Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Sequence of this protein is as follows: MAGELTPEEE AQYKKAFSAV DTDGNGTINA QELGAALKAT GKNLSEAQLR KLISEVDGDG DGEISFQEFL TAARKARAGL EDLQVAFRAF DQDGDGHITV DELRRAMAGL GQPLPQEELD AMIREADVDQ DGRVNYEEFA RMLAQE
This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: call5; calmodulin-like 5; Calmodulin-like protein 5; Calmodulin-like skin protein
Gene Aliases: CALML5; CLSP
UniProt ID: (Human) Q9NZT1
Entrez Gene ID: (Human) 51806
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