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Product Details
MA5-30139
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
02
Immunogen
Recombinant Human CCL16/HCC-4/NCC4 Protein (Gln24-Gln120)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785914
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human CCL16/HCC-4/NCC4.
Target Information
CCL16 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL16 displays chemotactic activity for lymphocytes and monocytes but not for neutrophils. This cytokine also shows a potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. The expression of this gene is upregulated by IL-10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-C motif chemokine 16; chemokine (C-C motif) ligand 16; Chemokine CC-4; Chemokine LEC; HCC-4; IL-10-inducible chemokine; LCC-1; liver CC chemokine-1; Liver-expressed chemokine; LMC; Lymphocyte and monocyte chemoattractant; MGC117051; Monotactin-1; MTN-1; NCC-4; new CC chemokine 4; small inducible cytokine subfamily A (Cys-Cys), member 16; Small-inducible cytokine A16
Gene Aliases: CCL16; CKb12; HCC-4; ILINCK; LCC-1; LEC; LMC; Mtn-1; NCC-4; NCC4; SCYA16; SCYL4
UniProt ID: (Human) O15467
Entrez Gene ID: (Human) 6360
monocyte chemotaxis
chemotaxis
inflammatory response
cell communication
G-protein coupled receptor signaling pathway
cell-cell signaling
neutrophil chemotaxis
positive regulation of GTPase activity
lymphocyte chemotaxis
positive regulation of inflammatory response
positive chemotaxis
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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