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Invitrogen
Butyrylcholinesterase Monoclonal Antibody (3E8)
Product Details
HAH 002-01-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Rhesus monkey
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3E8
Immunogen
Butyrylcholinesterase isolated from human plasma.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.05% sodium azide
Storage conditions
-20° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2063729
Product Specific Information
HAH 002-01-02 has specificity for butyrylcholinesterase from human serum or plasma. Crossreactivity to BtChE from other species has not been tested.
HAH 002-01-02 has been successfully used in ELISA techniques.
HAH 002-01-02 reacts with BtChE from normal serum when tested in sandwich ELISA. This antibody can be used as both the capture and detection antibody or an alternative antibody against BtChE can be used as capture antibody. In addition, it can be used in crossed immunoelectrophoresis followed by incubation of the gel with HAH 002-01-02. In immunoblotting after SDS-PAGE no reaction is seen with either the reduced or with the non-reduced form of BtChE. No reaction is seen with acetylcholinesterase from human nervous tissue and erythrocytes.
The HAH 002-01-02 immunogen is Butyrylcholinesterase found in human plasma cells.
Target Information
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Acylcholine acylhydrolase; BtChE; Butyrylcholine esterase; Choline esterase II; Cholinesterase; cholinesterase (serum) 2; cholinesterase 1; EC 3.1.1.8; Pseudocholinesterase
Gene Aliases: BCHE; CHE1; CHE2; E1
UniProt ID: (Human) P06276
Entrez Gene ID: (Human) 590
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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