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This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency.
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Protein Aliases: basic proline-rich peptide IB-1; C1 esterase; Complement C1s subcomponent; Complement C1s-1 subcomponent; Complement C1s-A subcomponent; Complement component 1 subcomponent s; Complement component 1 subcomponent s-A; Complement component 1, S subcomponent 1; complement component C1SA; serine protease
Gene Aliases: AA959438; AI255193; AI327365; C1S; C1s1; C1sa; r-gsp
UniProt ID: (Human) P09871, (Rat) Q6P6T1, (Mouse) Q8CG14
Entrez Gene ID: (Human) 716, (Rat) 192262, (Mouse) 50908
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