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FIGURE: 1 / 3
CAR Antibody (PA5-31175) in ICC/IF
CAR Polyclonal Antibody detects Coxsackie Adenovirus Receptor protein at cell membrane by immunofluorescent analysis. Sample: NT2D1 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Coxsackie Adenovirus Receptor stained by CAR Polyclonal Antibody (Product # PA5-31175) diluted at 1:500. Blue: Fluoroshield with DAPI . Scale bar= 10 µm.
Product Details
PA5-31175
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 36 and 358 of Human CAR
Conjugate
Form
Liquid
Concentration
1.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2548649
Product Specific Information
Recommended positive controls: A549, H1299, HCT116.
Predicted reactivity: Mouse (90%), Rat (90%), Rabbit (90%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CAR; Coxsackievirus and adenovirus receptor; Coxsackievirus and adenovirus receptor homolog; Coxsackievirus B-adenovirus receptor; CVB3-binding protein; HCVADR; rCAR
Gene Aliases: CAR; Car1; CAR4/6; CXADR; HCAR
UniProt ID: (Human) P78310, (Rat) Q9R066
Entrez Gene ID: (Human) 1525, (Rat) 89843
mitochondrion organization
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
heart development
germ cell migration
epithelial structure maintenance
neutrophil chemotaxis
actin cytoskeleton reorganization
cell-cell junction organization
gamma-delta T cell activation
viral entry into host cell
cardiac muscle fiber development
regulation of immune response
leukocyte migration
transepithelial transport
AV node cell to bundle of His cell communication
single organismal cell-cell adhesion
homotypic cell-cell adhesion
defense response to virus
negative regulation of cardiac muscle cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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