Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
CAP1 Antibody (PA5-89912) in WB
Western blot analysis of CAP1 in extracts of various cell lines. Samples were incubated with CAP1 Polyclonal antibody (Product # PA5-89912) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-89912
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CAP1 (NP_0063581)
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805839
Product Specific Information
Immunogen sequence: MADMQNLVER LERAVGRLEA VSHTSDMHRG YADSPSKAGA APYVQAFDSL LAGPVAEYLK ISKEIGGDVQ KHAEMVHTGL KLERALLVTA SQCQQPAENK; Positive Samples: HeLa, 293T, A-431, HepG2, Rat thymus, Mouse thymus; Cellular Location: Cell membrane, Peripheral membrane protein
Target Information
Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene. This gene is mapped to 1p34. 2. The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. And the human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: adenylyl cyclase-associated CAP protein, yeast homolog 1; Adenylyl cyclase-associated protein 1; CAP 1; CAP, adenylate cyclase-associated protein 1; cyclase-associated protein homologue; RP11-115D7.1; testis secretory sperm-binding protein Li 218p
Gene Aliases: CAP; CAP1; CAP1-PEN; Mch1
UniProt ID: (Human) Q01518, (Rat) Q08163, (Mouse) P40124
Entrez Gene ID: (Human) 10487, (Rat) 64185, (Mouse) 12331
cell morphogenesis
ameboidal-type cell migration
receptor-mediated endocytosis
establishment or maintenance of cell polarity
signal transduction
activation of adenylate cyclase activity
actin polymerization or depolymerization
biological_process
actin cytoskeleton organization
cytoskeleton organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support