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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
C/EBP α regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP α uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic α helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP α appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP β, C/EBP γ, C/EBP δ and C/EBP ε, all of which exhibit similar DNA-binding specificities and affinities to C/EBP α. Furthermore, C/EBP β and C/EBP δ readily form heterodimers both with each other as well as with C/EBP α.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C EBP; C/EBP delta; C/EBP epsilon; C/EBP-related protein 1; C/EBP-related protein 3; C/EBPdelta; C/EBPepsilon; CCAAT/enhancer binding protein (C/EBP), delta; CCAAT/enhancer binding protein (C/EBP), epsilon; CCAAT/enhancer binding protein , epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein delta; CCAAT/enhancer-binding protein epsilon; NF-IL6-beta; Nuclear factor NF-IL6-beta; Transcription factor CELF
Gene Aliases: C/EBP-delta; C/EBP-epsilon; C/EBPd; C/EBPe; C/EPBe; CEBPD; CEBPE; CELF; CRP1; CRP3; Gm294; NF-IL6-beta
UniProt ID: (Human) P49716, (Human) Q15744, (Mouse) Q00322, (Rat) Q03484, (Rat) P56261, (Mouse) Q6PZD9
Entrez Gene ID: (Human) 1052, (Human) 1053, (Mouse) 12609, (Rat) 25695, (Rat) 25410, (Mouse) 110794
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