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Product Details
PA5-113977
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human C15orf27
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2884492
Product Specific Information
Immunogen sequence: EMEMVIQQYE KAKVIQDEQL ERLTQICQEQ GFEIRQLRAH LAQQDLDLAA
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Goat: 90%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
Target Information
C15orf27 is a voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, it does not form a functional ion channel and its precise role remains unclear. The protein undergoes both rapid and slow structural rearrangements in response to changes in voltage, and contains a zinc-binding site that can regulate the slow conformational transition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsHVRP1; hTMEM266; Hv1 related protein 1; HV1-related protein 1; Transmembrane protein 266; transmembrane protein C15orf27
Gene Aliases: C15orf27; HVRP1; TMEM266
UniProt ID: (Human) Q2M3C6
Entrez Gene ID: (Human) 123591
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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