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Product Details
19793-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The antibody has no cross reaction to CCT6B.
Target Information
The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 alpha, beta, gamma, delta, epsilon, zeta, eta and theta, each encoded by a different gene. Two zeta subunits have been described: TCP-1 zeta (also designated TCP-1 zeta1) and TCP-1 zeta2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acute morphine dependence related protein 2; Acute morphine dependence-related protein 2; amino acid transport defect-complementing; CCT zeta-1; CCT zeta1; CCT- zeta-1; CCT- zeta1; CCT-zeta-1; Chaperonin containing T-complex polypeptide 1 subunit 6A; chaperonin containing T-complex subunit 6; chaperonin containing TCP-1; chaperonin containing TCP1, subunit 6A (zeta 1); chaperonin subunit 6a (zeta); histidine transp; histidine transport regulator 3; HTR3; T-complex protein 1 subunit zeta; T-complex protein 1, zeta subunit; TCP 1 zeta; TCP-1- zeta; TCP-1-zeta; TCP1 zeta; TCP1- zeta; Tcp20
Gene Aliases: CCT-zeta; CCT-zeta-1; CCT6; CCT6A; CCTZ; Cctz-1; Cctz1; HTR3; MoDP-2; TCP-1-zeta; TCP20; TCPZ; TTCP20
UniProt ID: (Human) P40227, (Mouse) P80317
Entrez Gene ID: (Human) 908, (Mouse) 12466
protein folding
positive regulation of telomere maintenance via telomerase
protein stabilization
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
binding of sperm to zona pellucida
toxin transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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