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Product Details
MA1-19211
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Guinea pig
Host/Isotype
Mouse
/ IgM
Class
Monoclonal
Type
Antibody
Clone
121SLE
Immunogen
Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
TBS, pH 8
Contains
15mM sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Wet ice
RRID
AB_1087289
Product Specific Information
This antibody recognizes Sialyl Lewis a-containing glycolipids (extracellular plasma membrane leaflet antigens).
For IHC (P), heat mediated antigen retrieval in sodium citrate is recommended.
Target Information
Mucin glycoprotein is a Sialyl Lewis A structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis A and/or Lewis B blood group antigens. In normal tissues, sialyl Lewis A antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CA-19.9; CA19 9; CA19.9
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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