Invitrogen

C/EBP beta Monoclonal Antibody (18F8)

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Product Details

MA1-826

Applications
Tested Dilution
Publications

Western Blot (WB)

2 µg/mL
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

Immunoprecipitation (IP)

Assay-dependent
-

Miscellaneous PubMed (Misc)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Not Applicable

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

18F8

Immunogen

Synthetic peptide corresponding to residues M(1) H R L L A W D A A C L P P P A A F P K L H(21) of mouse C/EBP beta.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2276066

Product Specific Information

MA1-826 detects C/EBP beta protein in human, mouse, and rat samples. MA1-826 only detects the LAP* isoform of C/EBP beta.

MA1-826 has successfully been used in Western blot, immunofluorescent and immunoprecipitation procedures. By Western blot, this antibody detects a 37 kDa protein representing LAP* of C/EBP beta (N-terminus fragment) in transfected 293T cells.

The MA1-826 immunogen is a synthetic peptide corresponding to residues M(1) H R L L A W D A A C L P P P A A F P K L H(21) of mouse C/EBP beta. This peptide (Cat. # PEP-243) is available for use in neutralization and control experiments.

Target Information

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: AGP/EBP; C EBP; C/EBP BETA; C/EBP-related protein 2; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; IL-6DBP; interleukin 6-dependent DNA-binding protein; Interleukin-6-dependent-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; Nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; Silencer factor B; TCF-5; Transcription factor 5; transcription factor C/EBP beta

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Gene Aliases: C/EBP-beta; C/EBPbeta; CEBPB; CRP2; IL-6DBP; IL6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6; PP9092; Sfb; TCF5

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UniProt ID: (Human) P17676, (Mouse) P28033, (Rat) P21272

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Entrez Gene ID: (Human) 1051, (Mouse) 12608, (Rat) 24253

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Function(s)
RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding kinase binding histone acetyltransferase binding glucocorticoid receptor binding protein homodimerization activity histone deacetylase binding ubiquitin-like protein ligase binding protein heterodimerization activity sequence-specific DNA binding basic leucine zipper transcription factor
Process(es)
ovarian follicle development embryonic placenta development granuloma formation regulation of transcription, DNA-templated transcription from RNA polymerase II promoter acute-phase response inflammatory response immune response memory neuron differentiation positive regulation of interleukin-4 production mammary gland epithelial cell proliferation response to endoplasmic reticulum stress T-helper 1 cell activation negative regulation of T cell proliferation defense response to bacterium negative regulation of neuron apoptotic process regulation of interleukin-6 biosynthetic process positive regulation of fat cell differentiation positive regulation of osteoblast differentiation regulation of osteoclast differentiation negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter brown fat cell differentiation mammary gland epithelial cell differentiation regulation of transcription involved in cell fate commitment intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to interleukin-1 cellular response to organic cyclic compound hepatocyte proliferation liver regeneration positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress transcription, DNA-templated cell differentiation response to lipopolysaccharide fat cell differentiation positive regulation of transcription, DNA-templated
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