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Immunogen sequence: VSNVWDGDRE CSGMKLLGIH EQAAVGFLTL MEALRYCKVG SYLKSPKFPI WIVGSETHLT VFFAKDMALV APEAPSEQAR RVFQTYDPED NGFIPDSLLE DVM
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%.
The protein encoded by this gene contains a caspase-associated recruitment domain and may function in apoptosis. It has been identified as a tumor suppressor in lung and gastric cancers, and a polymorphism in the gene may be associated with gastric cancer risk. Alternative splicing of this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CARD-containing protein; caspase recruitment domain containing pro-apoptotic protein; Dermal papilla-derived protein 5; Deubiquitinating enzyme MINDY-3; family with sequence similarity 188, member A; Protein CARP; RP11-394I23.1; Ubiquitin carboxyl-terminal hydrolase MINDY-3
Gene Aliases: C10orf97; CARP; DERP5; FAM188A; MINDY3; MST126; MSTP126; My042
UniProt ID: (Human) Q9H8M7
Entrez Gene ID: (Human) 80013
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