng W,Zhang Y,Zhang Y,Luo H
Tue Mar 01 00:00:00 EST 2022
Bone-targeted nanoplatform enables efficient modulation of bone tumor microenvironment for prostate cancer bone metastasis treatment.
Drug delivery
Zhang X,Liu Q,Zhang T,Gao P,Wang H,Yao L,Huang J,Jiang S
Thu Dec 01 00:00:00 EST 2022
A mitochondria-targeted nano-platform for pancreatic cancer therapy.
Frontiers in chemistry
Tan X,Zhu X,Xu D,Shi Y,Wang Z,Cao M,Hu K,Zhao L,Zhao J,Miao M,Zeng H,Wu X
Tue Oct 11 00:00:00 EDT 2022
Calenduloside E alleviates cerebral ischemia/reperfusion injury by preserving mitochondrial function.
Journal of molecular histology
Li J,Bu Y,Li B,Zhang H,Guo J,Hu J,Zhang Y
Mon Aug 01 00:00:00 EDT 2022
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Toxicology
Zhou X,Wang S,Zhou R,Zhang T,Wang Y,Zhang Q,Cong R,Ji C,Luan J,Yao L,Zhou X,Song N
Wed Jun 15 00:00:00 EDT 2022
Anticancer effects of myricetin derivatives in non-small cell lung cancer in vitro and in vivo.
Pharmacology research & perspectives
Li M,Zha G,Chen R,Chen X,Sun Q,Jiang H
Tue Feb 01 00:00:00 EST 2022
Artemisia capillaris Thunb. water extract attenuates adriamycin-induced renal injury by regulating apoptosis through the ROS/MAPK axis.
Journal of food biochemistry
Huang G,Zhu Y,Yong C,Tian F,Liu L,Wu Q,Shu Y,Yao M,Tang C,Wang X,Chen W,Zhou E
Tue Feb 01 00:00:00 EST 2022
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Brain research
Zhang N,Shentu Y,Zhu M,Wang H,Yin X,Du C,Xue F,Fan J,Gong Y,Fan X
Thu Dec 15 00:00:00 EST 2022
Oxycodone relieves permeability damage and apoptosis of oxygen-glucose deprivation/reoxygenation-induced brain microvascular endothelial cells through ras homolog family member A (RhoA)/ Rho-associated coiled-coil containing kinases (ROCK)/ myosin light chain 2 (MLC2) signal.
Bioengineered
Shao F,Han D,Shen Y,Bian W,Zou L,Hu Y,Sun W
Tue Mar 01 00:00:00 EST 2022
Effect of NMB-regulated ERK1/2 and p65 signaling pathway on proliferation and apoptosis of cervical cancer.
Pathology, research and practice
Zeng R,Xiong X
Sat Oct 01 00:00:00 EDT 2022
Limosilactobacillus reuteri SLZX19-12 Protects the Colon from Infection by Enhancing Stability of the Gut Microbiota and Barrier Integrity and Reducing Inflammation.
Microbiology spectrum
Wu J,Lin Z,Wang X,Zhao Y,Zhao J,Liu H,Johnston LJ,Lu L,Ma X
Wed Jun 29 00:00:00 EDT 2022
Cangfudaotan decoction inhibits mitochondria-dependent apoptosis of granulosa cells in rats with polycystic ovarian syndrome.
Frontiers in endocrinology
Jiang XL,Tai H,Xiao XS,Zhang SY,Cui SC,Qi SB,Hu DD,Zhang LN,Kuang JS,Meng XS,Li SM
Tue Dec 06 00:00:00 EST 2022
Reducing oxidative stress may be important for treating pirarubicin-induced cardiotoxicity with schisandrin B.
Experimental and therapeutic medicine
Tang H,Zhao J,Feng R,Pu P,Wen L
Sat Jan 01 00:00:00 EST 2022
Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhu H,Zhang L,Jia H,Xu L,Cao Y,Zhai M,Li K,Xia L,Jiang L,Li X,Zhou Y,Liu J,Yu S,Duan W
Thu Sep 01 00:00:00 EDT 2022
Delta Opioid Peptide Targets Brain Microvascular Endothelial Cells Reducing Apoptosis to Relieve Hypoxia-Ischemic/Reperfusion Injury.
Pharmaceutics
Zhang R,Chen M,Deng Z,Kong L,Shen B,Zhang L
Fri Dec 23 00:00:00 EST 2022
Electroacupuncture at Zusanli Alleviates Sepsis by Regulating the TLR4-MyD88-NF-Kappa B Pathway and Diversity of Intestinal Flora.
Evidence-based complementary and alternative medicine : eCAM
Zhan L,Liu H,Zheng J,Meng J,Fu D,Pang L,Ji C
Sat Jul 16 00:00:00 EDT 2022
Dietary Nε-(carboxymethyl) lysine affects cardiac glucose metabolism and myocardial remodeling in mice.
World journal of diabetes
Wang ZQ,Sun Z
Tue Nov 15 00:00:00 EST 2022
Human umbilical vein endothelial cells-derived exosomes enhance cardiac function after acute myocardial infarction by activating the PI3K/AKT signaling pathway.
Bioengineered
Liu W,Feng Y,Wang X,Ding J,Li H,Guan H,Chen Z
Fri Apr 01 00:00:00 EDT 2022
miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1.
Environmental toxicology
Xin X,Duan L,Yang H,Yu H,Bao Y,Jia D,Wu N,Qiao Y
Fri Apr 01 00:00:00 EDT 2022
PTS is activated by ATF4 and promotes lung adenocarcinoma development via the Wnt pathway.
Translational lung cancer research
Ma W,Wang C,Li R,Han Z,Jiang Y,Zhang X,Divisi D,Capobianco E,Zhang L,Dong W
Thu Sep 01 00:00:00 EDT 2022
HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death.
Viruses
Saro A,Gao Z,Kambey PA,Li M,Huang J
Thu Dec 15 00:00:00 EST 2022
Asafoetida exerts neuroprotective effect on oxidative stress induced apoptosis through PI3K/Akt/GSK3β/Nrf2/HO-1 pathway.
Chinese medicine
Huang Q,Zhang C,Dong S,Han J,Qu S,Xie T,Zhao H,Shi Y
Wed Jul 06 00:00:00 EDT 2022
TDAG51-Deficiency Podocytes are Protected from High-Glucose-Induced Damage Through Nrf2 Activation via the AKT-GSK-3β Pathway.
Inflammation
Liu C,Li Y,Wang X
Mon Aug 01 00:00:00 EDT 2022
Colchicine improves severe acute pancreatitis-induced acute lung injury by suppressing inflammation, apoptosis and oxidative stress in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang D,Li L,Li J,Wei Y,Tang J,Man X,Liu F
Thu Sep 01 00:00:00 EDT 2022
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Journal of cellular and molecular medicine
Tai H,Tong YJ,Yu R,Yu Y,Yao SC,Li LB,Liu Y,Cui XZ,Kuang JS,Meng XS,Jiang XL
Wed Jun 01 00:00:00 EDT 2022
A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarction.
Journal of cellular and molecular medicine
Tai H,Tong YJ,Yu R,Yu Y,Yao SC,Li LB,Liu Y,Cui XZ,Kuang JS,Meng XS,Jiang XL
Wed Jun 01 00:00:00 EDT 2022
OL-FS13 alleviates experimental cerebral ischemia-reperfusion injury.
Experimental neurology
Liu N,Li Y,Yang Y,Shu L,Liu Y,Wu Y,Sun D,Kang Z,Zhang Y,Ni D,Wei Z,Li S,Yang M,Wang Y,Sun J,Yang X
Tue Nov 01 00:00:00 EDT 2022
Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents.
Journal of inorganic biochemistry
Wu Y,Liu J,Shao M,Zhang P,Song S,Yang G,Liu X,Liu Z
Mon Aug 01 00:00:00 EDT 2022
Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole.
BioMed research international
Pang W,Lu S,Zheng R,Li X,Yang S,Feng Y,Wang S,Guo J,Zhou S
Tue Sep 13 00:00:00 EDT 2022
Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole.
BioMed research international
Pang W,Lu S,Zheng R,Li X,Yang S,Feng Y,Wang S,Guo J,Zhou S
Tue Sep 13 00:00:00 EDT 2022
HIF-1α mediates renal fibrosis by regulating metabolic remodeling of renal tubule epithelial cells.
Biochemical and biophysical research communications
Liu D,Sun H,Li K,Zhao Z,Liu Z,Zhang G,Ge Y,Zhang J,Wang D,Leng Y
Sat Aug 27 00:00:00 EDT 2022
Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK/AKT Signaling Pathway.
Neuroscience
Yang XJ,Ling S,Zhou ML,Deng HJ,Qi M,Liu XL,Zhen C,Chen YX,Fan XR,Wu ZY,Ma FC,Rong J,Di GF,Jiang XC
Fri Jul 01 00:00:00 EDT 2022
Melatonin Attenuates Ropivacaine-Induced Apoptosis by Inhibiting Excessive Mitophagy Through the Parkin/PINK1 Pathway in PC12 and HT22 Cells.
Inflammation
Zeng L,He J,Liu C,Zhang F,Zhang Z,Chen H,Wang Q,Ding X,Luo H
Fri Apr 01 00:00:00 EDT 2022
Cinnamomi Ramulus inhibits the growth of colon cancer cells via Akt/ERK signaling pathways.
Chinese medicine
Pan B,Xia Y,Gao Z,Zhao G,Wang L,Fang S,Liu L,Yan S
Wed Mar 09 00:00:00 EST 2022
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Experimental cell research
Chen D,Jiang X
Sun May 01 00:00:00 EDT 2022
Fecal Microbiota Transplantation Alleviated Cerebral Ischemia Reperfusion Injury in Obese Rats.
The Tohoku journal of experimental medicine
Xie T,Yang R,Zhang X,Shen X,Yu L,Liao J,Bao T,Fang Q
Wed Dec 14 00:00:00 EST 2022
Hydrogen sulfide against preeclampsia exposure-induced oxidative mitochondrial damage in HTR-8/SVneo cells.
Frontiers in cardiovascular medicine
Wang X,Yu S,Jian Y,Pan H,Guo J,Wu J,Guo W
Fri Nov 18 00:00:00 EST 2022
DR1 activation promotes vascular smooth muscle cell apoptosis via up-regulation of CSE/H2 S pathway in diabetic mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Wen X,Xi Y,Zhang Y,Jiao L,Shi S,Bai S,Sun F,Chang G,Wu R,Hao J,Li H
Sat Jan 01 00:00:00 EST 2022
Stomatin-like protein-2 attenuates macrophage pyroptosis and H9c2 cells apoptosis by protecting mitochondrial function.
Biochemical and biophysical research communications
Fan R,Jiang H,Hu Y,Xu Y,Zhou Y,Chen G,Liu Y,Yao Y,Qin W,Chen W,Huang F,Chen X
Sun Dec 25 00:00:00 EST 2022
Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy.
Cell death & disease
Yi L,Shang XJ,Lv L,Wang Y,Zhang J,Quan C,Shi Y,Liu Y,Zhang L
Sat Nov 05 00:00:00 EDT 2022
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses.
Nature communications
Wang X,Liu Y,Xue C,Hu Y,Zhao Y,Cai K,Li M,Luo Z
Wed Sep 28 00:00:00 EDT 2022
Overexpression of C9orf72 exacerbates Aβ25‑35‑induced oxidative stress and apoptosis in PC12 cells.
Acta neurobiologiae experimentalis
Chen J,Zhang M,Bai H,Shi P,Du M,Zhang S,Lou J
Mon Apr 25 00:00:00 EDT 2022
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
International journal of molecular sciences
Zhao Y,Lin J,Li J,Bwalya C,Xu Y,Niu Y,Zhang Y,Wu J,Xu Y,Chen J,Ye S,Lin L
Tue Oct 18 00:00:00 EDT 2022
Comprehensive analysis of hypoxia-related genes for prognosis value, immune status, and therapy in osteosarcoma patients.
Frontiers in pharmacology
Han T,Wu Z,Zhang Z,Liang J,Xia C,Yan H
Wed Feb 01 00:00:00 EST 2023
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhou Y,Lu Q
Thu Sep 01 00:00:00 EDT 2022
Mechanism of HSP90 Inhibitor in the Treatment of DSS-induced Colitis in Mice by Inhibiting MAPK Pathway and Synergistic Effect of Compound Sophora Decoction.
Current pharmaceutical design
Yuan Y,Wu H,Shuai B,Liu C,Zhu F,Gao F,Wei C,Fan H
Fri Jan 06 00:00:00 EST 2023
BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.
Journal of Cancer
Luo Y,Wang X,Niu W,Zhou Y,Li M,Ma J,Yang J,Fan S,Zeng Z,Xiong W,Li X,Li G,Xiao J,Zhou M
Tue Apr 05 00:00:00 EDT 2022
Para‑hydroxybenzaldehyde against transient focal cerebral ischemia in rats via mitochondrial preservation.
Experimental and therapeutic medicine
Xiao T,Yang L,Chen P,Duan X
Thu Dec 01 00:00:00 EST 2022
MiR-145 inhibits the differentiation and proliferation of bone marrow stromal mesenchymal stem cells by GABARAPL1 in steroid-induced femoral head necrosis.
BMC musculoskeletal disorders
Xu P,Chang J,Ma G,Liao F,Xu T,Wu Y,Yin Z
Sat Nov 26 00:00:00 EST 2022
Anti-aging effect of phlorizin on D-galactose-induced aging in mice through antioxidant and anti-inflammatory activity, prevention of apoptosis, and regulation of the gut microbiota.
Experimental gerontology
Chen H,Dong L,Chen X,Ding C,Hao M,Peng X,Zhang Y,Zhu H,Liu W
Wed Jun 15 00:00:00 EDT 2022
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress.
International journal of endocrinology
Mu L,Chen N,Chen Y,Yang Z,Zhou H,Song S,Shi Y
Tue Oct 04 00:00:00 EDT 2022
Curculigoside mitigates hepatic ischemia/reperfusion-induced oxidative stress, inflammation, and apoptosis via activation of the Nrf-2/HO-1 pathway.
Human & experimental toxicology
Du P,Zhang X,Luo K,Li Y,Fu C,Xiao J,Xiao Q
Mon Apr 04 00:00:00 EDT 2022
The neuroprotective effects of phosphocreatine on amyloid beta 25-35-induced differentiated neuronal cell death through inhibition of AKT/GSK-3β /Tau/APP/CDK5 pathways in vivo and vitro.
Free radical biology & medicine
Ai J,Wang H,Chu P,Shopit A,Niu M,Ahmad N,Tesfaldet T,Wang FH,Fang JN,Li X,Tang SJ,Han QJ,Han G,Peng J,Tang Z
Tue Feb 01 00:00:00 EST 2022
Phenolic Acids from Fructus Chebulae Immaturus Alleviate Intestinal Ischemia-Reperfusion Injury in Mice through the PPARα/NF-κB Pathway.
Molecules (Basel, Switzerland)
Liu J,Li B,Liu J,Qiu F,Diao Y,Lei Y,Liu J,Zhang W
Tue Aug 16 00:00:00 EDT 2022
An EPO-loaded multifunctional hydrogel synergizing with adipose-derived stem cells restores neurogenic erectile function via enhancing nerve regeneration and penile rehabilitation.
Bioengineering & translational medicine
Shao J,Nie P,Yang W,Guo R,Ding D,Liang R,Wei B,Wei H
Thu Sep 01 00:00:00 EDT 2022
Dexmedetomidine Can Enhance PINK1/Parkin-Mediated Mitophagy in MPTP-Induced PD Mice Model by Activating AMPK.
Oxidative medicine and cellular longevity
Chen C,Chen Y,Liu T,Song D,Ma D,Cheng O
Tue May 10 00:00:00 EDT 2022
Blockage of Fibronectin 1 Ameliorates Myocardial Ischemia/Reperfusion Injury in Association with Activation of AMP-LKB1-AMPK Signaling Pathway.
Oxidative medicine and cellular longevity
Zhang YL,Li PB,Han X,Zhang B,Li HH
Tue May 24 00:00:00 EDT 2022
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Food & function
Liu Y,Huang H,Xu Z,Xue Y,Zhang D,Zhang Y,Li W,Li X
Mon Mar 07 00:00:00 EST 2022
β-Carotene Attenuates Apoptosis and Autophagy via PI3K/AKT/mTOR Signaling Pathway in Necrotizing Enterocolitis Model Cells IEC-6.
Evidence-based complementary and alternative medicine : eCAM
Xu G,Ma T,Zhou C,Zhao F,Peng K,Li B
Sat Jul 16 00:00:00 EDT 2022
Engeletin Alleviates the Inflammation and Apoptosis in Intervertebral Disc Degeneration via Inhibiting the NF-κB and MAPK Pathways.
Journal of inflammation research
Li B,Yang X,Zhang P,Guo J,Rong K,Wang X,Cao X,Zhou T,Zhao J
Sat Oct 15 00:00:00 EDT 2022
Yangjing Zhongyu decoction facilitates mitochondrial activity, estrogenesis, and energy metabolism in H2O2-induced human granulosa cell line KGN.
Journal of ethnopharmacology
Liu J,Shi D,Ma Q,Zhao P
Thu Sep 15 00:00:00 EDT 2022
IL-17A promotes lung fibrosis through impairing mitochondrial homeostasis in type II alveolar epithelial cells.
Journal of cellular and molecular medicine
Xiao H,Peng L,Jiang D,Liu Y,Zhu L,Li Z,Geng J,Xie B,Huang X,Wang J,Dai H,Wang C
Tue Nov 01 00:00:00 EDT 2022
Ssc-MiR-21-5p and Ssc-MiR-615 Regulates the Proliferation and Apoptosis of Leydig Cells by Targeting SOX5.
Cells
Tang Q,Zhang Y,Yue L,Ren H,Pan C
Thu Jul 21 00:00:00 EDT 2022
Smad7 Is Highly Expressed in Human Degenerative Discs and Participates in IL-1β-Induced Apoptosis of Rat AF Cells via the Mitochondria Pathway.
Oxidative medicine and cellular longevity
Li B,Lu ZY,Jiang SD,Jiang LS,Zheng XF
Fri Jul 08 00:00:00 EDT 2022
Ras-related protein Rab-20 inhibition alleviates cerebral ischemia/reperfusion injury by inhibiting mitochondrial fission and dysfunction.
Frontiers in molecular neuroscience
Guo J,Zhang L,Bu Y,Li W,Hu J,Li J
Fri Nov 18 00:00:00 EST 2022
Recombinant porcine beta defensin 2 alleviates inflammatory responses induced by Escherichia coli in IPEC-J2 cells.
International journal of biological macromolecules
Zhang K,Lian S,Shen X,Zhao X,Zhao W,Li C
Tue May 31 00:00:00 EDT 2022
Nephrotoxicity evaluation of 3-monochloropropane-1,2-diol exposure in Sprague-Dawley rats using data-independent acquisition-based quantitative proteomics analysis.
Toxicology letters
Jin C,Min F,Zhong Y,Sun D,Luo R,Liu Q,Peng X
Tue Mar 01 00:00:00 EST 2022
Subchronic Oral Cylindrospermopsin Exposure Alters the Host Gut Microbiome and Is Associated with Progressive Hepatic Inflammation, Stellate Cell Activation, and Mild Fibrosis in a Preclinical Study.
Toxins
Saha P,Upright M,Bose D,Roy S,Trivedi A,More M,Scott GI,Brooks BW,Chatterjee S
Thu Dec 01 00:00:00 EST 2022
Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics.
International journal of biological sciences
Zhang Q,Luo P,Chen J,Yang C,Xia F,Zhang J,Tang H,Liu D,Gu L,Shi Q,He X,Yang T,Wang J
Fri Apr 15 00:00:00 EDT 2022
Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis.
Oxidative medicine and cellular longevity
Yang F,Zhang Y,Liu S,Xiao J,He Y,Shao Z,Zhang Y,Cai X,Xiong L
Thu Mar 24 00:00:00 EDT 2022
Nonylphenol inhibited HIF-1alpha regulated aerobic glycolysis and induced ROS mediated apoptosis in rat Sertoli cells.
Ecotoxicology and environmental safety
Jiang Q,Di Q,Shan D,Xu Q
Mon Aug 01 00:00:00 EDT 2022
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice.
Journal of molecular and cellular cardiology
Liu F,Deng Y,Zhao Y,Li Z,Gao J,Zhang Y,Yang X,Liu Y,Xia Y
Fri Jul 01 00:00:00 EDT 2022
Acupuncture Relieves Stress-Induced Depressive Behavior by Reducing Oxidative Stress and Neuroapoptosis in Rats.
Frontiers in behavioral neuroscience
Cheng WJ,Li P,Huang WY,Huang Y,Chen WJ,Chen YP,Shen JL,Chen JK,Long NS,Meng XJ
Sat Jan 22 00:00:00 EST 2022
SIRT1 Deacetylates TET2 and Promotes Its Ubiquitination Degradation to Achieve Neuroprotection Against Parkinson's Disease.
Frontiers in neurology
Li X,Liu T,Wu TT,Feng Y,Peng SJ,Yin H,Wu YC
Tue May 04 00:00:00 EDT 2021
The Potential Protective Effect and Possible Mechanism of Peptides from Oyster (Crassostrea hongkongensis) Hydrolysate on Triptolide-Induced Testis Injury in Male Mice.
Marine drugs
Zhang X,Peng Z,Zheng H,Zhang C,Lin H,Qin X
Sat Oct 09 00:00:00 EDT 2021
Morroniside protects OLN-93 cells against H2O2-induced injury through the PI3K/Akt pathway-mediated antioxidative stress and antiapoptotic activities.
Cell cycle (Georgetown, Tex.)
Li F,Song X,Xu J,Shi Y,Hu R,Ren Z,Qi Q,Lü H,Cheng X,Hu J
Thu Apr 01 00:00:00 EDT 2021
Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice.
Iranian journal of basic medical sciences
Xianchu L,Ming L,Changhao C,Beiwang D,Jingtao X
Wed Dec 01 00:00:00 EST 2021
Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity.
Nutrition & metabolism
Li P,Xia Z,Kong W,Wang Q,Zhao Z,Arnold A,Xu Q,Xu J
Thu Jun 24 00:00:00 EDT 2021
Erythropoietin Attenuates Experimental Contrast-Induced Nephrology: A Role for the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling Pathway.
Frontiers in medicine
Yang J,Zhou J,Wang X,Ji L,Wang S,Chen X,Yang L
Sun May 02 00:00:00 EDT 2021
Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts.
Cell calcium
Zhang S,Lu K,Yang S,Wu Y,Liao J,Lu Y,Wu Q,Zhao N,Dong Q,Chen L,Du Y
Wed Dec 01 00:00:00 EST 2021
The Effect of Hispidulin, a Flavonoid from Salvia plebeia, on Human Nasopharyngeal Carcinoma CNE-2Z Cell Proliferation, Migration, Invasion, and Apoptosis.
Molecules (Basel, Switzerland)
Dai Y,Sun X,Li B,Ma H,Wu P,Zhang Y,Zhu M,Li HM,Qin M,Wu CZ
Sun Mar 14 00:00:00 EST 2021
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas.
BMC endocrine disorders
Wang S,Wang A,Zhang Y,Zhu K,Wang X,Chen Y,Wu J
Tue Nov 23 00:00:00 EST 2021
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
BMC complementary medicine and therapies
Tai H,Jiang XL,Lan ZM,Li Y,Kong L,Yao SC,Song N,Lv MJ,Wu J,Yang P,Xiao XS,Yang GL,Kuang JS,Jia LQ
Mon Mar 22 00:00:00 EDT 2021
Methylation of miR-19b-3p promoter exacerbates inflammatory responses in sepsis-induced ALI via targeting KLF7.
Cell biology international
Jiang L,Wang M,Sun R,Lin Z,Liu R,Cai H,Tang Z,Zhang R
Sun Aug 01 00:00:00 EDT 2021
Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation.
BMC anesthesiology
Huang Y,Sun X,Juan Z,Zhang R,Wang R,Meng S,Zhou J,Li Y,Xu K,Xie K
Tue Apr 06 00:00:00 EDT 2021
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
Cell death & disease
Sun S,Duan Z,Wang X,Chu C,Yang C,Chen F,Wang D,Wang C,Li Q,Ding W
Fri Jun 11 00:00:00 EDT 2021
A SMOC2 variant inhibits BMP signaling by competitively binding to BMPR1B and causes growth plate defects.
Bone
Long F,Shi H,Li P,Guo S,Ma Y,Wei S,Li Y,Gao F,Gao S,Wang M,Duan R,Wang X,Yang K,Sun W,Li X,Li J,Liu Q
Fri Jan 01 00:00:00 EST 2021
Methylation of TMEM176A, a key ERK signaling regulator, is a novel synthetic lethality marker of ATM inhibitors in human lung cancer.
Epigenomics
Li H,Yang W,Zhang M,He T,Zhou F,G Herman J,Hu L,Guo M
Wed Sep 01 00:00:00 EDT 2021
VEGF-C/VEGFR-3 axis protects against pressure-overload induced cardiac dysfunction through regulation of lymphangiogenesis.
Clinical and translational medicine
Lin QY,Zhang YL,Bai J,Liu JQ,Li HH
Mon Mar 01 00:00:00 EST 2021
Cartilage endplate stem cells inhibit intervertebral disc degeneration by releasing exosomes to nucleus pulposus cells to activate Akt/autophagy.
Stem cells (Dayton, Ohio)
Luo L,Jian X,Sun H,Qin J,Wang Y,Zhang J,Shen Z,Yang D,Li C,Zhao P,Liu M,Tian Z,Zhou Y
Thu Apr 01 00:00:00 EDT 2021
Typical phthalic acid esters induce apoptosis by regulating the PI3K/Akt/Bcl-2 signaling pathway in rat insulinoma cells.
Ecotoxicology and environmental safety
Li L,Wang F,Zhang J,Wang K,De X,Li L,Zhang Y
Fri Jan 15 00:00:00 EST 2021
Polystyrene microplastics induce blood-testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats.
Environmental science and pollution research international
Li S,Wang Q,Yu H,Yang L,Sun Y,Xu N,Wang N,Lei Z,Hou J,Jin Y,Zhang H,Li L,Xu F,Zhang L
Wed Sep 01 00:00:00 EDT 2021
MicroRNA-211-5p attenuates spinal cord injury via targeting of activating transcription factor 6.
Tissue & cell
Zhang H,Piao M,Guo M,Meng L,Yu H
Mon Feb 01 00:00:00 EST 2021
Biochanin A Inhibits Glioblastoma Growth via Restricting Glycolysis and Mitochondrial Oxidative Phosphorylation.
Frontiers in oncology
Dong Q,Li Q,Duan L,Yin H,Wang X,Liu Y,Wang B,Li K,Yao X,Yuan G,Pan Y
Tue Nov 07 00:00:00 EST 2023
Maternally expressed 3 protects the intestinal barrier from cardiac arrest-induced ischemia/reperfusion injury via miR-34a-3p/sirtuin 1/nuclear factor kappa B signaling.
Annals of translational medicine
Huang X,Pan M,Du P,Chen Y,Zhang C,Lu W,Lin J
Fri Jan 01 00:00:00 EST 2021
Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways.
Frontiers in pharmacology
Xie B,Zeng Z,Liao S,Zhou C,Wu L,Xu D
Sat Oct 23 00:00:00 EDT 2021
Effect of Perinatal Vitamin D Deficiency on Lung Mesenchymal Stem Cell Differentiation and Injury Repair Potential.
American journal of respiratory cell and molecular biology
Sakurai R,Singh H,Wang Y,Harb A,Gornes C,Liu J,Rehan VK
Mon Nov 01 00:00:00 EDT 2021
LINC00857 contributes to proliferation and lymphomagenesis by regulating miR-370-3p/CBX3 axis in diffuse large B-cell lymphoma.
Carcinogenesis
Huang Y,Lin Y,Song X,Wu D
Fri May 28 00:00:00 EDT 2021
Role of Glycated High Mobility Group Box-1 in Gastric Cancer.
International journal of molecular sciences
Kishi S,Nishiguchi Y,Honoki K,Mori S,Fujiwara-Tani R,Sasaki T,Fujii K,Kawahara I,Goto K,Nakashima C,Kido A,Tanaka Y,Luo Y,Kuniyasu H
Thu May 13 00:00:00 EDT 2021
Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway.
Experimental and therapeutic medicine
Xu L,Zhu L,Liu P,Wu Z,Zou Z
Sun Aug 01 00:00:00 EDT 2021
Exploring the Critical Components and Therapeutic Mechanisms of Perilla frutescens L. in the Treatment of Chronic Kidney Disease via Network Pharmacology.
Frontiers in pharmacology
Yong C,Zhang Z,Huang G,Yang Y,Zhu Y,Qian L,Tian F,Liu L,Wu Q,Xu Z,Chen C,Zhao J,Gao K,Zhou E
Wed Dec 15 00:00:00 EST 2021
Role of the BDNF/TrkB/CREB signaling pathway in the cytotoxicity of bisphenol S in SK-N-SH cells.
Journal of biochemical and molecular toxicology
He QZ,Zhu BQ,Xu XN,Zeng HC
Tue Jun 01 00:00:00 EDT 2021
Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia/reperfusion injury through inhibiting ROS production from mitochondrial complex I.
Theranostics
Jiang L,Yin X,Chen YH,Chen Y,Jiang W,Zheng H,Huang FQ,Liu B,Zhou W,Qi LW,Li J
Mon Aug 16 00:00:00 EDT 2021
Apatinib combined with Keytruda treatment induces apoptosis of gastric carcinoma cells through CES4/miR-616-5p/DUSP2 axis.
Basic & clinical pharmacology & toxicology
Zhang F,Yin Y,Xu W,Zhou Z,Sun X,Li P
Mon Nov 01 00:00:00 EDT 2021
Identification of key microRNAs and the underlying molecular mechanism in spinal cord ischemia-reperfusion injury in rats.
PeerJ
Chen F,Han J,Wang D
Tue Jun 15 00:00:00 EDT 2021
Epigallocatechin-3-Gallate Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via Inhibition of Apoptosis and Promotion of Autophagy through the ROS/MAPK Signaling Pathway.
Oxidative medicine and cellular longevity
Wu D,Liu Z,Wang Y,Zhang Q,Li J,Zhong P,Xie Z,Ji A,Li Y
Fri May 28 00:00:00 EDT 2021
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Journal of controlled release : official journal of the Controlled Release Society
Qiu Y,Ren K,Zhao W,Yu Q,Guo R,He J,Mei L,Liu Y,Tang J,Xu S,Li J,Wei J,Li M,Zhang Z,He Q
Sun Jan 10 00:00:00 EST 2021
N-acetylcysteine ameliorate cytotoxic injury in piglets sertoli cells induced by zearalenone and deoxynivalenol.
Environmental science and pollution research international
Cao L,Zhao J,Xu J,Zhu L,Rahman SU,Feng S,Li Y,Wu J,Wang X
Mon Nov 01 00:00:00 EDT 2021
Improvement of sensory neuron growth and survival via negatively regulating PTEN by miR-21-5p-contained small extracellular vesicles from skin precursor-derived Schwann cells.
Stem cell research & therapy
Cong M,Shen M,Wu X,Li Y,Wang L,He Q,Shi H,Ding F
Mon Jan 25 00:00:00 EST 2021
Dynamic observation of 5-fluorouracil-induced myocardial injury and mitochondrial autophagy in aging rats.
Experimental and therapeutic medicine
Li Y,Zhang Y,Zhou X,Lei X,Li X,Wei L
Wed Dec 01 00:00:00 EST 2021
EphA2 inhibits SRA01/04 cells apoptosis by suppressing autophagy via activating PI3K/Akt/mTOR pathway.
Archives of biochemistry and biophysics
Han J,Wang L,Lv H,Liu J,Dong Y,Shi L,Ji Q
Sat Oct 30 00:00:00 EDT 2021
Salusin-β Mediates High Glucose-Induced Inflammation and Apoptosis in Retinal Capillary Endothelial Cells via a ROS-Dependent Pathway in Diabetic Retinopathy.
Diabetes, metabolic syndrome and obesity : targets and therapy
Wang H,Zhang M,Zhou H,Cao L,Zhou J,Chen Q,Zhang X
Sat Apr 23 00:00:00 EDT 2022
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade.
European journal of pharmacology
Zeng S,Chen L,Sun Q,Zhao H,Yang H,Ren S,Liu M,Meng X,Xu H
Sun Sep 05 00:00:00 EDT 2021
P53 inhibitor pifithrin-α inhibits ropivacaine-induced neuronal apoptosis via the mitochondrial apoptosis pathway.
Journal of biochemical and molecular toxicology
Zeng L,Zhang F,Zhang Z,Xu M,Xu Y,Liu Y,Xu H,Sun X,Sang M,Luo H
Sun Aug 01 00:00:00 EDT 2021
Vagal Nerve Stimulation Protects Against Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting Autophagy and Apoptosis.
Neuropsychiatric disease and treatment
Zhang LN,Zhang XW,Li CQ,Guo J,Chen YP,Chen SL
Thu Apr 21 00:00:00 EDT 2022
Curcumin attenuates Adriamycin-resistance of acute myeloid leukemia by inhibiting the lncRNA HOTAIR/miR-20a-5p/WT1 axis.
Laboratory investigation; a journal of technical methods and pathology
Liu JM,Li M,Luo W,Sun HB
Fri Oct 01 00:00:00 EDT 2021
Verapamil ameliorates proximal tubular epithelial cells apoptosis and fibrosis in diabetic kidney.
European journal of pharmacology
Song Y,Guo F,Zhao Y,Zhao L,Fan X,Zhang Y,Liu Y,Qin G
Mon Nov 15 00:00:00 EST 2021
Tanshinone IIA Combined With Cyclosporine A Alleviates Lung Apoptosis Induced by Renal Ischemia-Reperfusion in Obese Rats.
Frontiers in medicine
Tai H,Jiang XL,Song N,Xiao HH,Li Y,Cheng MJ,Yin XM,Chen YR,Yang GL,Jiang XY,Kuang JS,Lan ZM,Jia LQ
Sat May 22 00:00:00 EDT 2021
Dual-enzymatically cross-linked gelatin hydrogel promotes neural differentiation and neurotrophin secretion of bone marrow-derived mesenchymal stem cells for treatment of moderate traumatic brain injury.
International journal of biological macromolecules
Li J,Zhang D,Guo S,Zhao C,Wang L,Ma S,Guan F,Yao M
Thu Sep 30 00:00:00 EDT 2021
Senolytic therapy ameliorates renal fibrosis postacute kidney injury by alleviating renal senescence.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li C,Shen Y,Huang L,Liu C,Wang J
Fri Jan 01 00:00:00 EST 2021
Ixazomib inhibits myeloma cell proliferation by targeting UBE2K.
Biochemical and biophysical research communications
Wang Q,Dong Z,Su J,Huang J,Xiao P,Tian L,Chen Y,Ma L,Chen X
Fri Apr 16 00:00:00 EDT 2021
Insulin-like growth factor binding protein-1 regulates HIF-1α degradation to inhibit apoptosis in hypoxic cardiomyocytes.
Cell death discovery
Tang X,Jiang H,Lin P,Zhang Z,Chen M,Zhang Y,Mo J,Zhu Y,Liu N,Chen X
Thu Sep 16 00:00:00 EDT 2021
The Role of Potassium Channels in Chronic Stress-Induced Brain Injury.
Biological & pharmaceutical bulletin
Ren J,Guo J,Zhu S,Wang Q,Gao R,Zhao C,Feng C,Qin C,He Z,Qin C,Wang Z,Zang L
Mon Feb 01 00:00:00 EST 2021
Exosomal miR-27 negatively regulates ROS production and promotes granulosa cells apoptosis by targeting SPRY2 in OHSS.
Journal of cellular and molecular medicine
Liu K,Yang W,Hu M,Xie W,Huang J,Cui M,He X,Nie X
Thu Apr 01 00:00:00 EDT 2021
Gasdermin D Protects Mouse Podocytes Against High-Glucose-Induced Inflammation and Apoptosis via the C-Jun N-Terminal Kinase (JNK) Pathway.
Medical science monitor : international medical journal of experimental and clinical research
Li H,Zhao K,Li Y
Tue Mar 09 00:00:00 EST 2021
Anti-osteosarcoma effect of antiserum against cross antigen TPD52 between osteosarcoma and Trichinella spiralis.
Parasites & vectors
Yue TT,Zhang N,Li JH,Lu XY,Wang XC,Li X,Zhang HB,Cheng SQ,Wang BB,Gong PT,Zhang XC
Sun Sep 26 00:00:00 EDT 2021
Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.
PLoS pathogens
Xu S,Jiang N,Nawaz W,Liu B,Zhang F,Liu Y,Wu X,Wu Z
Sat May 01 00:00:00 EDT 2021
125I seed implantation brachytherapy for glottic carcinoma: an experimental and clinical study.
American journal of cancer research
Jiao D,Zhou X,Yao Y,Chen J,Lei Q,Ren J,Han X
Fri May 07 00:00:00 EDT 2021
125I seed implantation brachytherapy for glottic carcinoma: an experimental and clinical study.
American journal of cancer research
Jiao D,Zhou X,Yao Y,Chen J,Lei Q,Ren J,Han X
Fri May 07 00:00:00 EDT 2021
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species.
Molecular medicine reports
Fu Y,Ye Y,Zhu G,Xu Y,Sun J,Wu H,Feng F,Wen Z,Jiang S,Li Y,Zhang Q
Mon Mar 01 00:00:00 EST 2021
Ezrin Promotes the Proliferation, Migration, and Invasion of Ovarian Cancer Cells.
Biomedical and environmental sciences : BES
Li MJ,Xiong D,Huang H,Wen ZY
Sat Feb 20 00:00:00 EST 2021
Knockdown of enhancer of rudimentary homolog expression attenuates proliferation, cell cycle and apoptosis of melanoma cells.
Melanoma research
Xiao M,Tang N,Yan Y,Li Z,Shi S,He S,Chen Z,Cao K,Chen J,Zhou J,Chen X
Sun Aug 01 00:00:00 EDT 2021
miR-25-3p protects renal tubular epithelial cells from apoptosis induced by renal IRI by targeting DKK3.
Open life sciences
Zhang Y,Zuo X
Wed Nov 30 00:00:00 EST 2022
Grape seed proanthocyanidins protect PC12 cells from hydrogen peroxide-induced damage via the PI3K/AKT signaling pathway.
Neuroscience letters
He X,Guo X,Ma Z,Li Y,Kang J,Zhang G,Gao Y,Liu M,Chen H,Kang X
Sat Apr 17 00:00:00 EDT 2021
The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.
Journal of hazardous materials
Zhang S,Zhao X,Hao J,Zhu Y,Wang Y,Wang L,Guo S,Yi H,Liu Y,Liu J
Sat May 15 00:00:00 EDT 2021
Chloroquine enhances catalpol's ability to promote apoptosis by inhibiting catalpol's autophagy-promoting effect on gastric cancer.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology
Sun F,Wang Z,Wang X
Wed Dec 08 00:00:00 EST 2021
Neuroprotective effects of bone marrow Sca-1+ cells against age-related retinal degeneration in OPTN E50K mice.
Cell death & disease
Liu X,Hou M,Zhang S,Zhao Y,Wang Q,Jiang M,Du M,Shao Z,Yuan H
Tue Jun 15 00:00:00 EDT 2021
miR-142-3p and HMGB1 Are Negatively Regulated in Proliferation, Apoptosis, Migration, and Autophagy of Cartilage Endplate Cells.
Cartilage
Wang B,Ji D,Xing W,Li F,Huang Z,Zheng W,Xue J,Zhu Y,Yang X
Wed Dec 01 00:00:00 EST 2021
HIF-1/AKT Signaling-Activated PFKFB2 Alleviates Cardiac Dysfunction and Cardiomyocyte Apoptosis in Response to Hypoxia.
International heart journal
Gao J,Feng W,Lv W,Liu W,Fu C
Tue Mar 30 00:00:00 EDT 2021
Microarray analysis reveals a potential role of lncRNA expression in remote ischemic preconditioning in myocardial ischemia-reperfusion injury.
American journal of translational research
Lou Z,Wu W,Chen R,Xia J,Shi H,Ge H,Xue J,Wang H,Lin Z,Chu M,Zhao Q
Fri Nov 10 00:00:00 EST 2023
A novel histone deacetylase inhibitor LT-548-133-1 induces apoptosis by inhibiting HDAC and interfering with microtubule assembly in MCF-7 cells.
Investigational new drugs
Xue J,Wu G,Ejaz U,Akhtar F,Wan X,Zhu Y,Geng A,Chen Y,He S
Fri Oct 01 00:00:00 EDT 2021
Endophilin A2-mediated alleviation of endoplasmic reticulum stress-induced cardiac injury involves the suppression of ERO1α/IP3R signaling pathway.
International journal of biological sciences
Liu Y,Hu R,Shen H,Mo Q,Wang X,Zhang G,Li S,Liang G,Hou N,Luo J
Fri Feb 10 00:00:00 EST 2023
Study on Protection of Human Umbilical Vein Endothelial Cells from Amiodarone-Induced Damage by Intermedin through Activation of Wnt/β-Catenin Signaling Pathway.
Oxidative medicine and cellular longevity
Wang Y,Wang J,Yang J,Kang J,Xue F,Chang S,Ji H,Zang H,Zhou X,Wang G,Fan W,Yan X,Guo J,Ren X,Tian J
Wed Jan 19 00:00:00 EST 2022
Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation.
Chemico-biological interactions
Li C,Shi L,Peng C,Yu G,Zhang Y,Du Z
Mon Mar 01 00:00:00 EST 2021
OSU-03012 Disrupts Akt Signaling and Prevents Endometrial Carcinoma Progression in vitro and in vivo.
Drug design, development and therapy
Ding L,Ren C,Yang L,Wu Z,Li F,Jiang D,Zhu Y,Lu J
Thu Nov 04 00:00:00 EDT 2021
Erteng-Sanjie Capsule Enhances Chemosensitivity of 5-Fluorouracil in Tumor-Bearing Nude Mice with Gastric Cancer by Inhibiting Notch1/Hes1 Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Zhou J,Hao S,Guo H,Yu H,Guo Z,Liu L
Thu Jul 15 00:00:00 EDT 2021
Chrysophanol Relieves Cisplatin-Induced Nephrotoxicity via Concomitant Inhibition of Oxidative Stress, Apoptosis, and Inflammation.
Frontiers in physiology
Ma S,Xu H,Huang W,Gao Y,Zhou H,Li X,Zhang W
Mon Dec 27 00:00:00 EST 2021
Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response.
International immunopharmacology
Wang L,Wang X,Kong L,Wang S,Huang K,Wu J,Wang C,Sun H,Liu K,Meng Q
Mon Nov 01 00:00:00 EDT 2021
Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt.
American journal of physiology. Heart and circulatory physiology
Sun Z,Zhang L,Li L,Shao C,Liu J,Zhou M,Wang Z
Fri Jan 01 00:00:00 EST 2021
MicroRNA miR-188-5p as a mediator of long non-coding RNA MALAT1 regulates cell proliferation and apoptosis in multiple myeloma.
Bioengineered
Liu H,Chi Z,Jin H,Yang W
Wed Dec 01 00:00:00 EST 2021
Thymoquinone improves testicular damage and sperm quality in experimentally varicocele-induced adolescent rats.
Andrologia
Gur FM,Timurkaan S,Taskin E,Guven C,Gur HE,Senturk M,Dastan S,Nurdinov N,Unalan A,Cankut S,Tatyuz I
Tue Jun 01 00:00:00 EDT 2021
Hyaluronic acid/polyethyleneimine nanoparticles loaded with copper ion and disulfiram for esophageal cancer.
Carbohydrate polymers
Xu R,Zhang K,Liang J,Gao F,Li J,Guan F
Tue Jun 01 00:00:00 EDT 2021
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Cancer biology & medicine
Lyu G,Su P,Hao X,Chen S,Ren S,Zhao Z,Gong Y,Liu Q,Shao C
Mon Feb 15 00:00:00 EST 2021
Zirconia Nanoparticles Induce HeLa Cell Death Through Mitochondrial Apoptosis and Autophagy Pathways Mediated by ROS.
Frontiers in chemistry
Shang Y,Wang Q,Li J,Liu H,Zhao Q,Huang X,Dong H,Chen W,Gui R,Nie X
Sat Apr 03 00:00:00 EDT 2021
Empagliflozin alleviates ethanol-induced cardiomyocyte injury through inhibition of mitochondrial apoptosis via a SIRT1/PTEN/Akt pathway.
Clinical and experimental pharmacology & physiology
Tian G,Yu Y,Deng H,Yang L,Shi X,Yu B
Tue Jun 01 00:00:00 EDT 2021
Irisin Contributes to Neuroprotection by Promoting Mitochondrial Biogenesis After Experimental Subarachnoid Hemorrhage.
Frontiers in aging neuroscience
Tu T,Yin S,Pang J,Zhang X,Zhang L,Zhang Y,Xie Y,Guo K,Chen L,Peng J,Jiang Y
Tue Feb 23 00:00:00 EST 2021
Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway.
International journal of environmental health research
Zhou L,Wang S,Cao L,Ren X,Li Y,Shao J,Xu L
Fri Jan 01 00:00:00 EST 2021
Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis.
Cancer cell international
Zhang H,Yu Y,Wang J,Han Y,Ren T,Huang Y,Chen C,Huang Q,Wang W,Niu J,Lou J,Guo W
Thu Apr 01 00:00:00 EDT 2021
Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression.
Stem cell research & therapy
Yao C,Zhou Y,Wang H,Deng F,Chen Y,Zhu X,Kong Y,Pan L,Xue L,Zhou X,Shi C,Sheng X
Mon Aug 09 00:00:00 EDT 2021
Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression.
Stem cell research & therapy
Yao C,Zhou Y,Wang H,Deng F,Chen Y,Zhu X,Kong Y,Pan L,Xue L,Zhou X,Shi C,Sheng X
Mon Aug 09 00:00:00 EDT 2021
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Life sciences
Liu L,Yan LN,Sui Z
Fri Jan 15 00:00:00 EST 2021
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
International journal of pharmaceutics
Yuan SJ,Wang C,Xu HZ,Liu Y,Zheng MY,Li K,Sun SK,Komatsu N,Zhao L,Chen X
Sun Sep 05 00:00:00 EDT 2021
Gαi1 Promoted Proliferation, Migration and Invasion via Activating the Akt-mTOR/Erk-MAPK Signaling Pathway in Renal Cell Carcinoma.
OncoTargets and therapy
Chen Z,Zhang Y,Wu X,Zhang J,Xu W,Shen C,Zheng B
Fri Apr 22 00:00:00 EDT 2022
Saikosaponin D Inhibits the Proliferation and Promotes the Apoptosis of Rat Hepatic Stellate Cells by Inducing Autophagosome Formation.
Evidence-based complementary and alternative medicine : eCAM
Jiang H,Liu J,Zhang K,Zeng Q
Tue Apr 26 00:00:00 EDT 2022
Down-Regulating the Expression of miRNA-21 Inhibits the Glucose Metabolism of A549/DDP Cells and Promotes Cell Death Through the PI3K/AKT/mTOR/HIF-1α Pathway.
Frontiers in oncology
Sun Y,Liu W,Zhao Q,Zhang R,Wang J,Pan P,Shang H,Liu C,Wang C
Sun May 30 00:00:00 EDT 2021
Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.
Biochemical and biophysical research communications
Li Q,Luan Q,Zhu H,Zhao Y,Ji J,Wu F,Yan J
Fri Apr 30 00:00:00 EDT 2021
Emodin ameliorates acute pancreatitis-induced lung injury by suppressing NLRP3 inflammasome-mediated neutrophil recruitment.
Experimental and therapeutic medicine
Jiang N,Li Z,Luo Y,Jiang L,Zhang G,Yang Q,Chen H
Sun Aug 01 00:00:00 EDT 2021
Schisandrol A Attenuates Myocardial Ischemia/Reperfusion-Induced Myocardial Apoptosis through Upregulation of 14-3-3θ.
Oxidative medicine and cellular longevity
Gong S,Liu J,Wan S,Yang W,Zhang Y,Yu B,Li F,Kou J
Wed Jan 05 00:00:00 EST 2022
Secreted Frizzled-Related Protein 5 Protects Against Cardiac Rupture and Improves Cardiac Function Through Inhibiting Mitochondrial Dysfunction.
Frontiers in cardiovascular medicine
Huang X,Yan Y,Zheng W,Ma Y,Wang X,Gong W,Nie S
Wed Sep 29 00:00:00 EDT 2021
Hydroxychloroquine alleviates the neurotoxicity induced by anti-ribosomal P antibodies.
Journal of neuroimmunology
Zhao X,Yang P
Wed Sep 15 00:00:00 EDT 2021
Ophiocordyceps lanpingensis polysaccharides alleviate chronic kidney disease through MAPK/NF-κB pathway.
Journal of ethnopharmacology
Zhou S,He Y,Zhang W,Xiong Y,Jiang L,Wang J,Cui X,Qu Y,Ge F
Tue Aug 10 00:00:00 EDT 2021
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Frontiers in veterinary science
Ou G,Jiang X,Gao A,Li X,Lin Z,Pei S
Wed Feb 23 00:00:00 EST 2022
An Integrative Pharmacology-Based Strategy to Uncover the Mechanism of Xiong-Pi-Fang in Treating Coronary Heart Disease with Depression.
Frontiers in pharmacology
Zhang L,Zhang Y,Zhu M,Pei L,Deng F,Chen J,Zhang S,Cong Z,Du W,Xiao X
Wed Apr 21 00:00:00 EDT 2021
A New Chalcone Derivative C49 Reverses Doxorubicin Resistance in MCF-7/DOX Cells by Inhibiting P-Glycoprotein Expression.
Frontiers in pharmacology
Wang T,Dong J,Yuan X,Wen H,Wu L,Liu J,Sui H,Deng W
Sun May 02 00:00:00 EDT 2021
Baicalin Attenuates Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron-Astrocyte Cocultures.
Frontiers in pharmacology
Li C,Sui C,Wang W,Yan J,Deng N,Du X,Cheng F,Ma X,Wang X,Wang Q
Fri Jul 09 00:00:00 EDT 2021
Downregulation of TAF9B by miR-7-5p Inhibits the Progression of Osteosarcoma.
OncoTargets and therapy
Gu W,Chen P,Ren P,Wang Y,Li X,Gong M
Fri Apr 22 00:00:00 EDT 2022
Discovering and Characterizing of Survivin Dominant Negative Mutants With Stronger Pro-apoptotic Activity on Cancer Cells and CSCs.
Frontiers in oncology
Guo W,Ma X,Fu Y,Liu C,Liu Q,Hu F,Miao H,Zhang T,Liu Y,Han MH,You F,Yang Y,Zheng W
Wed Apr 21 00:00:00 EDT 2021
Clemastine Fumarate Attenuates Myocardial Ischemia Reperfusion Injury Through Inhibition of Mast Cell Degranulation.
Frontiers in pharmacology
Meng S,Sun X,Juan Z,Wang M,Wang R,Sun L,Li Y,Xin A,Li S,Li Y
Tue Sep 14 00:00:00 EDT 2021
Vascular endothelial cell-secreted exosomes facilitate osteoarthritis pathogenesis by promoting chondrocyte apoptosis.
Aging
Yang RZ,Zheng HL,Xu WN,Zheng XF,Li B,Jiang LS,Jiang SD
Mon Feb 01 00:00:00 EST 2021
Gastrodin protects against high glucose-induced cardiomyocyte toxicity via GSK-3β-mediated nuclear translocation of Nrf2.
Human & experimental toxicology
Dong Z,Bian L,Wang YL,Sun LM
Wed Sep 01 00:00:00 EDT 2021
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Bioengineered
Zhao X,Wang J,Tang L,Li P,Ru J,Bai Y
Wed Dec 01 00:00:00 EST 2021
BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer's disease.
Cell death discovery
Zhang X,Li J,Ma L,Xu H,Cao Y,Liang W,Ma J,Wang ZP,Li Y
Mon Mar 15 00:00:00 EDT 2021
Tetramethylpyrazine inhibits neutrophil extracellular traps formation and alleviates hepatic ischemia/reperfusion injury in rat liver transplantation.
Experimental cell research
Liu Y,Qin X,Lei Z,Chai H,Huang Z,Wu Z
Wed Sep 01 00:00:00 EDT 2021
Chronic ethanol exposure induced depressive-like behavior in male C57BL/6 N mice by downregulating GluA1.
Physiology & behavior
Yao H,Shen H,Yu H,Wang C,Ding R,Lan X,Tash D,Wu X,Wang X,Zhang G
Sat May 15 00:00:00 EDT 2021
Knockdown of PYCR1 suppressed the malignant phenotype of human hepatocellular carcinoma cells via inhibiting the AKT pathway activation.
Reproductive biology
Guo J,Cheng X,Tian Y,Li B,Zhang X,Gao X,An Y
Wed Sep 01 00:00:00 EDT 2021
Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia-reperfusion injury.
Journal of advanced research
Lu S,Tian Y,Luo Y,Xu X,Ge W,Sun G,Sun X
Mon Mar 01 00:00:00 EST 2021
Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway.
Frontiers in pharmacology
Li J,Zhang Z,Wang L,Jiang L,Qin Z,Zhao Y,Su B
Tue Dec 28 00:00:00 EST 2021
Diosgenin From Dioscorea Nipponica Rhizoma Against Graves' Disease-On Network Pharmacology and Experimental Evaluation.
Frontiers in pharmacology
Xin J,Cheng W,Yu Y,Chen J,Zhang X,Shao S
Wed Feb 16 00:00:00 EST 2022
microRNA-9-5p alleviates blood-brain barrier damage and neuroinflammation after traumatic brain injury.
Journal of neurochemistry
Wu J,He J,Tian X,Luo Y,Zhong J,Zhang H,Li H,Cen B,Jiang T,Sun X
Mon Jun 01 00:00:00 EDT 2020
Maternal exposure to Di-(2-ethylhexyl) phthalate (DEHP) activates the PI3K/Akt/mTOR signaling pathway in F1 and F2 generation adult mouse testis.
Experimental cell research
Zhang J,Yao Y,Pan J,Guo X,Han X,Zhou J,Meng X
Tue Sep 15 00:00:00 EDT 2020
Simvastatin protects high glucose-induced H9c2 cells from injury by inducing autophagy.
Pharmaceutical biology
E L,Jiang H
Tue Dec 01 00:00:00 EST 2020
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Animals : an open access journal from MDPI
Xiong Y,Yin Q,Li J,He S
Thu Feb 27 00:00:00 EST 2020
Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters.
British journal of pharmacology
Huo X,Meng Q,Wang C,Wu J,Wang C,Zhu Y,Ma X,Sun H,Liu K
Fri May 01 00:00:00 EDT 2020
Amniotic Membrane Extract Protects Islets From Serum-Deprivation Induced Impairments and Improves Islet Transplantation Outcome.
Frontiers in endocrinology
Yang Z,Li X,Zhang C,Sun N,Guo T,Lin J,Li F,Zhang J
Thu May 27 00:00:00 EDT 2021
Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy.
Frontiers in pharmacology
Ye J,Lu S,Wang M,Ge W,Liu H,Qi Y,Fu J,Zhang Q,Zhang B,Sun G,Sun X
Mon May 10 00:00:00 EDT 2021
Integrin β3 promotes cardiomyocyte proliferation and attenuates hypoxia-induced apoptosis via regulating the PTEN/Akt/mTOR and ERK1/2 pathways.
International journal of biological sciences
Wei L,Zhou Q,Tian H,Su Y,Fu GH,Sun T
Thu Feb 04 00:00:00 EST 2021
Drp1-mediated mitochondrial fission induced autophagy attenuates cell apoptosis caused by 3-chlorpropane-1,2-diol in HEK293 cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Jin C,Zhong Y,Han J,Zhu J,Liu Q,Sun D,Xia X,Peng X
Sun Nov 01 00:00:00 EDT 2020
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
Oxidative medicine and cellular longevity
Kuang M,Yang M,Li L,Li C,Wang G
Wed May 05 00:00:00 EDT 2021
Let-7b downgrades CCND1 to repress osteogenic proliferation and differentiation of MC3T3-E1 cells: An implication in osteoporosis.
The Kaohsiung journal of medical sciences
Wang LJ,Cai HQ
Thu Oct 01 00:00:00 EDT 2020
Isorhamnetin Enhances the Radiosensitivity of A549 Cells Through Interleukin-13 and the NF-κB Signaling Pathway.
Frontiers in pharmacology
Du Y,Jia C,Liu Y,Li Y,Wang J,Sun K
Fri Feb 12 00:00:00 EST 2021
Long Noncoding RNA TCONS_00016406 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Regulating the miR-687/PTEN Pathway.
Frontiers in physiology
Liu X,Zhu N,Zhang B,Xu SB
Mon Sep 28 00:00:00 EDT 2020
Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease.
Cell death & disease
Zhang W,Gong J,Ding L,Zhang Z,Pan X,Chen X,Guo W,Zhang X,Yang X,Peng G,Lin Y,Gao F,Li Y,Zhu X,Xuan A,Wang S,Sun X,Zhang Y,Xu P
Thu Oct 22 00:00:00 EDT 2020
The Protective Effect of Luteolin in Glucocorticoid-Induced Osteonecrosis of the Femoral Head.
Frontiers in pharmacology
Yan Z,Zhan J,Qi W,Lin J,Huang Y,Xue X,Pan X
Mon Sep 28 00:00:00 EDT 2020
Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice.
Aging and disease
Sun Y,Lu F,Yu X,Wang B,Chen J,Lu F,Peng S,Sun X,Yu M,Chen H,Wang Y,Zhang L,Liu N,Du H,Zhao D,Zhang W
Wed Apr 01 00:00:00 EDT 2020
Inhibition of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 attenuates high glucose-induced cardiomyocyte apoptosis via regulation of miR-181a-5p.
Experimental animals
Cheng Y,Li J,Wang C,Yang H,Wang Y,Zhan T,Guo S,Liang J,Bai Y,Yu J,Liu G
Wed Jan 29 00:00:00 EST 2020
ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.
Archives of biochemistry and biophysics
Xu A,Shang W,Wang Y,Sun X,Zhou B,Xie Y,Xu X,Liu T,Han F
Thu Jul 30 00:00:00 EDT 2020
High mobility group box 1 antibody represses autophagy and alleviates hippocampus damage in pilocarpine-induced mouse epilepsy model.
Acta histochemica
Ying C,Ying L,Yanxia L,Le W,Lili C
Sat Feb 01 00:00:00 EST 2020
Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis.
Naunyn-Schmiedeberg's archives of pharmacology
Jin W,Zhang Y,Xue Y,Han X,Zhang X,Ma Z,Sun S,Chu X,Cheng J,Guan S,Li Z,Chu L
Wed Jan 01 00:00:00 EST 2020
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Oxidative medicine and cellular longevity
Wang W,Hu X,Xia Z,Liu Z,Zhong Z,Lu Z,Liu A,Ye S,Cao Q,Wang Y,Zhu F,Ye Q
Wed Dec 16 00:00:00 EST 2020
Metformin Inhibits Propofol-Induced Apoptosis of Mouse Hippocampal Neurons HT-22 Through Downregulating Cav-1.
Drug design, development and therapy
Ge J,Huang Y,Zhang Y,Liu L,Gu T,Liu X,Yao L,Cai M,Sun J,Song J
Wed Mar 10 00:00:00 EST 2021
Tannic acid ameliorates arsenic trioxide-induced nephrotoxicity, contribution of NF-κB and Nrf2 pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jin W,Xue Y,Xue Y,Han X,Song Q,Zhang J,Li Z,Cheng J,Guan S,Sun S,Chu L
Mon Jun 01 00:00:00 EDT 2020
Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity.
Journal of natural medicines
Li Y,Chen H,Yang Y,Niu M,Wang J,Wu Y,Niu L,Liu H,Bao D
Sun Mar 01 00:00:00 EST 2020
The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice.
Behavioural brain research
Liu Q,Zhang S,Zhu D,Tang X,Che Y,Feng X
Mon Feb 03 00:00:00 EST 2020
Overexpression of miR-150-5p Alleviates Apoptosis in Sepsis-Induced Myocardial Depression.
BioMed research international
Zhu XG,Zhang TN,Wen R,Liu CF
Wed Apr 28 00:00:00 EDT 2021
Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways.
Journal of hazardous materials
Liu H,Zhang W,Fang Y,Yang H,Tian L,Li K,Lai W,Bian L,Lin B,Liu X,Xi Z
Mon Jun 15 00:00:00 EDT 2020
Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy.
Life sciences
Yuan M,Yang X,Duscher D,Xiong H,Ren S,Xu X,Wang C,Chen J,Liu Y,Machens HG,Chen Z
Tue Sep 01 00:00:00 EDT 2020
Involvement of ROS/NLRP3 Inflammasome Signaling Pathway in Doxorubicin-Induced Cardiotoxicity.
Cardiovascular toxicology
Wei S,Ma W,Li X,Jiang C,Sun T,Li Y,Zhang B,Li W
Thu Oct 01 00:00:00 EDT 2020
NOD2/c-Jun NH2-Terminal Kinase Triggers Mycoplasma ovipneumoniae-Induced Macrophage Autophagy.
Journal of bacteriology
Luo H,Wu X,Xu Z,Hao X,Wang Y,Li M
Wed Sep 23 00:00:00 EDT 2020
Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis.
Scientific reports
Shi B,Huang Y,Ni J,Chen J,Wei J,Gao H,Li L,Zhou Z,Wang Y,Xu Y,Xu Z,Mao J,Fan G
Wed Apr 08 00:00:00 EDT 2020
Inhibition of Brd4 by JQ1 Promotes Functional Recovery From Spinal Cord Injury by Activating Autophagy.
Frontiers in cellular neuroscience
Li Y,Xiang J,Zhang J,Lin J,Wu Y,Wang X
Thu Oct 01 00:00:00 EDT 2020
Baicalein suppresses the proliferation and invasiveness of colorectal cancer cells by inhibiting Snail‑induced epithelial‑mesenchymal transition.
Molecular medicine reports
Zeng Q,Zhang Y,Zhang W,Guo Q
Mon Jun 01 00:00:00 EDT 2020
Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis.
Mediators of inflammation
Deng Y,Yang L,Xie Q,Yang F,Li G,Zhang G,Li S,Wu Z,Wang J,Kang X
Mon Feb 01 00:00:00 EST 2021
Epigenetic Upregulation of Chicken MicroRNA-16-5p Expression in DF-1 Cells following Infection with Infectious Bursal Disease Virus (IBDV) Enhances IBDV-Induced Apoptosis and Viral Replication.
Journal of virology
Duan X,Zhao M,Wang Y,Li X,Cao H,Zheng SJ
Mon Jan 06 00:00:00 EST 2020
A small-molecule ARTS mimetic promotes apoptosis through degradation of both XIAP and Bcl-2.
Cell death & disease
Mamriev D,Abbas R,Klingler FM,Kagan J,Kfir N,Donald A,Weidenfeld K,Sheppard DW,Barkan D,Larisch S
Thu Jun 25 00:00:00 EDT 2020
Liraglutide regulates proliferation, differentiation, and apoptosis of preosteoblasts through a signaling network of Notch/Wnt/Hedgehog signaling pathways.
European review for medical and pharmacological sciences
Hou HW,Xue P,Wang Y,Li YK
Tue Dec 01 00:00:00 EST 2020
MiR-128-3p Alleviates Spinal Cord Ischemia/Reperfusion Injury Associated Neuroinflammation and Cellular Apoptosis via SP1 Suppression in Rat.
Frontiers in neuroscience
Wang D,Chen F,Fang B,Zhang Z,Dong Y,Tong X,Ma H
Fri Nov 10 00:00:00 EST 2023
Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.
Bioscience, biotechnology, and biochemistry
Guo X,Zhang Y,Lu C,Qu F,Jiang X
Wed Apr 01 00:00:00 EDT 2020
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
The journal of gene medicine
Chen GH,Zhang XL,Chen H,Lin H,Wu HJ,Lin H,Huang GZ
Mon Jun 01 00:00:00 EDT 2020
The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats.
Biological trace element research
Liu Y,Chen H,Zhang L,Zhang T,Ren X
Fri May 01 00:00:00 EDT 2020
Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1.
Neuroscience
Wu J,He J,Tian X,Li H,Wen Y,Shao Q,Cheng C,Wang G,Sun X
Sat Aug 01 00:00:00 EDT 2020
Protective effects of alfalfa saponins on oxidative stress-induced apoptotic cells.
Food & function
Cui Y,Liu B,Sun X,Li Z,Chen Y,Guo Z,Liu H,Li D,Wang C,Zhu X,Shi Y
Wed Sep 23 00:00:00 EDT 2020
MiR-489 aggravates H2O2-induced apoptosis of cardiomyocytes via inhibiting IGF1.
Bioscience reports
Tang S,Zhong H,Xiong T,Yang X,Mao Y,Wang D
Wed Sep 30 00:00:00 EDT 2020
Combination of Dichloroacetate and Atorvastatin Regulates Excessive Proliferation and Oxidative Stress in Pulmonary Arterial Hypertension Development via p38 Signaling.
Oxidative medicine and cellular longevity
Li T,Li S,Feng Y,Zeng X,Dong S,Li J,Zha L,Luo H,Zhao L,Liu B,Ou Z,Lin W,Zhang M,Li S,Jiang Q,Qi Q,Xu Q,Yu Z
Fri Feb 05 00:00:00 EST 2021
4-hydroxy-2(3H)-benzoxazolone alleviates acetaminophen-induced hepatic injury by inhibiting NF-κB and activating Nrf2/HO-1 signaling pathways.
American journal of translational research
Wei X,Wang H,Sun X,Huang X,Xu W,Liang Y,Liu L,Mo S,Lin X,Lin J
Mon Sep 28 00:00:00 EDT 2020
Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2.
Journal of animal physiology and animal nutrition
Xu B,Zang SC,Lang LM,Lian S,Lu J,Li SZ,Yang HM,Zhen L
Sun Nov 01 00:00:00 EDT 2020
MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis.
ACS chemical neuroscience
Ma S,Wang Y,Zhou X,Li Z,Zhang Z,Wang Y,Huang T,Zhang Y,Shi J,Guan F
Wed Sep 02 00:00:00 EDT 2020
Ameliorative effects and mechanism of crocetin in arsenic trioxide‑induced cardiotoxicity in rats.
Molecular medicine reports
Zhao Z,Li J,Zheng B,Liang Y,Shi J,Zhang J,Han X,Chu L,Chu X,Gao Y
Tue Dec 01 00:00:00 EST 2020
Bungeanum Improves Cognitive Dysfunction and Neurological Deficits in D-Galactose-Induced Aging Mice via Activating PI3K/Akt/Nrf2 Signaling Pathway.
Frontiers in pharmacology
Zhao M,Tang X,Gong D,Xia P,Wang F,Xu S
Mon Sep 28 00:00:00 EDT 2020
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Yu J,Ma C,Xu Y,Han L,Wu X,Wang Y,Deng G
Sun Nov 01 00:00:00 EDT 2020
Autophagy plays a protective role during Pseudomonas aeruginosa-induced apoptosis via ROS-MAPK pathway.
Innate immunity
Han L,Ma Q,Yu J,Gong Z,Ma C,Xu Y,Deng G,Wu X
Thu Oct 01 00:00:00 EDT 2020
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Drug design, development and therapy
Kong J,Wang J,Gong X,Zheng X,Chen T
Tue Sep 21 00:00:00 EDT 2021
Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway.
Oxidative medicine and cellular longevity
Luan Y,Cui K,Tang Z,Ruan Y,Liu K,Wang T,Chen Z,Wang S,Liu J
Tue Nov 10 00:00:00 EST 2020
An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid.
Frontiers in pharmacology
Ma C,Wang X,Xu T,Zhang S,Liu S,Zhai C,Wang Z,Mu J,Li C,Cheng F,Wang Q
Mon Sep 28 00:00:00 EDT 2020
LncRNA MALAT1 inhibits apoptosis of endometrial stromal cells through miR-126-5p-CREB1 axis by activating PI3K-AKT pathway.
Molecular and cellular biochemistry
Feng Y,Tan BZ
Tue Dec 01 00:00:00 EST 2020
Effect of autophagy on irradiation‑induced damage in osteoblast‑like MC3T3‑E1 cells.
Molecular medicine reports
Li R,Yang W,Hu X,Zhou D,Huang K,Wang C,Li Y,Liu B
Thu Oct 01 00:00:00 EDT 2020
Hydrogen Gas Attenuates Hypoxic-Ischemic Brain Injury via Regulation of the MAPK/HO-1/PGC-1a Pathway in Neonatal Rats.
Oxidative medicine and cellular longevity
Wang P,Zhao M,Chen Z,Wu G,Fujino M,Zhang C,Zhou W,Zhao M,Hirano SI,Li XK,Zhao L
Fri Nov 06 00:00:00 EST 2020
Overexpression of Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α Protects Cardiomyocytes from Lipopolysaccharide-Induced Mitochondrial Damage and Apoptosis.
Inflammation
Zhang T,Liu CF,Zhang TN,Wen R,Song WL
Thu Oct 01 00:00:00 EDT 2020
Overexpression of Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α Protects Cardiomyocytes from Lipopolysaccharide-Induced Mitochondrial Damage and Apoptosis.
Inflammation
Zhang T,Liu CF,Zhang TN,Wen R,Song WL
Thu Oct 01 00:00:00 EDT 2020
Mechanisms underlying the protective effect of tannic acid against arsenic trioxide‑induced cardiotoxicity in rats: Potential involvement of mitochondrial apoptosis.
Molecular medicine reports
Xue Y,Li M,Xue Y,Jin W,Han X,Zhang J,Chu X,Li Z,Chu L
Tue Dec 01 00:00:00 EST 2020
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
Aging
Cui Y,Song Y,Yan S,Cao M,Huang J,Jia D,Liu Y,Zhang S,Fan W,Cai L,Li C,Xing Y
Sun Oct 25 00:00:00 EDT 2020
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
Aging
Cui Y,Song Y,Yan S,Cao M,Huang J,Jia D,Liu Y,Zhang S,Fan W,Cai L,Li C,Xing Y
Sun Oct 25 00:00:00 EDT 2020
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
Fitoterapia
Shi YS,Xia HM,Wu CH,Li CB,Duan CC,Che C,Zhang XJ,Li HT,Zhang Y,Zhang XF
Wed Apr 01 00:00:00 EDT 2020
Selenium ameliorates cadmium-induced mouse leydig TM3 cell apoptosis via inhibiting the ROS/JNK /c-jun signaling pathway.
Ecotoxicology and environmental safety
Ren X,Wang S,Zhang C,Hu X,Zhou L,Li Y,Xu L
Wed Apr 01 00:00:00 EDT 2020
Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway.
Oxidative medicine and cellular longevity
Cui G,Li L,Xu W,Wang M,Jiao D,Yao B,Xu K,Chen Y,Yang S,Long M,Li P,Guo Y
Tue Nov 10 00:00:00 EST 2020
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Life sciences
Luo J,Yang C,Luo X,Yang Y,Li J,Song B,Zhao J,Li L
Sat Aug 01 00:00:00 EDT 2020
Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis.
Life sciences
Luo J,Yang C,Luo X,Yang Y,Li J,Song B,Zhao J,Li L
Sat Aug 01 00:00:00 EDT 2020
Shenmai Injection Supresses Glycolysis and Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant A549/DDP Cells via the AKT-mTOR-c-Myc Signaling Pathway.
BioMed research international
Sun Y,Chen Y,Xu M,Liu C,Shang H,Wang C
Wed Apr 14 00:00:00 EDT 2021
Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson's Disease.
Molecules (Basel, Switzerland)
Wu T,Fang X,Xu J,Jiang Y,Cao F,Zhao L
Mon Aug 31 00:00:00 EDT 2020
Salvianolic Acid B Protects Against Fatty Acid-Induced Renal Tubular Injury via Inhibition of Endoplasmic Reticulum Stress.
Frontiers in pharmacology
Mai X,Yin X,Chen P,Zhang M
Sat Jan 02 00:00:00 EST 2021
The testis-specifically expressed gene Trim69 is not essential for fertility in mice.
Journal of biomedical research
He X,Xie W,Li H,Cui Y,Wang Y,Guo X,Sha J
Fri Aug 21 00:00:00 EDT 2020
Morroniside Inhibits H2O2-Induced Podocyte Apoptosis by Down-Regulating NOX4 Expression Controlled by Autophagy In Vitro.
Frontiers in pharmacology
Gao X,Liu Y,Wang L,Sai N,Liu Y,Ni J
Thu Oct 22 00:00:00 EDT 2020
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway.
International journal of clinical and experimental pathology
Li L,Peng X,Guo L,Zhao Y,Cheng Q
Thu Jun 11 00:00:00 EDT 2020
Sodium tanshinone IIA sulfonate prevents radiation-induced damage in primary rat cardiac fibroblasts.
Chinese journal of natural medicines
Zhou D,Yang WK,Zhang YF,Xie JH,Ma L,Yang HD,Li Y,Xie P
Mon Jun 01 00:00:00 EDT 2020
Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inflammation, and Oxidative Stress.
Frontiers in pharmacology
Wang H,Xia W,Long G,Pei Z,Li Y,Wu M,Wang Q,Zhang Y,Jia Z,Chen H
Tue Jan 12 00:00:00 EST 2021
Protective Effect of Astaxanthin on Blue Light Light-Emitting Diode-Induced Retinal Cell Damage via Free Radical Scavenging and Activation of PI3K/Akt/Nrf2 Pathway in 661W Cell Model.
Marine drugs
Lin CW,Yang CM,Yang CH
Sat Jul 25 00:00:00 EDT 2020
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
FEBS open bio
Chen M,Li S,Hao M,Chen J,Zhao Z,Hong S,Min J,Tang J,Hu M,Hong L
Thu Oct 01 00:00:00 EDT 2020
The role of STAT3/p53 and PI3K-Akt-mTOR signaling pathway on DEHP-induced reproductive toxicity in pubertal male rat.
Toxicology and applied pharmacology
Fu G,Dai J,Li Z,Chen F,Liu L,Yi L,Teng Z,Quan C,Zhang L,Zhou T,Donkersley P,Song S,Shi Y
Thu Oct 01 00:00:00 EDT 2020
The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis.
OncoTargets and therapy
Shang Y,Wang Q,Li J,Zhao Q,Huang X,Dong H,Liu H,Zhang Y,Zhang J,Gui R,Nie X
Tue Apr 12 00:00:00 EDT 2022
The protective role of microRNA-133b in restricting hippocampal neurons apoptosis and inflammatory injury in rats with depression by suppressing CTGF.
International immunopharmacology
Pei G,Xu L,Huang W,Yin J
Wed Jan 01 00:00:00 EST 2020
Bishonokiol A Induces Multiple Cell Death in Human Breast Cancer MCF-7 Cells.
Asian Pacific journal of cancer prevention : APJCP
Li HM,Li B,Ma H,Sun X,Zhu M,Dai Y,Ma T,Huo Q,Wu CZ
Wed Apr 01 00:00:00 EDT 2020
Long Noncoding RNA LNC_000898 Alleviates Cardiomyocyte Apoptosis and Promotes Cardiac Repair After Myocardial Infarction Through Modulating the miR-375/PDK1 Axis.
Journal of cardiovascular pharmacology
Yan M,Liu Q,Jiang Y,Wang B,Ji Y,Liu H,Xie Y
Wed Jul 01 00:00:00 EDT 2020
Astaxanthin suppresses lipopolysaccharide‑induced myocardial injury by regulating MAPK and PI3K/AKT/mTOR/GSK3β signaling.
Molecular medicine reports
Xie WJ,Hou G,Wang L,Wang SS,Xiong XX
Thu Oct 01 00:00:00 EDT 2020
Antianemia Drug Roxadustat (FG-4592) Protects Against Doxorubicin-Induced Cardiotoxicity by Targeting Antiapoptotic and Antioxidative Pathways.
Frontiers in pharmacology
Long G,Chen H,Wu M,Li Y,Gao L,Huang S,Zhang Y,Jia Z,Xia W
Mon Sep 28 00:00:00 EDT 2020
A Combination of BRD4 and HDAC3 Inhibitors Synergistically Suppresses Glioma Stem Cell Growth by Blocking GLI1/IL6/STAT3 Signaling Axis.
Molecular cancer therapeutics
Wang Q,Jia S,Wang D,Chen X,Kalvakolanu DV,Zheng H,Wei X,Wen N,Liang H,Guo B,Zhang L
Tue Dec 01 00:00:00 EST 2020
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Planta medica
Han B,Jiang L,Jiang P,Zhou D,Jia X,Li X,Ye X
Wed Jul 01 00:00:00 EDT 2020
Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway.
Planta medica
Han B,Jiang L,Jiang P,Zhou D,Jia X,Li X,Ye X
Wed Jul 01 00:00:00 EDT 2020
Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway.
Life sciences
Shopit A,Niu M,Wang H,Tang Z,Li X,Tesfaldet T,Ai J,Ahmad N,Al-Azab M,Tang Z
Sat Feb 01 00:00:00 EST 2020
Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis.
Molecular medicine (Cambridge, Mass.)
Wang W,Zheng L,Xu L,Tu J,Gu X
Wed May 27 00:00:00 EDT 2020
TIPE2 ameliorates lipopolysaccharide-induced apoptosis and inflammation in acute lung injury.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Wu X,Kong Q,Zhan L,Qiu Z,Huang Q,Song X
Fri Nov 01 00:00:00 EDT 2019
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Inflammation
Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Liu X,Sun H
Fri Feb 01 00:00:00 EST 2019
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Inflammation
Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu Z,Liu K,Liu X,Sun H
Fri Feb 01 00:00:00 EST 2019
The protective role of microRNA-140-5p in synovial injury of rats with knee osteoarthritis via inactivating the TLR4/Myd88/NF-κB signaling pathway.
Cell cycle (Georgetown, Tex.)
Huang X,Qiao F,Xue P
Sun Sep 01 00:00:00 EDT 2019
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy.
Food & function
Chen C,Jiang L,Zhang M,Pan X,Peng C,Huang W,Jiang Q
Wed May 22 00:00:00 EDT 2019
Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma.
Current medical science
Guo J,Fu W,Xiang M,Zhang Y,Zhou K,Xu CR,Li L,Kuang D,Ye F
Sun Dec 01 00:00:00 EST 2019
Citreoviridin induces myocardial apoptosis through PPAR-γ-mTORC2-mediated autophagic pathway and the protective effect of thiamine and selenium.
Chemico-biological interactions
Feng C,Li D,Chen M,Jiang L,Liu X,Li Q,Geng C,Sun X,Yang G,Zhang L,Yao X
Wed Sep 25 00:00:00 EDT 2019
Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1.
Cell cycle (Georgetown, Tex.)
Feng X,Xiong W,Yuan M,Zhan J,Zhu X,Wei Z,Chen X,Cheng X
Fri Nov 01 00:00:00 EDT 2019
HBOA ameliorates CCl4-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Sun X,Huang X,Zhu X,Liu L,Mo S,Wang H,Wei X,Lu S,Bai F,Wang D,Lin X,Lin J
Mon Jul 01 00:00:00 EDT 2019
Inhibition of cyclin-dependent kinase 5 activity alleviates diabetes-related cognitive deficits.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu W,Zhou Y,Liang R,Zhang Y
Sun Dec 01 00:00:00 EST 2019
Effect of astaxanthin on apoptosis of rat renal tubular epithelial cells induced by iohexol.
American journal of translational research
Xu Y,Yao S,Gao D,Li W,Zheng D,Zhang Q
Tue Sep 29 00:00:00 EDT 2020
Protective effects of Panax notoginseng saponins on PME-Induced nephrotoxicity in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Y,Chi X,Wang Z,Bi S,Wang Y,Shi F,Hu S,Wang H
Thu Aug 01 00:00:00 EDT 2019
Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids.
Apoptosis : an international journal on programmed cell death
Ma H,Yu Y,Wang M,Li Z,Xu H,Tian C,Zhang J,Ye X,Li X
Fri Feb 01 00:00:00 EST 2019
Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy.
Experimental & molecular medicine
Xu WN,Zheng HL,Yang RZ,Liu T,Yu W,Zheng XF,Li B,Jiang SD,Jiang LS
Mon Nov 18 00:00:00 EST 2019
ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway.
Molecular and cellular biochemistry
Liu R,Xu X,Liang C,Chen X,Yu X,Zhong H,Xu W,Cheng Y,Wang W,Wu Y,Yu L,Hu X
Sat Jun 01 00:00:00 EDT 2019
Milk fat globule-epidermal growth factor 8 (MFG-E8) attenuates sepsis-induced acute kidney injury by inhibiting NF-κB signaling pathway1.
Acta cirurgica brasileira
Zhao Y,Wang Q,Zang B
Thu Feb 28 00:00:00 EST 2019
Treatment with metformin prevents myocardial ischemia-reperfusion injury via STEAP4 signaling pathway.
Anatolian journal of cardiology
Luo T,Zeng X,Yang W,Zhang Y
Mon Apr 01 00:00:00 EDT 2019
Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro.
Oxidative medicine and cellular longevity
Du Y,Qian B,Gao L,Tan P,Chen H,Wang A,Zheng T,Pu S,Xia X,Fu W
Mon Apr 27 00:00:00 EDT 2020
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal.
Frontiers in pharmacology
Song S,Chu L,Liang H,Chen J,Liang J,Huang Z,Zhang B,Chen X
Thu Oct 01 00:00:00 EDT 2020
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
International journal of medical sciences
Wang Q,Jia S,Jiao Y,Xu L,Wang D,Chen X,Hu X,Liang H,Wen N,Zhang S,Guo B,Zhang L
Thu Apr 30 00:00:00 EDT 2020
SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway.
International journal of medical sciences
Wang Q,Jia S,Jiao Y,Xu L,Wang D,Chen X,Hu X,Liang H,Wen N,Zhang S,Guo B,Zhang L
Thu Apr 30 00:00:00 EDT 2020
Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells.
Pain physician
Zhang L,Liu Y,Huang Z,Nan L,Wang F,Zhou S,Wang J,Feng X
Fri Mar 01 00:00:00 EST 2019
Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice.
Acta pharmacologica Sinica
Huang ZB,Zheng YX,Li N,Cai SL,Huang Y,Wang J,Hu XW,Wang Y,Wu J,Fan XG
Fri Nov 01 00:00:00 EDT 2019
Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms.
Evidence-based complementary and alternative medicine : eCAM
Wang Y,Wu JZ,Li Y,Qi X
Sat Apr 09 00:00:00 EDT 2022
Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis.
Reproductive biology and endocrinology : RB&E
Yang Q,Zhu J,Luo X,Li F,Cong L,Wang Y,Sun Y
Mon Jul 29 00:00:00 EDT 2019
PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy.
International journal of biological macromolecules
Xu WN,Yang RZ,Zheng HL,Yu W,Zheng XF,Li B,Jiang SD,Jiang LS
Sun Sep 01 00:00:00 EDT 2019
TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat.
Biochemical and biophysical research communications
Zhang J,Yao D,Zhang J,Song Y,Mo F,Chu X,Pan Y,Bai Y,Shao C
Sun Jun 30 00:00:00 EDT 2019
MicroRNA-129-5p alleviates nerve injury and inflammatory response of Alzheimer's disease via downregulating SOX6.
Cell cycle (Georgetown, Tex.)
Zeng Z,Liu Y,Zheng W,Liu L,Yin H,Zhang S,Bai H,Hua L,Wang S,Wang Z,Li X,Xiao J,Yuan Q,Wang Y
Fri Nov 01 00:00:00 EDT 2019
The protective effects of salvianolic acid A against hepatic ischemia-reperfusion injury via inhibiting expression of toll-like receptor 4 in rats.
Archives of medical science : AMS
Yang L,Jiang L,Jiang D,Liu B,Jin S
Tue Oct 01 00:00:00 EDT 2019
In vivo tracking on longer retention of transplanted myocardin gene-modified adipose-derived stem cells to improve erectile dysfunction in diabetic rats.
Stem cell research & therapy
Zhang HB,Chen FZ,He SH,Liang YB,Wang ZQ,Wang L,Chen ZR,Ding W,Zhao SC,Wei AY
Tue Jul 16 00:00:00 EDT 2019
H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling.
Aging
Zhang Y,Gao J,Sun W,Wen X,Xi Y,Wang Y,Wei C,Xu C,Li H
Tue Mar 26 00:00:00 EDT 2019
Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway.
Ecotoxicology and environmental safety
Yin F,Yan J,Zhao Y,Guo KJ,Zhang ZL,Li AP,Meng CY,Guo L
Tue Jul 30 00:00:00 EDT 2019
Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
He F,Dai R,Zhou X,Li X,Song X,Yan H,Meng Q,Yang C,Lin Q
Tue Oct 01 00:00:00 EDT 2019
Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration.
Life sciences
Dong S,Ji J,Hu L,Wang H
Sat Jun 15 00:00:00 EDT 2019
MicroRNA‑1 downregulation induced by carvedilol protects cardiomyocytes against apoptosis by targeting heat shock protein 60.
Molecular medicine reports
Hu Y,Chen X,Li X,Li Z,Diao H,Liu L,Zhang J,Ju J,Wen L,Liu X,Pan Z,Xu C,Hai X,Zhang Y
Wed May 01 00:00:00 EDT 2019
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Cornea
Zhao W,Che C,Liu K,Zhang J,Jiang N,Yuan K,Zhao G
Sat Dec 01 00:00:00 EST 2018
Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis.
Cornea
Zhao W,Che C,Liu K,Zhang J,Jiang N,Yuan K,Zhao G
Sat Dec 01 00:00:00 EST 2018
Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury.
CNS neuroscience & therapeutics
Duan HQ,Wu QL,Yao X,Fan BY,Shi HY,Zhao CX,Zhang Y,Li B,Sun C,Kong XH,Zhou XF,Feng SQ
Tue May 01 00:00:00 EDT 2018
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Medical science monitor : international medical journal of experimental and clinical research
Zhang Y,Yang B,Zhao J,Li X,Zhang L,Zhai Z
Mon Jan 15 00:00:00 EST 2018
Proteasome Inhibitor Carbobenzoxy-L-Leucyl-L-Leucyl-L-Leucinal (MG132) Enhances Therapeutic Effect of Paclitaxel on Breast Cancer by Inhibiting Nuclear Factor (NF)-κB Signaling.
Medical science monitor : international medical journal of experimental and clinical research
Zhang Y,Yang B,Zhao J,Li X,Zhang L,Zhai Z
Mon Jan 15 00:00:00 EST 2018
Atrazine exposure improves the proliferation of H22 cells in vitro and in vivo.
RSC advances
Tian Y,He J,Liu N,Huang D,Liu Z,Yang Y,Chen J,Zhao B,Zhao S,Liang B
Wed Jun 13 00:00:00 EDT 2018
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
RSC advances
Pei Z,Hu J,Bai Q,Liu B,Cheng D,Liu H,Na R,Yu Q
Tue Apr 17 00:00:00 EDT 2018
Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1.
Chinese medical journal
Zhao YX,Zhang HR,Yang XN,Zhang YH,Feng S,Yu FX,Yan XX
Sat Oct 20 00:00:00 EDT 2018
Fine Particulate Matter-Induced Exacerbation of Allergic Asthma via Activation of T-cell Immunoglobulin and Mucin Domain 1.
Chinese medical journal
Zhao YX,Zhang HR,Yang XN,Zhang YH,Feng S,Yu FX,Yan XX
Sat Oct 20 00:00:00 EDT 2018
L-PGDS Mediates Vagus Nerve Stimulation-Induced Neuroprotection in a Rat Model of Ischemic Stroke by Suppressing the Apoptotic Response.
Neurochemical research
Zhang L,Ma J,Jin X,Jia G,Jiang Y,Li C
Wed Feb 01 00:00:00 EST 2017
Acid sphingomyelinase/ceramide regulates carotid intima-media thickness in simulated weightless rats.
Pflugers Archiv : European journal of physiology
Cheng YP,Zhang HJ,Su YT,Meng XX,Xie XP,Chang YM,Bao JX
Thu Jun 01 00:00:00 EDT 2017
MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS.
African journal of traditional, complementary, and alternative medicines : AJTCAM
Chen Y,Li Y,Xu H,Li G,Ma Y,Pang YJ
Wed Aug 16 00:00:00 EDT 2017
Hepatoprotective effect of quercetin against LPS/d-GalN induced acute liver injury in mice by inhibiting the IKK/NF-κB and MAPK signal pathways.
International immunopharmacology
Peng Z,Gong X,Yang Y,Huang L,Zhang Q,Zhang P,Wan R,Zhang B
Wed Nov 01 00:00:00 EDT 2017
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu L,Wang C,Li J,Li S,Feng J,Liu T,Xu S,Wang W,Lu X,Chen K,Xia Y,Fan X,Guo C
Fri Dec 01 00:00:00 EST 2017
Hepatoprotective effect of quercetin via TRAF6/JNK pathway in acute hepatitis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu L,Wang C,Li J,Li S,Feng J,Liu T,Xu S,Wang W,Lu X,Chen K,Xia Y,Fan X,Guo C
Fri Dec 01 00:00:00 EST 2017
Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPARγ/NLRP3 inflammasome signaling pathway.
Oncotarget
Xu Y,Yao J,Zou C,Zhang H,Zhang S,Liu J,Ma G,Jiang P,Zhang W
Tue Oct 17 00:00:00 EDT 2017
Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPARγ/NLRP3 inflammasome signaling pathway.
Oncotarget
Xu Y,Yao J,Zou C,Zhang H,Zhang S,Liu J,Ma G,Jiang P,Zhang W
Tue Oct 17 00:00:00 EDT 2017
Protective effects of aloperin on monocroline-induced pulmonary hypertension via regulation of Rho A/Rho kinsase pathway in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wu F,Yao W,Yang J,Zhang M,Xu Y,Hao Y,Yan L,Niu Y,Sun T,Yu J,Zhou R
Wed Nov 01 00:00:00 EDT 2017
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology
Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X
Mon Feb 15 00:00:00 EST 2016
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology
Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X
Mon Feb 15 00:00:00 EST 2016
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology
Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X
Mon Feb 15 00:00:00 EST 2016
KLF5 mediates vascular remodeling via HIF-1α in hypoxic pulmonary hypertension.
American journal of physiology. Lung cellular and molecular physiology
Li X,He Y,Xu Y,Huang X,Liu J,Xie M,Liu X
Mon Feb 15 00:00:00 EST 2016
Inhibitory effect of diosgenin on experimentally induced benign prostatic hyperplasia in rats.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban
Chen J,Zhang HF,Xiong CM,Ruan JL
Thu Dec 01 00:00:00 EST 2016
H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.
Oncotarget
Zhao S,Li L,Wang S,Yu C,Xiao B,Lin L,Cong W,Cheng J,Yang W,Sun W,Cui S
Tue Dec 20 00:00:00 EST 2016
Effects of the total saponins from Rosa laevigata Michx fruit against acetaminophen-induced liver damage in mice via induction of autophagy and suppression of inflammation and apoptosis.
Molecules (Basel, Switzerland)
Dong D,Xu L,Han X,Qi Y,Xu Y,Yin L,Liu K,Peng J
Fri May 30 00:00:00 EDT 2014
The roles of autophagy and apoptosis in burn wound progression in rats.
Burns : journal of the International Society for Burn Injuries
Tan JQ,Zhang HH,Lei ZJ,Ren P,Deng C,Li XY,Chen SZ
Sun Dec 01 00:00:00 EST 2013