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Immunogen sequence: ISRKHYKQIA QAAFNLKMRA ACTGRTEYPK IRTFDGREHS TNSVNQDLLE AEKWTHIEGN VDIGDLTWEQ KEKVLRLLFA KMNGCPSRKY NQSSRPPVPD YVVSDSGETK EFGDESKLQD KIFITQQIAI SDSSGEVVLP TIPKEPQ
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 72%.
Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Basal body-orientation factor 1; coiled-coil domain containing 176; Coiled-coil domain-containing protein 176
Gene Aliases: BBOF1; C14orf45; CCDC176
UniProt ID: (Human) Q8ND07
Entrez Gene ID: (Human) 80127
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