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Product Details
MA5-23300
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
4G8
Immunogen
CCL4L1 (NP_996890, 28 a.a. ~ 93 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606514
Product Specific Information
Peptide Sequence: SDPPTACCFS YTARKLPRNF VVDYYETSSL CSQPAVVFQT KRGKQVCADP SESWVQEYVY DLELN*
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to CCL4 which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more telomeric gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACT-2; C-C motif chemokine 4; C-C motif chemokine 4-like; CC chemokine ligand 4L1; chemokine (C-C motif) ligand 4-like 1; chemokine (C-C motif) ligand 4-like 1, telomeric; G-26 T-lymphocyte-secreted protein; HC21; LAG-1; lymphocyte activation gene 1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1b2; MIP-1-beta; MIP-1-beta(1-69); Monocyte adherence-induced protein 5-alpha; PAT 744; Protein H400; SIS-gamma; small inducible cytokine A4-like; Small-inducible cytokine A4; Small-inducible cytokine A4-like; T-cell activation protein 2
Gene Aliases: AT744.2; CCL4; CCL4L; CCL4L1; CCL4L2; LAG-1; LAG1; MIP-1-beta; MIP1B; SCYA4; SCYA4L; SCYA4L1; SCYA4L2
UniProt ID: (Human) Q569J2
Entrez Gene ID: (Human) 388372
monocyte chemotaxis
inflammatory response
G-protein coupled receptor signaling pathway
neutrophil chemotaxis
positive regulation of GTPase activity
lymphocyte chemotaxis
positive regulation of inflammatory response
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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