Product References
VANGL2 inhibits antiviral IFN-I signaling by targeting TBK1 for autophagic degradation.
Science advances
Hu Z,Xie Y,Lu J,Yang J,Zhang J,Jiang H,Li H,Zhang Y,Wu D,Zeng K,Bai X,Yu X
Fri Jun 23 00:00:00 EDT 2023
N protein of PEDV plays chess game with host proteins by selective autophagy.
Autophagy
Zhai X,Kong N,Zhang Y,Song Y,Qin W,Yang X,Ye C,Ye M,Tong W,Liu C,Zheng H,Yu H,Zhang W,Yang X,Zhang G,Tong G,Shan T
Tue Aug 01 00:00:00 EDT 2023
TOLLIP-mediated autophagic degradation pathway links the VCP-TMEM63A-DERL1 signaling axis to triple-negative breast cancer progression.
Autophagy
Zhang TM,Liao L,Yang SY,Huang MY,Zhang YL,Deng L,Hu SY,Yang F,Zhang FL,Shao ZM,Li DQ
Wed Mar 01 00:00:00 EST 2023
Modulation of virus-induced neuroinflammation by the autophagy receptor SHISA9 in mice.
Nature microbiology
Zheng Y,Wang L,Liu Q,Xian H,Zhang C,Cai S,Yang S,Jin S,Cui J
Mon May 01 00:00:00 EDT 2023
PRPF19 Limits Porcine Epidemic Diarrhea Virus Replication through Targeting and Degrading Viral Capsid Protein.
Journal of virology
Zhai X,Kong N,Wang C,Qin W,Dong S,Zhai H,Yang X,Ye C,Ye M,Li G,Tong W,Liu C,Zheng H,Yu H,Zhang W,Yang X,Tong G,Shan T
Tue Jan 31 00:00:00 EST 2023
BNIP3L/NIX-mediated mitophagy alleviates passive stress-coping behaviors induced by tumor necrosis factor-α.
Molecular psychiatry
Lu JJ,Wu PF,He JG,Li YK,Long LH,Yao XP,Yang JH,Chen HS,Zhang XN,Hu ZL,Chen Z,Wang F,Chen JG
Mon Mar 13 00:00:00 EDT 2023
Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy.
Cell & bioscience
Xia Q,Li Y,Xu W,Wu C,Zheng H,Liu L,Dong L
Tue Feb 21 00:00:00 EST 2023
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Journal of virology
Dong S,Kong N,Zhang Y,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed May 25 00:00:00 EDT 2022
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Journal of virology
Dong S,Kong N,Wang C,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed Jul 13 00:00:00 EDT 2022
Panax notoginseng saponins protect PC12 cells against Aβ induced injury via promoting parkin-mediated mitophagy.
Journal of ethnopharmacology
Jiang Y,Li H,Huang P,Li S,Li B,Huo L,Zhong J,Pan Z,Li Y,Xia X
Tue Mar 01 00:00:00 EST 2022
Therapeutic effects of total saikosaponins from Radix bupleuri against Alzheimer's disease.
Frontiers in pharmacology
Li J,Zou B,Cheng XY,Yang XH,Li J,Zhao CH,Ma RX,Tian JX,Yao Y
Tue Aug 09 00:00:00 EDT 2022
Selective autophagy controls the stability of TBK1 via NEDD4 to balance host defense.
Cell death and differentiation
Xie W,Jin S,Zhang C,Yang S,Wu Y,Zhao Y,Songyang Z,Cui J
Sat Jan 01 00:00:00 EST 2022
A detrimental role of NLRP6 in host iron metabolism during Salmonella infection.
Redox biology
Deng Q,Yang S,Sun L,Huang K,Dong K,Zhu Y,Cao Y,Li Y,Wu S,Huang R
Tue Feb 01 00:00:00 EST 2022
TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Liu D,Zhao Z,She Y,Zhang L,Chen X,Ma L,Cui J
Tue Feb 15 00:00:00 EST 2022
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Nature communications
Boland S,Swarup S,Ambaw YA,Malia PC,Richards RC,Fischer AW,Singh S,Aggarwal G,Spina S,Nana AL,Grinberg LT,Seeley WW,Surma MA,Klose C,Paulo JA,Nguyen AD,Harper JW,Walther TC,Farese RV
Fri Oct 07 00:00:00 EDT 2022
Isolation of ferret astrocytes reveals their morphological, transcriptional, and functional differences from mouse astrocytes.
Frontiers in cellular neuroscience
Roboon J,Hattori T,Nguyen DT,Ishii H,Takarada-Iemata M,Kannon T,Hosomichi K,Maejima T,Saito K,Shinmyo Y,Mieda M,Tajima A,Kawasaki H,Hori O
Tue Oct 25 00:00:00 EDT 2022
Autophagy Activation Induces p62-Dependent Autophagic Degradation of Dengue Virus Capsid Protein During Infection.
Frontiers in microbiology
Wu Y,Zhou T,Hu J,Liu Y,Jin S,Wu J,Guan X,Cui J
Sat Sep 16 00:00:00 EDT 2023
Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3.
Autophagy
Liu ZZ,Hong CG,Hu WB,Chen ML,Duan R,Li HM,Yue T,Cao J,Wang ZX,Chen CY,Hu XK,Wu B,Liu HM,Tan YJ,Liu JH,Luo ZW,Zhang Y,Rao SS,Luo MJ,Yin H,Wang YY,Xia K,Xu L,Tang SY,Hu RG,Xie H
Fri Oct 01 00:00:00 EDT 2021
Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Wang W,Qin Y,Song H,Wang L,Jia M,Zhao C,Gong M,Zhao W
Tue Jun 01 00:00:00 EDT 2021
METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America
Yang Z,Yang S,Cui YH,Wei J,Shah P,Park G,Cui X,He C,He YY
Tue Aug 31 00:00:00 EDT 2021
METTL14 facilitates global genome repair and suppresses skin tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America
Yang Z,Yang S,Cui YH,Wei J,Shah P,Park G,Cui X,He C,He YY
Tue Aug 31 00:00:00 EDT 2021
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Scientific reports
Schlütermann D,Berleth N,Deitersen J,Wallot-Hieke N,Friesen O,Wu W,Stuhldreier F,Sun Y,Berning L,Friedrich A,Mendiburo MJ,Peter C,Wiek C,Hanenberg H,Stefanski A,Stühler K,Stork B
Mon Jul 05 00:00:00 EDT 2021
PINK1-mediated mitophagy maintains pluripotency through optineurin.
Cell proliferation
Wang C,Liu K,Cao J,Wang L,Zhao Q,Li Z,Zhang H,Chen Q,Zhao T
Sat May 01 00:00:00 EDT 2021
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Cell death & disease
Zhang C,Nie P,Zhou C,Hu Y,Duan S,Gu M,Jiang D,Wang Y,Deng Z,Chen J,Chen S,Wang L
Wed Feb 24 00:00:00 EST 2021
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Biochemical pharmacology
Sun H,Ou T,Hu J,Yang Z,Lei Q,Li Y,Wang G,Li Y,Wu K,Wang S,Wu S
Sun Aug 01 00:00:00 EDT 2021
TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro.
Nature communications
Baek M,Choe YJ,Bannwarth S,Kim J,Maitra S,Dorn GW,Taylor JP,Paquis-Flucklinger V,Kim NC
Fri Mar 26 00:00:00 EDT 2021
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway.
Autophagy
Deng Z,Lim J,Wang Q,Purtell K,Wu S,Palomo GM,Tan H,Manfredi G,Zhao Y,Peng J,Hu B,Chen S,Yue Z
Fri May 01 00:00:00 EDT 2020
CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes.
Theranostics
Zhang W,Zhou M,Lu W,Gong J,Gao F,Li Y,Xu X,Lin Y,Zhang X,Ding L,Zhang Z,Li G,Chen X,Sun X,Zhu X,Xu P,Zhang Y
Mon Aug 02 00:00:00 EDT 2021
ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.
mBio
Bhushan J,Radke JB,Perng YC,Mcallaster M,Lenschow DJ,Virgin HW,Sibley LD
Tue Oct 06 00:00:00 EDT 2020
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration.
Nature communications
Choi I,Zhang Y,Seegobin SP,Pruvost M,Wang Q,Purtell K,Zhang B,Yue Z
Fri Mar 13 00:00:00 EDT 2020
Streptococcus pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like vesicles via NDP52-delocalization.
Communications biology
Ogawa M,Takada N,Shizukuishi S,Tomokiyo M,Chang B,Yoshida M,Kakuta S,Tanida I,Ryo A,Guan JL,Takeyama H,Ohnishi M
Mon Jan 13 00:00:00 EST 2020
GABARAPL2 Is Critical for Growth Restriction of Toxoplasma gondii in HeLa Cells Treated with Gamma Interferon.
Infection and immunity
Zhang Z,Gu H,Li Q,Zheng J,Cao S,Weng C,Jia H
Mon Apr 20 00:00:00 EDT 2020
TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress.
Molecular cell
An H,Ordureau A,Paulo JA,Shoemaker CJ,Denic V,Harper JW
Thu Jun 06 00:00:00 EDT 2019
Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3.
The EMBO journal
Houtman J,Freitag K,Gimber N,Schmoranzer J,Heppner FL,Jendrach M
Fri Feb 15 00:00:00 EST 2019
Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3.
The EMBO journal
Houtman J,Freitag K,Gimber N,Schmoranzer J,Heppner FL,Jendrach M
Fri Feb 15 00:00:00 EST 2019
Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab.
Oncogene
Wang D,Xu Q,Yuan Q,Jia M,Niu H,Liu X,Zhang J,Young CY,Yuan H
Wed May 01 00:00:00 EDT 2019
Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab.
Oncogene
Wang D,Xu Q,Yuan Q,Jia M,Niu H,Liu X,Zhang J,Young CY,Yuan H
Wed May 01 00:00:00 EDT 2019
Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury.
Scientific reports
Marek-Iannucci S,Thomas A,Hou J,Crupi A,Sin J,Taylor DJ,Czer LS,Esmailian F,Mentzer RM,Andres AM,Gottlieb RA
Wed Jul 10 00:00:00 EDT 2019
Activation of PINK1-Parkin-dependent mitophagy in Tri-ortho-cresyl phosphate-treated Neuro2a cells.
Chemico-biological interactions
Wang Y,Zhang C,Shen Z,Kou R,Xie K,Song F
Thu Aug 01 00:00:00 EDT 2019
A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats.
Nature communications
Ferreira JCB,Campos JC,Qvit N,Qi X,Bozi LHM,Bechara LRG,Lima VM,Queliconi BB,Disatnik MH,Dourado PMM,Kowaltowski AJ,Mochly-Rosen D
Fri Jan 18 00:00:00 EST 2019
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
Molecular cell
Jin S,Tian S,Luo M,Xie W,Liu T,Duan T,Wu Y,Cui J
Thu Oct 19 00:00:00 EDT 2017
Tetherin Suppresses Type I Interferon Signaling by Targeting MAVS for NDP52-Mediated Selective Autophagic Degradation in Human Cells.
Molecular cell
Jin S,Tian S,Luo M,Xie W,Liu T,Duan T,Wu Y,Cui J
Thu Oct 19 00:00:00 EDT 2017
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Cell
Zhong Z,Umemura A,Sanchez-Lopez E,Liang S,Shalapour S,Wong J,He F,Boassa D,Perkins G,Ali SR,McGeough MD,Ellisman MH,Seki E,Gustafsson AB,Hoffman HM,Diaz-Meco MT,Moscat J,Karin M
Thu Feb 25 00:00:00 EST 2016
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Cell
Zhong Z,Umemura A,Sanchez-Lopez E,Liang S,Shalapour S,Wong J,He F,Boassa D,Perkins G,Ali SR,McGeough MD,Ellisman MH,Seki E,Gustafsson AB,Hoffman HM,Diaz-Meco MT,Moscat J,Karin M
Thu Feb 25 00:00:00 EST 2016
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy.
Biochemical and biophysical research communications
Zhang J,Chen K,Wang L,Wan X,Shrestha C,Zhou J,Mo Z
Fri Aug 05 00:00:00 EDT 2016
Phosphatase and tensin homologue (PTEN)-induced putative kinase 1 reduces pancreatic β-cells apoptosis in glucotoxicity through activation of autophagy.
Biochemical and biophysical research communications
Zhang J,Chen K,Wang L,Wan X,Shrestha C,Zhou J,Mo Z
Fri Aug 05 00:00:00 EDT 2016
A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells.
mBio
Selleck EM,Orchard RC,Lassen KG,Beatty WL,Xavier RJ,Levine B,Virgin HW,Sibley LD
Tue Sep 08 00:00:00 EDT 2015
A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells.
mBio
Selleck EM,Orchard RC,Lassen KG,Beatty WL,Xavier RJ,Levine B,Virgin HW,Sibley LD
Tue Sep 08 00:00:00 EDT 2015
