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Product Details
CF502564
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1B8
Immunogen
Full length human recombinant protein of human CAT produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Catalase; CTA1; HGNC:1516; MGC138422; MGC138424
Gene Aliases: CAT
UniProt ID: (Human) P04040
Entrez Gene ID: (Human) 847
response to reactive oxygen species
osteoblast differentiation
ureteric bud development
response to hypoxia
purine nucleotide catabolic process
triglyceride metabolic process
aging
cholesterol metabolic process
aerobic respiration
response to light intensity
UV protection
response to ozone
response to lead ion
positive regulation of phosphatidylinositol 3-kinase signaling
response to activity
response to inactivity
hemoglobin metabolic process
negative regulation of NF-kappaB transcription factor activity
response to estradiol
response to insulin
response to vitamin A
response to vitamin E
response to L-ascorbic acid
response to drug
response to hydrogen peroxide
hydrogen peroxide catabolic process
negative regulation of apoptotic process
response to ethanol
response to cadmium ion
positive regulation of NF-kappaB transcription factor activity
protein tetramerization
protein homotetramerization
positive regulation of cell division
response to hyperoxia
response to fatty acid
cellular response to growth factor stimulus
response to phenylpropanoid
cellular oxidant detoxification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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