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Bethyl Laboratories
This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.
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Protein Aliases: a-LACTA; alfaLA; alpha lactabumin; alpha lactalbumin; Alpha-lactalbumin; alpha-lactalbumin A; alpha-lactalbumin B; alpha-lactalbumin precursor (EC 2.4.1.22); alpha-lactalbumin precursor protein; alpha-lactalbumin protein variant D; lactalbumin; Lactose synthase B protein; MGC138521; MGC138523
Gene Aliases: a-LACTA; ALACTA; alfaLA; LALBA
UniProt ID: (Bovine) P00711
Entrez Gene ID: (Bovine) 281894
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