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Product Details
PA5-93043
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 469-748 of human CARS (NP_0017421)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806599
Product Specific Information
Immunogen sequence: ILRAPVDITG QFEKWGEEEA ELNKNFYDKK TAIHKALCDN VDTRTVMEEM RALVSQCNLY MAARKAVRKR PNQALLENIA LYLTHMLKIF GAVEEDSSLG FPVGGPGTSL SLEATVMPYL QVLSEFREGV RKIAREQKVP EILQLSDALR DNILPELGVR FEDHEGLPTV VKLVDRNTLL KEREEKRRVE EEKRKKKEEA ARRKQEQEAA KLAKMKIPPS EMFLSETDKY SKFDENGLPT HDMEGKELSK GQAKKLKKLF EAQEKLYKEY LQMAQNGSFQ; Positive Samples: HeLa, MCF7, Mouse liver; Cellular Location: Cytoplasm
Target Information
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CysRS; cysteine translase; cysteine tRNA ligase 1, cytoplasmic; Cysteine--tRNA ligase, cytoplasmic; Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase, cytoplasmic
Gene Aliases: CA3; CARS; CARS1; CYSRS; MGC:11246
UniProt ID: (Human) P49589, (Mouse) Q9ER72
Entrez Gene ID: (Human) 833, (Mouse) 27267
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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