Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: EYKKGESQTD IEITREEDFT RILQMEEEYI QQLCEDIIQL KPDVVITEKG ISDLAQHYLM RANITAIRRV RKTDNNRIAR ACGARIVSRP EELREDDVGT GAGLLEIKKI GDEYFTFITD CKDPKACTIL LRGASKEILS EVERNLQDAM QVCRNVLLDP QLVPGGGASE MAVAHALTEK SKAMTGVEQW PYRAVAQALE VIPRTLIQNC GASTIRLLTS LRAKHTQENC ETWGVNGETG TLVDMKELGI WEPLAVKLQT YKTAVETAVL LLRIDDIVSG HKKKGDDQSR QGGAPDAGQE
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants have been characterized for this gene. In addition, a pseudogene of this gene has been found on chromosome 8.
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Protein Aliases: CCT-gamma; Chaperonin containing T-complex polypeptide 1 subunit 3; chaperonin containing TCP1, subunit 3 (gamma); chaperonin subunit 3 (gamma); hTRiC5; Matricin; mTRiC-P5; OTTHUMP00000025735; T-complex protein 1 subunit gamma; T-complex protein 1, gamma subunit; TCP-1-gamma; TCP1 (t-complex-1) ring complex, polypeptide 5
Gene Aliases: AL024092; CCT-gamma; CCT3; CCTG; PIG48; TCP-1-gamma; Tcp1-rs3; TriC-P5; TRIC5
UniProt ID: (Human) P49368, (Mouse) P80318
Entrez Gene ID: (Human) 7203, (Mouse) 12462
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