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Invitrogen
C/EBP beta Monoclonal Antibody (1H7)
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
Product Details
MA1-827
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H7
Immunogen
Recombinant mouse LIP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2078054
Product Specific Information
MA1-827 detects C/EBP beta protein in mouse and rat samples. MA1-827 detects the LAP*, LAP and LIP isoforms of C/EBP beta.
MA1-827 has successfully been used in Western blot, immunofluorescent and immunoprecipitation procedures. By Western blot, this antibody detects 38, 35 and 20 kDa proteins representing C/EBP beta LAP*, LAP, and LIP isoforms respectively, in 3T3-L1 cells. LIP is recognized as the C-terminus fragment. Immunofluorescent staining of C/EBP beta in P388D1 cells can be performed using MA1-827
The MA1-827 immunogen is recombinant mouse LIP.
Target Information
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AGP/EBP; C EBP; C/EBP BETA; C/EBP-related protein 2; CCAAT/enhancer-binding protein beta; IL-6DBP; Interleukin-6-dependent-binding protein; LAP; LIP; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; Silencer factor B
Gene Aliases: C/EBPbeta; Cebpb; CRP2; IL-6DBP; Il6dbp; LAP; LIP; NF-IL6; NF-M; Nfil6; Sfb; TCF5
UniProt ID: (Mouse) P28033, (Rat) P21272
Entrez Gene ID: (Mouse) 12608, (Rat) 24253
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
kinase binding
histone acetyltransferase binding
glucocorticoid receptor binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
ubiquitin-like protein ligase binding
protein heterodimerization activity
basic leucine zipper transcription factor
ovarian follicle development
embryonic placenta development
granuloma formation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell differentiation
neuron differentiation
response to lipopolysaccharide
positive regulation of interleukin-4 production
mammary gland epithelial cell proliferation
response to endoplasmic reticulum stress
T-helper 1 cell activation
negative regulation of T cell proliferation
defense response to bacterium
negative regulation of neuron apoptotic process
regulation of interleukin-6 biosynthetic process
fat cell differentiation
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
brown fat cell differentiation
mammary gland epithelial cell differentiation
regulation of transcription involved in cell fate commitment
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to amino acid stimulus
hepatocyte proliferation
liver regeneration
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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