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Invitrogen
C9orf72 Recombinant Rabbit Monoclonal Antibody (GT1553-RB)
FIGURE: 1 / 5
C9orf72 Antibody (MA5-46915) in ICC/IF
Immunofluorescent analysis of C9orf72 in DIV10 rat E18 primary hippocampal neuron cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: C9orf72 stained by C9orf72 monoclonal antibody (Product # MA5-46915) diluted at 1:250. Red: Tau, a cytoskeleton marker, stained by Tau antibody [GT287] diluted at 1:500. Blue: Fluoroshield with DAPI.
Product Details
MA5-46915
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
GT1553-RB
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human C9orf72. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2937987
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
C9orf72 may play a role in endosomal trafficking and autophagy. It is known to interact with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPSases. C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome. Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Guanine nucleotide exchange factor C9orf72; Guanine nucleotide exchange factor C9orf72 homolog; protein C9orf72 homolog
Gene Aliases: AI840585; ALSFTD; C9orf72; DENND9; DENNL72; FTDALS; FTDALS1
UniProt ID: (Mouse) Q6DFW0, (Human) Q96LT7, (Rat) Q66HC3
Entrez Gene ID: (Mouse) 73205, (Human) 203228, (Rat) 313155
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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