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Product Details
CL594-67540
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C1G1
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
593/614 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: LNVELELKAE KDNAEIRVHT VEDYQAIVDA EWNILYDKLE KIHHSGAKVV LSKLPIGDVA TQYFADRDMF CAGRVPEEDL KRTMMACGGS IQTSVNALSA DVLGRCQVFE ETQIGGERYN FFTGCPKAKT CTFILRGGAE QFMEETERSL HDAIMIVRRA IKNDSVVAGG GAIEMELSKY LRDYSRTIPG KQQLLIGAYA KALEIIPRQL CDNAGFDATN ILNKLRARHA QGGTWYGVDI NNEDIADNFE AFVWEPAMVR INALTAASEA ACLIVSVDET IKNPRSTVDA PTAAGRGRGR GRPH
Target Information
The TCP1 eta gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CCT-eta; Chaperonin containing T-complex polypeptide 1 subunit 7; chaperonin containing t-complex polypeptide 1, eta subunit; chaperonin containing t-complex subunit eta; chaperonin subunit 7 (eta); HIV-1 Nef interacting protein; HIV-1 Nef-interacting protein; MGC110985; T-complex protein 1 subunit eta; TCP-1-eta
Gene Aliases: AA408524; AL022769; CCT7; CCTETA; CCTH; Cctz; NIP7-1; TCP1ETA
UniProt ID: (Human) Q99832, (Mouse) P80313
Entrez Gene ID: (Human) 10574, (Mouse) 12468
protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
toxin transport
positive regulation of establishment of protein localization to telomere
positive regulation of protein localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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